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Figure 8-46
Published: 01 June 2025
SQUAMOUS CELL CARCINOMA OF THE EXTERNAL AUDITORY CANAL Figure 8-46 SQUAMOUS CELL CARCINOMA OF THE EXTERNAL AUDITORY CANAL A,B: Serial sections show tumor filling the canal as an exophytic gray tumor mass (black arrows) involving the anterior and superior walls of the ear canal. (Courtesy of Dr More about this image found in SQUAMOUS CELL CARCINOMA OF THE EXTERNAL AUDITORY CANAL A,B: Serial section...
Images
Figure 8-74
Published: 01 June 2025
CERUMINOUS ADENOCARCINOMA Figure 8-74 CERUMINOUS ADENOCARCINOMA Frozen section of ceruminous adenocarcinoma showing an infiltrative appearance (A), with atypical cells (B). More about this image found in CERUMINOUS ADENOCARCINOMA Frozen section of ceruminous adenocarcinoma show...
Images
Figure 8-80
Published: 01 June 2025
OTOSCLEROSIS Figure 8-80 OTOSCLEROSIS A whole mount-type section shows marked ossification with mature woven bone only. (Courtesy of Dr. A. Sandison, London, United Kingdom) More about this image found in OTOSCLEROSIS A whole mount-type section shows marked ossification with mat...
Images
Figure 8-98
Published: 01 June 2025
MIDDLE EAR NEUROENDOCRINE TUMOR Figure 8-98 MIDDLE EAR NEUROENDOCRINE TUMOR A: At frozen section, an “infiltrative” appearance is noted, with heavy stromal fibrosis, a finding that can mimic carcinoma. B: Involvement of the ossicular bone is frequent, with the bones encased and also infiltrated More about this image found in MIDDLE EAR NEUROENDOCRINE TUMOR A: At frozen section, an “infiltrative” ap...
Images
Figure 8-45
Published: 01 June 2025
SQUAMOUS CELL CARCINOMA Figure 8-45 SQUAMOUS CELL CARCINOMA An external auditory canal specimen serially sectioned (A), with the anatomic structures and specific landmarks outlined (B) to document the exact location of the tumor, and relationship to anatomic structures and margins. (Courtesy More about this image found in SQUAMOUS CELL CARCINOMA An external auditory canal specimen serially secti...
Images
Images
Images
Figure 8-47
Published: 01 June 2025
SQUAMOUS CELL CARCINOMA Figure 8-47 SQUAMOUS CELL CARCINOMA A: A gross temporal bone resection with the malleus and tympanic membrane. B: Serial sections show a tumor filling into the external auditory canal. C: The histology whole mount demonstrates a tumor expanding into the external More about this image found in SQUAMOUS CELL CARCINOMA A: A gross temporal bone resection with the malleu...
Images
Figure 1-147
Published: 01 June 2025
and individual cells are noted within the squamous epithelium. C: Mucosal melanoma with pigmentation seen in the intraepithelial nests. D: Even with tangential sectioning, surface involvement is easy to see in the intact areas of the tumor. More about this image found in MUCOSAL MELANOMA One of the helpful features in documenting primary diseas...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-3
ISBN: 978-1-933477-61-9
... that measure 7 cm or greater ( 89 ). They present as smooth, lobulated masses that on cut section have a gritty texture and display a heterogeneous interior that includes multiloculated cystic and solid areas ( fig. 3-16 ) ( 89 , 98 ). The gross features are similar to their appearance in gonadal sites...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-6
ISBN: 978-1-933477-61-9
.... The mucosa of the true vocal cords has a specialized organization which can only partially be appreciated in standard hematoxylin and eosin (H&E)-stained sections ( fig. 6-3 ). The lamina propria of the true vocal cords lying between the vocal ligament and the overlying squamous epithelium (Reinke space...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-8
ISBN: 978-1-933477-61-9
... Ear The histologic features of the inner ear are much more integrated into functionality, and few surgical pathology specimens are submitted from these sites. The membranous labyrinth has two parts: the sacculocochlear and the utriculovestibular sections, joined by the ductus reuniens, and enclosed...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-7
ISBN: 978-1-933477-61-9
... for a definitive diagnosis based upon cytomorphology alone in the majority of cases. The typical nuclear features include an enlarged oval nucleus with pale evenly distributed chromatin (in contrast to the cleared-out nuclear pattern in histologic sections), frequent longitudinal nuclear grooves, overlapping...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-1
ISBN: 978-1-933477-61-9
... it. The smooth, globular, lobulated, firm to rubbery yellow tan tumors ( fig. 1-79 ) typically have a solid cut section, although frequently with myxoid and cystic degeneration ( 412 , 416 ). Calcifications may be seen. SCHWANNOMA Figure 1-79 SCHWANNOMA A: Nasoendoscopy shows a polypoid mass protruding...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-2
ISBN: 978-1-933477-61-9
... is another differential diagnosis consideration. Morphology is very useful (see differential diagnosis section below), and immunohistochemistry can be of use in the differentiation from nonkeratinizing HPV-associated SCC. While SCC is diffusely positive for p40 (and p63), or at least lacks a specific pattern...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-5
ISBN: 978-1-933477-61-9
... and should be designated as such. When PIOCs arise in cysts, there may be histologic evidence of the preexisting cyst, which may or may not show varying degrees of dysplasia in the epithelial lining depending upon the section. When a cyst transforms, the first evidence is the premalignant dysplastic...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-4
ISBN: 978-1-933477-61-9
.... Throughout the epithelium are “mitosoid bodies,” which represent cellular ballooning and degenerating chromatin and mimic mitotic figures ( fig. 4-37 ) ( 100 , 105 , 108 ). These microscopic findings are subtle and may require multiple sections to identify in addition to clinical correlation. Dyskeratosis...
Images
Figure 1-3
Published: 01 December 2024
PRIMORDIA OF ADRENAL GLAND Figure 1-3 PRIMORDIA OF ADRENAL GLAND Schematic cross section of human embryo shows primordia of adrenal glands, which are located lateral to the base of the dorsal mesentery, separated from the gonadal primordium by the adrenal groove. (Fig. 1-3 from Lack EE More about this image found in PRIMORDIA OF ADRENAL GLAND Schematic cross section of human embryo shows p...
Images
Figure 1-5
Published: 01 December 2024
FETAL ADRENAL GLAND AND KIDNEY Figure 1-5 FETAL ADRENAL GLAND AND KIDNEY Coronal section of adrenal kidney and adjacent tissue from a fetus at approximately 11 weeks’ gestational age. The developing para-aortic sympathetic plexus has a close relationship with the medial and inferior aspects More about this image found in FETAL ADRENAL GLAND AND KIDNEY Coronal section of adrenal kidney and adjac...