EARLY MEASLES EXANTHEM Figure 4-28 EARLY MEASLES EXANTHEM Skin biopsy shows spongiosis, mild parakeratosis, and early keratinocyte necrosis (A). MeV immunohistochemistry (B) demonstrates positivity in epidermal squamous epithelium. (Courtesy of the CDC IDPB) More about this image found in EARLY MEASLES EXANTHEM Skin biopsy shows spongiosis, mild parakeratosis, a...

HUMAN HERPESVIRUSES 1 TO 3 SKIN LESIONS Figure 6-5 HUMAN HERPESVIRUSES 1 TO 3 SKIN LESIONS The histopathology of the three is similar and shows vesicle formation (A) and characteristic syncytial cells with nuclear inclusions (B,D). Herpes virus is confirmed using specific immunohistochemical stai... More about this image found in HUMAN HERPESVIRUSES 1 TO 3 SKIN LESIONS The histopathology of the three is...

MPOX Figure 6-11 MPOX Microscopic features of skin lesions. (Courtesy of the CDC IDPB) A: Early changes showing a lichenoid papillary dermal and perivascular mixed inflammatory cell infiltrate, which includes lymphocytes, macrophages, and rare eosinophils. Single dyskeratotic cells are visible i... More about this image found in MPOX Microscopic features of skin lesions. (Courtesy of the CDC IDPB) A: ...

MPOX Figure 6-11 MPOX Microscopic features of skin lesions. (Courtesy of the CDC IDPB) A: Early changes showing a lichenoid papillary dermal and perivascular mixed inflammatory cell infiltrate, which includes lymphocytes, macrophages, and rare eosinophils. Single dyskeratotic cells are visible i... More about this image found in MPOX Microscopic features of skin lesions. (Courtesy of the CDC IDPB) A: ...

KAPOSI SARCOMA Figure 8-16 KAPOSI SARCOMA A: Kaposi sarcoma (KS) of the thoracic skin shows numerous characteristic violaceous plaques. (Courtesy of L. M. Gomez, Department of Dermatology, Pontifica Bolivariana University, Medellín, Colombia) B: Palatal mucosa with KS lesions. (Courtesy of the C... More about this image found in KAPOSI SARCOMA A: Kaposi sarcoma (KS) of the thoracic skin shows numerous ...

EBOLA VIRUS IMMUNOHISTOCHEMISTRY Figure 10-4 EBOLA VIRUS IMMUNOHISTOCHEMISTRY A skin biopsy shows strong red positivity (A,B) and filamentous viral particles illustrated on transmission electron microscopy (C). (Courtesy of the CDC IDPB and the CDC PHIL) More about this image found in EBOLA VIRUS IMMUNOHISTOCHEMISTRY A skin biopsy shows strong red positivity...

MENINGOCOCCEMIA Figure 11-7 MENINGOCOCCEMIA Meningococcal skin lesion (A) with relatively inapparent bacterial organisms. Gram stain on heart tissue (B), in contrast, shows numerous, more obvious intracellular gram-negative cocci. (Courtesy of the CDC IDPB) More about this image found in MENINGOCOCCEMIA Meningococcal skin lesion (A) with relatively inapparent b...

SKIN BIOPSY IN PATIENT WITH MENINGOCOCCEMIA Figure 11-10 SKIN BIOPSY IN PATIENT WITH MENINGOCOCCEMIA A: Hematoxylin and eosin (H&E) stain (left) shows leukocytoclastic vasculitis. B: Scant intracellular cocci are seen with immunohistochemistry. (A,B: courtesy of the CDC IDPB) More about this image found in SKIN BIOPSY IN PATIENT WITH MENINGOCOCCEMIA A: Hematoxylin and eosin (H&am...

STAPHYLOCOCCUS AUREUS SKIN ABSCESS Figure 12-13 STAPHYLOCOCCUS AUREUS SKIN ABSCESS Abscess before (A) and after (B) drainage. Typical strawberry tongue (C) seen in Staphylococcus aureus toxic shock syndrome. (All: courtesy of the CDC PHIL) More about this image found in STAPHYLOCOCCUS AUREUS SKIN ABSCESS Abscess before (A) and...

SKIN MANIFESTATIONS OF RICKETTSIAL DISEASES Figure 14-32 SKIN MANIFESTATIONS OF RICKETTSIAL DISEASES The typical diffuse maculopapular rash (A,B) and a rickettsial pox eschar (C) are seen. (Courtesy of the CDC PHIL) More about this image found in SKIN MANIFESTATIONS OF RICKETTSIAL DISEASES The typical diffuse maculopapu...

AFRICAN TICK BITE FEVER Figure 14-33 AFRICAN TICK BITE FEVER The skin lesion shows the typical eschar (A), prominent purpuric dermal erythrocyte extravasation (B), and vasculitic change with striking fibrinoid necrosis and surrounding predominantly mononuclear inflammatory cell infiltration (C). ... More about this image found in AFRICAN TICK BITE FEVER The skin lesion shows the typical eschar (A), prom...

ROCKY MOUNTAIN SPOTTED FEVER Figure 14-36 ROCKY MOUNTAIN SPOTTED FEVER Skin histology showing scant perivascular inflammation on H&E stain (A), with a Rickettsia immunohistochemical stain (B) illustrating striking positivity in relation to a small dermal blood vessel from a skin biopsy. (Courtesy of the CDC IDPB) More about this image found in ROCKY MOUNTAIN SPOTTED FEVER Skin histology showing scant perivascular inf...

GRAM STAIN OF SKIN AND SOFT TISSUE INFECTIONS BY VARIOUS BACTERIA Figure 15-4 GRAM STAIN OF SKIN AND SOFT TISSUE INFECTIONS BY VARIOUS BACTERIA Clostridium spp (gram positive bacilli; A), Streptococcus spp (gram-positive cocci; B), Acinetobacter spp (gram-negative coccobacilli; C) and Klebsiella spp (gram-negative bacilli; D). More about this image found in GRAM STAIN OF SKIN AND SOFT TISSUE INFECTIONS BY VARIOUS BACTERIA ...

HYPERTROPHIC STAGE OF RHINOSCLEROMA Figure 15-11 HYPERTROPHIC STAGE OF RHINOSCLEROMA A,B: In the perinasal skin, clusters and sheets of characteristic Mikulicz cells (A) show abundant foamy cytoplasm (B) containing a large number of intracytoplasmic bacilli. There is also a chronic inflammatory c... More about this image found in HYPERTROPHIC STAGE OF RHINOSCLEROMA A,B: In the perinasal skin, clusters a...

TUBERCULOID LEPROSY Figure 15-14 TUBERCULOID LEPROSY Typical hypopigmented trunk skin lesions. (Courtesy of the CDC PHIL) More about this image found in TUBERCULOID LEPROSY Typical hypopigmented trunk skin lesions. (Courtesy of...

SKIN AND SOFT TISSUE INFECTION WITH MYCOBACTERIUM HAEMOPHILUM Figure 15-30 SKIN AND SOFT TISSUE INFECTION WITH MYCOBACTERIUM HAEMOPHILUM Clinical features include skin nodules, sinuses (A), and an erythematous rash (B). More about this image found in SKIN AND SOFT TISSUE INFECTION WITH MYCOBACTERIUM HAEMOPHILUM...