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Images
Figure 7-25
Published: 01 June 2025
THYROGLOSSAL DUCT CYST WITH PAPILLARY THYROID CARCINOMA Figure 7-25 THYROGLOSSAL DUCT CYST WITH PAPILLARY THYROID CARCINOMA A: This thyroglossal duct cyst has papillary thyroid carcinoma arising within it, with edematous papillae and inconspicuous tumor cells lining them. The hyoid bone is seen More about this image found in THYROGLOSSAL DUCT CYST WITH PAPILLARY THYROID CARCINOMA A: This thyrogloss...
Images
Figure 7-31
Published: 01 June 2025
METASTATIC PAPILLARY THYROID CARCINOMA Figure 7-31 METASTATIC PAPILLARY THYROID CARCINOMA A: The lymph node shows extensive cystic change at low-power magnification. The cystic spaces vary from being empty to filled with densely eosinophilic colloid material or hemorrhage, with scattered More about this image found in METASTATIC PAPILLARY THYROID CARCINOMA A: The lymph node shows extensive c...
Images
Figure 7-35
Published: 01 June 2025
METASTATIC PAPILLARY THYROID CARCINOMA Figure 7-35 METASTATIC PAPILLARY THYROID CARCINOMA The aspirate contains crowded cells with moderate amounts of cytoplasm, oval nuclei with fine, evenly distributed chromatin, and prominent grooves in a background with debris. (Papanicolaou stain) More about this image found in METASTATIC PAPILLARY THYROID CARCINOMA The aspirate contains crowded cells...
Images
Figure 7-36
Published: 01 June 2025
METASTATIC NONPAPILLARY THYROID CARCINOMA TO LEVELS V, VI, AND VII Figure 7-36 METASTATIC NONPAPILLARY THYROID CARCINOMA TO LEVELS V, VI, AND VII Metastatic anaplastic thyroid carcinoma (A), and metastatic medullary thyroid carcinoma (B). (Papanicolaou stains) More about this image found in METASTATIC NONPAPILLARY THYROID CARCINOMA TO LEVELS V, VI, AND VII Metasta...
Images
Figure 7-23
Published: 01 June 2025
THYROGLOSSAL DUCT CYST Figure 7-23 THYROGLOSSAL DUCT CYST A: On low power, this thyroglossal duct cyst is almost unilocular, with a thin lining, fibrous wall, and some residual thyroid tissue in the upper right corner. B: This thyroglossal duct cyst has a mixture of respiratory and squamous More about this image found in THYROGLOSSAL DUCT CYST A: On low power, this thyroglossal duct cyst is alm...
Images
Figure 7-24
Published: 01 June 2025
THYROGLOSSAL DUCT CYST Figure 7-24 THYROGLOSSAL DUCT CYST This cyst is noninflamed, lined by respiratory epithelium, and has scattered thyroid follicles in the wall. More about this image found in THYROGLOSSAL DUCT CYST This cyst is noninflamed, lined by respiratory epit...
