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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-12
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... patients, lung primaries predominated, with adenocarcinomas accounting for about two thirds of these cases, followed by small cell, squamous cell, and large cell cancers ( 95 ). Approximately 50 percent of the adrenal metastases were bilateral, emphasizing that bilaterality itself can be a clue...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-06
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... with solid growth lacking morphologic signs of differentiation (i.e., glandular or squamous features). Melan-A is positive in melanoma and may be positive in some renal cell carcinomas (Xp11/TFE3-rearranged renal cell carcinoma) ( 206 ). Another renal cell carcinoma and hepatocellular carcinoma marker, CD10...
Images
Figure 8-10
Published: 01 September 2024
ORAL HAIRY LEUKOPLAKIA Figure 8-10 ORAL HAIRY LEUKOPLAKIA Prominent squamous hyperplasia and confluent parakeratosis are seen at low power. A subcorneal band-like zone of large ballooned epithelial cells with a perinuclear halo is in many of the squamous cells. (Courtesy of the CDC PHIL) More about this image found in ORAL HAIRY LEUKOPLAKIA Prominent squamous hyperplasia and confluent parake...
Images
Figure 9-35
Published: 01 September 2024
COLPOSCOPIC FEATURES OF LOW-GRADE AND HIGH-GRADE SQUAMOUS INTRAEPITHELIAL LESIONS (LSIL, HSIL) AND CARCINOMA Figure 9-35 COLPOSCOPIC FEATURES OF LOW-GRADE AND HIGH-GRADE SQUAMOUS INTRAEPITHELIAL LESIONS (LSIL, HSIL) AND CARCINOMA A: LSIL. B: HSIL. C: Squamous cell carcinoma. (Courtesy of Dr. L More about this image found in COLPOSCOPIC FEATURES OF LOW-GRADE AND HIGH-GRADE SQUAMOUS INTRAEPITHELIAL L...
Images
Figure 22-4
Published: 01 September 2024
PENILE AND ESOPHAGEAL CANDIDIASIS Figure 22-4 PENILE AND ESOPHAGEAL CANDIDIASIS Prominent superficial squamous epithelial neutrophil infiltration (A) (courtesy of Prof. P. McKee, Boussais, France) is contrasted with a case of esophageal candidiasis (B), devoid of associated inflammation More about this image found in PENILE AND ESOPHAGEAL CANDIDIASIS Prominent superficial squamous epithelia...
Images
Figure 9-37
Published: 01 September 2024
in situ (-IN3) with a papillary architecture. H: Invasive squamous cell carcinoma of cervix shows nests of malignant cells with squamous differentiation infiltrating cervical stroma. More about this image found in HSIL AND CARCINOMA A: Cohesive and singly scattered hyperchromatic cells, ...
Images
Figure 9-37
Published: 01 September 2024
in situ (-IN3) with a papillary architecture. H: Invasive squamous cell carcinoma of cervix shows nests of malignant cells with squamous differentiation infiltrating cervical stroma. More about this image found in HSIL AND CARCINOMA A: Cohesive and singly scattered hyperchromatic cells, ...
Images
Figure 30-7
Published: 01 September 2024
TRICHOMONAS Figure 30-7 TRICHOMONAS Wet mount of cervical specimen shows numerous trophozoites in relation to squamous epithelial cells. (Courtesy of the CDC PHIL) More about this image found in TRICHOMONAS Wet mount of cervical specimen shows numerous...
Images
Figure 12-55
Published: 01 September 2024
PULMONARY TUBERCULOSIS Figure 12-55 PULMONARY TUBERCULOSIS Striking fibrillogranular (caseous) necrosis has been extruded into a bronchiole demonstrating extensive squamous metaplasia (top right). More about this image found in PULMONARY TUBERCULOSIS Striking fibrillogranular (caseous) necrosis has be...
Images
Figure 12-18
Published: 01 September 2024
PERTUSSIS IN THE TRACHEA AND BRONCHI Figure 12-18 PERTUSSIS IN THE TRACHEA AND BRONCHI There is degeneration of the epithelium (A, low power; B, high power), with early squamous metaplasia (A). (Courtesy of the CDC IDPB) More about this image found in PERTUSSIS IN THE TRACHEA AND BRONCHI There is degeneration of the epitheli...
