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Figure 9-22
Published: 01 September 2024
LIVER STEATOSIS Figure 9-22 LIVER STEATOSIS A: Liver macroscopic specimen from a patient treated with didanosine (ddI) HAART, who died of metabolic lactic acidosis and had a soft yellow, diffusely steatotic liver. B: There is pronounced microvesicular steatosis devoid of inflammation. More about this image found in LIVER STEATOSIS A: Liver macroscopic specimen from a patient treated with ...
Images
Figure 5-8
Published: 01 September 2024
CHRONIC HCV HEPATITIS Figure 5-8 CHRONIC HCV HEPATITIS Associated steatosis (A) and scattered eosinophils (B,C) are clues to the diagnosis. More about this image found in CHRONIC HCV HEPATITIS Associated steatosis (A) and scattered eosinophils (...
Images
Figure 5-12
Published: 01 September 2024
SEVERE DENGUE INFECTION/DENGUE HEMORRAGHIC FEVER (DHF) Figure 5-12 SEVERE DENGUE INFECTION/DENGUE HEMORRAGHIC FEVER (DHF) A,B: Early, less striking perivenular hepatic necrosis, sinusoidal congestion, and mild steatosis are seen. (Courtesy of the CDC IDPB) More about this image found in SEVERE DENGUE INFECTION/DENGUE HEMORRAGHIC FEVER (DHF) A,B: Early, less st...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-05
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... (DHF) Figure 5-12 SEVERE DENGUE INFECTION/DENGUE HEMORRAGHIC FEVER (DHF) A,B: Early, less striking perivenular hepatic necrosis, sinusoidal congestion, and mild steatosis are seen. (Courtesy of the CDC IDPB) VIRAL IMMUNOHISTOCHEMISTRY Figure 5-13 VIRAL IMMUNOHISTOCHEMISTRY A: Liver tissue shows...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-10
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... distribution of the liver necrosis contrasts with yellow fever, which typically shows midzonal necrosis and associated steatosis. Macrophages may be associated with these necrotic foci, which typically show little other associated inflammatory responses. Regenerative changes (including increased mitotic...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-09
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... Also seen in HIV1 and 2 infection Drug toxicities NRTI drugs:  Noncirrhotic portal hypertension Early HAART therapies (e.g., azidothymidine [AZT], didanosine [ddI], stvudine [d4T], and abacavir)  Microvesicular steatosis and lactic acidosis Nucleoside reverse transcriptase inhibitor...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-28
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., with prominent of red pulp expansion. There may also be capsular thickening, splenic infarction, and overlying fibrous adhesion. The enlarged liver typically shows marked Kupffer cell hyperplasia, the latter cells parasitized by numerous amastigotes ( 7 ). There may also be hepatic steatosis due to malnutrition...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-27
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... ). Hepatomegaly of malaria is due to engorgement of liver sinusoids, mainly by parasitized erythrocytes, and associated Kupffer cell hyperplasia. Mild steatosis and portal tract lymphoplasmacytosis may be present, and in severe cases, there is frequently centrilobular necrosis due to shock. Chronic malaria can...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-04
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... with patchy cellular degeneration or necrosis, occurs most frequently in the liver (hepatitis, sometimes associated with mild steatosis) and heart (myocarditis, sometimes associated with a serosanguinous effusion). Vasculitis occurs almost exclusively in the skin. Subcarinal and other mediastinal lymph nodes...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch19
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... with sudden death. Histiocytoid cardiomyopathy is rare and has been described almost exclusively in young girls ( 30 ). Patients may present with symptoms of arrhythmia or heart failure. Extracardiac manifestations include corneal opacities, hepatic steatosis, and endocrinopathies. Radiologic Features. Most...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch33
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... inflammation, steatosis, dilatation of portal lymphatics, and periductal fibrosis ( 43 ). So-called portal cavernoma cholangiopathy is characterized by decreases in portal vein and bile ductular branches within triads, obliterated portal veins, and obstructive biliary changes ( 45 ). Lymphatics histologically...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 15
Published: 01 March 2023
10.55418/9781933477275-01
ISBN-10: 1-933477-27-X
ISBN: 978-1-933477-27-5
... in the human fetus . Cell Tissue Res   2005 ; 319 : 423 - 8 . 139. Kuhn   JP , Berthold   F , Mayerle   J , et al   Pancreatic steatosis demonstrated at MR imaging in the general population: clinical relevance . Radiology   2015 ; 276 : 129 - 36 . 140. Jaffe   R . The pancreas...
