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Figure 5-125

LATERAL RADICULAR CYST Secondary to the devitalized premolar is a draining...

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in Jaw > Tumors of the Upper Aerodigestive Tract, Ear, and Jaw
Published: 01 June 2025
LATERAL RADICULAR CYST Figure 5-125 LATERAL RADICULAR CYST Secondary to the devitalized premolar is a draining sinus track to the surface into which the clinician has inserted a gutta percha point. More about this image found in LATERAL RADICULAR CYST Secondary to the devitalized premolar is a draining...
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Figure 4-41

LYMPHANGIOMA OF THE DORSAL TONGUE The lesion presents as pebbly nodules (a...

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in Oral Cavity > Tumors of the Upper Aerodigestive Tract, Ear, and Jaw
Published: 01 June 2025
LYMPHANGIOMA OF THE DORSAL TONGUE Figure 4-41 LYMPHANGIOMA OF THE DORSAL TONGUE The lesion presents as pebbly nodules (arrows) with secondary hemorrhage. More about this image found in LYMPHANGIOMA OF THE DORSAL TONGUE The lesion presents as pebbly nodules (a...
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Figure 4-26

PROLIFERATIVE VERRUCOUS LEUKOPLAKIA A: Early lesions of PVL often have a c...

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in Oral Cavity > Tumors of the Upper Aerodigestive Tract, Ear, and Jaw
Published: 01 June 2025
” appearance. D: Secondary colonization with Candida (arrow) in PVL showing epithelial acanthosis and parakeratosis. More about this image found in PROLIFERATIVE VERRUCOUS LEUKOPLAKIA A: Early lesions of PVL often have a c...
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Figure 1-19

EXOPHYTIC SINONASAL PAPILLOMA A: Koilocytic changes, i.e., nuclear enlarge...

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in Sinonasal Cavity > Tumors of the Upper Aerodigestive Tract, Ear, and Jaw
Published: 01 June 2025
secondary to irritation. Most cases harbor low-risk human papillomavirus (HPV) as demonstrated by RNA in situ hybridization (inset). More about this image found in EXOPHYTIC SINONASAL PAPILLOMA A: Koilocytic changes, i.e., nuclear enlarge...
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Figure 4-24

ORAL CANDIDIASIS A: Chronic hyperplastic candidiasis on the midline poster...

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in Oral Cavity > Tumors of the Upper Aerodigestive Tract, Ear, and Jaw
Published: 01 June 2025
highlights the fungal hyphae and spores. C: Pseudoepitheliomatous hyperplasia associated with candidiasis. A neutrophilic microabscess is seen in the keratin (arrow). D: Moderate epithelial dysplasia with secondary colonization by Candida (inset). More about this image found in ORAL CANDIDIASIS A: Chronic hyperplastic candidiasis on the midline poster...
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Figure 6-22

TEFLON GRANULOMA A: Gross image of a laryngeal resection containing a firm...

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in Hypopharynx, Larynx, and Trachea > Tumors of the Upper Aerodigestive Tract, Ear, and Jaw
Published: 01 June 2025
TEFLON GRANULOMA Figure 6-22 TEFLON GRANULOMA A: Gross image of a laryngeal resection containing a firm white nodule secondary to injection of Teflon paste. B: Small irregularly shaped crystalline fragments of Teflon are within a dense fibrous stroma. C: The Teflon crystals embedded within More about this image found in TEFLON GRANULOMA A: Gross image of a laryngeal resection containing a firm...
Book Chapter

Oral Cavity

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-4
ISBN: 978-1-933477-61-9
... of the embryo. By the fifth week, the paired lateral maxillary processes and the frontonasal process surround the stomodeum and fuse, giving rise to the upper lip and the primary palate. The secondary palate is formed by the seventh week when two palatal shelves originating from the maxillary processes grow...
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Hypopharynx, Larynx, and Trachea

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-6
ISBN: 978-1-933477-61-9
... nodules can be very vascular, raising the possibility of granulation tissue secondary to trauma, but the histologic pattern of palisading histiocytes is not characteristic of granulation tissue. Infectious causes of necrotizing granulomatous inflammation are excluded using a combination of Grocott...
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Book Chapter

