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spindle
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Images
Published: 01 December 2024
ADRENAL CORTICAL ADENOMA WITH SPINDLE CELL FEATURES Figure 5-22 ADRENAL CORTICAL ADENOMA WITH SPINDLE CELL FEATURES Areas of this adrenal adenoma show an ill-defined spindle cell pattern. More conventional histology was present in other fields. More about this image found in ADRENAL CORTICAL ADENOMA WITH SPINDLE CELL FEATURES Areas of this adrenal ...
Images
in Pheochromocytoma and Adrenal Medullary Hyperplasia
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
PHEOCHROMOCYTOMA Figure 8-23 PHEOCHROMOCYTOMA Discohesive, elongated, and spindle-shaped tumor cells with ill-defined borders. More about this image found in PHEOCHROMOCYTOMA Discohesive, elongated, and spindle-shaped tumor cells wi...
Images
in Pheochromocytoma and Adrenal Medullary Hyperplasia
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
PHEOCHROMOCYTOMA Figure 8-24 PHEOCHROMOCYTOMA Spindle cell morphology is also seen in tumors with solid cohesive growth. More about this image found in PHEOCHROMOCYTOMA Spindle cell morphology is also seen in tumors with solid...
Images
Published: 01 December 2024
CAROTID BODY PARAGANGLIOMA Figure 9-24 CAROTID BODY PARAGANGLIOMA A: The almost entirely spindle cell composition of this paraganglioma raises the possibility of mesenchymal and other spindle cell neoplasms. B: Reticulin stain highlights the spindle cell pattern. More about this image found in CAROTID BODY PARAGANGLIOMA A: The almost entirely spindle cell composition...
Images
in Neuroblastoma, Ganglioneuroblastoma, and Ganglioneuroma
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
UNDIFFERENTIATED NEUROBLASTOMA WITH SPINDLE CELL DIFFERENTIATION Figure 11-16 UNDIFFERENTIATED NEUROBLASTOMA WITH SPINDLE CELL DIFFERENTIATION This stage 3 NB in a 5-year-old girl was not pretreated and showed this peculiar undifferentiated spindle cell morphology without presence of neuropil, ga... More about this image found in UNDIFFERENTIATED NEUROBLASTOMA WITH SPINDLE CELL DIFFERENTIATION This stag...
Images
in Other Adrenal Neoplasms and Tumor-Like Lesions
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
MALIGNANT ADRENAL PECOMA Figure 12-16 MALIGNANT ADRENAL PECOMA A: Spindle cell area with cytologic atypia and a mitosis. B: Area of extensive necrosis (top of field). More about this image found in MALIGNANT ADRENAL PECOMA A: Spindle cell area with cytologic atypia and a ...
Images
in Other Adrenal Neoplasms and Tumor-Like Lesions
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
MALIGNANT PERIPHERAL NERVE SHEATH TUMOR Figure 12-17 MALIGNANT PERIPHERAL NERVE SHEATH TUMOR Interlacing fascicles of spindle cells and epithelioid cells are present beneath a small area of residual adrenal cortex. More about this image found in MALIGNANT PERIPHERAL NERVE SHEATH TUMOR Interlacing fascicles of spindle c...
Images
in Other Adrenal Neoplasms and Tumor-Like Lesions
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
VARIED APPEARANCES OF ADRENAL PECOMA Figure 12-15 VARIED APPEARANCES OF ADRENAL PECOMA A: Sharply circumscribed areas of eosinophilic spindle cells and uniform clear cells resemble renal cell carcinoma. B: Different area of the same tumor shows a markedly varied population of small and ballooned... More about this image found in VARIED APPEARANCES OF ADRENAL PECOMA A: Sharply circumscribed areas of eos...
Images
in Physiology, Development, and Anatomy of the Adrenal Glands
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
OVARIAN THECAL METAPLASIA Figure 1-36 OVARIAN THECAL METAPLASIA Ovarian thecal metaplasia appears as a broad zone of bland spindle cells. Nests of pale-staining cortical cells are present within the spindle cell component. More about this image found in OVARIAN THECAL METAPLASIA Ovarian thecal metaplasia appears as a broad zon...
Images
in Other Adrenal Neoplasms and Tumor-Like Lesions
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
PRIMARY ADRENAL LEIOMYOMA Figure 12-12 PRIMARY ADRENAL LEIOMYOMA Primary adrenal leiomyoma is composed of interlacing fascicles of spindle cells in various planes of section. No mitotic figures were identified and there is no necrosis. More about this image found in PRIMARY ADRENAL LEIOMYOMA Primary adrenal leiomyoma is composed of interla...
