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vasculiti

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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch30
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
...Table 30-1 MAJOR VASCULITIS SYNDROMES Vessels Involved Histologic Features Comment Takayasu aortitis Aorta (all portions), and elastic branches of aorta Medal inflammation and necrosis with giant cells, adventitial and intimal scarring Isolated ascending aortitis has similar...
Images
ISOLATED CORONARY <span class="search-highlight">VASCULITIS</span>: RIGHT CORONARY ARTERY  A brisk lymphocytic in...
Published: 15 November 2023
ISOLATED CORONARY VASCULITIS: RIGHT CORONARY ARTERY Figure 6-9 ISOLATED CORONARY VASCULITIS: RIGHT CORONARY ARTERY A brisk lymphocytic inflammatory infiltrate nearly replaces the media, with a fibrotically thickened intima indicating the chronicity of the process. More about this image found in ISOLATED CORONARY VASCULITIS: RIGHT CORONARY ARTERY A brisk lymphocytic in...
Images
<span class="search-highlight">VASCULITIS</span> MIMICS: MEDIUM-SIZED VESSELS  An ischemic artery is present, wit...
Published: 15 November 2023
VASCULITIS MIMICS: MEDIUM-SIZED VESSELS Figure 30-1 VASCULITIS MIMICS: MEDIUM-SIZED VESSELS An ischemic artery is present, with fibrinoid necrosis and marked inflammation. The patient had gangrene secondary to peripheral vascular disease without evidence of vasculitis. More about this image found in VASCULITIS MIMICS: MEDIUM-SIZED VESSELS An ischemic artery is present, wit...
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<span class="search-highlight">VASCULITIS</span> MIMICS: SMALL VESSELS  Left: Vasa vasorum inflammation shows lym...
Published: 15 November 2023
VASCULITIS MIMICS: SMALL VESSELS Figure 30-2 VASCULITIS MIMICS: SMALL VESSELS Left: Vasa vasorum inflammation shows lymphocytes and neutrophils marginating within the lumen and vascular wall. Right: Reactive lymphocytic vascular inflammation of a hip prosthesis with endothelial swelling. More about this image found in VASCULITIS MIMICS: SMALL VESSELS Left: Vasa vasorum inflammation shows lym...
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SEPTIC “<span class="search-highlight">VASCULITIS</span>” (INFECTIOUS PSEUDOANEURYSM)  There is intimal thickenin...
Published: 15 November 2023
SEPTIC “VASCULITIS” (INFECTIOUS PSEUDOANEURYSM) Figure 30-3 SEPTIC “VASCULITIS” (INFECTIOUS PSEUDOANEURYSM) There is intimal thickening, luminal thrombosis, and acute inflammation, with destruction of a large portion of this mesenteric arterial media extending into the adventitia and adjacent sof... More about this image found in SEPTIC “VASCULITIS” (INFECTIOUS PSEUDOANEURYSM) There is intimal thickenin...
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CRYOGLOBULINEMIA: RENAL BIOPSY  Left: The small vessel <span class="search-highlight">vasculitis</span> shows end...
Published: 15 November 2023
CRYOGLOBULINEMIA: RENAL BIOPSY Figure 30-37 CRYOGLOBULINEMIA: RENAL BIOPSY Left: The small vessel vasculitis shows endothelial swelling, transmural inflammation and necrosis, and admixed proteinaceous material. Right: Other vessels in the biopsy show mural inflammation with neutrophils, without ... More about this image found in CRYOGLOBULINEMIA: RENAL BIOPSY Left: The small vessel vasculitis shows end...
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POLYARTERITIS NODOSA-LIKE <span class="search-highlight">VASCULITIS</span>: TESTIS  Low-power magnification shows...
Published: 15 November 2023
POLYARTERITIS NODOSA-LIKE VASCULITIS: TESTIS Figure 30-40 POLYARTERITIS NODOSA-LIKE VASCULITIS: TESTIS Low-power magnification shows two arterial branches with concentric fibrinoid necrosis. More about this image found in POLYARTERITIS NODOSA-LIKE VASCULITIS: TESTIS Low-power magnification shows...
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LEUKOCYTOCLASTIC <span class="search-highlight">VASCULITIS</span>: SKIN  Left: Low-power magnification shows patc...
Published: 15 November 2023
LEUKOCYTOCLASTIC VASCULITIS: SKIN Figure 30-41 LEUKOCYTOCLASTIC VASCULITIS: SKIN Left: Low-power magnification shows patchy inflammation in the superficial dermis. Above: High-power magnification demonstrates leukocytoclasia, fibrinoid necrosis, and mild endothelial swelling. More about this image found in LEUKOCYTOCLASTIC VASCULITIS: SKIN Left: Low-power magnification shows patc...
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SEPTIC <span class="search-highlight">VASCULITIS</span>: <em>NEISSERIA</em> SEPSIS  Although sepsis can r...
