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Book Chapter

Cardiac Germ Cell Tumors

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch49
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... metastasis has not been reported ( 47 ). A germ cell tumor is a neoplasm of germ cell origin that is classified by histologic type into seminoma (dysgerminoma), embryonal carcinoma, yolk sac tumor (endodermal sinus tumor), choriocarcinoma, teratoma, and mixed types. Most cardiac germ cell...
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Book Chapter

Metastatic Disease

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch52
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... cardiac sarcoma . Hum Pathol   2003 ; 34 : 1074 - 7 . 65. Fang   FM , Ko   SF , Hwang   CH , Wang   CJ . Healing of superior vena cava defect in mediastinal seminoma with invasion . Ann Thorac Surg   2000 ; 70 : 667 - 9 . 66. Saraiva   LR , Brindeiro Filho   DB...
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Book Chapter

Cardiac Angiosarcoma

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch54
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
...   HS , Schwarting   R . Pericardial angiosarcoma after mediastinal irradiation for seminoma. A case report and a review of the literature . Cancer   1996 ; 78 : 912 - 7 . 3. Loap   P , Fourquet   A , Kirova   Y . Cardiac radiation-induced sarcomas: a SEER population-based study...
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Book Chapter

Germ Cell Tumors

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-13
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... and are not associated with immature neuroepithelium. Dysgerminoma Definition.  Dysgerminoma is a germ cell tumor composed of cells resembling primitive germ cells, and is identical to testicular seminoma and extragonadal germinomas ( fig. 13-8 ). DYSGERMINOMAS Figure 13-8 DYSGERMINOMAS A–C: Low...
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Images
Figure 4-60

SEMINOMA Intratubular seminoma adjacent to invasive seminoma fills and exp...

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in Germ Cell Neoplasia in Situ and Tumors Derived from Germ Cell Neoplasia in Situ > Tumors and Tumor-Like Lesions of the Testis and Adjacent Tissues
Published: 01 August 2022
SEMINOMA Figure 4-60 SEMINOMA Intratubular seminoma adjacent to invasive seminoma fills and expands the seminiferous tubules. More about this image found in SEMINOMA Intratubular seminoma adjacent to invasive seminoma fills and exp...
Images
Figure 4-39

SEMINOMA This seminoma forms cords of tumor cells similar to lobular breas...

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in Germ Cell Neoplasia in Situ and Tumors Derived from Germ Cell Neoplasia in Situ > Tumors and Tumor-Like Lesions of the Testis and Adjacent Tissues
Published: 01 August 2022
SEMINOMA Figure 4-39 SEMINOMA This seminoma forms cords of tumor cells similar to lobular breast cancer. The cytoplasm is amphophilic rather than clear. More about this image found in SEMINOMA This seminoma forms cords of tumor cells similar to lobular breas...
Images
Figure 4-43

SEMINOMA In some tumors, seminoma cells grow between preserved seminiferou...

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in Germ Cell Neoplasia in Situ and Tumors Derived from Germ Cell Neoplasia in Situ > Tumors and Tumor-Like Lesions of the Testis and Adjacent Tissues
Published: 01 August 2022
SEMINOMA Figure 4-43 SEMINOMA In some tumors, seminoma cells grow between preserved seminiferous tubules; this is rarely the predominant pattern. More about this image found in SEMINOMA In some tumors, seminoma cells grow between preserved seminiferou...
Images
Figure 4-44

SEMINOMA Left: Seminoma cells are present between tubules adjacent to Leyd...

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in Germ Cell Neoplasia in Situ and Tumors Derived from Germ Cell Neoplasia in Situ > Tumors and Tumor-Like Lesions of the Testis and Adjacent Tissues
Published: 01 August 2022
SEMINOMA Figure 4-44 SEMINOMA Left: Seminoma cells are present between tubules adjacent to Leydig cells. Although the seminoma cells in this example have dense cytoplasm, their nuclei are markedly more atypical than those of the Leydig cells. Right: In this example, seminoma cells with clear More about this image found in SEMINOMA Left: Seminoma cells are present between tubules adjacent to Leyd...
Images
Figure 4-53

SEMINOMA A,B: A rare seminoma with spindle-shaped tumor cells (A) and nucl...

