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<span class="search-highlight">SECONDARY</span> PAGET DISEASE  A: Low-power image shows a large invasive lobular ...
Published: 01 January 2024
SECONDARY PAGET DISEASE Figure 13-16 SECONDARY PAGET DISEASE A: Low-power image shows a large invasive lobular carcinoma involving the dermis. This carcinoma extended up from the breast parenchyma. B: At high power, illustrating the direct extension of the tumor into the overlying epidermis. More about this image found in SECONDARY PAGET DISEASE A: Low-power image shows a large invasive lobular ...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-22
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
...Melanoma can affect the skin not only as a primary tumor, but also as a metastatic tumor deposit. Metastatic melanoma has not originated at the site where it is found, but represents secondary growth after intravascular, intralymphatic or potentially perivascular spread. CLINICAL FEATURES Melanoma...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-02
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
.... A. Marghoob, New York, NY) A CMN may develop a proliferative nodule (PN), which is a benign secondary cellular growth of melanocytes within a preexisting CMN. A PN may present as a papule, nodule, or plaque. It can be small, measuring a few millimeters, or large, measuring several centimeters...
Images
SQUAMOUS CELL CARCINOMA IN SITU  A: At low power, sheets of malignant-appea...
Published: 01 January 2024
SQUAMOUS CELL CARCINOMA IN SITU Figure 13-18 SQUAMOUS CELL CARCINOMA IN SITU A: At low power, sheets of malignant-appearing epithelioid cells involving the epidermis are apparent. B: At higher power, the cytologic atypia is better appreciated; the nuclei are large and pleomorphic; the cytoplasm ... More about this image found in SQUAMOUS CELL CARCINOMA IN SITU A: At low power, sheets of malignant-appea...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-12
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... in the distribution of melanocytes may be accompanied by irregular melanization (see figs. 12-2 , 12-9 ). Inflammation and fibrosis are common stromal changes (see fig. 12-6 ). Secondary epidermal changes include epidermal hyperplasia, effacement of rete ridges (“consumption of the epidermis”) (see fig. 12-2...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-18
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... (*) contrast with the bland fusiform and dendritic melanocytes of a blue nevus cell aggregate (arrow). Melanoma Associated with a Plaque-Type Blue Nevus. Plaque-type blue nevi can give rise to secondary benign cellular nodules as well as melanoma ( figs. 18-3 , 18-4 ) ( 9 ). The melanoma may be located...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-16
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... spreading, nodular, or acral) melanoma contains a partly desmoplastic component ( fig. 16-6 ). In another scenario, an otherwise pure DM contains one or several secondary hypercellular nodule(s) or areas of hypercellularity ( fig. 16-7 ). Hypercellular nodules may be located superficially or deep. Aside...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-07
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... stroma) or secondary epidermal changes, such as pseudoepitheliomatous epidermal hyperplasia. Spitz nevi can also be categorized by clinical appearance (macular, papular, polypoid, plaque-like), clinical settings (primary versus recurrent, solitary or agminated), and the presence of a dense inflammatory...
Images
ATRIAL SEPTAL DEFECT: <span class="search-highlight">SECONDARY</span> CARDIAC EFFECTS  There is marked cardiomega...
Published: 15 November 2023
ATRIAL SEPTAL DEFECT: SECONDARY CARDIAC EFFECTS Figure 35-8 ATRIAL SEPTAL DEFECT: SECONDARY CARDIAC EFFECTS There is marked cardiomegaly, with volume hypertrophy of right-sided chambers and annular dilatation of the tricuspid valve in a secundum defect (between arrows) in an elderly adult. The ca... More about this image found in ATRIAL SEPTAL DEFECT: SECONDARY CARDIAC EFFECTS There is marked cardiomega...
Images
CONGENITAL AORTIC STENOSIS  <span class="search-highlight">Secondary</span> effects on the left ventricle include...
Published: 15 November 2023
CONGENITAL AORTIC STENOSIS Figure 36-16 CONGENITAL AORTIC STENOSIS Secondary effects on the left ventricle include: concentric hypertrophy, in a child (A), hypertrophied myocytes with prominent lipofuscin pigment, in an older adult (B), focal myocyte disarray, in an adult (C) (this should not be ... More about this image found in CONGENITAL AORTIC STENOSIS Secondary effects on the left ventricle include...
Images
CONGENITAL SUBAORTIC STENOSIS  <span class="search-highlight">Secondary</span> effects on the left ventricle incl...
Published: 15 November 2023
CONGENITAL SUBAORTIC STENOSIS Figure 36-20 CONGENITAL SUBAORTIC STENOSIS Secondary effects on the left ventricle include concentric hypertrophy, with 539-g heart, and acute ischemic injury in both mitral papillary muscles (arrows), in an adult (A), marked myocyte hypertrophy (same patient as A) (... More about this image found in CONGENITAL SUBAORTIC STENOSIS Secondary effects on the left ventricle incl...
Images
PULMONARY STENOSIS  <span class="search-highlight">Secondary</span> effects on the right heart include: prominent...
