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Figure 3-22
Published: 01 June 2025
MALIGNANT SALIVARY GLAND TUMORS OF THE NASOPHARYNX Figure 3-22 MALIGNANT SALIVARY GLAND TUMORS OF THE NASOPHARYNX Adenoid cystic carcinoma and mucoepidermoid carcinoma are the two most common, albeit rare, specific subtypes of salivary gland cancer in the nasopharynx. A: The classic cribriform More about this image found in MALIGNANT SALIVARY GLAND TUMORS OF THE NASOPHARYNX Adenoid cystic carcinom...
Images
Figure 3-23
Published: 01 June 2025
NASOPHARYNGEAL SALIVARY GLAND ANLAGE TUMOR Figure 3-23 NASOPHARYNGEAL SALIVARY GLAND ANLAGE TUMOR A: Low-magnification view shows the polypoid tumor. B–D: Branching squamous elements (B) form a significant component of the tumor and show close approximation to the overlying surface epithelium More about this image found in NASOPHARYNGEAL SALIVARY GLAND ANLAGE TUMOR A: Low-magnification view shows...
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Figure 3-24
Published: 01 June 2025
NASOPHARYNGEAL SALIVARY GLAND ANLAGE TUMOR Figure 3-24 NASOPHARYNGEAL SALIVARY GLAND ANLAGE TUMOR A–C: The tumor is composed of a combination of branching squamous (A), glandular (B), and tubular (C) elements. More about this image found in NASOPHARYNGEAL SALIVARY GLAND ANLAGE TUMOR A–C: The tumor is composed of a...
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Figure 1-179
Published: 01 June 2025
NK/T-CELL LYMPHOMA Figure 1-179 NK/T-CELL LYMPHOMA A: A minor mucoserous gland is partly destroyed by atypical lymphoid cells. B: A sheet-like but polymorphous inflammatory infiltrate. C: Minor salivary gland destruction with a slightly atypical lymphoid population. D: The lymphoid cells More about this image found in NK/T-CELL LYMPHOMA A: A minor mucoserous gland is partly destroyed by atyp...
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Figure 4-65
Published: 01 June 2025
and eosinophilic cytoplasm are commonly seen in minor salivary gland pleomorphic adenomas. D: Myoepithelial-rich pleomorphic adenoma with a chondroid matrix. More about this image found in PLEOMORPHIC ADENOMA A: Characteristic low-power image shows varying patter...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-3
ISBN: 978-1-933477-61-9
... of the nasopharynx, and is an area that contains various embryologic remnants that on occasion give rise to nasopharyngeal masses ( 5 ). The torus tubarius and its recently described minor salivary gland tissue and nearby pharyngeal recess known as Rosenmuller fossa are present within the nasopharynx posterior...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-4
ISBN: 978-1-933477-61-9
... and other causes of chronic irritation can result in keratinization of nonkeratinized mucosa. The lamina propria is composed of connective tissue supporting blood vessels, lymphatics, nerves, and minor salivary glands. HISTOLOGY OF THE ORAL CAVITY Figure 4-2 HISTOLOGY OF THE ORAL CAVITY A: Nonkeratinized...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-2
ISBN: 978-1-933477-61-9
... ) reported that the 48 patients with HPV DNA immunohistochemical-negative tumors had a median survival period of 20 months while the 26 patients with HPV DNA-positive cancers (most of which were oropharyngeal primaries) had a median survival period of only 15 months ( 81 ). SALIVARY GLAND TUMORS...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-6
ISBN: 978-1-933477-61-9
... of neuroendocrine, salivary, and melanocytic differentiation, such as chromogranin, synaptophysin, muscle-specific actin, and glial fibrillary acidic protein, are negative. Somewhat confusingly, SOX10 is diffusely positive in BSCC and thus is a potential pitfall ( 149 ). Molecular Genetic Findings. Aside from...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-1
ISBN: 978-1-933477-61-9
...) is a malignant, gland-forming neoplasm that lacks intestinal differentiation and is not better diagnosed as a salivary-type adenocarcinoma. It is subdivided into low-grade (LG) and high-grade (HG) tumors. General Features. LG SNAC is uncommon, and arises in a broad age range with no sex predilection. HG SNAC...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-8
ISBN: 978-1-933477-61-9
..., mitoses, and apoptotic figures as seen in BCC. Solid BCCs may be confused with adenoid cystic carcinoma (skin or salivary gland primaries), although adenoid cystic carcinoma is not connected with the overlying epidermis and often shows cribriform areas with perineural invasion. The prognosis is usually...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-5
ISBN: 978-1-933477-61-9
... carcinoma isn’t the result of direct extension from another adjacent anatomic site. Central epithelial malignancies with significant ameloblastic differentiation are diagnosed as ACs and lesions with glandular differentiation are not PIOCs, but rather metastatic lesions or primary salivary gland neoplasms...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-7
ISBN: 978-1-933477-61-9
... and neck pathology practice, and patients characteristically present with an enlarging neck mass as the first manifestation of the metastatic carcinoma. While 80 to 85 percent of these metastatic carcinomas are SCCs, other types of carcinoma occur including salivary gland carcinomas, thyroid gland...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-03
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... is an early feature of Cushing syndrome. Assays must be established to measure free cortisol, since the amount of cortisol-binding globulin (CBG) can also vary based on other conditions. Because the concentration of cortisol in saliva is in equilibrium with free cortisol in plasma, measurements of salivary...
Images
Figure 9-3
Published: 01 September 2024
LYMPHOEPITHELIAL CYST Figure 9-3 LYMPHOEPITHELIAL CYST Salivary gland with proliferating precystic epithelium and infiltrating lymphocytes. (Courtesy of the Joint Pathology Center [JPC]) More about this image found in LYMPHOEPITHELIAL CYST Salivary gland with proliferating precystic epitheli...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-27
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... meal to perpetuate the cycle. Fertilization of gametes takes place in the tick gut, forming ookinetes that migrate to the tick’s salivary gland. Here the organisms undergo sporogony to form infectious sporozoites, which are then injected into a new host. Humans are considered accidental hosts because...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-08
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... NK-cell leukemia Nasopharyngeal carcinoma Gastric adenocarcinoma Lymphoepithelioma-like carcinomas of salivary glands EBV-associated smooth muscle tumors tumors Multiple sclerosis Sjorgen syndrome Systemic lupus erythematosus Rheumatoid arthritis Chronic inflammatory bowel disease Table 8-3 HHV8...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-25
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... before migrating to the salivary gland as epimastigotes. Here there is further multiplication and transformation into infective forms of the parasite (metacyclic trypomastigotes). The latter is then inoculated into the human host during a subsequent blood meal. In the host, these infective forms again...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-03
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... spreads in the CNS, there is also centrifugal spread with systemic viral dissemination to multiple organs, including lymph nodes and salivary glands. RAV uses several mechanisms to evade the host immune response, including suppression of interferon production and its intraneuronal location beyond...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-09
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... dendritic cells when present in large amounts. D: Spleen in early HIV infection, with enlarged lymphoid follicles. E: Same case as in D, showing spleen cytology specimen stained with HIVp24 to demonstrate heavy viral load. LYMPHOEPITHELIAL CYST Figure 9-3 LYMPHOEPITHELIAL CYST Salivary gland...