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stromal

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CELLULAR BLUE NEVUS WITH <span class="search-highlight">STROMAL</span> EDEMA  Small nodular aggregates and nests ...
Published: 01 February 2024
CELLULAR BLUE NEVUS WITH STROMAL EDEMA Figure 8-17 CELLULAR BLUE NEVUS WITH STROMAL EDEMA Small nodular aggregates and nests of cytologically bland melanocytes are seen in a background of edematous stroma with scattered melanophages. More about this image found in CELLULAR BLUE NEVUS WITH STROMAL EDEMA Small nodular aggregates and nests ...
Images
DESMOPLASTIC CMN  An intradermal proliferation of fusiform melanocytes is a...
Published: 01 February 2024
DESMOPLASTIC CMN Figure 2-11 DESMOPLASTIC CMN An intradermal proliferation of fusiform melanocytes is associated with stromal desmoplasia (desmoplastic CMN). More about this image found in DESMOPLASTIC CMN An intradermal proliferation of fusiform melanocytes is a...
Images
HALO NEVUS  The lesion has a cellular inflamed center that is flanked by a ...
Published: 01 February 2024
HALO NEVUS Figure 3-21 HALO NEVUS The lesion has a cellular inflamed center that is flanked by a rim of dermis devoid of dermal melanocytes, stromal edema, and slight hypervascularity (arrows). More about this image found in HALO NEVUS The lesion has a cellular inflamed center that is flanked by a ...
Images
COMMON BLUE NEVUS  Common blue nevus (BN), uniformly pigmented, extends thr...
Published: 01 February 2024
COMMON BLUE NEVUS Figure 8-5 COMMON BLUE NEVUS Common blue nevus (BN), uniformly pigmented, extends through the entire dermis into the superficial subcutis. There is associated mild stromal fibrosis. More about this image found in COMMON BLUE NEVUS Common blue nevus (BN), uniformly pigmented, extends thr...
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FLEXURAL SITE NEVUS  This compound nevus has junctional nests that vary in ...
Published: 01 February 2024
FLEXURAL SITE NEVUS Figure 5-13 FLEXURAL SITE NEVUS This compound nevus has junctional nests that vary in size and shape. Many nests show cell dyscohesion of melanocytes. The intradermal melanocytes are associated with stromal fibrosis. More about this image found in FLEXURAL SITE NEVUS This compound nevus has junctional nests that vary in ...
Images
SCALP NEVUS  A: The compound nevus displays plaque-like growth and has a ju...
Published: 01 February 2024
SCALP NEVUS Figure 5-9 SCALP NEVUS A: The compound nevus displays plaque-like growth and has a junctional shoulder. B: It contains areas displaying features of a dysplastic nevus with fusion of nests, random atypia, and stromal fibrosis. More about this image found in SCALP NEVUS A: The compound nevus displays plaque-like growth and has a ju...
Images
VULVAR NEVUS  A: Compound nevus with nests at the dermoepidermal junction t...
Published: 01 February 2024
VULVAR NEVUS Figure 5-5 VULVAR NEVUS A: Compound nevus with nests at the dermoepidermal junction that vary in size and shape and are focally confluent. There is a mixed population of melanocytes in the dermis composed of larger (*) and smaller cells (arrow). B: There are areas of stromal fibrosi... More about this image found in VULVAR NEVUS A: Compound nevus with nests at the dermoepidermal junction t...
Images
LENTIGO MALIGNA MELANOMA IN SITU  A: Although there is no confluency of mel...
Published: 01 February 2024
LENTIGO MALIGNA MELANOMA IN SITU Figure 13-3 LENTIGO MALIGNA MELANOMA IN SITU A: Although there is no confluency of melanocytes, there is an increased density of solitary units of melanocytes at the dermoepidermal junction and focally above it (white arrows). B: There is also an increased densit... More about this image found in LENTIGO MALIGNA MELANOMA IN SITU A: Although there is no confluency of mel...
Images
PIGMENTED EPITHELIOID MELANOCYTOMA  A: Silhouette of a heavily pigmented co...
Published: 01 February 2024
PIGMENTED EPITHELIOID MELANOCYTOMA Figure 11-4 PIGMENTED EPITHELIOID MELANOCYTOMA A: Silhouette of a heavily pigmented compound tumor from the back of a 22-year-old male. There is associated epidermal hyperplasia. B: Epithelioid to ovoid cells are present, with a vesicular chromatin pattern and ... More about this image found in PIGMENTED EPITHELIOID MELANOCYTOMA A: Silhouette of a heavily pigmented co...
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ACRAL MELANOMA WITH SYRINGOTROPISM: IN SITU AND INVASIVE  A: The melanoma i...
Published: 01 February 2024
ACRAL MELANOMA WITH SYRINGOTROPISM: IN SITU AND INVASIVE Figure 14-8 ACRAL MELANOMA WITH SYRINGOTROPISM: IN SITU AND INVASIVE A: The melanoma in situ displays a mixed lentiginous, nested, and pagetoid pattern. It extends along the epithelial stromal junction of eccrine ducts (white arrows). B,C:... More about this image found in ACRAL MELANOMA WITH SYRINGOTROPISM: IN SITU AND INVASIVE A: The melanoma i...
Images
MELANOMA ARISING IN ASSOCIATION WITH A BLUE NEVUS  A: A nodule of epithelio...
