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Figure 8-31

PHEOCHROMOCYTOMA: INTRACYTOPLASMIC HYALINE GLOBULES These hyaline structur...

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in Pheochromocytoma and Adrenal Medullary Hyperplasia > Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
PHEOCHROMOCYTOMA: INTRACYTOPLASMIC HYALINE GLOBULES Figure 8-31 PHEOCHROMOCYTOMA: INTRACYTOPLASMIC HYALINE GLOBULES These hyaline structures may be found in a few scattered cells or, rarely, as in this case, may be numerous. More about this image found in PHEOCHROMOCYTOMA: INTRACYTOPLASMIC HYALINE GLOBULES These hyaline structur...
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Figure 5-46

ADRENAL CORTICAL ADENOMA IN CUSHING SYNDROME A: A nuclear pseudoinclusion ...

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in Adrenal Cortical Adenoma > Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
ADRENAL CORTICAL ADENOMA IN CUSHING SYNDROME Figure 5-46 ADRENAL CORTICAL ADENOMA IN CUSHING SYNDROME A: A nuclear pseudoinclusion viewed en face in an adrenal cortical adenoma from a patient with Cushing syndrome. The structure is nonspecific and results from irregular deep infolding More about this image found in ADRENAL CORTICAL ADENOMA IN CUSHING SYNDROME A: A nuclear pseudoinclusion ...
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Physiology, Development, and Anatomy of the Adrenal Glands

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-01
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... during embryogenesis and to function normally throughout life. A fundamental knowledge of normal adrenal function, development, and structure is essential to interpret the pathology and pathobiology of these complex organs. Familiarity with normal adrenal development from an anatomic standpoint...
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Figure 30-5

STRUCTURE OF T. VAGINALIS Diagrammatic representation of ...

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in Sexually Transmitted Diseases > Pathology of Non-Helminth Infectious Diseases
Published: 01 September 2024
STRUCTURE OF T. VAGINALIS Figure 30-5 STRUCTURE OF T. VAGINALIS Diagrammatic representation of the structure of T. vaginalis, alongside Giemsa-stained organisms for comparison. More about this image found in STRUCTURE OF T. VAGINALIS Diagrammatic representation of ...
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Paraganglia and Paragangliomas

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-09
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... that these anatomically dispersed structures consisted of cells developmentally, structurally, and functionally related to each other and to sympathetic ganglia. On the basis of that analogy, he coined the term paraganglia ( 1 ). While Kohn’s analogy is still largely viable, it is now recognized that there is more...
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Pheochromocytoma and Adrenal Medullary Hyperplasia

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-08
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
...The largest paraganglion is the adrenal medulla, a sympathetic organ that secretes adrenaline (epinephrine) and noradrenaline (norepinephrine). The adrenal medulla has long been recognized to be structurally and functionally distinct from the adrenal cortex; in older literature, the development...
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Adrenal Cortical Carcinoma

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-06
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... pain and other local compressive symptoms related to tumor growth and invasion of surrounding structures ( 37 ). ACC may infiltrate the periadrenal fat and adjacent organs, including kidney, liver, spleen, and large veins ( 38 ). Approximately 25 percent of these cases present with metastases...
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Neuroblastoma, Ganglioneuroblastoma, and Ganglioneuroma

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-11
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... gross morphology. Some tumors that are localized and not attached to vital (vascular) structures can be resected without preceding chemotherapy ( fig. 11-6 ). However, NBLs have a tendency to envelop vessels and nerves, making complete resection difficult ( fig. 11-7 ). In larger tumors it may...
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Clinicopathologic Features of the Adrenal Cortex

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-03
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... features underpinning these conditions, with a critical role in the multidisciplinary team ( 1 ). CUSHING SYNDROME Cushing syndrome is a systemic disorder originally described by Harvey Cushing in 1932 ( 2 ) and caused by excess glucocorticoids that result in alterations in the structure...
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Adrenal Cortical Adenoma

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-05
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... of adrenal cortical adenoma largely resembles that of the normal adrenal cortex, with cords, nests, or islands of cells in an alveolar arrangement, separated by a thin, delicate and well-organized vascular network, with sinusoidal structures ( fig. 5-19 ) that are clearly highlighted by silver (reticulin...
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Other Adrenal Neoplasms and Tumor-Like Lesions

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-12
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... carcinoma may retain well-developed structural characteristics, such as gland formation, or have a predominantly solid growth pattern within the rich microvasculature of the adrenal gland ( figs. 12-24 – 12-27 ). Spread of tumor within vascular channels may be evident adjacent to the main site of metastasis...
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Adrenal Cortical Nodular Diseases

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-04
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... on microscopy, and blend almost imperceptibly with the adjacent cortex. Extrusions of adrenocortical tissue into the periadrenal fat is frequent and should not be considered a sign of malignancy ( fig. 4-15 ). There may be a structured capsule in dominant nodules. There is a variable mixture of pale-staining...
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Images
Figure 4-1

INFLUENZA VIRUS Schematic illustration of the influenza virus, showing its...

