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UNICYSTIC AMELOBLASTOMA (UA) VARIANTS A: Luminal variant where the feature...
Available to PurchasePublished: 01 June 2025
UNICYSTIC AMELOBLASTOMA (UA) VARIANTS Figure 5-51 UNICYSTIC AMELOBLASTOMA (UA) VARIANTS A: Luminal variant where the features of ameloblastoma are seen only in the luminal cystic epithelium. B: Intraluminal variant of UA where the solid portion of the neoplasm grows exclusively into the lumen More about this image found in UNICYSTIC AMELOBLASTOMA (UA) VARIANTS A: Luminal variant where the feature...
Images
CENTRAL ODONTOGENIC FIBROMA Amyloid-rich variant with small cords and nest...
Available to PurchasePublished: 01 June 2025
CENTRAL ODONTOGENIC FIBROMA Figure 5-96 CENTRAL ODONTOGENIC FIBROMA Amyloid-rich variant with small cords and nests of odontogenic epithelium with rounded amorphous eosinophilic pools of secreted amyloid protein (odontogenic ameloblast-associated protein [ODAM]). More about this image found in CENTRAL ODONTOGENIC FIBROMA Amyloid-rich variant with small cords and nest...
Images
CENTRAL ODONTOGENIC FIBROMA, GRANULAR CELL VARIANT The stromal component c...
Available to PurchasePublished: 01 June 2025
CENTRAL ODONTOGENIC FIBROMA, GRANULAR CELL VARIANT Figure 5-99 CENTRAL ODONTOGENIC FIBROMA, GRANULAR CELL VARIANT The stromal component consists of large polygonal cells with abundant granular cytoplasm. More about this image found in CENTRAL ODONTOGENIC FIBROMA, GRANULAR CELL VARIANT The stromal component c...
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BOTRYOID ODONTOGENIC CYST Multicystic variant of the lateral periodontal c...
Available to PurchasePublished: 01 June 2025
BOTRYOID ODONTOGENIC CYST Figure 5-162 BOTRYOID ODONTOGENIC CYST Multicystic variant of the lateral periodontal cyst. More about this image found in BOTRYOID ODONTOGENIC CYST Multicystic variant of the lateral periodontal c...
Images
CENTRAL GIANT CELL GRANULOMA (CGCG) A: The aggressive variant can grow rap...
Available to PurchasePublished: 01 June 2025
CENTRAL GIANT CELL GRANULOMA (CGCG) Figure 5-216 CENTRAL GIANT CELL GRANULOMA (CGCG) A: The aggressive variant can grow rapidly. B: Cephalometric radiograph of the lesion shows the extent of involvement, with bowing of the mandible. C: The anterior mandible is the most common location for CGCG More about this image found in CENTRAL GIANT CELL GRANULOMA (CGCG) A: The aggressive variant can grow rap...
Images
ODONTOGENIC KERATOCYST Rarely, “solid” variants of odontogenic keratocyst ...
Available to PurchasePublished: 01 June 2025
ODONTOGENIC KERATOCYST Figure 5-155 ODONTOGENIC KERATOCYST Rarely, “solid” variants of odontogenic keratocyst are reported. More about this image found in ODONTOGENIC KERATOCYST Rarely, “solid” variants of odontogenic keratocyst ...
Images
NEUROFIBROMA A: The unencapsulated lesion is composed of spindle cells wit...
Available to PurchasePublished: 01 June 2025
NEUROFIBROMA Figure 4-45 NEUROFIBROMA A: The unencapsulated lesion is composed of spindle cells with a myxoid stroma. B: Buckled or wavy nuclei are within collagenous stroma with myxoid change. C: The plexiform variant shows numerous nerves with a multinodular and serpentine growth pattern. D More about this image found in NEUROFIBROMA A: The unencapsulated lesion is composed of spindle cells wit...
Images
SPINDLE CELL/PLEOMORPHIC LIPOMA A: Spindle cell lipoma consists of bland s...
Available to PurchasePublished: 01 June 2025
SPINDLE CELL/PLEOMORPHIC LIPOMA Figure 7-43 SPINDLE CELL/PLEOMORPHIC LIPOMA A: Spindle cell lipoma consists of bland spindle cells in a collagenous stroma and varying amounts of mature adipose tissue. B: In pleomorphic lipoma, which is a variant of spindle cell lipoma, many of the stromal cells More about this image found in SPINDLE CELL/PLEOMORPHIC LIPOMA A: Spindle cell lipoma consists of bland s...
Book Chapter
Jaw
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-5
ISBN: 978-1-933477-61-9
... there is a histologic spectrum, but the microscopic features of malignancy are usually obvious. There is a rare spindle cell variant of AC where the cells undergo epithelial-mesenchymal transition ( fig. 5-15 ) ( 29 ). Prior to the availability of immunohistochemistry, many of these were no doubt misdiagnosed...
Book Chapter
Oral Cavity
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-4
ISBN: 978-1-933477-61-9
..., and not staining for melanocytic, mesenchymal, or lymphoid markers. Occasional tumors resemble the solid variant of adenoid cystic carcinoma or a high-grade neuroendocrine tumor. Treatment and Prognosis. Treatment options are highly variable and depend on many factors, including the size and location...
