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Images
Published: 01 September 2024
ERYTHEMA NODOSUM LEPROSUM Figure 15-16 ERYTHEMA NODOSUM LEPROSUM Also known as type 2 leprosy reaction, there are new and painful, nodular skin lesions in an individual with lepromatous leprosy. (Courtesy of the CDC PHIL) More about this image found in ERYTHEMA NODOSUM LEPROSUM Also known as type 2 leprosy reaction, there are...
Images
Published: 01 September 2024
POST-TRANSPLANT EBV-ASSOCIATED LYMPHOPROLIFERATIVE DISEASE (PTLD) OF THE MONOMORPHIC TYPE Figure 8-14 POST-TRANSPLANT EBV-ASSOCIATED LYMPHOPROLIFERATIVE DISEASE (PTLD) OF THE MONOMORPHIC TYPE Low-power view (A) plasmacytoma-like features (B) and positivity for EBER ISH (C). (Courtesy of Dr. S. As... More about this image found in POST-TRANSPLANT EBV-ASSOCIATED LYMPHOPROLIFERATIVE DISEASE (PTLD) OF THE MO...
Images
Published: 01 September 2024
PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY Figure 3-40 PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY Infected oligodendrocytes also show nuclear p53 immunostaining, a feature shared with several types of glial tumors. More about this image found in PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY Infected oligodendrocytes also ...
Images
Published: 01 September 2024
TUBERCULOUS GRANULOMA Figure 12-54 TUBERCULOUS GRANULOMA Low power shows extensive circumscribed central fibrillogranular necrosis (A). Some scattered peripheral multinucleated giant cells show a typical Langhans-type morphology (B). More about this image found in TUBERCULOUS GRANULOMA Low power shows extensive circumscribed central fibr...
Images
Published: 01 September 2024
PULMONARY COCCIDIOIDOMYCOSIS Figure 21-8 PULMONARY COCCIDIOIDOMYCOSIS Confluent well-formed granulomatous foci have prominent foreign body-type multinucleated giant cells (A), and prominent necrosis with secondary cavitation (B). (Courtesy of the CDC PHIL) More about this image found in PULMONARY COCCIDIOIDOMYCOSIS Confluent well-formed granulomatous foci have...
Images
Published: 01 September 2024
JC VIRUS GRANULE CELL NEURONOPATHY Figure 3-43 JC VIRUS GRANULE CELL NEURONOPATHY Coronal T1-weighted MRI scan shows less frequent type of PML, JC virus granule cell neuronopathy. Note the severe damage to the cerebellar hemisphere (lower right of the image). More about this image found in JC VIRUS GRANULE CELL NEURONOPATHY Coronal T1-weighted MRI scan shows less...
Images
Published: 01 September 2024
WHIPPLE DISEASE Figure 13-36 WHIPPLE DISEASE A–C: Endoscopic small intestinal biopsy shows shortened broad villi distended by a striking foamy macrophage infiltrate. D: High-power view demonstrates numerous lamina propria macrophages with scattered intervening plasma cells and eosinophils. These... More about this image found in WHIPPLE DISEASE A–C: Endoscopic small intestinal biopsy shows shortened br...
Images
Published: 01 September 2024
PULMONARY COVID-19 Figure 4-10 PULMONARY COVID-19 A: Initial changes show some intra-alveolar fibrin with focal early hyaline membrane formation, scattered intra-alveolar red blood cells, and focal mild interstitial lymphocyte infiltration. B: Low-power view of patchy intra-alveolar fibrin with ... More about this image found in PULMONARY COVID-19 A: Initial changes show some intra-alveolar fibrin with...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-07
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... to one quarter of patients with SARS-CoV-2 infection, and can occur with vaccination ( 4 ). Bacteria, fungi, and protozoa also cause infectious myocarditis, as highlighted in Table 7-1 . Table 7-1 SELECTED CAUSES OF INFECTIOUS AND NONINFECTIOUS MYOCARDITIS Type Etiology Known Causes...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-17
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... are divided into type A (the tularensis subspecies present in North America) and type B. Type A is considered one of the most infectious micro-organisms known since fewer than 10 bacteria are capable of causing disease; type B requires a considerably higher organism dose (more than 103...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-15
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... threatening (such as necrotizing fasciitis). Table 15-1 presents the different types of skin and soft tissue infections, their characteristics, and the causative organisms. Infections that produce necrosis can occur in any skin or soft tissue layer, and their rapid progression and deadly consequence were...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-04
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... influenza B exclusively affects humans and seals. Influenza viruses are further subdivided by their surface hemagglutinin (H) and neuraminidase (N) protein antigens. According to international convention on influenza virus nomenclature, antigenic type (most frequently A or B) is specified first, followed...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-23
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... immunodeficiency virus (HIV) infection or an organ transplant. In the environment, Histoplasma spp are found as a mold, and mycelia produce two types of conidia: macroconidia and microconidia. As the microconidia are small and light, they can be inhaled and easily reach the terminal airways and alveoli...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-08
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., each associated with the production of various viral proteins and particular types of neoplasia ( Table 8-1 ). EBNA2 and LMP1 are the proteins responsible for the transformation of lymphocytes and give rise to the virus’s oncogenic potential. LMP1 induces DNA synthesis and production of cytokines (IL-6...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-09
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... to be two types of HIV: human immunodeficiency viruses 1 and 2 (HIV1, HIV2). HIV1 is the predominant type and has a worldwide distribution; HIV2 appears to be a less-infectious subtype and is mainly limited to West Africa. These viruses emerged in man independently, transferring from primate viruses over...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-03
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... days. Sometimes, the same individual alternates between the two types of clinical disease. Other clinical presentations include tetanus-like symptoms, neuromyelitis optica, and transverse myelitis. Magnetic resonance imaging (MRI) can be useful in diagnosis, particularly when differentiating...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-28
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., amount of sandfly saliva, and the host immune response. LIFE CYCLE OF LEISHMANIA SPP Figure 28-1 LIFE CYCLE OF LEISHMANIA SPP The spectrum of clinical and pathologic manifestations are largely determined by the nature of the immune reaction. Type 2 T-helper cell predominance...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-02
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... to a cadaveric corneal transplant Variable incubation period of up to 42 years, depending on the type of intervention, thus sometimes making it difficult to attribute the case to a particular transmission event Approximately 1% of all CJD cases Sporadic CJD Onset between 60 and 69 years Annual...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-01
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., and molecular pathologists. Although many pathology practices have segregated into subspecialties based on specimen type and specific case volume, the pathology of infectious diseases interfaces with virtually every other subdiscipline of pathology. The diverse nature and intertwining complexity of this field...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-21
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... body-type giant cells, although not easily appreciated with a routine hematoxylin and eosin (H&E) stain. If visualized, a refractile cell wall and several yeast nuclei are clues to the presence of the yeasts. The use of special stains for fungi, including silver-based GMS and periodic acid-Schiff...
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