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Images
Figure 1-128
Published: 01 June 2025
SYNOVIAL SARCOMA Figure 1-128 SYNOVIAL SARCOMA A: Spindled cells with elongated, uniform nuclei are set in a collagenous stroma in this monophasic synovial sarcoma. B: In biphasic synovial sarcoma, in addition to the spindled cells, there are tumor glands lined by cuboidal cells. C: Poorly More about this image found in SYNOVIAL SARCOMA A: Spindled cells with elongated, uniform nuclei are set ...
Images
Figure 7-49
Published: 01 June 2025
SYNOVIAL SARCOMA Figure 7-49 SYNOVIAL SARCOMA A: Low-magnification view of a monophasic synovial sarcoma showing sheets of plump spindle cells with areas of fascicular growth. B: At higher magnification, the plump spindle cells have ovoid nuclei, which overlap each other and have, in this case More about this image found in SYNOVIAL SARCOMA A: Low-magnification view of a monophasic synovial sarcom...
Images
Figure 1-156
Published: 01 June 2025
ADAMANTINOMA-LIKE EWING SARCOMA Figure 1-156 ADAMANTINOMA-LIKE EWING SARCOMA A: The tumor grows as solid nests and cords of primitive-appearing cells. B: Scattered foci of abrupt squamous differentiation are sometimes seen. C, D: In contrast to conventional Ewing sarcoma, the adamantinoma-like More about this image found in ADAMANTINOMA-LIKE EWING SARCOMA A: The tumor grows as solid nests and cord...
Images
Figure 1-116
Published: 01 June 2025
FIBROSARCOMA Figure 1-116 FIBROSARCOMA This is a diagnosis of exclusion for a sarcoma showing a herringbone fascicular growth pattern, cellular atypia, and no evidence of specific mesenchymal differentiation. More about this image found in FIBROSARCOMA This is a diagnosis of exclusion for a sarcoma showing a herr...
Images
Figure 1-117
Published: 01 June 2025
UNDIFFERENTIATED PLEOMORPHIC SARCOMA Figure 1-117 UNDIFFERENTIATED PLEOMORPHIC SARCOMA A: Cells are markedly atypical and show no specific differentiation. B: Cases with prominent myxoid changes and prominent vessels are called myxofibrosarcoma. More about this image found in UNDIFFERENTIATED PLEOMORPHIC SARCOMA A: Cells are markedly atypical and sh...
Images
Figure 1-126
Published: 01 June 2025
BIPHENOTYPIC SINONASAL SARCOMA Figure 1-126 BIPHENOTYPIC SINONASAL SARCOMA A: The unencapsulated tumor often entraps the downward invaginations of surface epithelium. B: Haphazardly arranged fascicles surround dilated, thin-walled vessels. C: Alternating fascicles of spindled cells More about this image found in BIPHENOTYPIC SINONASAL SARCOMA A: The unencapsulated tumor often entraps t...
Images
Figure 1-127
Published: 01 June 2025
BIPHENOTYPIC SINONASAL SARCOMA Figure 1-127 BIPHENOTYPIC SINONASAL SARCOMA This tumor type invariably shows positivity for both S-100 protein (A) and SMA (B), although the extent of staining is variable. More about this image found in BIPHENOTYPIC SINONASAL SARCOMA This tumor type invariably shows positivity...
Images
Figure 1-157
Published: 01 June 2025
EWING SARCOMA Figure 1-157 EWING SARCOMA The tumor consists of uniform cells with clear cytoplasm and round nuclei containing powdery chromatin. More about this image found in EWING SARCOMA The tumor consists of uniform cells with clear cytoplasm and...
Images
Figure 2-46
Published: 01 June 2025
OROPHARYNGEAL FOLLICULAR DENDRITIC CELL SARCOMA Figure 2-46 OROPHARYNGEAL FOLLICULAR DENDRITIC CELL SARCOMA Low magnification view shows vaguely nodular sheets of cells interspersed with some associated mature lymphocytes. More about this image found in OROPHARYNGEAL FOLLICULAR DENDRITIC CELL SARCOMA Low magnification view sho...