Images
Figure 3-14
Published: 01 June 2025
LOW-GRADE NASOPHARYNGEAL PAPILLARY ADENOCARCINOMA Figure 3-14 LOW-GRADE NASOPHARYNGEAL PAPILLARY ADENOCARCINOMA A–C: Papillary arrangement of crowded, elongated to cuboidal tumor cells mimics papillary thyroid carcinoma. D: There is a loose central fibrovascular core. E: Nuclei are oval More about this image found in LOW-GRADE NASOPHARYNGEAL PAPILLARY ADENOCARCINOMA A–C: Papillary arrangeme...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-7
ISBN: 978-1-933477-61-9
... glands, and thyroid C cells. The arches are each a mixture of mesoderm, ectoderm, and endoderm and most of the developmental abnormalities of the head and neck derive from remnants of the branchial apparatus that fail to disappear normally as these structures develop ( 2 , 3 , 5 ). Examples...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-3
ISBN: 978-1-933477-61-9
...-derived carcinoma with low-grade features. LGNPA was previously known as and classified by the World Health Organization (WHO) as “thyroid-like low-grade nasopharyngeal papillary adenocarcinoma” owing to its histomorphologic similarity and partial immunophenotypic overlap with papillary thyroid carcinoma...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-6
ISBN: 978-1-933477-61-9
..., thyroid cartilage, anterior arch of the cricoid cartilage, thyrohyoid membrane, and cricothyroid membrane ( 1 , 4 , 5 ). Posteriorly, the larynx is bordered by the posterior portion of the cricoid cartilage and the arytenoid region. ANATOMY OF THE LARYNX Figure 6-2 ANATOMY OF THE LARYNX A,B...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-8
ISBN: 978-1-933477-61-9
... cardiovascular disease, hypertension, diabetes mellitus, lupus erythematosus, granuloma annulare, rheumatoid arthritis, scleroderma, Raynaud syndrome, Hashimoto thyroiditis, and other autoimmune and connective tissue disorders ( 61 , 62 , 65 ). While skin tumors are more common, CNCH is a fairly common external...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-4
ISBN: 978-1-933477-61-9
... ) ( 238 ). The solid tumor islands show clefting from the surrounding dense fibrous stroma. The tumor cells of CASG are monomorphically similar to PAC but show pale to eosinophilic cytoplasm, with overlapping nuclei with delicate vesicular to open chromatin, mimicking papillary thyroid carcinoma ( fig. 4...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-1
ISBN: 978-1-933477-61-9
... adenoma (pituitary neuroendocrine tumor), either ectopic or arising secondarily from the pituitary gland ( 172 , 173 ). Immunostains for pituitary transcription factors (e.g., Pit-1, T-pit, SF-1) and/or pituitary hormones (prolactin, growth hormone, adrenocorticotrophic hormone, thyroid-stimulating...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-2
ISBN: 978-1-933477-61-9
... , 115 , 117 , 118 ). Secretory Carcinoma Secretory carcinoma is a unique and fairly recently described salivary gland tumor that has an analogue in the breast, as the former name “mammary analogue secretory carcinoma” suggests, but also in the skin and thyroid gland. Almost all tumors have...
Images
Images
Figure 9-10
Published: 01 December 2024
NORMAL PERITHYROIDAL PARAGANGLION Figure 9-10 NORMAL PERITHYROIDAL PARAGANGLION A: This paraganglion, discovered incidentally in peri-thyroidal soft tissue in an adult patient with a multinodular goiter, is architecturally similar to the carotid body in figure 9-7 . The intimate association More about this image found in NORMAL PERITHYROIDAL PARAGANGLION A: This paraganglion, discovered inciden...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-09
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
.... Other microscopic paraganglia are distributed in the floor and wall of the middle ear (jugulotympanic paraganglia), in or near the nodose ganglion of the vagus nerve (vagal paraganglia), or near the thyroid gland or larynx in association with the terminus of the superior laryngeal...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-10
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... Locations Cluster Other Associated Lesions RET 10q11.2 MEN2 (multiple endocrine neoplasia type 2) Adrenal 2 Medullary thyroid carcinoma; parathyroid hyperplasia or neoplasia Mucocutaneous ganglioneuromas (MEN2B) NF1 17q11.2 NF1 (neurofibromatosis type 1) Adrenal (rarely...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-07
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... disease PDE11A, PDE8B, PRKACA Isolated micronodular adrenal disease <1% — Carney complex and isolated familial PPNAD PRKAR1A (PDE11A, PDE8B rare) PPNAD (carcinoma in case reports) <1% Pituitary and thyroid tumors, cardiac myxomas, peripheral nerve sheath tumors...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-02
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... which defy logical embryologic explanation, e.g., placenta ( 7 ), lung ( 8 ), pituitary gland ( 9 , 10 ), and intracranially ( 11 ). Rare reverse examples of other types of tissues located heterotopically within the adrenal have also been reported. These include intra-adrenal hepatic ( 12 ) and thyroid...