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Figure 1-43

NEUROENDOCRINE CARCINOMA, NOT OTHERWISE SPECIFIED A: This tumor was positi...

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in Sinonasal Cavity > Tumors of the Upper Aerodigestive Tract, Ear, and Jaw
Published: 01 June 2025
NEUROENDOCRINE CARCINOMA, NOT OTHERWISE SPECIFIED Figure 1-43 NEUROENDOCRINE CARCINOMA, NOT OTHERWISE SPECIFIED A: This tumor was positive for neuroendocrine markers, and showed rosettes. B: It does not have classic cellular features of either small cell or large cell neuroendocrine carcinoma. More about this image found in NEUROENDOCRINE CARCINOMA, NOT OTHERWISE SPECIFIED A: This tumor was positi...
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Sinonasal Cavity

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-1
ISBN: 978-1-933477-61-9
... carcinomas ex-sinonasal papilloma are squamous cell carcinomas (SCCs) or subtypes thereof (80 to 85 percent). Keratinizing SCC is much more common than nonkeratinizing in the setting of a precursor papilloma ( fig. 1-26 ). Sinonasal undifferentiated carcinoma and carcinoma, not otherwise specified (NOS) have...
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Ear and Temporal Bone

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-8
ISBN: 978-1-933477-61-9
... specified. Imaging studies identify the extent and location of the tumor as a soft tissue density mass in the external auditory canal, but usually the findings are not specific ( fig. 8-65 ) ( 612 , 629 , 630 ). CERUMINOUS ADENOMA Figure 8-65 CERUMINOUS ADENOMA A: Axial CT demonstrates an occluding mass...
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Jaw

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-5
ISBN: 978-1-933477-61-9
... a cytologically bland “ameloblastoma” metastasizes ( fig. 5-17 ). AMELOBLASTOMA IN A LYMPH NODE Figure 5-17 AMELOBLASTOMA IN A LYMPH NODE The tumor is cytologically bland. Primary Intraosseous Carcinoma, Not Otherwise Specified (NOS) Definition.  Primary intraosseous carcinoma (PIOC...
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Skin and Soft Tissue

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-24
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... fluorescence under a Wood lamp; e geophilic; f encompasses tinea faciei; g diaper dermatitis is a clinical variant among infants; NOS = not otherwise specified. Table 24-4 DERMATOPHYTIC CONDITIONS AND THEIR CLINICAL FEATURES, DIFFERENTIAL DIAGNOSES, AND POTENTIAL COMPLICATIONS...
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Respiratory Tract

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-04
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... to international convention on influenza virus nomenclature, antigenic type (most frequently A or B) is specified first, followed (in order) by the host from which it was isolated (e.g., duck, swine), location (usually a city), strain, year, and finally the H and N antigens of the isolate. ...
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Respiratory Tract

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-21
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... attempting to specify a genus). A curious phenomenon occasionally observed with aspergillosis is prominent localized tissue deposition of calcium oxalate crystals. This is due to the production of oxalic acid by the fungi and is seen particularly with saprophytic infection and with A. niger. It may...
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Prognostic Factors, Staging, and Reporting of Melanoma

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-23
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
..., margin status is needed. When a surgical excision is performed and there is no residual tumor, it suffices to document this absence. If there is residual melanoma, the pathologist should document the presence of tumor and specify the margin status. If the margin is positive and the excision was oriented...
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Fibroepithelial Lesions

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-05
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... rule out mucinous carcinoma, as this particular histologic type of cancer is known to mimic fibroadenoma on imaging studies, and may occur in a broad age range of patients. While there are specified histologic criteria that facilitate grading of phyllodes tumors into benign, borderline, and malignant...
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Pathologic Evaluation and Reporting of Breast and Axillary Lymph Node Specimens

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-15
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... and submitted in their entirety. There are no specified criteria for the number of lymph nodes to be excised or identified; although this can vary widely, 10 is an often quoted number that seems to satisfy surgeons and oncologists alike. It is advisable to submit the remaining adipose tissue if fewer than 10...
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Invasive Carcinomas of the Breast