Images
Figure 10-26
Published: 01 January 2022
MITOCHONDRIAL HEPATOPATHY Figure 10-26 MITOCHONDRIAL HEPATOPATHY Mixed macrovesicular and microvesicular steatosis in mitochondrial hepatopathy due to DGUOK mutation. More about this image found in MITOCHONDRIAL HEPATOPATHY Mixed macrovesicular and microvesicular steatosi...
Images
Figure 9-4
Published: 01 January 2022
MACROVESICULAR STEATOSIS Figure 9-4 MACROVESICULAR STEATOSIS Essentially all cases of macrovesicular steatosis also have hepatocytes with small and intermediate droplets of fat. This finding should not be called mixed microvesicular and macrovesicular steatosis. More about this image found in MACROVESICULAR STEATOSIS Essentially all cases of macrovesicular steatosis...
Images
Figure 9-39
Published: 01 January 2022
MICROVESICULAR STEATOSIS Figure 9-39 MICROVESICULAR STEATOSIS This case showed diffuse microvesicular steatosis. More about this image found in MICROVESICULAR STEATOSIS This case showed diffuse microvesicular steatosis...
Images
Figure 9-5
Published: 01 January 2022
MACROVESICULAR STEATOSIS Figure 9-5 MACROVESICULAR STEATOSIS A: This biopsy shows minimal macrovesicular steatosis with approximately 1 percent macrovesicular steatosis (10X magnification). B: This biopsy of mild macrovesicular steatosis shows approximately 10 percent macrovesicular steatosis More about this image found in MACROVESICULAR STEATOSIS A: This biopsy shows minimal macrovesicular steat...
Images
Figure 1-35
Published: 01 January 2022
PATCH OF MICROVESICULAR STEATOSIS IN NONALCOHOLIC FATTY LIVER DISEASE Figure 1-35 PATCH OF MICROVESICULAR STEATOSIS IN NONALCOHOLIC FATTY LIVER DISEASE This biopsy shows a small distinct nodule of micro vesicular steatosis, in a background of ordinary steatohepatitis. This pattern should More about this image found in PATCH OF MICROVESICULAR STEATOSIS IN NONALCOHOLIC FATTY LIVER DISEASE This...
Images
Figure 9-25
Published: 01 January 2022
PATCHES OF MICROVESICULAR STEATOSIS Figure 9-25 PATCHES OF MICROVESICULAR STEATOSIS Left: A round nodule of hepatocytes shows microvesicular steatosis in a biopsy with otherwise ordinary NAFLD. Right: At higher power, the hepatocyte cytoplasm is bubbly, filled with numerous tiny vacuoles of fat More about this image found in PATCHES OF MICROVESICULAR STEATOSIS Left: A round nodule of hepatocytes sh...
Images
Figure 9-7
Published: 01 January 2022
MACROVESICULAR STEATOSIS Figure 9-7 MACROVESICULAR STEATOSIS Left: In the azonal pattern, macrovesicular steatosis is seen, but the fat shows no clear pattern of zonation. Right: This image shows a panacinar pattern of macrovesicular steatosis. A portal tract is at one edge of this image More about this image found in MACROVESICULAR STEATOSIS Left: In the azonal pattern, macrovesicular steat...
Images
Figure 1-33
Published: 01 January 2022
MICROVESICULAR STEATOSIS Figure 1-33 MICROVESICULAR STEATOSIS The entire liver is diffusely involved by microvesicular steatosis (drug effect). More about this image found in MICROVESICULAR STEATOSIS The entire liver is diffusely involved by microve...