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Figure 9-18
Published: 01 December 2024
URINARY BLADDER PARAGANGLIOMA Figure 9-18 URINARY BLADDER PARAGANGLIOMA This paraganglioma shows extensive superficial growth beneath the mucosa. The tumor is a potential mimic of urothelial carcinoma because of its growth pattern and pale eosinophilic to clear cytoplasm. More about this image found in URINARY BLADDER PARAGANGLIOMA This paraganglioma shows extensive superfici...
Images
Figure 9-35
Published: 01 December 2024
URINARY BLADDER PARAGANGLIOMA Figure 9-35 URINARY BLADDER PARAGANGLIOMA A: This extensively invasive urinary bladder paraganglioma deep within the bladder wall is a potential mimic of prostatic or urothelial carcinoma. B: Diffuse expression of tyrosine hydroxylase confirms the identity More about this image found in URINARY BLADDER PARAGANGLIOMA A: This extensively invasive urinary bladder...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-09
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... the differential diagnosis is between a normal paraganglion and an epithelial tumor deposit. This is a concern in the genitourinary tract where normal paraganglia may be mistaken for prostatic ( 13 ) or urothelial cancer because of their often clear cytoplasm (see fig. 9-6 ). PARAGANGLIOMAS Paragangliomas...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-07
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
..., leukemias, choroid plexus tumor Lynch syndrome MSH2, MLH1, PMS2, MSH6, EPCAM Carcinoma 3% (adults) Colorectal, endometrial, small bowel, urothelial, pancreatic, prostatic, sebaceous carcinomas Neurofibromatosis type 1 NF1 Carcinoma (in children) <1% Gliomas, malignant...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-09
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., are a known mimic of urothelial malignancy ( fig. 9-46 ). Although BKV viral cytopathic changes predominantly affect the tubular epithelium, they can also be seen in the Bowman capsule. The late region of HPV has the ORF for two genes, L1 and L2, which encode for a major, highly conserved capsid protein...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-12
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
...   1996 ; 98 ( Pt 1 ): 774 - 8 . 98. Larsen   BT , Smith   ML , Grys   TE , Vikram   HR , Colby   TV . Histopathology of disseminated Mycobacterium bovis infection complicating intravesical BCG immunotherapy for urothelial carcinoma . Int J Surg Pathol   2015 ; 23 : 189 - 95...
Images
Figure 52-2
Published: 15 November 2023
METASTASIS BY RETROGRADE LYMPHATIC SPREAD Figure 52-2 METASTASIS BY RETROGRADE LYMPHATIC SPREAD Left: Metastatic high-grade urothelial carcinoma forms a microscopic metastasis that cannot be seen grossly, but the intense fibrinous pericarditis is a direct consequence of the lymphatic involvement More about this image found in METASTASIS BY RETROGRADE LYMPHATIC SPREAD Left: Metastatic high-grade urot...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-08
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... regulation of RAS IBC, NST (also invasive lobular) CNS Lynch syndrome Various DNA mismatch repair More likely grade 3 TIL rich Low PR ER positive and triple negative reported Gyn GI/hepatobilliary Urothelial a Adapted from reference 28 . b IBC = invasive breast carcinoma; NST...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch23
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
...Table 23-1 IMMUNE CHECKPOINT INHIBITORS a Inhibitor Target Malignancies Ipilimumab CTLA-4 Melanoma, renal cell carcinoma Nivolumab PD-1 Melanoma, non-small cell lung cancer, renal cell carcinoma, urothelial carcinoma, colorectal carcinoma Pembrolizumab PD-1...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch50
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... . Inflammatory myofibroblastic tumors of the urinary tract: a clinicopathologic study of 46 cases, including a malignant example inflammatory fibrosarcoma and a subset associated with high-grade urothelial carcinoma . Am J Surg Pathol   2006 ; 30 : 1502 - 12 . 2. de Winkel   N , Becker   K , Vogt...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch52
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... of the lung (primary tumor, white arrow) has invaded the structures of the superior mediastinum (black asterisk) and is directly invading the wall of the trachea. METASTASIS BY RETROGRADE LYMPHATIC SPREAD Figure 52-2 METASTASIS BY RETROGRADE LYMPHATIC SPREAD Left: Metastatic high-grade urothelial carcinoma...
