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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 11
Publisher: American Registry of Pathology
Published: 01 June 2022
DOI:
10.55418/9781933477190-3
ISBN-10: 1-933477-19-9
ISBN: 978-1-933477-19-0
... 8; CEA = carcinoembryonic antigen; TTF-1 = thyroid transcription factor-1. Table 3-5 IMMUNOHISTOCHEMICAL MARKERS USED IN THE DIFFERENTIAL DIAGNOSIS OF PLEURAL MESOTHELIOMA VERSUS SQUAMOUS CELL CARCINOMA OF THE LUNG INVOLVING THE PLEURA a Marker Current Value/Comments...
Images
Published: 01 November 2021
THYROID-LIKE FOLLICULAR RENAL CELL CARCINOMA Figure 2-192 THYROID-LIKE FOLLICULAR RENAL CELL CARCINOMA Cysts of variable size are in a solid light brown parenchyma. A partial pseudocapsule is visible. More
Images
Published: 01 November 2021
THYROID-LIKE FOLLICULAR RENAL CELL CARCINOMA Figure 2-193 THYROID-LIKE FOLLICULAR RENAL CELL CARCINOMA This tumor is composed of round follicles varying in size and filled with eosinophilic proteinaceous material resembling thyroid colloid. More
Images
Published: 01 November 2021
THYROID-LIKE FOLLICULAR RENAL CELL CARCINOMA Figure 2-194 THYROID-LIKE FOLLICULAR RENAL CELL CARCINOMA Irregularly shaped branching follicles are filled with colloid-like material. More
Images
Published: 01 November 2021
THYROID-LIKE FOLLICULAR RENAL CELL CARCINOMA Figure 2-195 THYROID-LIKE FOLLICULAR RENAL CELL CARCINOMA Cysts are formed. More
Images
Published: 01 November 2021
THYROID-LIKE FOLLICULAR RENAL CELL CARCINOMA WITH A MICROFOLLICULAR GROWTH PATTERN Figure 2-196 THYROID-LIKE FOLLICULAR RENAL CELL CARCINOMA WITH A MICROFOLLICULAR GROWTH PATTERN Small follicles are filled with colloid-like material. More
Images
Published: 01 November 2021
THYROID-LIKE FOLLICULAR RENAL CELL CARCINOMA Figure 2-197 THYROID-LIKE FOLLICULAR RENAL CELL CARCINOMA This tumor, which some would call an “atrophic kidneylike renal tumor,” is surrounded by a distinct pseudocapsule. The parenchyma of the unfixed tumor is light pink and yellow, and contains cyst... More
Images
Published: 01 November 2021
THYROID-LIKE FOLLICULAR RENAL CELL CARCINOMA Figure 2-198 THYROID-LIKE FOLLICULAR RENAL CELL CARCINOMA Left: The architecture of the follicles in tumors that some call “atrophic kidney-like” is similar to the architecture of thyroid-like follicular renal cell carcinoma, as is the colloid-like pro... More
Images
Published: 01 November 2021
THYROID-LIKE FOLLICULAR RENAL CELL CARCINOMA Figure 2-199 THYROID-LIKE FOLLICULAR RENAL CELL CARCINOMA Left: Some of the calcifications in “atrophic kidney-like” tumors are spherical psammoma bodies composed of multiple layers. Right: Other calcifications are amorphous cloud-like aggregates of s... More
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 10
Publisher: American Registry of Pathology
Published: 01 January 2022
DOI:
10.55418/9781933477183-7
ISBN-10: 1-933477-18-0
ISBN: 978-1-933477-18-3
... syndromes Example: Stouffer syndrome Not uncommon clinically, but rarely biopsied Sepsis Rare in surgical pathology, but common at autopsy Thyroid disease Not uncommon clinically, but rarely biopsied; can be hypothyroid or hyperthyroid disease a FIC = familial intrahepatic cholestasis; BSEP...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 10
Publisher: American Registry of Pathology
Published: 01 January 2022
DOI:
10.55418/9781933477183-13
ISBN-10: 1-933477-18-0
ISBN: 978-1-933477-18-3
... dysregulation, polyendocrinopathy, and enteropathy, X-linked (IPEX) syndrome is a rare X-linked recessive disorder characterized by early onset type I diabetes mellitus, severe enteropathy, eczema, hemolytic anemia, thrombocytopenia and thyroiditis causing hypothyroidism ( 2 ). Demographics...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 10
