1-20 of 1155 Search Results for

stain

Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Images
Images
PIGMENTED EPITHELIOID MELANOCYTOMA  A: Silhouette of a heavily pigmented co...
Published: 01 February 2024
PIGMENTED EPITHELIOID MELANOCYTOMA Figure 11-4 PIGMENTED EPITHELIOID MELANOCYTOMA A: Silhouette of a heavily pigmented compound tumor from the back of a 22-year-old male. There is associated epidermal hyperplasia. B: Epithelioid to ovoid cells are present, with a vesicular chromatin pattern and ... More about this image found in PIGMENTED EPITHELIOID MELANOCYTOMA A: Silhouette of a heavily pigmented co...
Images
LYMPHOVASCULAR SPACE INVASION  A: An hematoxylin and eosin (H&amp;E) <span class="search-highlight">stain</span> ...
Published: 01 January 2024
LYMPHOVASCULAR SPACE INVASION Figure 8-4 LYMPHOVASCULAR SPACE INVASION A: An hematoxylin and eosin (H&E) stain demonstrates nests of tumor cells in lymphovascular spaces arrayed around a normal terminal duct lobular unit. In cases of diagnostic uncertainty, such as this example, immunostains ... More about this image found in LYMPHOVASCULAR SPACE INVASION A: An hematoxylin and eosin (H&E) stain ...
Images
INFILTRATING MARGIN  A: H&amp;E <span class="search-highlight">stain</span> of a grade 1 invasive breast carcinom...
Published: 01 January 2024
INFILTRATING MARGIN Figure 8-14 INFILTRATING MARGIN A: H&E stain of a grade 1 invasive breast carcinoma, NST. The infiltrative margin is a helpful clue to the malignant nature of a proliferation composed of small glands. B: In problematic cases, myoepithelial cell markers, such as p63, are h... More about this image found in INFILTRATING MARGIN A: H&E stain of a grade 1 invasive breast carcinom...
Images
INVASIVE CARCINOMA WITH NEUROENDOCRINE FEATURES  A: On H&amp;E <span class="search-highlight">stain</span>, this ...
Published: 01 January 2024
INVASIVE CARCINOMA WITH NEUROENDOCRINE FEATURES Figure 8-21 INVASIVE CARCINOMA WITH NEUROENDOCRINE FEATURES A: On H&E stain, this tumor is characterized by solid sheets of tumor cells with intermediate-grade nuclei that have even chromatin. B: High-power image better demonstrates the nuclear... More about this image found in INVASIVE CARCINOMA WITH NEUROENDOCRINE FEATURES A: On H&E stain, this ...
Images
GATA3 IMMUNOSTAIN  A: H&amp;E <span class="search-highlight">stain</span> of a pleural biopsy with involvement by...
Published: 01 January 2024
GATA3 IMMUNOSTAIN Figure 8-23 GATA3 IMMUNOSTAIN A: H&E stain of a pleural biopsy with involvement by breast carcinoma. B: A GATA3 immunostain is useful for confirming breast origin, in conjunction with patient history and morphologic features seen on the H&E stain. More about this image found in GATA3 IMMUNOSTAIN A: H&E stain of a pleural biopsy with involvement by...
Images
MAMMARY-TYPE BENIGN GLANDULAR INCLUSION  A: On the H&amp;E <span class="search-highlight">stain</span>, two gland...
Published: 01 January 2024
MAMMARY-TYPE BENIGN GLANDULAR INCLUSION Figure 14-15 MAMMARY-TYPE BENIGN GLANDULAR INCLUSION A: On the H&E stain, two glandular structures are present in the lymph node. B: A p63 immunostain highlights a peripheral myoepithelial cell layer. More about this image found in MAMMARY-TYPE BENIGN GLANDULAR INCLUSION A: On the H&E stain, two gland...
Images
EXCISION OF MELANOMA IN SITU  A: A rim of normal skin is between the edge o...
Published: 01 February 2024
EXCISION OF MELANOMA IN SITU Figure 13-15 EXCISION OF MELANOMA IN SITU A: A rim of normal skin is between the edge of the melanoma in situ and the inked side margin (H&E stain). B: Immunostain for PRAME. C: The junctional melanoma cells display nuclear labeling for PRAME. More about this image found in EXCISION OF MELANOMA IN SITU A: A rim of normal skin is between the edge o...
Images
LENTIGO MALIGNA MELANOMA  A: Inflamed lentigo maligna melanoma.  B: It is d...