Neck

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-7
ISBN: 978-1-933477-61-9
... then be referred for germline testing as needed. Differential Diagnosis. Classic carotid body tumors and vagal paragangliomas are diagnosed easily based on their histologic features. Tumors with histologic variations and secondary changes, or those detected in a small biopsy, have a more significant differential...
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Sinonasal Cavity

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-1
ISBN: 978-1-933477-61-9
... straightforward. When secondary fibrin deposition is prominent, amyloidosis may be a consideration. Genuine amyloid is positive for Congo red with apple-green birefringence, in contrast to fibrin. In angiomatous polyps where recanalizing vessels are particularly striking, a vascular neoplasm such as angiosarcoma...
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Book Chapter

Jaw

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-5
ISBN: 978-1-933477-61-9
... within the jaws and gingiva for the remainder of the patients life. This epithelium is capable of producing a variety of true cysts, which are lined by odontogenic epithelium and are unique to the jaw. The inflammatory odontogenic cysts are those that arise secondary to a preexisting inflammatory process...
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Ear and Temporal Bone

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-8
ISBN: 978-1-933477-61-9
... bleeds, chondronecrosis, and secondary malignancy development ( 477 , 493 , 531 – 533 ). Management is individually tailored according to tumor stage, type, patient age, and other factors ( 495 ). ERMS is considered a systemic disease with prognosis dependent on age, anatomic site, and stage ( 494...
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Book Chapter

Nasopharynx

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-3
ISBN: 978-1-933477-61-9
... by NPC, patients present with unilateral serous otitis media, tinnitus, or hearing impairment. Patients with advanced disease and involvement of cranial nerves V or VI may experience facial nerve paresthesias or diplopia ( 53 ), and severe headache secondary to intracranial extension. Radiologic Findings...
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Book Chapter

Clinicopathologic Features of the Adrenal Cortex

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-03
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
.... The complexity of hormone regulation can also result in hyperplasia of the adrenal cortex, which is secondary to neoplasms in other body sites. In some clinical scenarios, the adrenal glands are resected to prevent hormone excess even when the primary pathology is elsewhere, and the pathologist must assess...
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Book Chapter

Other Adrenal Neoplasms and Tumor-Like Lesions

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-12
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
.... A peripheral rim of normal adrenal cortex is present at left. Occasionally, infarction or hemorrhage occurs along with secondary hematoma formation or fibrosis. Foci of ossification are occasionally present. The diagnosis is sometimes established by fine needle aspiration biopsy ( fig. 12-5 ) in conjunction...
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Adrenal Cortical Adenoma

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-05
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... by the diagnostic algorithmic approach, but in large population-based studies it represents up to 12 percent of cases, and is the second most frequent cause of secondary hypertension ( 10 ). Aldosterone-producing adenoma is not the only cause of primary hyperaldosteronism, and bilateral adrenal cortical nodular...
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Adrenal Cortical Nodular Diseases

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-04
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... ). In bilateral cases, the clinical distinction of primary from secondary forms is based on the detection of low plasma ACTH levels (if oversecretion of cortisol reaches sufficient levels). Bilateral primary causes include primary bilateral macronodular adrenal disease (PBMAD, previously known as primary...
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Neuroblastoma, Ganglioneuroblastoma, and Ganglioneuroma

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-11
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... tumors with a favorable prognosis. However, a second group of cases has also been described, in which watery diarrhea occurs after chemotherapeutic treatment of NBL, so-called secondary “VIP-omas,” which, in contrast to the first group, represent high-stage disease with a worse prognosis ( 32...
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Familial and Syndrome-Related Pheochromocytoma and Paraganglioma

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-10
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... of a syndrome or a coincidence. A prime example is immunohistochemical staining for SDHB showing that PitNET caused by loss of SDHB is rare ( 16 ). However, a hypothetical biologic consideration in these cases is whether a secondary effect of the hereditary mutation indirectly contributes to tumorigenesis...
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Book Chapter

Paraganglia and Paragangliomas

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-09
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... cytoplasmic bubbles and vacuoles that may mimic mucin droplets or signet ring cells (see fig. 9-23 ). Other potentially confounding morphologic changes are intratumoral congestion and hemorrhage secondary to ligation of blood vessels during surgery ( fig. 9-28 ), or necrosis from preoperative embolization...
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