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Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-2
ISBN: 978-1-933477-61-9
... of these tumors arise in the palatine tonsil. It is important to be familiar with these tumors so they will not be overlooked (or misdiagnosed) in routine practice. Hematolymphoid tumors are covered extensively in the Fascicles Tumors of the Bone Marrow and Tumors of the Lymph Nodes and Spleen, so only select...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-7
ISBN: 978-1-933477-61-9
...). Nodal-based diseases in the neck are usually part of systemic disease and share features in common with nodal diseases involving other parts of the body ( 37 , 38 ). Since hematolymphoid tumors are covered extensively in the Fascicles, Tumors of the Bone Marrow and Tumors of the Lymph Nodes and Spleen...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-1
ISBN: 978-1-933477-61-9
... infectious disease, mycobacterial spindle cell tumor may develop in lymph nodes (about 45 percent of cases), skin, mucosal sites, spleen, brain, and bone marrow. The nasal septum seems to be affected in the sinonasal tract ( 494 , 497 – 499 ). The reported cases all involve immunocompromised patients...
Images
Figure 6-9
Published: 01 December 2024
ADRENAL CORTICAL CARCINOMA Figure 6-9 ADRENAL CORTICAL CARCINOMA This large ACC was resected from a 27-year-old woman with virilization. The tumor measured 17 cm in diameter and invaded both kidney and spleen, which necessitated en bloc removal of these organs along with the tumor. More about this image found in ADRENAL CORTICAL CARCINOMA This large ACC was resected from a 27-year-old ...
Images
Figure 12-8
Published: 01 December 2024
ADRENAL HEMANGIOMA Figure 12-8 ADRENAL HEMANGIOMA The well-developed features of anastomosing adrenal hemangioma include a prominent frame work of non endothelial supporting cells creating a “spleen-like” pattern of vascular channels lined by hobnail endothelial cells and containing occasional More about this image found in ADRENAL HEMANGIOMA The well-developed features of anastomosing adrenal hem...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-12
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... Organization (WHO) classification of tumors of endocrine origin ( 13 ). They are now the second most common adrenal incidentaloma, after cortical adenomas in some series ( 14 ). While most myelolipomas arise in the adrenal gland, extra-adrenal locations have been reported, including liver, kidney, spleen...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-06
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... pain and other local compressive symptoms related to tumor growth and invasion of surrounding structures ( 37 ). ACC may infiltrate the periadrenal fat and adjacent organs, including kidney, liver, spleen, and large veins ( 38 ). Approximately 25 percent of these cases present with metastases...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-08
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... of any size, no extra-adrenal invasion T3 Tumor of any size with invasion of surrounding tissues (e.g., liver, pancreas, spleen, kidneys) Regional Lymph Node (N) N Category N Criteria NX Regional lymph nodes cannot be assessed N0 No lymph node metastasis N1 Lymph...
Images
Figure 9-2
Published: 01 September 2024
dendritic cells when present in large amounts. D: Spleen in early HIV infection, with enlarged lymphoid follicles. E: Same case as in D, showing spleen cytology specimen stained with HIVp24 to demonstrate heavy viral load. More about this image found in PERSISTENT GENERALIZED LYMPHADENOPATHY (PGL) A: The lymph node has irregul...
Images
Figure 27-2
Published: 01 September 2024
MALARIA Figure 27-2 MALARIA Extensive hemozoin pigment accumulation in the liver (A) and spleen (B), with striking dark brown to black tissue discoloration. (Courtesy of Prof. I. W. Simson, University of Pretoria, Pretoria, South Africa) More about this image found in MALARIA Extensive hemozoin pigment accumulation in the liver (A) and splee...
Images
Figure 4-21
Published: 01 September 2024
HANTAVIRUS CARDIOPULMONARY SYNDROME (HCPS) Figure 4-21 HANTAVIRUS CARDIOPULMONARY SYNDROME (HCPS) Lung tissue with intraalveolar and interstitial edema, early hyaline membrane formation, congestion, and minimal septal lymphocyte infiltration (A,B). The spleen reveals scattered prominent More about this image found in HANTAVIRUS CARDIOPULMONARY SYNDROME (HCPS) Lung tissue with intraalveolar ...
Images
Figure 23-8
Published: 01 September 2024
HISTOPLASMA CAPSULATUM VAR. DUBOISII INFECTION Figure 23-8 HISTOPLASMA CAPSULATUM VAR. DUBOISII INFECTION Gross photograph of enlarged spleen shows necrotizing nodules (A). Liver histology illustrates large fungal yeasts, which are much easier to identify on H More about this image found in HISTOPLASMA CAPSULATUM VAR. DUBOISII INFE...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-27
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... to a negative rapid malaria test, and confirmed with in situ hybridization. LIFE CYCLE OF HUMAN PLASMODIUM SPP Figure 27-1 LIFE CYCLE OF HUMAN PLASMODIUM SPP MALARIA Figure 27-2 MALARIA Extensive hemozoin pigment accumulation in the liver (A) and spleen (B), with striking dark brown...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-17
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... Bacillary angiomatosis Localized Multiple papulonodular vasoproliferative lesions, which can be superficial or deep In immunosuppressed individuals (including AIDS) Peliosis Systemic Hemorrhagic and cystic vascular lesions that can affect the liver, spleen, and eyes Lesions are accompanied by fever...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-23
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... HISTOPLASMA CAPSULATUM VAR. DUBOISII INFECTION Gross photograph of enlarged spleen shows necrotizing nodules (A). Liver histology illustrates large fungal yeasts, which are much easier to identify on H&E staining than classic Histoplasma (B). GMS stain shows narrow-neck budding...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-28
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... is characterized by striking reticuloendothelial cell hyperplasia affecting the liver, spleen, bone marrow, and lymph nodes. The phagocytic cells contain large numbers of Leishmania parasites. Massive hepatosplenomegaly occurs in chronic visceral disease and the spleen typically has a mass of over 1,000 g...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-29
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
...Table 29-1 CLINICAL MANIFESTATIONS OF CHAGAS DISEASE Approximate Frequency Clinical Features Mortality Acute disease 1% Occurs within weeks of inoculation Includes fever, malaise, and enlargement of the liver, spleen, and lymph nodes A rash near the eye is known as the Romaña sign...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-04
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... with thrombosis and infarction Endothelial syncytial multinucleated giant cells Organs affected include lung, kidney, spleen, heart, and CNS a 87 a CNS = central nervous system; Ref. = reference. HERPES SIMPLEX VIRUS (HSV) Figure 4-32 HERPES SIMPLEX VIRUS (HSV) A: The lung shows...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-09
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... dendritic cells when present in large amounts. D: Spleen in early HIV infection, with enlarged lymphoid follicles. E: Same case as in D, showing spleen cytology specimen stained with HIVp24 to demonstrate heavy viral load. LYMPHOEPITHELIAL CYST Figure 9-3 LYMPHOEPITHELIAL CYST Salivary gland...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-10
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... effusions, pulmonary edema, and mucosal petechiae ( 11 ). Microscopically, areas of cellular degeneration, either as contiguous, nonzonal foci of necrosis or single cell apoptosis, are typically seen in the liver ( fig. 10-8 ), but can also occur in the spleen, adrenal gland, and heart ( 17 ). The random...