Images
Published: 01 December 2024
CAROTID BODY PARAGANGLIOMA WITH ADJACENT NORMAL CAROTID BODY Figure 9-21 CAROTID BODY PARAGANGLIOMA WITH ADJACENT NORMAL CAROTID BODY The neoplastic cells in this tumor are larger, more spindled, and clearer than the normal carotid body chief cells (at right). More about this image found in CAROTID BODY PARAGANGLIOMA WITH ADJACENT NORMAL CAROTID BODY The neoplasti...
Images
Published: 01 December 2024
ADRENAL CORTICAL CARCINOMA: SARCOMATOID VARIANT Figure 6-27 ADRENAL CORTICAL CARCINOMA: SARCOMATOID VARIANT This tumor is well-circumscribed within the adrenal (A). It has a pure storiform architectural pattern (B) and consists of spindle cells (B) expressing SF1 (C) and Melan-A (D). More about this image found in ADRENAL CORTICAL CARCINOMA: SARCOMATOID VARIANT This tumor is well-circums...
Images
in Other Adrenal Neoplasms and Tumor-Like Lesions
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
ADRENAL CORTICAL “FIBROMA” Figure 12-20 ADRENAL CORTICAL “FIBROMA” A: This tumor measured about 7 mm and was an incidental finding in a patient undergoing radical nephrectomy for a clear cell renal cell carcinoma. B: The tumor is densely fibrotic with bland spindle cells and resembles an ovarian... More about this image found in ADRENAL CORTICAL “FIBROMA” A: This tumor measured about 7 mm and was an in...
Images
in Congenital Disorders of the Adrenal Gland
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
ACCESSORY ADRENAL CORTICAL TISSUE WITH OVARIAN THECAL METAPLASIA Figure 2-9 ACCESSORY ADRENAL CORTICAL TISSUE WITH OVARIAN THECAL METAPLASIA A: The heterotopic adrenal cortical rest was located near the broad ligament in an adult woman. Cortical cells are present in the center of the nodule and a... More about this image found in ACCESSORY ADRENAL CORTICAL TISSUE WITH OVARIAN THECAL METAPLASIA A: The he...
Images
in Other Adrenal Neoplasms and Tumor-Like Lesions
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
KAPOSI SARCOMA EXTENSIVELY INVOLVING ADRENAL GLAND Figure 12-29 KAPOSI SARCOMA EXTENSIVELY INVOLVING ADRENAL GLAND A: Kaposi sarcoma involving the adrenal gland in an adult male with acquired immunodeficiency syndrome (AIDS). The tumor obscures much of normal histology and architecture of the gla... More about this image found in KAPOSI SARCOMA EXTENSIVELY INVOLVING ADRENAL GLAND A: Kaposi sarcoma invol...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-12
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... angiosarcoma usually presents little difficulty in diagnosis when there is a clear vasoformative pattern ( fig. 12-10A ). Problems arise with tumors having a solid pattern composed of epithelioid or spindle cells (seen focally in fig. 12-10B and to a greater extent in fig. 12-10C ). For these tumors...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-08
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... that interdigitate with and surround adjacent cells. Occasional tumors have a spindle cell morphology ( figs. 8-23 , 8-24 ). The tumor cell nuclei are usually round to oval or elongated; they have prominent nucleoli that may be multiple ( fig. 8-25 ). There may be nuclear inclusions that result from intranuclear...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-11
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... differentiated, and differentiating, on the basis of specific histopathologic criteria (see below in Microscopic Findings). Ganglioneuroblastoma (GNBL) is a closely related neoplasm showing variable cytodifferentiation into ganglion cells, accompanied by a spindle cell schwannian stroma. There are two...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-09
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... BODY PARAGANGLIOMA WITH ADJACENT NORMAL CAROTID BODY Figure 9-21 CAROTID BODY PARAGANGLIOMA WITH ADJACENT NORMAL CAROTID BODY The neoplastic cells in this tumor are larger, more spindled, and clearer than the normal carotid body chief cells (at right). URINARY BLADDER PARAGANGLIOMA Figure 9-22...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-05
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
...) staining ( fig. 5-20 ). Still, a wide heterogeneity of architectures may be observed even within the same lesion ( fig. 5-21 ). Occasionally, the tumor cells are focally aligned in slender cords reminiscent of normal zona fasciculata, or have a spindle cell appearance ( fig. 5-22 ), although rarely...
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