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-08
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... with a specified antibody is required for treatment with a particular drug. PD-L1 testing, however, comes with challenges: not only must each antibody be validated for each companion therapeutic, but the scoring varies, with one assessing percent of immune cells staining (SP 142) ( 59 ) and another reporting...
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Undifferentiated Pleomorphic Sarcoma

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch53
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
..., malignant fibrous histiocytoma, and cardiac sarcoma, not otherwise specified (NOS) likely can be classified as UPS. As such, it is quite likely that UPS is the most common type of primary cardiac sarcoma. For instance, a recent multinational retrospective review of primary cardiac tumors called each...
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Restrictive Cardiomyopathy

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch16
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... of PDGFRA, PDGFRB, FGFR1, PCM1-JAK2  Chronic eosinophilic leukemia, not otherwise specified  Lymphocytic variant of hypereosinophilic syndrome (L-HES)  Polyclonal hypereosinophilia caused by Th2 cytokine production from immunophenotypically aberrant and/or clonal T cells  Idiopathic...
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Arrhythmogenic Cardiomyopathy

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch17
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... cases, it is appropriate to diagnose a cardiomyopathy, not otherwise specified (NOS), and defer to molecular genetic studies. Excess Epicardial Fat. Normal fat in the right ventricle is occasionally mistaken for ACM; the typical distribution of physiologic right ventricular adipose tissue...
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Overview and Classification

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch13
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
...) Muscle, skeletal (N) Nervous (C) Cutaneous (E) Eye (A) Auditory (K) Kidney (G) Gastrointestinal (S) Skeletal (0) Absence of organ/system involvement, e.g., in family members who are healthy mutation carriers; the mutation is specified in E and inheritance in G (N) Family history negative (U) Family...
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Sex Cord-Stromal Tumors

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-12
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... , McCluggage   WG . Sex cord-stromal tumors with steroid cell tumor and fibroma components: report of 2 cases, including one of extraovarian origin . Int J Gynecol Pathol   2019 ; 38 : 151 - 6 . 31. Hayes   M , Scully   RE . Ovarian steroid cell tumors (not otherwise specified...
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Mucinous Ovarian Tumors

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-08
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... of recurrence compared to the infiltrative/destructive pattern ( 15 ). The pathology report must specify the type of invasion encountered. MUCINOUS CARCINOMA WITH EXPANSILE/CONFLUENT INVASION Figure 8-4 MUCINOUS CARCINOMA WITH EXPANSILE/CONFLUENT INVASION Expansile/Confluent Invasion. This invasive...
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Germ Cell Tumors

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-13
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... tissue in the single section with the greatest quantity (see fig. 13-5 ). This is then measured in “low-power fields” (LPF), which correspond to a 4X objective and a 10X eyepiece. The field area, as specified by the World Health Organization (WHO), corresponds to a 4.5-mm field diameter, giving a field...
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Dissection and Reporting of Pancreatic Resection Specimens

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 15
Published: 01 March 2023
10.55418/9781933477275-16
ISBN-10: 1-933477-27-X
ISBN: 978-1-933477-27-5
... ___ Distal pancreatectomy ___ Other (specify): ____________________________ Tumor Site (select all that apply) ___ Pancreatic head ___ Uncinate process ___ Pancreatic body ___ Pancreatic tail ___ Other (specify): ____________________________ Tumor Size Greatest dimension...
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Secondary Neoplasms

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 15
Published: 01 March 2023
10.55418/9781933477275-14
ISBN-10: 1-933477-27-X
ISBN: 978-1-933477-27-5
...%) 23 (8%) 43 (15%) a Includes metastases from stomach, gallbladder, thyroid gland, skin, and other infrequent sites. b RCC = renal cell carcinoma. c Gynecologic neoplasms, not otherwise specified. Table 14-1 ORIGIN OF PANCREATIC METASTASES IN AUTOPSY SERIES...
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