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Images
Published: 01 September 2024
VASCULOPATHY ASSOCIATED WITH HIV Figure 9-11 VASCULOPATHY ASSOCIATED WITH HIV A: Cerebral artery with severe intimal thickening and narrowing (endarteritis obliterans). B: HIV vasculitis in a cerebral artery, with lymphocytes infiltrating through the vessel wall. More about this image found in VASCULOPATHY ASSOCIATED WITH HIV A: Cerebral artery with severe intimal th...
Images
Published: 01 September 2024
SKIN BIOPSY IN PATIENT WITH MENINGOCOCCEMIA Figure 11-10 SKIN BIOPSY IN PATIENT WITH MENINGOCOCCEMIA A: Hematoxylin and eosin (H&E) stain (left) shows leukocytoclastic vasculitis. B: Scant intracellular cocci are seen with immunohistochemistry. (A,B: courtesy of the CDC IDPB) More about this image found in SKIN BIOPSY IN PATIENT WITH MENINGOCOCCEMIA A: Hematoxylin and eosin (H&am...
Images
Published: 01 September 2024
SUBACUTE SCLEROSING PANENCEPHALITIS Figure 3-25 SUBACUTE SCLEROSING PANENCEPHALITIS At autopsy, perivascular mononuclear cell cuffing (without vasculitis) is often more conspicuous than meningeal inflammation. Violaceous smudged viral inclusions can be found within neuronal nuclei (arrow and inse... More about this image found in SUBACUTE SCLEROSING PANENCEPHALITIS At autopsy, perivascular mononuclear c...
Images
Published: 01 September 2024
INHALATION ANTHRAX Figure 14-11 INHALATION ANTHRAX A mediastinal lymph node shows prominent hemorrhage (A) and associated neutrophil infiltration (B), also involving the perinodal fat. Parietal pleural biopsy (C) in a patient with inhalation anthrax shows edema, vasculitis, and associated hemorrh... More about this image found in INHALATION ANTHRAX A mediastinal lymph node shows prominent hemorrhage (A)...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-14
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
...) and noninfectious causes of similar gastrointestinal symptoms (e.g., vasculitis such as polyarteritis nodosa) 25-60% Inhalational 4-10 days Biphasic presentation: initially as a flu-like illness, followed by respiratory manifestations such dyspnea, cough, and persistent pleural effusions, ending with severe...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-11
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... mixed (mononuclear cell and neutrophil) meningeal and choroid plexus inflammation and ventriculitis ( 9 ). A degree of vasculitis can also be seen, sometimes with associated blood vessel thrombosis. The inflammatory infiltrate frequently extends into the brain cortex, and forms abscesses. Bacteria can...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-06
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., and CNS involvement (including vasculitis with secondary ischemic events). Congenital varicella can occur in the setting of maternal varicella or zoster during pregnancy. The syndrome in the newborn includes brain abnormalities that lead to developmental delay, chorioretinitis, cataracts, limb hypoplasia...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-17
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... is affected, the disease is called Parinaud oculoglandular syndrome Although rare, heart and neurologic complications can occur B. henselae Systemic Mimics manifestations of autoimmune disease, such as juvenile arthritis, myositis, leukocytoclastic vasculitis, and Henoch-Schoenlein purpura...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-28
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., and arthralgia. Lymphadenopathy, bronchospasm, cough, and a pruritic rash are also observed. Some patients have features of vasculitis and nonspecific rheumatic symptoms. Individuals with cardiac sarcocystosis may have atrial enlargement and electrocardiogram (ECG) abnormalities. Laboratory abnormalities...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-03
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... mononuclear cell cuffing without vasculitis is seen, a fairly generic feature of all viral infections in the nervous system ( fig. 3-18 ). No pathognomonic viral inclusions are present. EARLY POLIOMYELITIS Figure 3-16 EARLY POLIOMYELITIS CNS histology shows hypercellularity due to microgliosis (circled...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-25
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... muscle are sometimes examined. Irrespective of the site, the histologic features typically include various combinations of necrosis, predominantly mononuclear inflammation, vasculitis, fibrosis, and associated parasitic organisms. In immunocompetent individuals, pathology is most often identified...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-08
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... of parvovirus B19 infection. These include virus-associated hemophagocytic syndrome, pancytopenia, myocarditis, glomerulopathy, hepatitis, aseptic meningitis, encephalitis, and vasculitis. Pathologic Findings Parvovirus B19 skin lesions usually have nonspecific histologic features, which include superficial...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-09
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... a range of neurologic clinicopathologic conditions as a direct consequence of infection, as well as opportunistic infections and tumors ( Table 9-3 ) ( 11 , 12 ). Table 9-3 CENTRAL NERVOUS SYSTEM PATHOLOGIES DIRECTLY CAUSED BY HIV Vasculopathies and stroke HIV vasculitis HIV direct CNS tissue...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-05
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... various systemic manifestations, including vasculitis, arthritis, and glomerulonephritis, and are most frequent with chronic HBV infection. Pathologic Findings The liver pathology in the various hepatotropic viral infections is similar, although unique features are often seen with certain infections...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-04
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., sometimes associated with mild steatosis) and heart (myocarditis, sometimes associated with a serosanguinous effusion). Vasculitis occurs almost exclusively in the skin. Subcarinal and other mediastinal lymph nodes, as well as the bone marrow, may show evidence of erythrophagocytosis. Often...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-12
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... and macrophages, with associated fibrin, and sometimes, leukocytoclastic debris ( fig. 12-8 ) ( 18 ). Small vessel vasculitis, hemorrhages, and rarely, necrosis can be present. LEGIONNAIRES’ DISEASE Figure 12-8 LEGIONNAIRES’ DISEASE A: Prominent intra-alveolar inflammatory infiltrate with fibrin is seen...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-15
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... to systemic manifestations such as fever, lymphadenitis, uveitis, and small vessel vasculitis, as well as painful new lesions. This reaction is also called erythema nodosum leprosum ( fig. 15-16 ). ERYTHEMA NODOSUM LEPROSUM Figure 15-16 ERYTHEMA NODOSUM LEPROSUM Also known as type 2 leprosy...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-21
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... fibrosis, DAD, solitary well-formed or miliary granulomas ( fig. 21-22 ), abundant intra-alveolar macrophages, striking interstitial pneumonitis with lymphocytes, thin-walled cyst formation, calcification, minimal inflammation, and fungal vascular invasion with vasculitis. In all of these patterns...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch30
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
...Table 30-1 MAJOR VASCULITIS SYNDROMES Vessels Involved Histologic Features Comment Takayasu aortitis Aorta (all portions), and elastic branches of aorta Medal inflammation and necrosis with giant cells, adventitial and intimal scarring Isolated ascending aortitis has similar...
Images
Published: 15 November 2023
ISOLATED CORONARY VASCULITIS: RIGHT CORONARY ARTERY Figure 6-9 ISOLATED CORONARY VASCULITIS: RIGHT CORONARY ARTERY A brisk lymphocytic inflammatory infiltrate nearly replaces the media, with a fibrotically thickened intima indicating the chronicity of the process. More about this image found in ISOLATED CORONARY VASCULITIS: RIGHT CORONARY ARTERY A brisk lymphocytic in...
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