Book Chapter
Oropharynx
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-2
ISBN: 978-1-933477-61-9
... related to transcriptionally active high-risk HPV, whereas for basaloid SCC, the association is less consistent, with studies showing 75 to 80 percent of tumors to be transcriptionally active high-risk HPV associated. HPV-associated oropharyngeal SCC commonly has mixed variant patterns so that rare tumors...
Book Chapter
Neck
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-7
ISBN: 978-1-933477-61-9
... are ectodermally-derived developmental abnormalities consisting of skin and other ectodermal tissues ( 76 , 95 – 98 ). Teratoid cysts are a rare variant of dermoid cyst containing, in addition to the ectodermal elements, mesodermal and endodermal tissues ( 99 ). General Features. While dermoid cysts...
Book Chapter
Hypopharynx, Larynx, and Trachea
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-6
ISBN: 978-1-933477-61-9
... . Histopathology 2009 ; 54 : 639 - 56 . 83. Thompson LD . Laryngeal dysplasia, squamous cell carcinoma, and variants . Surg Pathol Clin 2017 ; 10 : 15 - 33 . 84. Zidar N , Gale N . Update from the 5th edition of the World Health Organization classification of head and neck...
Book Chapter
Sinonasal Cavity
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-1
ISBN: 978-1-933477-61-9
.... Molecular Genetic Findings. The NGFI-A binding protein 2 (NAB2) fuses with signal transducer and activator of transcription 6 (STAT6) as a result of a paracentric inversion of chromosome 12q. In other anatomic sites, at least 12 fusion gene variants have been reported, with correlation...
Book Chapter
Nasopharynx
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-3
ISBN: 978-1-933477-61-9
... in endemic areas while the rate is approximately 75 percent in the United States ( 44 ). Certain HLA haplotypes and germline variants in the region encoding HMC class I molecules on chromosome 6p21 have been shown to be associated with susceptibility to developing NPC ( 44 – 47 ). Some EBV-negative NPCs...
Book Chapter
Ear and Temporal Bone
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-8
ISBN: 978-1-933477-61-9
... or epigenetic changes seen in nearly all tumors. Germline pathogenic variants are seen in up to 85 percent of patients tested ( 900 ), with neurofibromatosis, von Hippel-Lindau, and pheochromocytoma-paraganglioma syndromes the most commonly identified syndromes ( 901 – 906 ). Jugulotympanic paragangliomas have...
Images
ADRENAL CORTICAL CARCINOMA: ONCOCYTIC VARIANT Large eosinophilic cells wit...
Available to PurchasePublished: 01 December 2024
ADRENAL CORTICAL CARCINOMA: ONCOCYTIC VARIANT Figure 6-24 ADRENAL CORTICAL CARCINOMA: ONCOCYTIC VARIANT Large eosinophilic cells with abundant granular cytoplasm (A) and nuclear atypia with prominent nucleoli (B) are characteristic of this variant. More about this image found in ADRENAL CORTICAL CARCINOMA: ONCOCYTIC VARIANT Large eosinophilic cells wit...
Images
ADRENAL CORTICAL CARCINOMA: ONCOCYTIC VARIANT Intratumoral lymphocytes are...
Available to PurchasePublished: 01 December 2024
ADRENAL CORTICAL CARCINOMA: ONCOCYTIC VARIANT Figure 6-25 ADRENAL CORTICAL CARCINOMA: ONCOCYTIC VARIANT Intratumoral lymphocytes are frequently seen. More about this image found in ADRENAL CORTICAL CARCINOMA: ONCOCYTIC VARIANT Intratumoral lymphocytes are...
Images
ADRENAL CORTICAL CARCINOMA: MYXOID VARIANT A–C: Myxoid stromal changes are...
Available to PurchasePublished: 01 December 2024
ADRENAL CORTICAL CARCINOMA: MYXOID VARIANT Figure 6-26 ADRENAL CORTICAL CARCINOMA: MYXOID VARIANT A–C: Myxoid stromal changes are variably in extent and distribution. Neoplastic cells are usually small, grow in cords or thin trabeculae, and have less pronounced cytologic atypia. More about this image found in ADRENAL CORTICAL CARCINOMA: MYXOID VARIANT A–C: Myxoid stromal changes are...
Images
ADRENAL CORTICAL CARCINOMA: SARCOMATOID VARIANT This tumor is well-circums...
Available to PurchasePublished: 01 December 2024
ADRENAL CORTICAL CARCINOMA: SARCOMATOID VARIANT Figure 6-27 ADRENAL CORTICAL CARCINOMA: SARCOMATOID VARIANT This tumor is well-circumscribed within the adrenal (A). It has a pure storiform architectural pattern (B) and consists of spindle cells (B) expressing SF1 (C) and Melan-A (D). More about this image found in ADRENAL CORTICAL CARCINOMA: SARCOMATOID VARIANT This tumor is well-circums...
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