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spleen
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Images
Published: 01 September 2024
PERSISTENT GENERALIZED LYMPHADENOPATHY (PGL) Figure 9-2 PERSISTENT GENERALIZED LYMPHADENOPATHY (PGL) A: The lymph node has irregularly shaped reactive follicles. B: PGL lymph node follicle in center with macrophage phagocytosis and apoptotic debris. C: HIVp24 stains HIV virus in follicular dend... More about this image found in PERSISTENT GENERALIZED LYMPHADENOPATHY (PGL) A: The lymph node has irregul...
Images
Published: 01 September 2024
MALARIA Figure 27-2 MALARIA Extensive hemozoin pigment accumulation in the liver (A) and spleen (B), with striking dark brown to black tissue discoloration. (Courtesy of Prof. I. W. Simson, University of Pretoria, Pretoria, South Africa) More about this image found in MALARIA Extensive hemozoin pigment accumulation in the liver (A) and splee...
Images
Published: 01 September 2024
HANTAVIRUS CARDIOPULMONARY SYNDROME (HCPS) Figure 4-21 HANTAVIRUS CARDIOPULMONARY SYNDROME (HCPS) Lung tissue with intraalveolar and interstitial edema, early hyaline membrane formation, congestion, and minimal septal lymphocyte infiltration (A,B). The spleen reveals scattered prominent immunobla... More about this image found in HANTAVIRUS CARDIOPULMONARY SYNDROME (HCPS) Lung tissue with intraalveolar ...
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Published: 01 September 2024
HISTOPLASMA CAPSULATUM VAR. DUBOISII INFECTION Figure 23-8 HISTOPLASMA CAPSULATUM VAR. DUBOISII INFECTION Gross photograph of enlarged spleen shows necrotizing nodules (A). Liver histology illustrates large fungal yeasts, which are much easier to identify on H&E staining than classic Histoplasma (B). GMS stain shows narrow-neck budding in the larger and more thick-walled yeasts (C). (Courtesy of the CDC PHIL) More about this image found in HISTOPLASMA CAPSULATUM VAR. DUBOISII INFE...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-27
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... are paramount for diagnosing patients residing in nonendemic areas. Pathologic Findings Plasmodial parasites primarily infect the red blood cells, liver, and spleen. The secondary pathology manifested in other organs depends on the type and severity of infection, with the documented spectrum of malarial organ...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-17
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., spleen, and eyes Lesions are accompanied by fever, weight loss, abdominal pain, and organomegaly In immunosuppressed individuals (including AIDS) Other Systemic Bacteremia, myocarditis, endocarditis (“culture negative”), and neuroretinitis BARTONELLOSES Figure 17-2 BARTONELLOSES A,B: Skin lesion...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-23
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... usually appear enmeshed in fibrin (B). Short hyphal forms may be seen in these lesions (C) (GMS stain). HISTOPLASMA CAPSULATUM VAR. DUBOISII INFECTION Figure 23-8 HISTOPLASMA CAPSULATUM VAR. DUBOISII INFECTION Gross photograph of enlarged spleen shows necrotizing...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-28
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... with prominent pseudoepitheliomatous epidermal hyperplasia. Visceral leishmaniasis is characterized by striking reticuloendothelial cell hyperplasia affecting the liver, spleen, bone marrow, and lymph nodes. The phagocytic cells contain large numbers of Leishmania parasites. Massive hepatosplenomegaly...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-29
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... of the liver, spleen, and lymph nodes A rash near the eye is known as the Romaña sign and consists of conjunctivitis, chemosis, and periorbital edema Infection acquired by ingestion also leads to nausea, vomiting, and abdominal pain 0.01-0.05%; mostly in children, due to myocarditis or encephalitis...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-04
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
...) are most frequent in the kidney, liver, CNS, GI tract, and spleen ( 17 ), which may also show depletion of white pulp lymphoid tissue. Mononuclear inflammatory cell infiltration (predominantly lymphocytic), often with patchy cellular degeneration or necrosis, occurs most frequently in the liver (hepatitis...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-09
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... inflammatory lesions seen. Lymphoid System in HIV Infection. The lymphoid system consists of the spleen, lymph nodes, and lymphoid tissue in the gastrointestinal tract and lung. Additionally, all tissues (apart from the central nervous system) have some lymphoid tissue that may become reactive and prominent...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-10
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., areas of cellular degeneration, either as contiguous, nonzonal foci of necrosis or single cell apoptosis, are typically seen in the liver ( fig. 10-8 ), but can also occur in the spleen, adrenal gland, and heart ( 17 ). The random distribution of the liver necrosis contrasts with yellow fever, which...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-21
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... Presentation Initial infection No or minimal symptoms, paracoccidioidin skin test positive, no lung imaging abnormality Can be subclinical disease or lead to persistent infection Acute/subacute disease In patients under 35 years old (juvenile form); affects lymph nodes, spleen, liver, and bone marrow...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-02
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., based on amino acid polymorphisms in codon 129 ( 9 ). The abnormal protein is also demonstrated using immunohistochemistry and Western blot techniques in extraneural tissue, particularly in lymph nodes, tonsils, and spleen. A definitive diagnosis of CJD is made using specific neuropathologic findings...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-11
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... into the lamina propria, where macrophages phagocytize the bacteria. In the immune competent individual, the macrophages are able to clear the bacteria. If any underlying immune suppression is present, the organisms may disseminate via the macrophages to target organs, including the liver and spleen. Macrophage...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-13
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
.... Complications include bowel perforation and rectal bleeding. In septicemic patients, infection of viscera such as the liver, spleen, and heart; intra-abdominal abscess formation; and mesenteric thrombosis may occur. In up to 10 percent of patients, reactive arthritis and erythema nodosum have been described...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-05
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... a mottled red appearance due to patchy hemorrhage. The liver and spleen may also appear congested and the kidneys and lungs may show extensive parenchymal hemorrhages. In the liver, yellow fever and dengue are both characterized microscopically by hepatocellular damage, steatosis, and scant, predominantly...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-12
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... cocci and bacterial antigens in numerous tissues including the lung, meninges, heart, adrenal gland, spleen, liver, and kidney. Laboratory Diagnosis Culture remains the reference standard for the diagnosis of pneumococcal infection but, ideally, sterile body fluids (blood, sputum, other respiratory...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-22
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... and pericarditis due to Candida and Candida-like yeasts (without associated valvular disease) are also well documented ( 13 , 14 ). Intra-abdominal infections may involve the hepatopancreatobiliary organs, spleen, and peritoneum, the latter usually affected in the setting...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-06
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... systemic disease (as illustrated by the eradicated smallpox). Inferences from poxvirus infections causing systemic disease in animal models suggest that after viral entry there is involvement of lymphoid tissue in organs such as lymph nodes, spleen, and bone marrow. This is followed by viremia...
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