Images
Figure 2-47
Published: 01 June 2025
OROPHARYNGEAL FOLLICULAR DENDRITIC CELL SARCOMA Figure 2-47 OROPHARYNGEAL FOLLICULAR DENDRITIC CELL SARCOMA High magnification view shows the tumor cells in sheets with round to ovoid nuclei, small nucleoli, scattered multinucleated cells, irregular nuclear contours, and interspersed mature More about this image found in OROPHARYNGEAL FOLLICULAR DENDRITIC CELL SARCOMA High magnification view sh...
Images
Figure 5-35
Published: 01 June 2025
ODONTOGENIC SARCOMA (OS) Figure 5-35 ODONTOGENIC SARCOMA (OS) Poorly marginated osteolytic OS of right posterior mandible. More about this image found in ODONTOGENIC SARCOMA (OS) Poorly marginated osteolytic OS of right posterio...
Images
Figure 5-36
Published: 01 June 2025
ODONTOGENIC SARCOMA Figure 5-36 ODONTOGENIC SARCOMA A–C: Hypercellular embryonal mesenchymal stroma (A) with significant cytologic atypia and increased mitoses on higher magnification (B,C). More about this image found in ODONTOGENIC SARCOMA A–C: Hypercellular embryonal mesenchymal stroma (A) wi...
Images
Figure 7-16
Published: 01 June 2025
FOLLICULAR DENDRITIC CELL SARCOMA Figure 7-16 FOLLICULAR DENDRITIC CELL SARCOMA A,B: Groups of loosely cohesive, atypical histiocytoid cells (A) are immunohistochemically positive for CD23 (B). More about this image found in FOLLICULAR DENDRITIC CELL SARCOMA A,B: Groups of loosely cohesive, atypica...
Images
Figure 7-50
Published: 01 June 2025
SYNOVIAL SARCOMA Figure 7-50 SYNOVIAL SARCOMA A,B: The aspirates are cellular and show loosely cohesive groups of cells with irregular edges. Spindle cells are uniform, with plump oval nuclei and rare mitoses. (Papanicolaou stain) More about this image found in SYNOVIAL SARCOMA A,B: The aspirates are cellular and show loosely cohesive...
Images
Figure 5-195
Published: 01 June 2025
MESENCHYMAL CHONDROSARCOMA Figure 5-195 MESENCHYMAL CHONDROSARCOMA A: The perivascular, hemangiopericytoma-like pattern of primitive round to spindled cells of mesenchymal chondrosarcoma may mimic Ewing sarcoma. B: Strong and diffuse membrane positivity of CD99 in the small cells. More about this image found in MESENCHYMAL CHONDROSARCOMA A: The perivascular, hemangiopericytoma-like pa...
Images
Figure 7-53
Published: 01 June 2025
is extremely rare in the head and neck. This typical chordoma in the upper right is juxtaposed to a high-grade, spindled and pleomorphic sarcoma in the lower aspect. More about this image found in CHORDOMA A: Chondroid chordoma can have a basophilic matrix with lobulatio...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-7
ISBN: 978-1-933477-61-9
... with true vascular neoplasms, but close examination shows that the tumor cells are between the vessels, rather than lining them. Immunohistochemistry easily resolves this given the lack of neuroendocrine markers in vascular neoplasms. Granular cell tumors and alveolar soft part sarcoma can be considered...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-1
ISBN: 978-1-933477-61-9
... of angiofibroma are positive, while antrochoanal polyps are negative. The bizarrely atypical stromal cells of some sinonasal inflammatory polyps can, on occasion, raise the possibility of a sarcoma such as embryonal rhabdomyosarcoma ( 9 ). The atypical stromal cells of benign polyps are randomly distributed...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-2
ISBN: 978-1-933477-61-9
..., immunohistochemical markers such as cytokeratin AE1/AE3, p40, and CD45 easily differentiate carcinomas from lymphomas ( 128 – 130 ). The treatment and behavior of the various hematolymphoid neoplasms is highly variable and beyond the scope of this chapter ( 129 , 130 , 138 , 140 ). Follicular Dendritic Cell Sarcoma...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-8
ISBN: 978-1-933477-61-9
... course, although local lymph node metastases may develop. The tumor has been termed paradoxical fibrosarcoma, pseudosarcoma, superficial malignant fibrous histiocytoma, dermal undifferentiated pleomorphic sarcoma, and superficial pleomorphic sarcoma, but atypical fibroxanthoma is the diagnostic category...