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in Germ Cell Neoplasia in Situ and Tumors Derived from Germ Cell Neoplasia in Situ > Tumors and Tumor-Like Lesions of the Testis and Adjacent Tissues
Published: 01 August 2022
SEMINOMA Figure 4-53 SEMINOMA A,B: A rare seminoma with spindle-shaped tumor cells (A) and nuclear staining for OCT3/4 in both polygonal and spindle cells (B). C: A seminoma with a vaguely fascicular pattern of spindled tumor cells. More about this image found in SEMINOMA A,B: A rare seminoma with spindle-shaped tumor cells (A) and nucl...
Images
Figure 4-54

SEMINOMA The abundant lymphoid infiltrate splits the seminoma cells into p...

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in Germ Cell Neoplasia in Situ and Tumors Derived from Germ Cell Neoplasia in Situ > Tumors and Tumor-Like Lesions of the Testis and Adjacent Tissues
Published: 01 August 2022
SEMINOMA Figure 4-54 SEMINOMA The abundant lymphoid infiltrate splits the seminoma cells into packets. More about this image found in SEMINOMA The abundant lymphoid infiltrate splits the seminoma cells into p...
Images
Figure 4-55

SEMINOMA A prominent lymphoid follicle with seminoma cells at its peripher...

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in Germ Cell Neoplasia in Situ and Tumors Derived from Germ Cell Neoplasia in Situ > Tumors and Tumor-Like Lesions of the Testis and Adjacent Tissues
Published: 01 August 2022
SEMINOMA Figure 4-55 SEMINOMA A prominent lymphoid follicle with seminoma cells at its periphery. More about this image found in SEMINOMA A prominent lymphoid follicle with seminoma cells at its peripher...
Images
Figure 4-58

SEMINOMA An extensive granulomatous reaction in a seminoma masks many of t...

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in Germ Cell Neoplasia in Situ and Tumors Derived from Germ Cell Neoplasia in Situ > Tumors and Tumor-Like Lesions of the Testis and Adjacent Tissues
Published: 01 August 2022
SEMINOMA Figure 4-58 SEMINOMA An extensive granulomatous reaction in a seminoma masks many of the neoplastic cells. The scattered neoplastic cells are highlighted by their clear cytoplasm. More about this image found in SEMINOMA An extensive granulomatous reaction in a seminoma masks many of t...
Images
Figure 4-79

SEMINOMA Fine needle aspiration of a metastatic seminoma shows loosely coh...

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in Germ Cell Neoplasia in Situ and Tumors Derived from Germ Cell Neoplasia in Situ > Tumors and Tumor-Like Lesions of the Testis and Adjacent Tissues
Published: 01 August 2022
SEMINOMA Figure 4-79 SEMINOMA Fine needle aspiration of a metastatic seminoma shows loosely cohesive cells with one or more prominent nucleoli (Papanicolaou stain). More about this image found in SEMINOMA Fine needle aspiration of a metastatic seminoma shows loosely coh...
Images
Figure 4-213

PARTIALLY REGRESSED SEMINOMA Left: A seminoma with an intense lymphocytic ...

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in Germ Cell Neoplasia in Situ and Tumors Derived from Germ Cell Neoplasia in Situ > Tumors and Tumor-Like Lesions of the Testis and Adjacent Tissues
Published: 01 August 2022
PARTIALLY REGRESSED SEMINOMA Figure 4-213 PARTIALLY REGRESSED SEMINOMA Left: A seminoma with an intense lymphocytic reaction (bottom) is adjacent to a large area of regression containing innumerable blood vessels. Right: Higher magnification shows the extreme vascularity of the area More about this image found in PARTIALLY REGRESSED SEMINOMA Left: A seminoma with an intense lymphocytic ...
Images
Figure 9-11

SEMINOMA Individual seminoma cells grow between tubules in association wit...