Publisher: American Registry of Pathology
Published: 01 January 2022
DOI:
10.55418/9781933477183-5
ISBN-10: 1-933477-18-0
ISBN: 978-1-933477-18-3
... diseases are autoimmune thyroiditis, rheumatoid arthritis, Sjogren syndrome, inflammatory bowel disease, and celiac disease. In rare cases (less than 1 percent) there is a family history of autoimmune hepatitis ( 5 ). Environmental factors also clearly play a strong role, but to date, the exposures...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 10
Publisher: American Registry of Pathology
Published: 01 January 2022
DOI:
10.55418/9781933477183-1
ISBN-10: 1-933477-18-0
ISBN: 978-1-933477-18-3
... ABCB11 mutations (PFIC2); mutated protein is called BSEP ABCB4 mutations (PFIC3); mutated protein is called DR3 Sepsis Thyroid disease (mild, not usually biopsied) Hyperthyroid Hypothyroid Table 1-7 ABNORMAL CYTOPLASMIC CHANGES IN HEPATOCYTES Glycogen accumulation...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 10
Publisher: American Registry of Pathology
Published: 01 January 2022
DOI:
10.55418/9781933477183-10
ISBN-10: 1-933477-18-0
ISBN: 978-1-933477-18-3
... organs affected by iron deposition are spleen, heart, and bone marrow ( 34 ). Accumulation of iron in the liver precedes iron deposition in other organs ( 39 ). Other organs affected by iron deposition include acinar epithelium of pancreas, thyroid gland, myocardium, and the submucosal or minor salivary...
Images
Published: 01 October 2021
FOLLICULAR CARCINOMA OF THE THYROID GLAND METASTATIC TO THE HUMERUS Figure 18-40 FOLLICULAR CARCINOMA OF THE THYROID GLAND METASTATIC TO THE HUMERUS The tumor has destroyed the underlying bone and has a nodular tan-yellow appearance. More
Images
Published: 01 October 2021
METASTATIC FOLLICULAR THYROID CARCINOMA Figure 18-48 METASTATIC FOLLICULAR THYROID CARCINOMA The neoplastic cells have abundant eosinophilic cytoplasm. The follicles contain finely granular pink colloid material. More
Images
Published: 01 November 2021
CAPSULAR INVASION Figure 1-128 CAPSULAR INVASION Left: By “horizontal analysis,” neoplastic nephroblastoma cells are at the same level as the perirenal fat (arrow), supporting capsular invasion, which makes the neoplasm stage II. Right: Occasionally capsular invasion may have a “mushroom”-like a... More
Images
Published: 01 October 2021
BROWN TUMOR Figure 18-24 BROWN TUMOR Left: Lateral radiograph of the leg of a patient with hyper thyroidism demonstrates multiple well-defined lytic lesions involving the anterior tibial cortex. Right: Radiograph of a Brown tumor with pathologic fracture of the elbow demonstrates a well-defined ... More
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 9
Publisher: American Registry of Pathology
Published: 01 November 2021
DOI:
10.55418/9781933477176-2
ISBN-10: 1-933477-17-2
ISBN: 978-1-933477-17-6
... PTEN Carcinomas of breast, thyroid gland, and endometrium Apart from the cancers of the renal pelvis included in the American Cancer Society statistics, new cases of renal cell carcinoma in the United States in 2019 were estimated at 61,000 ( 2 , 13 ). Table 2-3 shows the relative proportions...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 9
Publisher: American Registry of Pathology
Published: 01 November 2021
DOI:
10.55418/9781933477176-1
ISBN-10: 1-933477-17-2
ISBN: 978-1-933477-17-6
... laterally from the outermost tumor cells, it is often possible to recognize that these cells are within the same tissue layer as perirenal fat ( fig. 1-128 , left). In other cases, tumor protrudes through the capsule in a “mushroom-like” fashion, similar to that characteristically seen in follicular thyroid...
