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Book Chapter

Sinonasal Cavity

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-1
ISBN: 978-1-933477-61-9
... in testis (NUTM1) gene on chromosome 15 ( 124 , 125 ). Clinical Features. NUT carcinoma most often arises in midline anatomic sites, and it was formerly known as NUT midline carcinoma. The sinonasal region is a common site of tumor origin. Tumors occur in patients of virtually any age, with young...
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Images
Figure 2-8

HETEROTOPIC/ACCESSORY ADRENAL CORTICAL TISSUE WITHIN THE TESTIS Heterotopi...

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in Congenital Disorders of the Adrenal Gland > Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
HETEROTOPIC/ACCESSORY ADRENAL CORTICAL TISSUE WITHIN THE TESTIS Figure 2-8 HETEROTOPIC/ACCESSORY ADRENAL CORTICAL TISSUE WITHIN THE TESTIS Heterotopic or accessory adrenal cortical tissue is encapsulated and presents as a small nodule within the testicular parenchyma near the hilum of the testis More about this image found in HETEROTOPIC/ACCESSORY ADRENAL CORTICAL TISSUE WITHIN THE TESTIS Heterotopi...
Images
Figure 2-7

ACCESSORY ADRENAL CORTICAL TISSUE A: Longitudinal section of a newborn tes...

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in Congenital Disorders of the Adrenal Gland > Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
ACCESSORY ADRENAL CORTICAL TISSUE Figure 2-7 ACCESSORY ADRENAL CORTICAL TISSUE A: Longitudinal section of a newborn testis shows a nodule of heterotopic/accessory adrenal cortical tissue in the hilum of the testis (arrow), adjacent to the head of the epididymis. B: The adrenal tissue from More about this image found in ACCESSORY ADRENAL CORTICAL TISSUE A: Longitudinal section of a newborn tes...
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Figure 2-15

TESTICULAR ADRENAL REST TUMOR IN A PATIENT WITH SALT-LOSING FORM OF 21-HYDR...

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in Congenital Disorders of the Adrenal Gland > Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
. A small portion of rete testis is present at left. B: Tumor has prominent intersecting bands of fibrous tissue. C: Stain for collagen accentuates the prominent fibrous stroma between lobules. D: The reticulin staining pattern isolates individual and small groups of cells. More about this image found in TESTICULAR ADRENAL REST TUMOR IN A PATIENT WITH SALT-LOSING FORM OF 21-HYDR...
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Figure 1-1

MAJOR BIOSYNTHETIC PATHWAYS FOR STEROIDOGENESIS Both adrenal gland and gon...

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in Physiology, Development, and Anatomy of the Adrenal Glands > Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
-HSD type 3) is expressed in the testis but not in the adrenal glands, which therefore have minimal ability to convert the weak androgens DHEA and androstenedione into testosterone. “17β-HSD” encompasses a large family of isoenzymes encoded by separate genes and differentially expressed in a wide More about this image found in MAJOR BIOSYNTHETIC PATHWAYS FOR STEROIDOGENESIS Both adrenal gland and gon...
Book Chapter

Congenital Disorders of the Adrenal Gland

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-02
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... of cases ( 17 ). In boys, adrenal cortical tissue was found along the spermatic cord in 3.8 percent of children undergoing inguinoscrotal surgery, and in 9.3 percent who were operated on for an undescended testis where a longer segment of spermatic cord was dissected ( 18 ). Using a serial blocking...
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Book Chapter

Adrenal Cortical Nodular Diseases

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-04
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... distribution (lentigines) Myxomas Heart Myxomas Adrenal gland PPNAD with Cushing syndrome Pituitary gland Pituitary GH-secreting neuroendocrine tumor with acromegaly Breast Myxomatosis Ductal adenoma Testis Large cell calcifying Sertoli cell tumor Thyroid gland Follicular nodular...
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Book Chapter

Physiology, Development, and Anatomy of the Adrenal Glands

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-01
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
...-hydroxy-steroid dehydrogenase (17β-HSD type 3) is expressed in the testis but not in the adrenal glands, which therefore have minimal ability to convert the weak androgens DHEA and androstenedione into testosterone. “17β-HSD” encompasses a large family of isoenzymes encoded by separate genes...
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Book Chapter

