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RESECTED NEUROBLASTOMA Figure 11-6 RESECTED NEUROBLASTOMA Gross image of sliced resection specimen of NB without previous chemo therapy treatment. Preexistent adrenal gland in left slice and possible calcifications in second slice from the right. More about this image found in RESECTED NEUROBLASTOMA Gross image of sliced resection specimen of NB with...

NEUROBLASTOMA FOLLOWING CHEMOTHERAPY Figure 11-20 NEUROBLASTOMA FOLLOWING CHEMOTHERAPY This resection specimen showed the typical heterogeneity of neuroblastic tumors with areas of immature cells and stroma (not shown), calcification, but also completely matured areas as shown in this image More about this image found in NEUROBLASTOMA FOLLOWING CHEMOTHERAPY This resection specimen showed the ty...

BILATERAL ORCHIECTOMY SPECIMENS FROM A 25-YEAR-OLD MALE WITH SALT-LOSING FORM OF 21-HYDROXYLASE DEFICIENCY Figure 2-14 BILATERAL ORCHIECTOMY SPECIMENS FROM A 25-YEAR-OLD MALE WITH SALT-LOSING FORM OF 21-HYDROXYLASE DEFICIENCY Both testes were grossly nearly identical and were almost completely More about this image found in BILATERAL ORCHIECTOMY SPECIMENS FROM A 25-YEAR-OLD MALE WITH SALT-LOSING FO...

medullary precursors (same specimen as fig. 9-3 ). B: In this unusual specimen cells from an extra-adrenal paraganglion are being incorporated into adjacent developing adrenal tissue, which also contains typical nests of neuroblast-like medullary progenitors. A developing ganglion composed of similar More about this image found in ABDOMINAL PARAGANGLIA AND ADJACENT DEVELOPING ADRENAL GLAND A: Normal para...

HYALINE GLOBULES IN ADRENAL CORTEX Figure 1-37 HYALINE GLOBULES IN ADRENAL CORTEX These hyaline globules were noted incidentally in the normal part of an adrenal gland removed because of an aldosterone-secreting cortical adenoma. There were no spironolactone bodies in any part of the specimen More about this image found in HYALINE GLOBULES IN ADRENAL CORTEX These hyaline globules were noted incid...

LIVER METASTASIS FROM ADRENAL CORTICAL CARCINOMA Figure 6-38 LIVER METASTASIS FROM ADRENAL CORTICAL CARCINOMA A: Hepatic lobectomy specimen is largely replaced by metastatic ACC. The tumor is mottled tan-yellow. B: Metastatic ACC disrupts the liver parenchyma and has a large nesting pattern. More about this image found in LIVER METASTASIS FROM ADRENAL CORTICAL CARCINOMA A: Hepatic lobectomy spec...

FETAL ADRENAL GLAND AND KIDNEY Figure 1-4 FETAL ADRENAL GLAND AND KIDNEY Coronal sections (left and right) of adrenal gland and kidney from a fetus of about 18 weeks’ gestational age. External aspect of one specimen is at bottom. Medullary tissue is not evident macroscopically at this early More about this image found in FETAL ADRENAL GLAND AND KIDNEY Coronal sections (left and right) of adrena...

ADRENAL NEUROBLASTOMA Figure 11-10 ADRENAL NEUROBLASTOMA A: Cross-section of a 174-g adrenal NB from a 5-month-old boy. There is extensive calcification within the tumor, which appears as yellowish coarse granular areas. B: Specimen radiograph with identical orientation shows extensive foci More about this image found in ADRENAL NEUROBLASTOMA A: Cross-section of a 174-g adrenal NB from a 5-mont...

ABDOMINAL PARAGANGLIOMA Figure 9-11 ABDOMINAL PARAGANGLIOMA This paraganglioma from the abdomen at the origin of the superior mesenteric artery shows a groove (arrow) where the specimen abutted the artery. Bulging areas of fleshy pink-gray and pink-tan tissue contrast with slightly retracted More about this image found in ABDOMINAL PARAGANGLIOMA This paraganglioma from the abdomen at the origin ...

traversing the specimens are adrenal cortex (arrows). More about this image found in BILATERAL GIANT ADRENAL MYELOLIPOMAS The myelolipomas are from an adult ma...

differentiation next to remaining undifferentiated areas and extensive necrosis. (Images are from the initial biopsy specimen.) More about this image found in UNDIFFERENTIATED NEUROBLASTOMA WITH LARGE CELL HISTOLOGY This tumor was or...

ADRENAL CORTICAL CARCINOMA IN A YOUNG PATIENT WITH LI-FRAUMENI SYNDROME Figure 7-8 ADRENAL CORTICAL CARCINOMA IN A YOUNG PATIENT WITH LI-FRAUMENI SYNDROME Nine-month-old boy with 8-cm right adrenal tumor. No signs of hormonal overproduction. Resection specimen shows nuclear pleomorphism More about this image found in ADRENAL CORTICAL CARCINOMA IN A YOUNG PATIENT WITH LI-FRAUMENI SYNDROME Ni...

ADRENAL CORTICAL ADENOMA WITH WORRISOME MORPHOLOGIC FEATURES Figure 5-53 ADRENAL CORTICAL ADENOMA WITH WORRISOME MORPHOLOGIC FEATURES This cortical adenoma was resected because of interval enlargement. The macroscopic specimen (A) shows the adrenal distended by a hemorrhagic infarcted mass More about this image found in ADRENAL CORTICAL ADENOMA WITH WORRISOME MORPHOLOGIC FEATURES This cortical...

of this unusual appearing gross specimen is deeply pigmented and the remainder is amelanotic, with fibrosis and necrosis. B: Melanin pigment is abundant and the tumor cells are moderately pleomorphic with prominent nucleoli. C: Fine needle aspiration of an adrenal mass shows numerous malignant cells, with many More about this image found in PRIMARY ADRENAL MELANOMA A: A 48-year-old woman complained of abdominal pa...

. This specimen is more mature than the one in figure 9-4 , and shows a mixture of chromaffin cells with clear and amphophilic cytoplasm, more fibrous stroma, and partially trabecular architecture. C: Immunohistochemical stain for tyrosine hydroxylase (TH) in paraganglion and developing sympathetic ganglia from More about this image found in NORMAL ABDOMINAL PARAGANGLION A: Low magnification shows proximity of this...

ABDOMINAL PARAGANGLIOMA Figure 9-13 ABDOMINAL PARAGANGLIOMA A: The tumor, from a patient with a hereditary mutation of the SDHB gene (same specimen as in fig. 9-11 ), has mixed nested and trabecular architecture and is composed of monomorphic cells with slightly eosinophilic cytoplasm More about this image found in ABDOMINAL PARAGANGLIOMA A: The tumor, from a patient with a hereditary mut...

CAROTID BODY PARAGANGLIOMA Figure 9-15 CAROTID BODY PARAGANGLIOMA A: Tumor tissue in most parts of the tumor (same specimen as fig. 9-12 ) shows uniform round nests of weakly eosinophilic cells and cavernous blood vessels. B: This section, taken at the interface between the circumscribed More about this image found in CAROTID BODY PARAGANGLIOMA A: Tumor tissue in most parts of the tumor (sam...

CAROTID BODY PARAGANGLIOMA Figure 9-15 CAROTID BODY PARAGANGLIOMA A: Tumor tissue in most parts of the tumor (same specimen as fig. 9-12 ) shows uniform round nests of weakly eosinophilic cells and cavernous blood vessels. B: This section, taken at the interface between the circumscribed More about this image found in CAROTID BODY PARAGANGLIOMA A: Tumor tissue in most parts of the tumor (sam...