Search Results for system

... rheumatoid arthritis or systemic lupus erythematosus are characteristic enough to be diagnostic. Neoplastic conditions such as squamous cell carcinoma (SCC) may be suggested clinically, but tissue biopsy or fine-needle aspiration (FNA) reveals the absence of an epithelial component. Early stage rheumatoid...

... (rare) or externally with a closed-end blind pouch. General Features. The most commonly used classification for first branchial cleft anomalies is that of Drs. Walter P. Work and Conrad A Proctor, the 2-type system ( 21 ). Type I lesions are ectodermal in origin with close proximity to the external...

... tumor front, with a sharp interface between tumor and bone ( 1 , 32 ). With medullary bone involvement, residual bone islands are seen within the tumor and the tumor invades the haversian system ( fig. 4-10 B ). Other adverse prognostic findings include perineural and lymphovascular invasion ( fig. 4-8A...

.... With the newest AJCC and UICC staging systems, oropharyngeal SCC patients are also staged differently based on p16/HPV status. HPV-independent oropharyngeal SCC has patient demographics, molecular features, and morphologies similar to SCC in the oral cavity and larynx (in a sense, “conventional” head and neck SCC...

..., swallowing, and speaking. In head and neck pathology, it also houses a rich lymphatic network with an organized system of abundant lymph nodes which are a common site for lymphomas, infections, and metastases. The neck can be thought of in many different ways: by components and compartments including...

... in the setting of systemic RDD. Microscopic Findings. RDD is characterized by a proliferation of large histiocytes with pale, eosinophilic cytoplasm. At low power, the presence of alternating pale and dark areas, corresponding to histiocytes and lymphocytes, respectively, is a helpful clue ( fig. 1-11...

... with primary nasopharyngeal lymphomas have systemic B symptoms ( 127 ), and most present with stage II lymphomas. PRIMARY NON-HODGKIN LYMPHOMA OF THE NASOPHARYNX Figure 3-25 PRIMARY NON-HODGKIN LYMPHOMA OF THE NASOPHARYNX Lymphomas are infrequent in the nasopharynx. A,B: Diffuse large B-cell lymphoma...

... Dotta et al. and colleagues published a systemic review of 1,363 cases ( 84 , 340 – 344 ). Clinical Features. OMs have a predilection for patients in the second to fourth decades, with a mean age of about 27 years (range, 1 to 80 years). There is a significant number of pediatric cases reported...

... asymptomatic but strongly associated with T-cell leukemia, myelopathy, and tropical spastic paraparesis Infected T cells infiltrate the central nervous system (CNS) causing an immune response with damage to the nervous system and subsequent diffuse degeneration (axonal loss, demyelination, astrocytosis...

... factors of L. monocytogenes. LATE-ONSET NEONATAL LISTERIOSIS Figure 11-3 LATE-ONSET NEONATAL LISTERIOSIS High-power view of a central nervous system inflammatory lesion. (Courtesy of the CDC PHIL) PLACENTA AND AMNION IN NEONATAL LISTERIOSIS Figure 11-4 PLACENTA AND AMNION IN NEONATAL...

.... (Courtesy of the Centers for Disease Control and Prevention [CDC] Public Health Image Library [PHIL]) CRYPTOCOCCOSIS OF THE LUNG, CENTRAL NERVOUS SYSTEM, AND SKIN Figure 20-3 CRYPTOCOCCOSIS OF THE LUNG, CENTRAL NERVOUS SYSTEM, AND SKIN Variable inflammatory response ranges from granulomatous...

... months to years Central nervous system involvement occurs late Fatal within years if untreated Acute course (<1 year) Central nervous system involvement occurs early Fatal in <6 months if untreated Table 25-2 CLINICAL FEATURES OF HUMAN INFECTIONS BY FREE-LIVING AMEBAE (FLA) Syndrome Genus...

... at the time of diagnosis. Common sites of metastasis are lung, liver, and lymph nodes, and less frequently, bone ( 39 ). Systemic symptoms also may be present ( 40 ), including prominent weight loss, intermittent low-grade fever (possibly related to extensive tumor necrosis), and anorexia. Hypoglycemia...

... features underpinning these conditions, with a critical role in the multidisciplinary team ( 1 ). CUSHING SYNDROME Cushing syndrome is a systemic disorder originally described by Harvey Cushing in 1932 ( 2 ) and caused by excess glucocorticoids that result in alterations in the structure...

...NEUROBLASTOMA AND GANGLIONEUROBLASTOMA Neuroblastoma (NBL) is a primitive neoplasm of neuroectodermal origin that arises in anatomic sites corresponding to the distribution of the sympathoadrenal autonomic nervous system. It is subdivided into three subtypes: undifferentiated, poorly...

... stained for chromogranin A. The term parasympathetic paraganglia is an anatomic designation indicating an association with a classic parasympathetic nerve rather than a physiologic definition implying a role in antagonizing sympathetic nervous system functions. With the exception of the carotid bodies...

... the unifying concept of the paraganglionic system based on analogy of these tissues to sympathetic ganglia ( 2 ). While the chromaffin reaction is now obsolete as a diagnostic tool, the cells of the adrenal medulla still are called “chromaffin cells” and their corresponding tumors are called pheochromocytomas...

...The adrenal glands are composite endocrine organs consisting of the mesodermal-derived cortex and neural crest-derived medulla. These components interact with each other, with peripheral endocrine and nonendocrine tissues, and with the central nervous system (CNS) in order to develop normally...

... equipment available ( 2 ). While the imaging studies leading to the discovery of incidentalomas often result from nonspecific abdominal, genitourinary, or systemic complaints, an occasional additional route to detection of nonendocrine adrenal masses is through the clinical workup of patients who...