Images
Figure 9-13
Published: 01 August 2023
OVARIAN SURFACE IMPLANTATION OF HIGH-GRADE UROTHELIAL CARCINOMA Figure 9-13 OVARIAN SURFACE IMPLANTATION OF HIGH-GRADE UROTHELIAL CARCINOMA The patient had an ipsilateral high-grade noninvasive urothelial carcinoma of ureter. No Brenner components are present. More about this image found in OVARIAN SURFACE IMPLANTATION OF HIGH-GRADE UROTHELIAL CARCINOMA The patien...
Images
Figure 9-9
Published: 01 August 2023
BORDERLINE BRENNER TUMOR Figure 9-9 BORDERLINE BRENNER TUMOR Blunt intracystic papillae (A,B) and bland nuclear features with maturation from base to lumen (B,C) are seen. These features are similar to noninvasive low-grade papillary urothelial carcinoma or urothelial papillary neoplasm of low More about this image found in BORDERLINE BRENNER TUMOR Blunt intracystic papillae (A,B) and bland nuclea...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-09
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
...Transitional cell tumors of the ovary resemble urothelial neoplasms of the urinary tract. Broad undulating papillae containing cells with severe nuclear atypia are considered reminiscent of high-grade urothelial carcinomas, whereas papillary tumors containing stratified cells with nuclear...
Images
Figure 5-6
Published: 01 August 2023
TRANSITIONAL-LIKE AND MICROCYSTIC ARCHITECTURE Figure 5-6 TRANSITIONAL-LIKE AND MICROCYSTIC ARCHITECTURE Broad papillae resembling those of urothelial carcinoma (“transitional-like) (A–C) often coexists with microcystic pattern (D,E). More about this image found in TRANSITIONAL-LIKE AND MICROCYSTIC ARCHITECTURE Broad papillae resembling t...
Images
Figure 9-10
Published: 01 August 2023
is identified. The appearance is similar to noninvasive high-grade papillary urothelial carcinoma and is considered borderline Brenner tumor with intraepithelial carcinoma. C: Microinvasion is represented at right by nests of neoplastic cells surrounded by clefted spaces. More about this image found in BORDERLINE BRENNER TUMOR WITH INTRAEPITHELIAL CARCINOMA AND MICROINVASION ...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-05
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... is common in high-grade serous carcinoma and should not lead to a diagnosis of a mixed carcinoma with an undifferentiated component. TRANSITIONAL-LIKE AND MICROCYSTIC ARCHITECTURE Figure 5-6 TRANSITIONAL-LIKE AND MICROCYSTIC ARCHITECTURE Broad papillae resembling those of urothelial carcinoma...
Images
Figure 5-48
Published: 01 February 2023
SECONDARY PAGET DISEASE OF UROTHELIAL ORIGIN Figure 5-48 SECONDARY PAGET DISEASE OF UROTHELIAL ORIGIN The presence of acantholysis and clefting between malignant cells and squamous epithelium is more often seen with spread of a urothelial primary (left). Nonetheless, the lesion may bear close More about this image found in SECONDARY PAGET DISEASE OF UROTHELIAL ORIGIN The presence of acantholysis ...
Images
Figure 3-77
Published: 01 February 2023
UROTHELIAL CARCINOMA METASTATIC TO THE CERVIX Figure 3-77 UROTHELIAL CARCINOMA METASTATIC TO THE CERVIX Left: In this case, spread occurred in a pagetoid fashion, and was initially interpreted as an HSIL of the cervix. Right: The primary lesion in the bladder, depicted here, shows identical More about this image found in UROTHELIAL CARCINOMA METASTATIC TO THE CERVIX Left: In this case, spread o...
Images
Figure 3-24
Published: 01 February 2023
PAPILLARY SQUAMOTRANSITIONAL CARCINOMA Figure 3-24 PAPILLARY SQUAMOTRANSITIONAL CARCINOMA Filiform papillae lined by a cellular stratified proliferation without overt squamous maturation mimic urothelial differentiation. More about this image found in PAPILLARY SQUAMOTRANSITIONAL CARCINOMA Filiform papillae lined by a cellul...