Published: 01 February 2024
LENTIGO MALIGNA MELANOMA Figure 13-16 LENTIGO MALIGNA MELANOMA A: Inflamed lentigo maligna melanoma. B: It is difficult to determine on the H&E stain whether melanoma cells are admixed with the inflammatory cell infiltrate in the superficial dermis. C: An immunostain for Melan-A highlights ... More about this image found in LENTIGO MALIGNA MELANOMA A: Inflamed lentigo maligna melanoma. B: It is d...
Images
COMPOUND DYSPLASTIC NEVUS WITH RARE PRAME-POSITIVE MELANOCYTES  A: Compound...
Published: 01 February 2024
COMPOUND DYSPLASTIC NEVUS WITH RARE PRAME-POSITIVE MELANOCYTES Figure 4-11 COMPOUND DYSPLASTIC NEVUS WITH RARE PRAME-POSITIVE MELANOCYTES A: Compound dysplastic nevus (hematoxylin and eosin [H&E]-stain). B: Immunostain for PRAME. Most nuclei of junctional melanocytes (long arrow) and intrade... More about this image found in COMPOUND DYSPLASTIC NEVUS WITH RARE PRAME-POSITIVE MELANOCYTES A: Compound...
Images
MYOEPITHELIAL CELL <span class="search-highlight">STAINS</span> IN ADENOSIS  A: In this case of lobular carcinoma...
Published: 01 January 2024
MYOEPITHELIAL CELL STAINS IN ADENOSIS Figure 6-11 MYOEPITHELIAL CELL STAINS IN ADENOSIS A: In this case of lobular carcinoma in situ (LCIS) involving adenosis, the arrangement of some of the epithelial cell nests suggests invasive carcinoma rather than LCIS in adenosis. B: A SMMHC stain highligh... More about this image found in MYOEPITHELIAL CELL STAINS IN ADENOSIS A: In this case of lobular carcinoma...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-16
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
.... By the time a biopsy is performed, tumors are usually deeply invasive. MICROSCOPIC FINDINGS DM is defined by its microscopic features: invasive melanoma associated with a fibrous stroma ( fig. 16-1 ). When reviewed at low magnification using a hematoxylin and eosin (H&E)-stained section, the first...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-13
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... facial nevi or numerous nevi elsewhere, and whether or not the dermoscopic features favored a LM or nevus. IMMUNOHISTOCHEMICAL FINDINGS The diagnosis of LM or LMM is usually established or excluded confidently by a microscopic review of hematoxylin and eosin (H&E)-stained sections and clinical...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-09
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
...). In contrast to many other nevi, apart from blue nevi, diffuse staining with HMB-45 is commonly seen in DPN. Most DPNs show a distinct pattern of staining for beta-catenin and cyclin D1 ( 8 , 9 ). In common melanocytic nevi, expression of beta-catenin and cyclin D1 is restricted to superficial dermal...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-18
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... immunoreactive for melanocyte differentiation antigens, such as Mart1/Melan-A, HMB-45 (gp100), and tyrosinase. They also commonly express SOX10 and S-100 protein, but the staining for S-100 protein may be weak or only focal. Discordance between strong staining for HMB-45 and weak labeling for S-100 protein can...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-11
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... pigmented compound tumor from the back of a 22-year-old male. There is associated epidermal hyperplasia. B: Epithelioid to ovoid cells are present, with a vesicular chromatin pattern and prominent nucleolus. C: Tumor cells (arrows) may show loss of staining for PRKAR1A in contrast to the positive staining...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-04
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
...-POSITIVE MELANOCYTES Figure 4-11 COMPOUND DYSPLASTIC NEVUS WITH RARE PRAME-POSITIVE MELANOCYTES A: Compound dysplastic nevus (hematoxylin and eosin [H&E]-stain). B: Immunostain for PRAME. Most nuclei of junctional melanocytes (long arrow) and intradermal melanocytes (short arrow) are negative...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-21
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... the diagnosis of melanoma even when presented with unusual features. BALLOON CELL/CLEAR CELL MELANOMA Balloon cell/clear cell melanoma is characterized by the presence of tumor cells with distinct cytoplasmic features ( 1 ). On hematoxylin and eosin (H&E)-stained sections, the tumor cells usually...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-08
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... pigment on routine hematoxylin and eosin (H&E)-stained sections. The term hypomelanotic or amelanotic BN ( 23 ) describes occasional melanocytic proliferations with the growth patterns, cytologic features, and mutation profile of a blue nevus that lack recognizable melanin pigment. Any variant of BN...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-19
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... melanocytic neoplasm with atypical features may prompt further analysis by fluorescence in situ hybridization (FISH) to determine the presence or absence of homozygous deletions. Immunohistochemical stains documenting the presence of mutant BRAF or NRAS, or fusion proteins may be used...