Images
Figure 9-42
Published: 01 September 2024
DIFFERENTIAL DIAGNOSIS OF HSIL Figure 9-42 DIFFERENTIAL DIAGNOSIS OF HSIL A: Atrophy with reactive atypia and negative p16 immunohistochemistry (inset) excludes HSIL. B: Immature squamous metaplasia and negative p16 (inset) excludes HSIL. More about this image found in DIFFERENTIAL DIAGNOSIS OF HSIL A: Atrophy with reactive atypia and negativ...
Images
Figure 4-28
Published: 01 September 2024
EARLY MEASLES EXANTHEM Figure 4-28 EARLY MEASLES EXANTHEM Skin biopsy shows spongiosis, mild parakeratosis, and early keratinocyte necrosis (A). MeV immunohistochemistry (B) demonstrates positivity in epidermal squamous epithelium. (Courtesy of the CDC IDPB) More about this image found in EARLY MEASLES EXANTHEM Skin biopsy shows spongiosis, mild parakeratosis, a...
Images
Figure 30-4
Published: 01 September 2024
TRICHOMONAS Figure 30-4 TRICHOMONAS Cervical cytology smears show clusters of neutrophils, reactive squamous epithelial changes (with vague perinuclear halos), and interspersed T. vaginalis organisms (arrows) (A,B). Note the nondescript appearance of the parasites More about this image found in TRICHOMONAS Cervical cytology smears show clusters of neu...
Images
Figure 9-40
Published: 01 September 2024
HSIL/LSIL Figure 9-40 HSIL/LSIL A: HSIL with diffuse, strong cytoplasmic and nuclear (“block”) staining for p16, interpreted as a positive result. B: LSIL on the right (short arrow), while the differential diagnosis for the area on the left (long arrow) includes immature squamous metaplasia More about this image found in HSIL/LSIL A: HSIL with diffuse, strong cytoplasmic and nuclear (“block”) s...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-30
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
...) TRICHOMONAS Figure 30-4 TRICHOMONAS Cervical cytology smears show clusters of neutrophils, reactive squamous epithelial changes (with vague perinuclear halos), and interspersed T. vaginalis organisms (arrows) (A,B). Note the nondescript appearance of the parasites against the granular...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-09
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... (NRTI) drugs Other HAART: Hypersensitivity fulminant hepatitis and massive necrosis Nevirapine, efavirenz, and abacavir Table 9-8 HISTOPATHOLOGIC FEATURES OF LOW-GRADE AND HIGH-GRADE SQUAMOUS INTRAEPITHELIAL LESIONS (LSIL,HSIL) a LSIL HSIL Architectural changes...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-08
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... LEUKOPLAKIA Prominent squamous hyperplasia and confluent parakeratosis are seen at low power. A subcorneal band-like zone of large ballooned epithelial cells with a perinuclear halo is in many of the squamous cells. (Courtesy of the CDC PHIL) EBV-ASSOCIATED NASOPHARYNGEAL CARCINOMA Figure 8-11 EBV...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-18
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., and cicatricial or sclerotic ( 21 ). Microscopically, the lesions typically show pseudoepitheliomatous hyperplasia of the squamous epithelium and epidermal acanthosis. There is a dense inflammatory infiltrate in the dermis or submucosa ( fig. 18-19 ), which is initially composed of abundant neutrophils...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-22
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... of neutrophil microabscess formation. PENILE AND ESOPHAGEAL CANDIDIASIS Figure 22-4 PENILE AND ESOPHAGEAL CANDIDIASIS Prominent superficial squamous epithelial neutrophil infiltration (A) (courtesy of Prof. P. McKee, Boussais, France) is contrasted with a case of esophageal candidiasis (B), devoid...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-06
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... inclusions Mixed dermal inflammatory infiltrate with increased vascularity Molluscum contagiosum Lobular epidermal hyperplasia with basal layer mitotic figures, cytoplasmic vacuolation, and eosinophilic globules in lower epidermis Compression of squamous epithelial nuclei by large intracytoplasmic...