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in Tumors of Hematopoietic and Lymphoid Origin > Tumors and Tumor-Like Lesions of the Testis and Adjacent Tissues
Published: 01 August 2022
SEMINOMA Figure 9-11 SEMINOMA Individual seminoma cells grow between tubules in association with a dense infiltrate of benign lymphocytes. More about this image found in SEMINOMA Individual seminoma cells grow between tubules in association wit...
Images
Figure 4-75

SEMINOMA An immunohistochemical stain for CD117 shows membranous staining ...

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in Germ Cell Neoplasia in Situ and Tumors Derived from Germ Cell Neoplasia in Situ > Tumors and Tumor-Like Lesions of the Testis and Adjacent Tissues
Published: 01 August 2022
SEMINOMA Figure 4-75 SEMINOMA An immunohistochemical stain for CD117 shows membranous staining of seminoma cells. More about this image found in SEMINOMA An immunohistochemical stain for CD117 shows membranous staining ...
Images
Figure 4-155

SEMINOMA AND CHORIOCARCINOMA The trophoblasts in this tumor, which was pre...

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in Germ Cell Neoplasia in Situ and Tumors Derived from Germ Cell Neoplasia in Situ > Tumors and Tumor-Like Lesions of the Testis and Adjacent Tissues
Published: 01 August 2022
SEMINOMA AND CHORIOCARCINOMA Figure 4-155 SEMINOMA AND CHORIOCARCINOMA The trophoblasts in this tumor, which was predominantly seminoma, create a well-visualized biphasic pattern. More about this image found in SEMINOMA AND CHORIOCARCINOMA The trophoblasts in this tumor, which was pre...
Images
Figure 4-62

SEMINOMA: INTRATUBULAR GRANULOMATOUS INFLAMMATION A marked intratubular gr...

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in Germ Cell Neoplasia in Situ and Tumors Derived from Germ Cell Neoplasia in Situ > Tumors and Tumor-Like Lesions of the Testis and Adjacent Tissues
Published: 01 August 2022
SEMINOMA: INTRATUBULAR GRANULOMATOUS INFLAMMATION Figure 4-62 SEMINOMA: INTRATUBULAR GRANULOMATOUS INFLAMMATION A marked intratubular granulomatous reaction was adjacent to a seminoma with a diffuse granulomatous reaction. More about this image found in SEMINOMA: INTRATUBULAR GRANULOMATOUS INFLAMMATION A marked intratubular gr...
Images
Figure 4-69

SEMINOMA: ADJACENT INTRATUBULAR SYNCYTIOTROPHOBLAST CELL A syncytiotrophob...

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in Germ Cell Neoplasia in Situ and Tumors Derived from Germ Cell Neoplasia in Situ > Tumors and Tumor-Like Lesions of the Testis and Adjacent Tissues
Published: 01 August 2022
SEMINOMA: ADJACENT INTRATUBULAR SYNCYTIOTROPHOBLAST CELL Figure 4-69 SEMINOMA: ADJACENT INTRATUBULAR SYNCYTIOTROPHOBLAST CELL A syncytiotrophoblast cell is seen in a tubule adjacent to seminoma (right). More about this image found in SEMINOMA: ADJACENT INTRATUBULAR SYNCYTIOTROPHOBLAST CELL A syncytiotrophob...
Images
Figure 4-208

PARTIALLY REGRESSED SEMINOMA A diffuse granulomatous reaction leaves only ...

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in Germ Cell Neoplasia in Situ and Tumors Derived from Germ Cell Neoplasia in Situ > Tumors and Tumor-Like Lesions of the Testis and Adjacent Tissues
Published: 01 August 2022
PARTIALLY REGRESSED SEMINOMA Figure 4-208 PARTIALLY REGRESSED SEMINOMA A diffuse granulomatous reaction leaves only a few residual seminoma cells (upper right). More about this image found in PARTIALLY REGRESSED SEMINOMA A diffuse granulomatous reaction leaves only ...