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in Respiratory Tract > Pathology of Non-Helminth Infectious Diseases
Published: 01 September 2024
INFLUENZA VIRUS Figure 4-1 INFLUENZA VIRUS Schematic illustration of the influenza virus, showing its antigenic structure. More about this image found in INFLUENZA VIRUS Schematic illustration of the influenza virus, showing its...
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Figure 21-41

MUCORALES ORGANISMS PAS stain of mucormycosis in skin bio...

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in Respiratory Tract > Pathology of Non-Helminth Infectious Diseases
Published: 01 September 2024
MUCORALES ORGANISMS Figure 21-41 MUCORALES ORGANISMS PAS stain of mucormycosis in skin biopsy. Hypahae are lightly stained in pink, while spores are dark, pink and round (A). Spores and arthroconidia (brick-like structures) are observed in B. More about this image found in MUCORALES ORGANISMS PAS stain of mucormycosis in skin bio...
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Figure 9-33

HUMAN PAPILLOMAVIRUS (HPV) A: Electron microphotograph of a negative stain...

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in Sexually Transmitted and Urogenital Infections > Pathology of Non-Helminth Infectious Diseases
Published: 01 September 2024
HUMAN PAPILLOMAVIRUS (HPV) Figure 9-33 HUMAN PAPILLOMAVIRUS (HPV) A: Electron microphotograph of a negative stain (courtesy of the CDC PHIL) and schematic (right) of HPV structure (left). B: Schematic of HPV genome (not to scale). C: Schematic of mechanism of E6- and E7-mediated HPV More about this image found in HUMAN PAPILLOMAVIRUS (HPV) A: Electron microphotograph of a negative stain...
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Figure 3-34

SUBACUTE SCLEROSING PANENCEPHALITIS NEUROFIBRILLARY TANGLES Neurofibrillar...

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in Central Nervous System > Pathology of Non-Helminth Infectious Diseases
Published: 01 September 2024
SUBACUTE SCLEROSING PANENCEPHALITIS NEUROFIBRILLARY TANGLES Figure 3-34 SUBACUTE SCLEROSING PANENCEPHALITIS NEUROFIBRILLARY TANGLES Neurofibrillary tangles in pyramidal-shaped neurons in the neocortex are flame-shaped linear structures with dark black staining (arrow), in contrast to normal non More about this image found in SUBACUTE SCLEROSING PANENCEPHALITIS NEUROFIBRILLARY TANGLES Neurofibrillar...
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Systemic Infections

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-23
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... and erythema nodosum Lung opacities Enlarged mediastinum Subacute pulmonary Low inoculum Prolonged duration of milder acute pulmonary disease symptoms Focal or patchy lung infiltrate Lymphadenopathy Chronic pulmonary Usually older males, smokers, or those with underlying structural lung disease Fever...
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Sexually Transmitted Diseases

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-30
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... smear background (C). STRUCTURE OF T. VAGINALIS Figure 30-5 STRUCTURE OF T. VAGINALIS Diagrammatic representation of the structure of T. vaginalis, alongside Giemsa-stained organisms for comparison. T. VAGINALIS TROPHOZOITES Figure 30-6 T. VAGINALIS...
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Book Chapter

Overview

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-19
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... and essential to the decomposition of organic matter. Fungi are divided into seven phyla based on their sexual reproductive structures, although only a few of the many genera are known to cause human disease. These medically important fungi are classified according to their pathogenicity ( fig. 19-1 ), growth...
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Prion Diseases

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-02
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... , Hood   L . Genomic structure of the human prion protein gene . Am J Hum Genet   1991 ; 49 : 320 - 9 . 8. Kim   MO , Takada   LT , Wong   K , Forner   SA , Geschwind   MD . Genetic PrP prion diseases . Cold Spring Harb Perspect Biol   2018 ; 10 : a033134 . 9. Iwasaki...
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