Hemorrhagic Fevers

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-10
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... in suspected imported cases. Because the virus persists in immunologic privileged sites (such as the eye, testis, and placenta), individuals who are clinically asymptomatic after infection may still transmit the disease. In addition, manifestations of chronic arthritis and uveitis (with long-term vision...
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Book Chapter

Skin and Soft Tissue

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-15
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., eye, muscle, joints, adrenal gland, testis, and other visceral tissues. Occasionally, unusual presentations are seen, including exclusive neural infection, histoid leprosy with lesions in atypical locations, and localized lepromatous leprosy where some lesions are multibacillary and others...
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Book Chapter

Respiratory Tract

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-12
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., bone, and testis. A primary Nocardia keratitis, which can lead to corneal scarring, appears to be on the rise in parts of Asia ( 46 ). Skin lesions occur by systemic bacterial dissemination or through direct inoculation at the infection site. Nocardia brasiliensis is the most frequent...
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Images
Figure 30-40

POLYARTERITIS NODOSA-LIKE VASCULITIS: TESTIS Low-power magnification shows...

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in Vasculitis > Disorders of the Heart and Blood Vessels
Published: 15 November 2023
POLYARTERITIS NODOSA-LIKE VASCULITIS: TESTIS Figure 30-40 POLYARTERITIS NODOSA-LIKE VASCULITIS: TESTIS Low-power magnification shows two arterial branches with concentric fibrinoid necrosis. More about this image found in POLYARTERITIS NODOSA-LIKE VASCULITIS: TESTIS Low-power magnification shows...
Book Chapter

Invasive Carcinomas of the Breast

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-08
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... PALB2 DNA repair in association with BRCA1 No specific findings Pancreas Peutz-Jeghers syndrome SKT11 Suppression of cell division Suggestion of grade 2-3 Hormone receptor positive, HER2 negative GI/Pancreas Gyn Testis/Lung Neurofibromatosis type 1 NF1 Negative...
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Book Chapter

Cardiac Germ Cell Tumors

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch49
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... be cartilage, calcified neuroglial tissue, smooth muscle, mucous glands, intestine, pancreas, respiratory mucosa, ependyma, and bone. A myxoid stroma is often present, similar to that seen in other cardiac tumors. In contrast to teratomas of the testis, nonseminomatous elements rarely occur and, in that sense...
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Book Chapter

Vasculitis

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch30
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... Capillaritis Usually associated with small vessel vasculitis syndrome (MPA or immune-associated), occasionally isolated Necrotizing granulomas Granulomatosis with polyangiitis Eosinophilic vasculitis Eosinophilic granulomatosis with polyangiitis Testis, uterus, gastrointestinal tract PAN-like...
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Book Chapter

Cardiac Myxoma

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch41
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... year later, Carney et al. ( 54 ). defined the myxoma syndrome as the constellation of skin pigmentation, Sertoli cell tumors of the testis, cutaneous myxoma, myxoid fibroadenoma of the breast, adrenal cortical hyperplasia, and pituitary hyperactivity (gigantism). Several subsequent reports have...
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Book Chapter

Metastatic Disease

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch52
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... is not the only involved organ, and metastatic deposits are present in extracardiac sites. In a clinical series, the most common site of origin of secondary cardiac tumors was the lung, followed by mediastinum, liver, uterus, and testis ( 1 ). In autopsy series, late-stage carcinomas involve the heart 8.4 percent...
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Book Chapter

Germ Cell Tumors

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-13
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... teratoma should be classified as mature teratoma, with an explanatory note. Research suggests that the diagnosis of ovarian germ cell tumors should be more closely aligned with testis tumors, including the concept of somatic overgrowth. In particular, a recent study ( 10 ) identified immature teratomas...
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Book Chapter

Normal Ovary

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-01
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... to the rete testis, and is present in the hilar region, separate from the ovary. It consists of epithelial cells arranged in glands, which may be angulated or tubular, and cysts ( fig. 1-10 ) ( 24 , 25 ). There may be papillary formations. The epithelial cells vary from flat to cuboidal; some are ciliated...
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Book Chapter

Other Carcinomas, Miscellaneous Tumors, and Tumor-Like Conditions

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-14
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... histologic types present in the mixed carcinoma. MISCELLANEOUS TUMORS Rete Cystadenoma, Adenoma, and Adenocarcinoma Definition.  Rete cystadenoma, adenoma, and adenocarcinoma are essentially identical to the benign and malignant tumors described in the testis. Clinical Features. Benign...
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