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Figure 9-35
Published: 01 December 2024
URINARY BLADDER PARAGANGLIOMA Figure 9-35 URINARY BLADDER PARAGANGLIOMA A: This extensively invasive urinary bladder paraganglioma deep within the bladder wall is a potential mimic of prostatic or urothelial carcinoma. B: Diffuse expression of tyrosine hydroxylase confirms the identity More about this image found in URINARY BLADDER PARAGANGLIOMA A: This extensively invasive urinary bladder...
Images
Figure 9-6
Published: 01 December 2024
NORMAL PARAGANGLION IN THE WALL OF ADULT URINARY BLADDER Figure 9-6 NORMAL PARAGANGLION IN THE WALL OF ADULT URINARY BLADDER Incidentally discovered paraganglia can be mistaken for deposits of prostatic, renal cell, or other carcinomas. As in this example, their identity can be further obscured More about this image found in NORMAL PARAGANGLION IN THE WALL OF ADULT URINARY BLADDER Incidentally disc...
Images
Figure 9-18
Published: 01 December 2024
URINARY BLADDER PARAGANGLIOMA Figure 9-18 URINARY BLADDER PARAGANGLIOMA This paraganglioma shows extensive superficial growth beneath the mucosa. The tumor is a potential mimic of urothelial carcinoma because of its growth pattern and pale eosinophilic to clear cytoplasm. More about this image found in URINARY BLADDER PARAGANGLIOMA This paraganglioma shows extensive superfici...
Images
Figure 9-22
Published: 01 December 2024
URINARY BLADDER PARAGANGLIOMA Figure 9-22 URINARY BLADDER PARAGANGLIOMA A: This paraganglioma extends between muscle bundles in the bladder wall and is a potential mimic of other more aggressive neoplasms because of its growth pattern. B: Higher magnification of the tumor shows that most More about this image found in URINARY BLADDER PARAGANGLIOMA A: This paraganglioma extends between muscle...
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Figure 11-5
Published: 01 December 2024
ultrasound was suspicious of a renal tumor. After referral to an expert center, clinical examination (slight hypertension), laboratory testing (increased urinary catecholamines), and abdominal MRI imaging showed that a diagnosis of metastatic NB was more likely. The MRI depicted a right-sided adrenal mass More about this image found in METAIODOBENZYLGUANIDINE (MIBG) SCAN OF WIDELY METASTASIZED NEUROBLASTOMA A...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-09
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
.... The TH stain also emphasizes the trabecular architecture. NORMAL PARAGANGLION IN THE WALL OF ADULT URINARY BLADDER Figure 9-6 NORMAL PARAGANGLION IN THE WALL OF ADULT URINARY BLADDER Incidentally discovered paraganglia can be mistaken for deposits of prostatic, renal cell, or other carcinomas...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-03
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... cortisol can also be used to screen for this disorder ( 5 ). Ultimately, hypercortisolism is established by measuring the 24h-hour urinary free cortisol, which is an integrated measure. Cortisol is regulated by ACTH, and in primary adrenal disease, the elevated cortisol levels are usually associated...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-08
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... exists. Biochemistry and Signaling Pathways Biochemical testing to assess catecholamine production, as discussed in chapter 1 , is the first and most definitive way of confirming the diagnosis of pheochromocytoma ( 13 ). The current technologies have moved to measurement of plasma and urinary free...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-06
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... in the excessive secretion of a range of steroid hormone precursors, instead of the end products of steroid hormone biosynthesis; the precursors can be quantified using mass spectrometry-based urinary steroid metabolite profiling of 24-hour urine samples ( 69 – 75 ). A seminal paper retrospectively compared 45...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-04
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
...-hydroxycorticosteroid and urinary free cortisol levels (so-called Liddle test), a feature that distinguishes PPNAD from Cushing syndrome caused by other primary adrenal disorders ( 35 ). CT images with slice thickness of 5 or 10 mm obtained in patients with both PPNAD (and i-MAD) underestimate the presence...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-11
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
...), laboratory testing (increased urinary catecholamines), and abdominal MRI imaging showed that a diagnosis of metastatic NB was more likely. The MRI depicted a right-sided adrenal mass with retroperitoneal lymph node metastases. Additional MIBG scintigraphy shows increased uptake in the primary adrenal NB...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-22
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... is of particular value in disseminated disease, which is frequently associated with renal involvement and urinary shedding of spores. Organisms are also identified by direct microscopic examination of conjunctival and nasal scrapings, biliary fluid, endoscopic touch preparations, histology of intestinal/other...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-20
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... ). Dissemination to the urinary tract, especially the prostate gland, may be asymptomatic or associated with symptoms of prostatitis and obstruction ( 9 ). Eye manifestations include ocular muscle palsy (due to cranial nerve involvement), papilledema (secondary to raised intracranial pressure with CNS disease...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-09
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
...-creatinine, hematuria, and fever. In this population, viruria is followed by viremia in 10 to 15 percent of patients. Persistent viremia is associated with interstitial nephritis, which may lead to subsequent transplant failure in 50 to 80 percent of cases. Other urinary tract presentations include...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-13
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
.../near normal mucosa with epithelial disarray and degeneration ExPEC Clinical features as for other bacteremias and bacterial causes of infection of urinary tract, meninges, and other sites Prominent neutrophilic response, with acute suppurative features, tissue necrosis, and frequent abscess...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-12
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... disease. Detection of urinary lipoarabinomannan (a M. tuberculosis byproduct) has been useful in individuals with HIV and CD4 cell counts over 200/μL. The histologic differential diagnosis of tuberculosis in all its stages includes most of the dimorphic fungi, as well as nontuberculous...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-26
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
.... This organism causes intestinal disease that can mimic amebiasis, but is also associated with rare respiratory and urinary tract involvement. B. coli is the largest protozoan to infect humans and is distinguished from E. histolytica by its significantly larger size (ranging from 30 to 150 μm...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-04
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... of disease varies from asymptomatic to disseminated infection, with severe respiratory symptoms due to a viral pneumonitis and involvement of numerous other organ systems, including the liver, CNS, urinary tract, and GI tract. Lung infection typically shows patchy, bilateral ground glass opacities on chest X...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-21
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... change ( fig. 21-2 ). Bone lesions are usually lytic and associated with pain, draining sinuses, and surrounding erythema. The prostate gland is the most common urinary tract site involved. Immunocompromised individuals, including those receiving a tumor necrosis factor-alpha (TNFα) inhibitor...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch50
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... . Inflammatory myofibroblastic tumors of the urinary tract: a clinicopathologic study of 46 cases, including a malignant example inflammatory fibrosarcoma and a subset associated with high-grade urothelial carcinoma . Am J Surg Pathol   2006 ; 30 : 1502 - 12 . 2. de Winkel   N , Becker   K , Vogt...