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steatohepatiti
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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch20
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... CAUSES OF PORTAL HYPERTENSION Vascular thrombosis Autoimmune hepatitis Alpha-1 antitrypsin deficiency Primary sclerosing cholangitis Steatohepatitis Toxins Storage diseases Hepatitis B and C Primary biliary cirrhosis Right-sided heart failure Cystic fibrosis...
Images
Published: 01 January 2022
STEATOHEPATITIS: LOBULAR INFLAMMATION Figure 9-15 STEATOHEPATITIS: LOBULAR INFLAMMATION In this case of steatohepatitis, the number of foci of lobular inflammation averaged about 3 over the entire biopsy, but ranged from 1 to 5 in different 20X fields. This field was scored as having 5 foci of lo... More about this image found in STEATOHEPATITIS: LOBULAR INFLAMMATION In this case of steatohepatitis, the...
Images
Published: 01 January 2022
STEATOHEPATITIS Figure 14-2 STEATOHEPATITIS This cirrhotic liver shows steatohepatitis; the patient had the metabolic syndrome. More about this image found in STEATOHEPATITIS This cirrhotic liver shows steatohepatitis; the patient ha...
Images
Published: 01 January 2022
AMIODARONE STEATOHEPATITIS Figure 8-12 AMIODARONE STEATOHEPATITIS Numerous ballooned hepatocytes with prominent Mallory hyaline and minimal fat. More about this image found in AMIODARONE STEATOHEPATITIS Numerous ballooned hepatocytes with prominent M...
Images
Published: 01 January 2022
PORTAL INFLAMMATION Figure 9-21 PORTAL INFLAMMATION The liver shows steatohepatitis and cirrhosis. The portal tracts show focally moderate portal chronic inflammation. More about this image found in PORTAL INFLAMMATION The liver shows steatohepatitis and cirrhosis. The por...
Images
Published: 01 January 2022
ALCOHOL-RELATED STEATOHEPATITIS Figure 9-33 ALCOHOL-RELATED STEATOHEPATITIS A: The lobules show cholestasis. B: There are numerous ballooned hepatocytes and abundant Mallory hyaline. C: The lobular inflammation is neutrophil rich. More about this image found in ALCOHOL-RELATED STEATOHEPATITIS A: The lobules show cholestasis. B: There...
Images
Published: 01 January 2022
ALCOHOL-RELATED STEATOHEPATITIS Figure 9-34 ALCOHOL-RELATED STEATOHEPATITIS The zone 3 region shows hepatocyte drop out and fibrosis, a pattern that historically was called central hyaline necrosis. More about this image found in ALCOHOL-RELATED STEATOHEPATITIS The zone 3 region shows hepatocyte drop ou...
Images
Published: 01 January 2022
ALCOHOL-RELATED STEATOHEPATITIS Figure 9-35 ALCOHOL-RELATED STEATOHEPATITIS The lobules show dense, diffuse pericellular fibrosis. More about this image found in ALCOHOL-RELATED STEATOHEPATITIS The lobules show dense, diffuse pericellul...
Images
Published: 01 January 2022
BALLOON CELLS BUT NOT STEATOHEPATITIS Figure 14-1 BALLOON CELLS BUT NOT STEATOHEPATITIS The periportal hepatocytes have balloon cells in this case of biliary cirrhosis. The patient had no risk factors for fatty liver disease. More about this image found in BALLOON CELLS BUT NOT STEATOHEPATITIS The periportal hepatocytes have ball...
Images
Published: 01 January 2022
NONALCOHOLIC STEATOHEPATITIS (NASH)-RELATED CIRRHOSIS Figure 14-4 NONALCOHOLIC STEATOHEPATITIS (NASH)-RELATED CIRRHOSIS This explanted liver showed cirrhosis in the setting of the metabolic syndrome, but had no pericellular fibrosis. More about this image found in NONALCOHOLIC STEATOHEPATITIS (NASH)-RELATED CIRRHOSIS This explanted liver...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 10
Published: 01 January 2022
10.55418/9781933477183-9
ISBN-10: 1-933477-18-0
ISBN: 978-1-933477-18-3
... with macrovesicular steatosis patterns are further divided into steatosis versus steatohepatitis patterns, in order to stratify for risk of fibrosis progression. The distinction of steatosis and steatohepatitis is based on the presence of active lobular injury in the form of ballooned hepatocytes, lobular hepatitis...