Published: 15 November 2023
SEPTIC VASCULITIS: NEISSERIA SEPSIS Figure 30-42 SEPTIC VASCULITIS: NEISSERIA SEPSIS Although sepsis can result in antigen-antibody complex small vessel cutaneous vasculitis, more often there is a neutrophilic infiltrate destroying small and medium-sized vessels and extending into the adventitia, reflecting infection. (Left: H&E stain; right: tissue Gram stain showing the diplococci (black arrow). More about this image found in SEPTIC VASCULITIS: NEISSERIA SEPSIS Although sepsis can r...
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RHEUMATOID <span class="search-highlight">VASCULITIS</span>: MUSCLE BIOPSY  There is transmural inflammation, thr...
Published: 15 November 2023
RHEUMATOID VASCULITIS: MUSCLE BIOPSY Figure 30-44 RHEUMATOID VASCULITIS: MUSCLE BIOPSY There is transmural inflammation, thrombosis, and a suggestion of fibrinoid necrosis in a small muscular artery. More about this image found in RHEUMATOID VASCULITIS: MUSCLE BIOPSY There is transmural inflammation, thr...
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POLYARTERITIS NODOSA: NERVE BIOPSY  The artery at the left has perivascular...
Published: 15 November 2023
POLYARTERITIS NODOSA: NERVE BIOPSY Figure 30-43 POLYARTERITIS NODOSA: NERVE BIOPSY The artery at the left has perivascular inflammation and acute thrombus and is considered probable vasculitis. The vessel on the right is diagnostic, as there is fibrinoid necrosis. As muscular arteries are involve... More about this image found in POLYARTERITIS NODOSA: NERVE BIOPSY The artery at the left has perivascular...
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POLYARTERITIS NODOSA  Polyarteritis nodosa usually manifests as a systemic ...
Published: 15 November 2023
POLYARTERITIS NODOSA Figure 6-8 POLYARTERITIS NODOSA Polyarteritis nodosa usually manifests as a systemic vasculitis with patchy involvement of the coronary arteries. More about this image found in POLYARTERITIS NODOSA Polyarteritis nodosa usually manifests as a systemic ...
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GRANULOMATOSIS WITH POLYANGIITIS  Basophilic necrosis at the top right cons...
Published: 15 November 2023
GRANULOMATOSIS WITH POLYANGIITIS Figure 30-29 GRANULOMATOSIS WITH POLYANGIITIS Basophilic necrosis at the top right consists of karyorrhectic neutrophils; the inflammation involves an adjacent artery wall. The vasculitis of granulomatosis with polyangiitis often appears secondary and fibrinoid ne... More about this image found in GRANULOMATOSIS WITH POLYANGIITIS Basophilic necrosis at the top right cons...
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ALLOGRAFT VASCULOPATHY  A,B: Intimal fibroplasia causing somewhat concentri...
Published: 15 November 2023
ALLOGRAFT VASCULOPATHY Figure 24-10 ALLOGRAFT VASCULOPATHY A,B: Intimal fibroplasia causing somewhat concentric luminal narrowing (A) without disruption of the internal elastic membrane (B) (elastic stain). C: Vascular injury, in the form of small vessel vasculitis, may also be seen with thrombu... More about this image found in ALLOGRAFT VASCULOPATHY A,B: Intimal fibroplasia causing somewhat concentri...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch06
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... NODOSA Figure 6-8 POLYARTERITIS NODOSA Polyarteritis nodosa usually manifests as a systemic vasculitis with patchy involvement of the coronary arteries. ISOLATED CORONARY VASCULITIS: RIGHT CORONARY ARTERY Figure 6-9 ISOLATED CORONARY VASCULITIS: RIGHT CORONARY ARTERY A brisk lymphocytic...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch24
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... Moderate rejection Two or more foci of inflammatory infiltrate with associated myocyte injury 3R Severe rejection Diffuse inflammatory infiltrate with multifocal myocyte injury ± edema, ± hemorrhage, ± vasculitis a Table 1 from reference 22 . Table 24-5 INTERNATIONAL SOCIETY FOR HEART...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch29
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
...), thrombosis associated with coagulopathies, and vasculitis. Clinical Features. Peripheral vascular disease is suspected if there is a pressure ratio of the ankle to brachial arteries, and is confirmed by vascular imaging. Treatment with lipid-lowering therapy may slow the progression of disease in some...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch33
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
..., especially adenocarcinoma, it is considered a manifestation of Trousseau syndrome. Because it may mimic vasculitis clinically, histologic assessment is often required for the diagnosis. The fibrin loses its fibrillar appearance and coalesces into homogeneous eosinophilic masses with entrapped degenerative...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch03
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
..., it is not necessary to orient most aortic or pulmonary arterial specimens prior to sectioning. To evaluate for vasculitis or luminal obstruction, cross sections of muscular arteries are strongly preferred. However, when evaluating for fibromuscular dysplasia, the vessel should be embedded and cut longitudinally...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch55
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... diagnosis is often unsuspected in such cases and the diagnosis is made by the surgical pathologist ( 72 ). The tumor may initially manifest as renal artery stenosis (renovascular hypertension), aortic rupture, systemic vasculitis, and bowel ischemia caused by embolic tumor ( 63 , 73 – 76 ). The tumor may...