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Figure 5-29
Published: 01 December 2024
ADRENAL CORTICAL ADENOMA, STROMAL CHANGES Figure 5-29 ADRENAL CORTICAL ADENOMA, STROMAL CHANGES Some adenomas show focal or predominant areas with stromal changes, either as loose edematous stroma (A) or as more dense and collagenous depositions embedding small clusters of tumor cells (B). More about this image found in ADRENAL CORTICAL ADENOMA, STROMAL CHANGES Some adenomas show focal or pred...
Images
Figure 6-26
Published: 01 December 2024
ADRENAL CORTICAL CARCINOMA: MYXOID VARIANT Figure 6-26 ADRENAL CORTICAL CARCINOMA: MYXOID VARIANT A–C: Myxoid stromal changes are variably in extent and distribution. Neoplastic cells are usually small, grow in cords or thin trabeculae, and have less pronounced cytologic atypia. More about this image found in ADRENAL CORTICAL CARCINOMA: MYXOID VARIANT A–C: Myxoid stromal changes are...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-10
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... renal cell carcinoma Hemangioblastomas Neuroendocrine tumors Pancreatic serous cystadenomas Endolymphatic sac tumors SDHA 5p15.33 PGL5 (paraganglioma type 5) Adrenal and extra-adrenal 1 SDH deficient renal cell carcinoma SDH deficient gastrointestinal stromal tumor SDHB...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-08
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... DEGENERATION This lesion was identified as a large cyst on imaging; focal calcification is present in the wall. An unusual finding is lipid degeneration that can mimic cortical adenoma ( fig. 8-12 ) ( 36 ); these unusual lipid-rich tumors are due to the extreme stromal edema and vacuolization of cytoplasm...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-06
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... proportions of clear or eosinophilic cells, including oncocytes, and by the stromal characteristics. A more pronounced nodular pattern is related to the presence of intersecting broad fibrous bands. A well-defined, usually thick tumor capsule is almost invariably present, and may be interrupted in fronts...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-05
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
..., STROMAL CHANGES Figure 5-29 ADRENAL CORTICAL ADENOMA, STROMAL CHANGES Some adenomas show focal or predominant areas with stromal changes, either as loose edematous stroma (A) or as more dense and collagenous depositions embedding small clusters of tumor cells (B). ADRENAL CORTICAL ADENOMA ASSOCIATED...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-12
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... cortex. Adrenal ganglioneuromas containing Leydig cells with pathognomonic Reinke crystalloids ( fig. 12-18 ) have been reported in two virilized women ( 54 , 55 ), one of whom also had ovarian stromal hyperthecosis and hilus cell hyperplasia ( 55 ). Although these cases are reported as virilizing...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-04
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... cortical nodular diseases is covered in chapter 7 . Adrenal cortical proliferations, usually without clinical or biochemical evidence of hormone hypersecretion, have been described in the context of Carney triad ( 3 ). This is the combination of gastric gastrointestinal stromal tumor (GIST), pulmonary...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-07
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
...-occurrence of adrenocortical carcinoma and gastrointestinal stromal tumor in a patient with neurofibromatosis type 1 and a history of endometrial cancer . Acta Endocrinol (Buchar)   2020 ; 16 : 353 - 8 . 97. Sørensen   SA , Mulvihill   JJ , Nielsen   A . Long-term follow-up of von...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-11
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... cellular and stromal components, and essentially distinguishes NBL, further subdivided into undifferentiated, poorly differentiated, and differentiating; GNBL nodular; GNBL intermixed; and GNBL, maturing and mature ( Table 11-4 ). Table 11-4 NEUROBLASTOMA SUBCLASSIFICATION Tumor Type Subtype...
Images
Figure 5-20
Published: 01 September 2024
CYTOMEGALOVIRUS INFECTION Figure 5-20 CYTOMEGALOVIRUS INFECTION Scattered enlarged atypical stromal cells in a colonic ulcer base (A), confirmed as CMV infection on immunoperoxidase staining (B). More about this image found in CYTOMEGALOVIRUS INFECTION Scattered enlarged atypical stromal cells in a c...
Images
Figure 9-39
Published: 01 September 2024
INVASIVE ENDOCERVICAL ADENOCARCINOMA Figure 9-39 INVASIVE ENDOCERVICAL ADENOCARCINOMA Invading malignant glands with a desmoplastic stromal reaction. More about this image found in INVASIVE ENDOCERVICAL ADENOCARCINOMA Invading malignant glands with a desm...
Images
Figure 5-18
Published: 01 September 2024
CYTOMEGALOVIRUS COLITIS Figure 5-18 CYTOMEGALOVIRUS COLITIS A: The colonic ulcer shows granulation tissue with prominent mixed inflammatory cell infiltration. B,C: Enlarged infected stromal and endothelial cells are present in the ulcer base, with nuclear and cytoplasmic inclusion material. D More about this image found in CYTOMEGALOVIRUS COLITIS A: The colonic ulcer shows granulation tissue with...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-05
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... compressed nuclei (A) and rarefied periodic acid–Schiff (PAS)-positive cytoplasmic inclusion material (B) mimicking signet ring cells. C: CMV immunoperoxidase stain confirms the multiple viral inclusions. CYTOMEGALOVIRUS INFECTION Figure 5-20 CYTOMEGALOVIRUS INFECTION Scattered enlarged atypical stromal...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-01
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., evidence of tumor recurrence, or pathogenic organisms are identified on supplemental special stains. An immunoperoxidase stain for cytomegalovirus (CMV), however, demonstrates unequivocal positivity in isolated atypical endothelial and stromal cells ( fig. 1-4D ). Stool CMV polymerase chain reaction (PCR...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-09
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
...., acute inflammatory myelopathy) Atrophy (serous atrophy, gelatinous transformation) Other pathologies Lymphoid aggregates Plasmacytosis (polyclonal) Non-necrotic microgranulomas (without evident infectious cause) Stromal fibrosis—reticulin increase Macrophage activation syndrome, hemophagocytic...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-18
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... stratified the stages of trachoma on a grading scale, from five or more lymphoid follicles to cicatricial and healed trachoma. As the disease progresses, the abundant granulation tissue may entrap reactive squamous epithelium and mimic epithelial or stromal malignancy ( 23 ). Some of the histologic findings...
Images
Figure 8-17
Published: 01 February 2024
CELLULAR BLUE NEVUS WITH STROMAL EDEMA Figure 8-17 CELLULAR BLUE NEVUS WITH STROMAL EDEMA Small nodular aggregates and nests of cytologically bland melanocytes are seen in a background of edematous stroma with scattered melanophages. More about this image found in CELLULAR BLUE NEVUS WITH STROMAL EDEMA Small nodular aggregates and nests ...
Images
Figure 8-22
Published: 01 January 2024
CARCINOMA WITH OSTEOCLAST-LIKE STROMAL GIANT CELLS Figure 8-22 CARCINOMA WITH OSTEOCLAST-LIKE STROMAL GIANT CELLS Osteoclast-like stromal giant cells are admixed with this invasive breast carcinoma, NST. Stromal hemorrhage may accompany this feature. There is no known prognostic significance More about this image found in CARCINOMA WITH OSTEOCLAST-LIKE STROMAL GIANT CELLS Osteoclast-like stromal...
Images
Figure 2-11
Published: 01 February 2024
DESMOPLASTIC CMN Figure 2-11 DESMOPLASTIC CMN An intradermal proliferation of fusiform melanocytes is associated with stromal desmoplasia (desmoplastic CMN). More about this image found in DESMOPLASTIC CMN An intradermal proliferation of fusiform melanocytes is a...