Search Results for subtype

...NEUROBLASTOMA AND GANGLIONEUROBLASTOMA Neuroblastoma (NBL) is a primitive neoplasm of neuroectodermal origin that arises in anatomic sites corresponding to the distribution of the sympathoadrenal autonomic nervous system. It is subdivided into three subtypes: undifferentiated, poorly...

... correlations have subclassified PBMAD using histologic criteria. Violon et al. ( 30 ) proposed four histopathologic subtypes of PBMAD by combining cytomorphology (proportion of clear, compact, and oncocytic cells) and architecture (fibrous septa formation within nodules, residual adrenal cortex). Subtype 1...

... as the result of the more difficult imaging detection of lesions in the right adrenal if not of a significant size ( 8 ). Adrenal cortical adenomas are classified based on hormonal status into clinical subtypes: aldosterone-producing adenomas, cortisol-producing adenomas, sex hormone-producing adenomas...

... in adrenal pathology has multiple potential applications, from diagnosing benign and adrenal lesions, to the prediction of treatment outcomes, and even the prediction of histopathologic subtypes. Machine learning and radiomic feature extraction from contrast-enhanced CT scans ( 111 , 112 ) or MRI ( 113...

... germline mutation, somatic mutation in SETD2 or ATRX, high somatic mutation burden, a WNT-altered mRNA subtype, and a hypermethylation subtype ( 60 ). Interestingly, ethnic differences show mutations in RAS and FGFR1 more common in Asians and NF1 mutations more common...

... and CACNA1H have been reported in different subtypes of familial hyperaldosteronism. The cascade of steroidogenic enzymes that is involved in aldosterone synthesis include CYP11A1, 3βHSD, CYP21A, and CYP11B2; the latter is specific for aldosterone biosynthesis, and antibodies that can be applied...

... Dev   1998 ; 12 : 3320 - 4 . 21. Tella   SH , Taieb   D , Pacak   K . HIF-2alpha: Achilles’ heel of pseudohypoxic subtype paraganglioma and other related conditions . Eur J Cancer   2017 ; 86 : 1 - 4 . 22. Tischler   AS , Asa   SL . Paraganglia . In: Mills   SE...

... aldosteronism . Horm Metab Res   2020 ; 52 : 421 - 6 . 47. Sun   L , Jiang   Y , Xie   J , et al . Immunohistochemical Analysis of CYP11B2, CYP11B1 and beta-catenin helps subtyping and relates with clinical characteristics of unilateral primary aldosteronism . Front Mol Biosci   2021 ; 8...

... . Single-nuclei and bulk-tissue gene-expression analysis of pheochromocytoma and paraganglioma links disease subtypes with tumor microenvironment . Nat Commun   2022 ; 13 : 6262 . 9. Leonard   EM , Salman   S , Nurse   CA . Sensory processing and integration at the carotid body tripartite...

...-ASSOCIATED DISEASES: EPIDEMIOLOGY, CLINICAL FEATURES, AND LABORATORY MANIFESTATIONS HHV8-Associated Disease Subtypes, Epidemiology Clinical Presentation Laboratory Findings Kaposi sarcoma (KS) Classic or sporadic: elderly individuals Endemic: children, in sub-Saharan Africa HIV associated...

..., cerebellar in location, unicentric, and centered on the granular layer, although these changes are now largely of historic interest. The spongiform change in human prion disease also varies in severity and distribution, not only between the different genetic forms and CJD subtypes, but also within a single...

... is flooded with lymphocytes, with perivascular lymphocytosis. C: CD8 immunohistochemistry stains all the lymphocytes as the CD8-positive T-cell subtype. HUMAN IMMUNODEFICIENCY VIRUS (HIV) Figure 9-1 HUMAN IMMUNODEFICIENCY VIRUS (HIV) A,B: Electron microphotograph of negative stain (A) and schematic (B...

... mucosal atrophy, intestinal metaplasia, epithelial dysplasia, and neoplasia. These complications develop over months to years. H. pylori infection confers an increased risk for non-cardia gastric adenocarcinoma of both intestinal and diffuse subtypes ( 88 ). The chronic antigenic stimulation due...

... to obstruct the airways, with consequent wheezing and the clinical features of croup. In immunocompetent adults, the disease is usually mild to moderate although severe infection can be seen, most frequently in persons over 65 years of age and in the immunosuppressed. There are two antigenic subtypes of RSV...

...Table 20-1 FEATURES OF PEDIATRIC ADULT SUBTYPE MELANOMA Clinical Features  Adolescents; rare in children  Caucasian  Nevus phenotype (large number of acquired melanocytic nevi) Microscopic Findings  Superficial spreading  Nodular  Acral lentiginous (rare...

... in a case of metastatic clear cell sarcoma: are CRTC1-TRIM11 fusion-bearing tumors melanocytomas or clear cell sarcomas?   Am J Surg Pathol   2019 ; 43 : 861 - 3 . 16. Shaikh   WR , Xiong   M , Weinstock   MA . The contribution of nodular subtype to melanoma mortality in the United States...

... . Sensitivity of fluorescence in situ hybridization for melanoma diagnosis using RREB1, MYB, Cep6, and 11q 13 probes in melanoma subtypes . Arch Dermatol   2010 ; 146 : 273 - 8 . EPIDEMIOLOGY MICROSCOPIC FINDINGS CLINICAL FEATURES IMMUNOHISTOCHEMCIAL FINDINGS Cytogenetic Analysis for the Diagnosis of SSM...

... . Racial differences in six major subtypes of melanoma: descriptive epidemiology . BMC Cancer   2016 ; 16 : 691 . 6. Chen   YA , Teer   JK , Eroglu   Z , et al . Translational pathology, genomics and the development of systemic therapies for acral melanoma . Semin Cancer Biol   2020...

... Absent Dermal mitotic rate (per mm²) 2 Microsatellites ^a Absent Neurotropism Absent Lymphovascular invasion Absent Margins ^a Not involved Optional Parameters Useful For Databases Example Clark level IV Histologic subtype...