Published: 01 February 2024
MELANOMA ARISING IN ASSOCIATION WITH A BLUE NEVUS Figure 18-1 MELANOMA ARISING IN ASSOCIATION WITH A BLUE NEVUS A: A nodule of epithelioid melanocytes is associated with melanophages as well as pigmented slender and dendritic melanocytes in the surrounding dermis. B,C: The epithelioid melanocytes display nuclear atypia (B) and lack nuclear expression of BAP1 (C), which is retained in melanophages and stromal cells. D: The epithelioid melanocytes diffusely express PRAME (preferentially expressed antigen in melanoma). The tumor carried a GNAQ 209L mutation. More about this image found in MELANOMA ARISING IN ASSOCIATION WITH A BLUE NEVUS A: A nodule of epithelio...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-05
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... atypical nevi, there is focal pagetosis and/or adnexal extension of junctional melanocytes. Intradermal melanocytes may be associated with stromal fibrosis and inflammation ( fig. 5-5 ). Cytologic atypia is common. These lesions may show overlap with what has been reported as “dysplastic nevi” at other...
Images
MELANOMA ARISING IN ASSOCIATION WITH A PLAQUE BLUE NEVUS  A: A densely cell...
Published: 01 February 2024
MELANOMA ARISING IN ASSOCIATION WITH A PLAQUE BLUE NEVUS Figure 18-4 MELANOMA ARISING IN ASSOCIATION WITH A PLAQUE BLUE NEVUS A: A densely cellular nodule is present in the subcutis in association with a portion of a broad plaque-type blue nevus. B: Areas highlighted from the benign blue nevus p... More about this image found in MELANOMA ARISING IN ASSOCIATION WITH A PLAQUE BLUE NEVUS A: A densely cell...
Images
CARCINOMA WITH OSTEOCLAST-LIKE <span class="search-highlight">STROMAL</span> GIANT CELLS  Osteoclast-like <span class="search-highlight">stromal</span>...
Published: 01 January 2024
CARCINOMA WITH OSTEOCLAST-LIKE STROMAL GIANT CELLS Figure 8-22 CARCINOMA WITH OSTEOCLAST-LIKE STROMAL GIANT CELLS Osteoclast-like stromal giant cells are admixed with this invasive breast carcinoma, NST. Stromal hemorrhage may accompany this feature. There is no known prognostic significance to t... More about this image found in CARCINOMA WITH OSTEOCLAST-LIKE STROMAL GIANT CELLS Osteoclast-like stromal...
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MULTINUCLEATED <span class="search-highlight">STROMAL</span> GIANT CELLS  These cells percolate through the fibro...
Published: 01 January 2024
MULTINUCLEATED STROMAL GIANT CELLS Figure 1-3 MULTINUCLEATED STROMAL GIANT CELLS These cells percolate through the fibrous stroma. It is important to recognize these as mesenchymal cells, and not misinterpret them as infiltrating carcinoma. More about this image found in MULTINUCLEATED STROMAL GIANT CELLS These cells percolate through the fibro...
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<span class="search-highlight">STROMAL</span> REACTION TO RUPTURED CYST  A: A core needle biopsy specimen shows f...
Published: 01 January 2024
STROMAL REACTION TO RUPTURED CYST Figure 2-21 STROMAL REACTION TO RUPTURED CYST A: A core needle biopsy specimen shows fibroadipose tissue with a chronic inflammatory cell infiltrate and stromal fibrosis. B: High-power view demonstrates histiocytes, lymphocytes, and plasma cells; while not defin... More about this image found in STROMAL REACTION TO RUPTURED CYST A: A core needle biopsy specimen shows f...
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FIBROADENOMA WITH PSEUDOANGIOMATOUS <span class="search-highlight">STROMAL</span> HYPERPLASIA
Published: 01 January 2024
FIBROADENOMA WITH PSEUDOANGIOMATOUS STROMAL HYPERPLASIA Figure 5-12 FIBROADENOMA WITH PSEUDOANGIOMATOUS STROMAL HYPERPLASIA More about this image found in FIBROADENOMA WITH PSEUDOANGIOMATOUS STROMAL HYPERPLASIA
Images
FIBROADENOMA WITH <span class="search-highlight">STROMAL</span> GIANT CELLS  A: Low power demonstrates a well-cir...
Published: 01 January 2024
FIBROADENOMA WITH STROMAL GIANT CELLS Figure 5-14 FIBROADENOMA WITH STROMAL GIANT CELLS A: Low power demonstrates a well-circumscribed fibroepithelial lesion with scattered large, hyperchromatic cells in the stroma. B,C: At intermediate (B) and high (C) power, it becomes apparent that these cell... More about this image found in FIBROADENOMA WITH STROMAL GIANT CELLS A: Low power demonstrates a well-cir...
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HYALINIZED FIBROADENOMA  This case has less <span class="search-highlight">stromal</span> cellularity and more hy...
Published: 01 January 2024
HYALINIZED FIBROADENOMA Figure 5-15 HYALINIZED FIBROADENOMA This case has less stromal cellularity and more hyalinization, as well as several large calcifications. More about this image found in HYALINIZED FIBROADENOMA This case has less stromal cellularity and more hy...
Images
FIBROEPITHELIAL LESION WITH INCREASED <span class="search-highlight">STROMAL</span> CELLULARITY  This lesion has ...
Published: 01 January 2024
FIBROEPITHELIAL LESION WITH INCREASED STROMAL CELLULARITY Figure 5-19 FIBROEPITHELIAL LESION WITH INCREASED STROMAL CELLULARITY This lesion has an intracanalicular growth pattern and hypercellular stroma. It is not possible to determine with certainty whether this is a cellular fibroadenoma or a ... More about this image found in FIBROEPITHELIAL LESION WITH INCREASED STROMAL CELLULARITY This lesion has ...