Published: 15 November 2023
PULMONARY STENOSIS Figure 36-29 PULMONARY STENOSIS Secondary effects on the right heart include: prominent right ventricle and right atrium. The main pulmonary artery is narrowed at the valve level (arrows) and shows poststenotic dilatation distally (double-headed arrow), in an elderly adult (lef... More about this image found in PULMONARY STENOSIS Secondary effects on the right heart include: prominent...
Images
PULMONARY STENOSIS  <span class="search-highlight">Secondary</span> effects on the right heart include right vent...
Published: 15 November 2023
PULMONARY STENOSIS Figure 36-30 PULMONARY STENOSIS Secondary effects on the right heart include right ventricular hypertrophy with interstitial fibrosis of pericellular and replacement types (same patient as fig. 36-29 ). More about this image found in PULMONARY STENOSIS Secondary effects on the right heart include right vent...
Images
SUPRAVALVULAR PULMONARY STENOSIS  <span class="search-highlight">Secondary</span> effects in the right ventricle ...
Published: 15 November 2023
SUPRAVALVULAR PULMONARY STENOSIS Figure 36-37 SUPRAVALVULAR PULMONARY STENOSIS Secondary effects in the right ventricle include marked myocyte hypertrophy, in a child with coexistent supravalvular aortic stenosis. More about this image found in SUPRAVALVULAR PULMONARY STENOSIS Secondary effects in the right ventricle ...
Images
COARCTATION OF THE AORTA  <span class="search-highlight">Secondary</span> effects in the left ventricle include m...
Published: 15 November 2023
COARCTATION OF THE AORTA Figure 36-39 COARCTATION OF THE AORTA Secondary effects in the left ventricle include myocyte hypertrophy (left) and replacement-type interstitial fibrosis (right), in an adolescent with hypertension and an 800-g heart. More about this image found in COARCTATION OF THE AORTA Secondary effects in the left ventricle include m...
Images
PULMONARY ATRESIA WITH VENTRICULAR SEPTAL DEFECT: <span class="search-highlight">SECONDARY</span> CARDIOMEGALY  M...
Published: 15 November 2023
PULMONARY ATRESIA WITH VENTRICULAR SEPTAL DEFECT: SECONDARY CARDIOMEGALY Figure 37-16 PULMONARY ATRESIA WITH VENTRICULAR SEPTAL DEFECT: SECONDARY CARDIOMEGALY Myocyte hypertrophy and pericellular interstitial fibrosis are prominent and involve both the right ventricle (left) and left ventricle (r... More about this image found in PULMONARY ATRESIA WITH VENTRICULAR SEPTAL DEFECT: SECONDARY CARDIOMEGALY M...
Images
CONGENITALLY CORRECTED TRANSPOSITION OF THE GREAT ARTERIES: <span class="search-highlight">SECONDARY</span> CARDI...
Published: 15 November 2023
CONGENITALLY CORRECTED TRANSPOSITION OF THE GREAT ARTERIES: SECONDARY CARDIAC EFFECTS Figure 37-50 CONGENITALLY CORRECTED TRANSPOSITION OF THE GREAT ARTERIES: SECONDARY CARDIAC EFFECTS Left: There is marked hypertrophy of apical trabeculations in the left-sided right ventricle, in a middle-aged a... More about this image found in CONGENITALLY CORRECTED TRANSPOSITION OF THE GREAT ARTERIES: SECONDARY CARDI...
Images
DOUBLE INLET LEFT VENTRICLE: <span class="search-highlight">SECONDARY</span> CARDIAC EFFECTS  Hypertrophy and fib...
Published: 15 November 2023
DOUBLE INLET LEFT VENTRICLE: SECONDARY CARDIAC EFFECTS Figure 38-34 DOUBLE INLET LEFT VENTRICLE: SECONDARY CARDIAC EFFECTS Hypertrophy and fibrosis of the left ventricle are marked, in a young adolescent with an 875-g heart. More about this image found in DOUBLE INLET LEFT VENTRICLE: SECONDARY CARDIAC EFFECTS Hypertrophy and fib...
Images
EBSTEIN ANOMALY: <span class="search-highlight">SECONDARY</span> RIGHT ATRIAL CHANGES  Top: The wall is hypertrop...
Published: 15 November 2023
EBSTEIN ANOMALY: SECONDARY RIGHT ATRIAL CHANGES Figure 39-11 EBSTEIN ANOMALY: SECONDARY RIGHT ATRIAL CHANGES Top: The wall is hypertrophied, in a young adult. Bottom: There is mild diffuse endocardial fibroelastosis. (Both: from reduction right atrioplasty procedures.) More about this image found in EBSTEIN ANOMALY: SECONDARY RIGHT ATRIAL CHANGES Top: The wall is hypertrop...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-12
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... to the development of breast sarcomas ( 1 ). In addition to angiosarcoma, other types of sarcoma arising in the breast occur secondary to radiation therapy, including fibrosarcoma, leiomyosarcoma, and extraskeletal osteosarcoma ( 2 , 3 ). Clinical Features. Patients usually present with a hard, mobile, rapidly...