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in Congenital Disorders of the Adrenal Gland
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
is the cyst lumen. B: Recognition of the fascicular arrangement of cytologically bland adrenal cells in frozen section allowed the transplant to proceed. C: The diagnosis was confirmed by immunohistochemical staining for inhibin. More about this image found in ADRENAL CORTICAL TISSUE IN A DONOR KIDNEY BIOPSY A: Uncircumscribed adrena...
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Published: 01 September 2024
POST-TRANSPLANT EBV-ASSOCIATED LYMPHOPROLIFERATIVE DISEASE (PTLD) OF THE MONOMORPHIC TYPE Figure 8-14 POST-TRANSPLANT EBV-ASSOCIATED LYMPHOPROLIFERATIVE DISEASE (PTLD) OF THE MONOMORPHIC TYPE Low-power view (A) plasmacytoma-like features (B) and positivity for EBER ISH (C). (Courtesy of Dr. S More about this image found in POST-TRANSPLANT EBV-ASSOCIATED LYMPHOPROLIFERATIVE DISEASE (PTLD) OF THE MO...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-02
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
..., or assessment of donor organs for transplantation. In other situations, an underlying genetic disorder affecting hormone synthesis may alter adrenal anatomy or a functional tumor may arise in ectopic or malformed adrenal tissue. ADRENAL ADHESION, UNION, AND FUSION Adrenal adhesion and adrenal...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-11
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... on chemotherapy, followed by cytoreductive (debulking) surgery, and myeloablative chemotherapy with autologous stem cell transplantation ( 84 ). Further treatment options have become available through the use of 131I-metaiodobenzylguanidine for targeted radiotherapy in relapsed and refractory patients...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-08
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
...), with EBV-encoded small RNA (EBER) Highly immunogenic, triggering a strong T-cell response In immune suppressed individuals: post-transplant lymphoproliferative disorder (PTLD), diffuse large B-cell lymphoma II EBNA1 and LMP1, 2, with EBERs Intermediate between latency type III and I EBV-positive...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-09
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... PATIENT POPULATIONS Disease Frequency BK virus BKN nephropathy 1-10% of renal transplants Ureteral stenosis 3% of renal transplants Hemorrhagic cystitis 10-25% of bone marrow transplants JC virus Progressive multifocal leukoencephalopathy 5% of untreated AIDS patients...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-29
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... in congenital infections (when serology is unreliable due to the presence of maternal antibodies), suspected reactivation of Chagas disease in the immunocompromised, organ transplant recipients who have received organs from infected donors, and for the diagnosis of infections acquired by T. cruzi...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-25
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... immunosuppressed patients, such as those with organ transplants. Although the number of reported cases is low, the frequency of disease is likely higher since the expertise for detection of these protozoans is not available in many communities and countries ( 25 ). These amebae have two morphologic stages...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-02
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... to a cadaveric corneal transplant Variable incubation period of up to 42 years, depending on the type of intervention, thus sometimes making it difficult to attribute the case to a particular transmission event Approximately 1% of all CJD cases Sporadic CJD Onset between 60 and 69 years Annual...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-20
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... disease). Immune-compromised individuals who are treated by alleviating their immunosuppression (e.g., commencement of antiretroviral therapy in a patient with acquired immunodeficiency syndrome [AIDS] or reduced immunosuppressive treatment in an organ transplant recipient) are at risk for developing...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-21
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., hematologic malignancies, and transplants; sources include disruption of skin or a mucosal lining; presentation includes fever unresponsive to antibiotics, myalgia, and painful papular skin lesions that progress to eschars; can lead to secondary septic arthritis, osteomyelitis, pneumonia, and brain abscess...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-22
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... known to be relatively common pathogens in the immune competent, causing an asymptomatic or self-limited enteric infection and travelers diarrhea ( 25 ). Immunocompromised patients, most often those with AIDS and solid organ (especially kidney) as well as bone marrow transplants, are prone to develop...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-12
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... NH . Bordetella pertussis: new concepts in pathogenesis and treatment . Curr Opin Infect Dis 2016 ; 29 : 287 - 94 . 41. Restrepo A , Clark NM , Infectious Diseases Community of Practice of the American Society of Transplantation . Nocardia infections in solid organ...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-01
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... . Illustrative Case: A 47-year-old man presents with declining renal function 9 months post-renal transplant. A renal core biopsy demonstrates chronic tubulointerstitial nephritis with tubular atrophy, early interstitial fibrosis, and focally atypical renal tubular epithelial cells ( fig. 1-9A–C ). The latter...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-19
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... and can infect other immunocompromised individuals, including those with an underlying malignancy, autoimmune disease, and organ transplant. Disease due to this fungus was originally called penicilliosis (the organism was initially classified as Penicillium marneffei), but is now more correctly...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-24
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
.... Ahmed J , Ditmars DM , Sheppard T , del Busto R , Venkat KK , Parasuraman R . Recurrence of Scedosporium apiospermum infection following renal re-transplantation . Am J Transplant 2004 ; 4 : 1720 - 4 . 28. Werlinger KD , Yen Moore A . Eumycotic mycetoma...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-27
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... negative Hyposplenism Glucose-6-phosphate dehydrogenase (G6PD) deficiency a HIV = human immunodeficiency virus. Table 27-3 RISK FACTORS FOR SEVERE BABESIOSIS Neonates and age >50 years Chronic heart, lung and liver disease Asplenism Organ transplant patients Underlying...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-03
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... spp (possibly ticks) Birds Worldwide Disease can be acquired through mosquito bites, blood transfusions, organ transplants, breast milk, and transplacentally Japanese encephalitis JEV Aedes, Anopheles and Culex spp Birds Asia, Australia, and Eastern Pacific Cyclical major...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-07
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... activity should be avoided and the use of immunosuppressive drugs and immune modulators (including interferon) is currently controversial ( 11 ). In cases of severe heart failure, extracorporeal membrane oxygenation (ECMO) or a ventricular assist device (VAD) may be required. Cardiac transplant remains...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-23
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... immunodeficiency virus (HIV) infection or an organ transplant. In the environment, Histoplasma spp are found as a mold, and mycelia produce two types of conidia: macroconidia and microconidia. As the microconidia are small and light, they can be inhaled and easily reach the terminal airways and alveoli...
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