ZIKA CONGENITAL SYNDROME Figure 3-4 ZIKA CONGENITAL SYNDROME Microcephaly can be associated with this disease. (Courtesy of the CDC Zika Virus Webpage https://www.cdc.gov/zika/czs/index.html ) More about this image found in ZIKA CONGENITAL SYNDROME Microcephaly can be associated with this disease....

ZIKA VIRUS CONGENITAL SYNDROME Figure 3-7 ZIKA VIRUS CONGENITAL SYNDROME Prominent hydrocephaly (A) and mononuclear inflammatory cell infiltration (B) are seen. (Courtesy of the CDC IDPB) More about this image found in ZIKA VIRUS CONGENITAL SYNDROME Prominent hydrocephaly (A) and mononuclear ...

TIMELINES OF ZOONOTIC CORONAVIRUSES (SEVERE ACUTE RESPIRATORY SYNDROME [SARS] AND MIDDLE EAST REPIRATORY SYNDROME [MERS]) Figure 4-6 TIMELINES OF ZOONOTIC CORONAVIRUSES (SEVERE ACUTE RESPIRATORY SYNDROME [SARS] AND MIDDLE EAST REPIRATORY SYNDROME [MERS]) More about this image found in TIMELINES OF ZOONOTIC CORONAVIRUSES (SEVERE ACUTE RESPIRATORY SYNDROME [SAR...

HANTAVIRUS CARDIOPULMONARY SYNDROME (HCPS) Figure 4-19 HANTAVIRUS CARDIOPULMONARY SYNDROME (HCPS) Typical chest X-ray features of severe pulmonary edema. (Courtesy of the CDC PHIL) More about this image found in HANTAVIRUS CARDIOPULMONARY SYNDROME (HCPS) Typical chest X-ray features of...

HEMORRHAGIC FEVER WITH RENAL SYNDROME (HFRS) Figure 4-20 HEMORRHAGIC FEVER WITH RENAL SYNDROME (HFRS) The kidney shows mild interstitial edema, tubular epithelial degeneration, congestion, and focal early hemorrhage. (Courtesy of the CDC IDPB) More about this image found in HEMORRHAGIC FEVER WITH RENAL SYNDROME (HFRS) The kidney shows mild interst...

HANTAVIRUS CARDIOPULMONARY SYNDROME (HCPS) Figure 4-21 HANTAVIRUS CARDIOPULMONARY SYNDROME (HCPS) Lung tissue with intraalveolar and interstitial edema, early hyaline membrane formation, congestion, and minimal septal lymphocyte infiltration (A,B). The spleen reveals scattered prominent immunobla... More about this image found in HANTAVIRUS CARDIOPULMONARY SYNDROME (HCPS) Lung tissue with intraalveolar ...

VANISHING BILE DUCT SYNDROME Figure 9-26 VANISHING BILE DUCT SYNDROME The central portal tract has an absent bile ductule that has disappeared in the chronic inflammation. More about this image found in VANISHING BILE DUCT SYNDROME The central portal tract has an absent bile d...

DIFFUSE INFILTRATIVE LYMPHOCYTOSIS SYNDROME (DILS) Figure 9-27 DIFFUSE INFILTRATIVE LYMPHOCYTOSIS SYNDROME (DILS) A: Large areas of lung are infiltrated by T cells. B. CD8 immunohistochemistry confirms the CD8 phenotype of the T cells. More about this image found in DIFFUSE INFILTRATIVE LYMPHOCYTOSIS SYNDROME (DILS) A: Large areas of lung ...

IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME (IRIS), TUBERCULOSIS IN A PATIENT ON ANTIRETROVIRALS Figure 9-28 IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME (IRIS), TUBERCULOSIS IN A PATIENT ON ANTIRETROVIRALS A: Bronchial biopsy from a patient with new onset of stridor. A protuberant inflammatory no... More about this image found in IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME (IRIS), TUBERCULOSIS IN A PATIE...

IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME (IRIS), MYCOBACTERIUM-AVIUM COMPLEX (MAC) Figure 9-29 IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME (IRIS), MYCOBACTERIUM-AVIUM COMPLEX (MAC) A: Mesenteric lymph node from a patient on HAART and anti-MAC drugs. Note the abundant macrophages and lymphocytes. B: Granuloma formation and T-cell infiltrate on CD4 immunohistochemical stain. C: Ziehl-Neelsen stain shows masses of fragmented acid-fast bacilli within macrophages. (Courtesy of the JPC) More about this image found in IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME (IRIS), MYCOBACTERIUM-A...

IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME (IRIS), CRYPTOCOCCAL DISEASE Figure 9-30 IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME (IRIS), CRYPTOCOCCAL DISEASE A: Cryptococcal CNS IRIS shows granulomatous meningitis with necrosis and giant cells. B: Grocott stain shows damaged fungal yeasts in gra... More about this image found in IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME (IRIS), CRYPTOCOCCAL DISEASE A...

IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME (IRIS), JC VIRUS ENCEPHALITIS Figure 9-31 IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME (IRIS), JC VIRUS ENCEPHALITIS A: There is florid cerebral encephalitis with perivascular and neuropil T-cell lymphocytosis. B: Eosinophilic viral inclusion bodies are... More about this image found in IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME (IRIS), JC VIRUS ENCEPHALITIS ...

IMMUNE RECONSTITUTION SYNDROME Figure 9-32 IMMUNE RECONSTITUTION SYNDROME A: Vulva florid inflammation with mucosal erosion, developing after HAART, clinically thought to be lymphoma. B: Mixed inflammatory infiltrate with plasma cells, eosinophils, and focal cells showing herpes simplex virus (H... More about this image found in IMMUNE RECONSTITUTION SYNDROME A: Vulva florid inflammation with mucosal e...

ANAL CYTOMEGALOVIRUS INFECTION IN A PATIENT WITH ACQUIRED IMMUNODEFICIENCY SYNDROME (AIDS) Figure 5-19 ANAL CYTOMEGALOVIRUS INFECTION IN A PATIENT WITH ACQUIRED IMMUNODEFICIENCY SYNDROME (AIDS) A,B: A large number of infected endothelial cells with eccentric compressed nuclei (A) and rarefied per... More about this image found in ANAL CYTOMEGALOVIRUS INFECTION IN A PATIENT WITH ACQUIRED IMMUNODEFICIENCY ...

CYSTOISOSPORA SPP ORGANISMS Figure 26-37 CYSTOISOSPORA SPP ORGANISMS Involvement of the stomach by Cystoisospora parasites (arrow), as part of disseminated disease in patients with acquired immunodeficiency syndrome (AIDS). More about this image found in CYSTOISOSPORA SPP ORGANISMS Involvement of the stomach by...

STAPHYLOCOCCUS AUREUS SKIN ABSCESS Figure 12-13 STAPHYLOCOCCUS AUREUS SKIN ABSCESS Abscess before (A) and after (B) drainage. Typical strawberry tongue (C) seen in Staphylococcus aureus toxic shock syndrome. (All: courtesy of the CDC PHIL) More about this image found in STAPHYLOCOCCUS AUREUS SKIN ABSCESS Abscess before (A) and...

CRYPTOCOCCOSIS Figure 20-2 CRYPTOCOCCOSIS A: Chest-X-ray shows “ground glass” opacities in a patient with adult respiratory distress syndrome. B: Skin involvement with a typical ulcerated papule. (Courtesy of the Centers for Disease Control and Prevention [CDC] Public Health Image Library [PHIL]... More about this image found in CRYPTOCOCCOSIS A: Chest-X-ray shows “ground glass” opacities in a patient ...

DISSEMINATED PNEUMOCYSTOSIS Figure 21-23 DISSEMINATED PNEUMOCYSTOSIS A,B: The characteristic foamy exudate is seen. Gastrointestinal tract involvement, with organisms highlighted on GMS (right). (Courtesy of Dr. R. Geller, Emory University, Atlanta, GA) C,D: Tumoral middle ear spread in an indiv... More about this image found in DISSEMINATED PNEUMOCYSTOSIS A,B: The characteristic foamy exudate is seen....

CRYPTOCOCCOSIS Figure 20-4 CRYPTOCOCCOSIS A: Prominent suppurative granulomatous inflammation is typically seen in immune-competent individuals. (Courtesy of Prof. P. H. McKee, Boussais, France) B: Gelatinous disease, often seen in patients with acquired immunodeficiency syndrome (AIDS) and char... More about this image found in CRYPTOCOCCOSIS A: Prominent suppurative granulomatous inflammation is typi...

HIV CENTRAL NERVOUS SYSTEM DISEASE Figure 9-7 HIV CENTRAL NERVOUS SYSTEM DISEASE A: Brain in HIV-associated dementia syndrome (HAD), with ventricular dilatation and sulcal widening. B: HIV encephalitis shows cortical white matter with multinucleated giant cell encephalitis (MGCE). C: HIV enceph... More about this image found in HIV CENTRAL NERVOUS SYSTEM DISEASE A: Brain in HIV-associated dementia syn...