Images
Published: 01 January 2022
LOBULAR ARTERY Figure 9-28 LOBULAR ARTERY A small lobular artery is present in this case of steatohepatitis. More about this image found in LOBULAR ARTERY A small lobular artery is present in this case of steatohep...
Images
in Iron Overload, Wilson Disease, and Other Genetic Liver Diseases
> Non-Neoplastic Diseases of the Liver
Published: 01 January 2022
WILSON DISEASE Figure 10-7 WILSON DISEASE Steatosis and hepatocyte ballooning degeneration may mimic nonalcoholic steatohepatitis. More about this image found in WILSON DISEASE Steatosis and hepatocyte ballooning degeneration may mimic ...
Images
Published: 01 January 2022
NEUTROPHILIC LOBULAR INFLAMMATION Figure 9-19 NEUTROPHILIC LOBULAR INFLAMMATION There is neutrophil-rich inflammation in this case of alcohol-related steatohepatitis. More about this image found in NEUTROPHILIC LOBULAR INFLAMMATION There is neutrophil-rich inflammation in...
Images
Published: 01 January 2022
MODERATE LOBULAR INFLAMMATION Figure 9-16 MODERATE LOBULAR INFLAMMATION This degree of lobular inflammation is unusual for steatohepatitis alone, suggesting an additional disease process (likely drug effect in this case). More about this image found in MODERATE LOBULAR INFLAMMATION This degree of lobular inflammation is unusu...
Images
Published: 01 January 2022
CIRRHOSIS WITH TWO DISEASE PROCESSES Figure 14-5 CIRRHOSIS WITH TWO DISEASE PROCESSES There is cirrhosis with active steatohepatitis, as well as plasma cell-rich hepatitis, consistent with an additional component of autoimmune hepatitis. More about this image found in CIRRHOSIS WITH TWO DISEASE PROCESSES There is cirrhosis with active steato...
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Published: 01 January 2022
PATCH OF MICROVESICULAR STEATOSIS IN NONALCOHOLIC FATTY LIVER DISEASE Figure 1-35 PATCH OF MICROVESICULAR STEATOSIS IN NONALCOHOLIC FATTY LIVER DISEASE This biopsy shows a small distinct nodule of micro vesicular steatosis, in a background of ordinary steatohepatitis. This pattern should not be e... More about this image found in PATCH OF MICROVESICULAR STEATOSIS IN NONALCOHOLIC FATTY LIVER DISEASE This...
Images
Published: 01 January 2022
CHOLESTASIS AND DUCTULAR REACTION RELATED TO TOTAL PARENTERAL NUTRITION Figure 8-18 CHOLESTASIS AND DUCTULAR REACTION RELATED TO TOTAL PARENTERAL NUTRITION This picture can be seen with TPN in both the pediatric and adult patients, while steatosis/steatohepatitis-like changes typically occur in a... More about this image found in CHOLESTASIS AND DUCTULAR REACTION RELATED TO TOTAL PARENTERAL NUTRITION Th...
Images
Published: 01 January 2022
CIRRHOSIS ASSOCIATED WITH THE METABOLIC SYNDROME Figure 9-32 CIRRHOSIS ASSOCIATED WITH THE METABOLIC SYNDROME Left: In this cirrhotic liver, focal changes of active steatohepatitis are present. Right: This cryptogenic cirrhotic liver shows minimal macrovesicular steatosis, no significant inflamm... More about this image found in CIRRHOSIS ASSOCIATED WITH THE METABOLIC SYNDROME Left: In this cirrhotic l...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 10
Published: 01 January 2022
10.55418/9781933477183-14
ISBN-10: 1-933477-18-0
ISBN: 978-1-933477-18-3
... ). The most common causes of cirrhosis are well known, and most cases of cryptogenic cirrhosis result from these common causes, in particular, those diseases in which the histologic findings diminish once the liver becomes cirrhotic, such as steatohepatitis and autoimmune hepatitis. Histologic findings...
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