... by immunohistochemistry. Cases may reveal a superimposed pneumonia with intra-alveolar neutrophil infiltration. Lymphoid organs such as the thymus gland, lymph nodes, and spleen show lymphocyte depletion ( 31 ). In infants with encephalopathy, there may be cerebral hemorrhages and cortical atrophy. Laboratory Diagnosis...

.... Travis   WD , Brambilla   E , Burke   AE , Marx   AP , Nicholson   AG . WHO classification of tumours of the lung, pleura, thymus and heart , 4th ed. Lyon : IARC ; 2015 . 6. Shehata   BM , Cundiff   CA , Lee   K   et al . Exome sequencing of patients with histiocytoid...

... NONINFECTIOUS PERICARDITIS Iatrogenic Pericarditis Radiation-Induced Pericarditis Radiation-induced constrictive pericarditis occurs in up to 10 percent of patients with thoracic malignancies (especially in esophagus and thymus gland) that receive therapeutic radiation. Patients present with symptoms...

...   H , Butany   JW , et al . Cardiac sarcomas . In: Travis   WD , Brambilla   E , Müller-Hemelink   HK , Harris   C , eds. Pathology and genetics of tumours of the lung, pleura, thymus, and heart . Lyon : IARC Press ; 2004 : 273 - 81 . 11. Janigan   D , Husain...

... light chain crystals ( fig. 57-19 ). The crystalline nature is most evident ultrastructurally ( fig. 57-20 ). The cells are most frequent in bone marrow, lungs, lymph nodes, thymus gland, and spleen. The monoclonal light chains are typically kappa isotype, with no specific heavy chain association...

...Table 1-1 ANATOMIC STRUCTURES WITHIN THE FOUR REGIONS OF THE MEDIASTINUM Mediastinal Region ^a Large Structures Small Structures Anterior ^b None Thymus (lower portion) Fibroadipose IMA ^c mediastinal branches Lymph nodes (few) Middle Parietal...

... with a prior cancer diagnosis, especially cancers of the pancreas, bladder, thymus, or breast, are also more prone to be diagnosed with PanNETs; however, it is not clear whether this simply reflects increased detection due to surveillance after the first cancer diagnosis ( 59 ). PanNETs have a broad age...

... artery and the lateral or inferior thyroid vein. The location of the lower parathyroid glands may be variable: they may be located adjacent to the lower thyroid gland or in the thymus, vagus nerve, mediastinum, or other ectopic locations. Ectopic parathyroid glands are identified in 14 to 19 percent...

... , Uysal   AR , Erdogan   G . Adrenal function during tuberculous infection and effects of antituberculosis treatment on endogenous and exogenous steroids . Int J Tuberc Lung Dis   1998 ; 2 : 419 - 24 . 228. Sloper   JC . The pathology of the adrenals, thymus and certain other endocrine...

... of the parathyroid glands and thymus associated with the third and fourth branchial pouches also have arrested thyroid C-cell development ( 217 , 218 ). Aberrant (Ectopic) Thyroid Tissue Thyroid ectopia is defined as functioning thyroid tissue found anywhere other than the usual anatomic location...

...; on aneuploidization, YST; rare cases of STM Neonates and children <6 years; rarely beyond childhood; a broad age range only when occurring in the ovary Sacral region, retroperitoneum, abdomen, anterior mediastinum (thymus), neck, midline brain, testis, ovary, and other rare sites II By default seminoma...

...   AG , eds. WHO classification of tumours of the lung, pleura, thymus and heart , 4th ed . Lyons : IARC ; 2015 . 3. WHO Classification of Tumours Editorial Board . Thoracic tumours , 5th ed . Lyon : IARC ; 2021 . ...

...   AG . WHO classification of tumours of the lung, pleura, thymus, and heart , 4th ed . Lyons : IARC ; 2015 . 91. Shibuya   R , Matsuyama   A , Nakamoto   M , Shiba   E , Kasai   T , Hisaoka   M . The combination of CD99 and NKX2.2, a transcriptional target of EWSR1-FLI1...

... T2 IB II IIIB T3 IB IIIA IIIB T4 IIIB IIIB IIIB M1 IV IV IV a Data from UICC TNM classification of malignant tumours, 8th ed. Oxford: Wiley Blackwell; 2017. Compared to other thoracic staging systems, namely for lung and thymus cancers, the 8th edition of staging...

... p63 Nuclear Squamous cell CA, urothelial CA Also subset lung AdCA PAX8 Nuclear Kidney, thyroid, ovary, endometrium, thymus Polyclonal antibody cross reacts with other PAX family members, e.g., PAX5 (B-cell lymphomas) PSA Cytoplasmic Prostate Limited extent of staining SATB2 Nuclear...

... salivary gland inclusions ( 23 – 25 ). Rare mucoepidermoid carcinomas of the gnathic bones (central mucoepidermoid carcinoma), breast, thymus, and thyroid gland are described ( 26 – 33 ). MUCOEPIDERMOID CARCINOMA SITE DISTRIBUTION Figure 6-1 MUCOEPIDERMOID CARCINOMA SITE DISTRIBUTION Mucoepidermoid...

... is a monogenic autoimmune syndrome caused by mutations in the autoimmune regulator (AIRE) gene on chromosome 21 that encodes a nuclear protein involved in transcriptional processes and the regulation of self-antigen expression in the thymus gland ( 122 ). High titer autoantibodies toward intracellular...