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SUPERFICIAL SPREADING MELANOMA ARISING IN ASSOCIATION WITH A NEVUS  A: Asym...
Published: 01 February 2024
SUPERFICIAL SPREADING MELANOMA ARISING IN ASSOCIATION WITH A NEVUS Figure 20-1 SUPERFICIAL SPREADING MELANOMA ARISING IN ASSOCIATION WITH A NEVUS A: Asymmetric silhouette of the lesion of a teenager shows an ulcerated nodular growth on the right side and a plaque lesion of a compound nevus on the left. B: Compound melanocytic nevus with bland cytologic features. C: In situ and invasive melanoma are characterized by architectural disorder and nuclear atypia. D: The primary invasive melanoma contains sheets of atypical melanocytes, some of which are in mitosis. E: Metastatic melanoma in the sentinel lymph node. F: The tumor cells homogenously express BRAF V600E. More about this image found in SUPERFICIAL SPREADING MELANOMA ARISING IN ASSOCIATION WITH A NEVUS A: Asym...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-19
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... other tests. For example, several studies have identified homozygous deletions of 9p21 (p16/CDKN2A) in spitzoid melanomas ( 12 ). While the detection these aberrations can help support a suspected diagnosis of melanoma in the right histopathologic and molecular driver context, they are neither necessary...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-20
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... suprabasilar melanocytes ( 23 , 24 ). SUPERFICIAL SPREADING MELANOMA ARISING IN ASSOCIATION WITH A NEVUS Figure 20-1 SUPERFICIAL SPREADING MELANOMA ARISING IN ASSOCIATION WITH A NEVUS A: Asymmetric silhouette of the lesion of a teenager shows an ulcerated nodular growth on the right side and a plaque lesion...
Images
SPECIMEN RADIOGRAPH OF CORE NEEDLE BIOPSY SPECIMEN  A: Microcalcifications ...
Published: 01 January 2024
SPECIMEN RADIOGRAPH OF CORE NEEDLE BIOPSY SPECIMEN Figure 15-2 SPECIMEN RADIOGRAPH OF CORE NEEDLE BIOPSY SPECIMEN A: Microcalcifications are present in the sample at the lower right. Notice also the suggestion of a mass associated with the calcifications. B: The pathology demonstrated a fibroade... More about this image found in SPECIMEN RADIOGRAPH OF CORE NEEDLE BIOPSY SPECIMEN A: Microcalcifications ...
Images
MAMMARY HAMARTOMA  This excisional biopsy depicts a well-circumscribed mass...
Published: 01 January 2024
MAMMARY HAMARTOMA Figure 5-44 MAMMARY HAMARTOMA This excisional biopsy depicts a well-circumscribed mass of normal breast tissue, with admixed adipose tissue (border at top right of image). These features, in the context of a palpable or image-detected mass, are compatible with a mammary hamartom... More about this image found in MAMMARY HAMARTOMA This excisional biopsy depicts a well-circumscribed mass...
Images
ANGIOSARCOMA  This image illustrates the frequent finding of varied pattern...
Published: 01 January 2024
ANGIOSARCOMA Figure 11-24 ANGIOSARCOMA This image illustrates the frequent finding of varied patterns of differentiation within the same lesion. On the left side of the image, the angiosarcoma could be classified as well-differentiated; on the right side of the image, the growth pattern is solid ... More about this image found in ANGIOSARCOMA This image illustrates the frequent finding of varied pattern...
Images
BIOPSY CLIP SITE  In this scanning magnification image, a positive lymph no...
Published: 01 January 2024
BIOPSY CLIP SITE Figure 14-3 BIOPSY CLIP SITE In this scanning magnification image, a positive lymph node is seen on the left, and on the right is histologic evidence of the biopsy clip site, which must be identified and documented in any case in which preoperative lymph node sampling has occurre... More about this image found in BIOPSY CLIP SITE In this scanning magnification image, a positive lymph no...
Images
PAPILLARY LESION WITH INFARCTION  A: At low power, an area of papillary duc...
Published: 01 January 2024
PAPILLARY LESION WITH INFARCTION Figure 7-8 PAPILLARY LESION WITH INFARCTION A: At low power, an area of papillary ductal carcinoma in situ (DCIS) is apparent at the right of the field, beside which is a needle biopsy tract with an adjacent area of necrosis. B: At higher power, the “ghosts” of f... More about this image found in PAPILLARY LESION WITH INFARCTION A: At low power, an area of papillary duc...
Images
MUCOCELE-LIKE LESION WITH ATYPIA  A: At intermediate power, this mucocele-l...
Published: 01 January 2024
MUCOCELE-LIKE LESION WITH ATYPIA Figure 8-53 MUCOCELE-LIKE LESION WITH ATYPIA A: At intermediate power, this mucocele-like lesion has areas of flat epithelial atypia (right of field). Strips and micropapillary fragments of epithelium have become detached. B: High-power view of the detached fragm... More about this image found in MUCOCELE-LIKE LESION WITH ATYPIA A: At intermediate power, this mucocele-l...
Images
PLEOMORPHIC WITH ADJACENT CLASSIC LOBULAR CARCINOMA IN SITU  A: Intermediat...
Published: 01 January 2024
PLEOMORPHIC WITH ADJACENT CLASSIC LOBULAR CARCINOMA IN SITU Figure 4-17 PLEOMORPHIC WITH ADJACENT CLASSIC LOBULAR CARCINOMA IN SITU A: Intermediate-power image shows adjacent areas of classic (right side of image) and pleomorphic LCIS (central and left side of image). B: High power shows the lar... More about this image found in PLEOMORPHIC WITH ADJACENT CLASSIC LOBULAR CARCINOMA IN SITU A: Intermediat...
Images
JUVENILE PAPILLOMATOSIS  A: Low-power view demonstrates variably sized cyst...
Published: 01 January 2024
JUVENILE PAPILLOMATOSIS Figure 9-1 JUVENILE PAPILLOMATOSIS A: Low-power view demonstrates variably sized cysts, foci of apocrine metaplasia (lower left), fibroadenomatous change (upper right), micropapillomas, and adenosis. B: Intermediate power of the areas of adenosis, cysts, and micropapillom... More about this image found in JUVENILE PAPILLOMATOSIS A: Low-power view demonstrates variably sized cyst...
Images
PHYLLODES TUMOR  A: This core needle biopsy specimen highlights the extreme...
Published: 01 January 2024
PHYLLODES TUMOR Figure 5-37 PHYLLODES TUMOR A: This core needle biopsy specimen highlights the extreme variability that can be seen in phyllodes tumor, with the area on the right bearing greater resemblance to fibroadenoma, and that on the lower left, malignant phyllodes tumor. B,C: High power o... More about this image found in PHYLLODES TUMOR A: This core needle biopsy specimen highlights the extreme...
Images
DUCTAL CARCINOMA IN SITU: HIGH NUCLEAR GRADE WITH MICROINVASION  A: Interme...
Published: 01 January 2024
DUCTAL CARCINOMA IN SITU: HIGH NUCLEAR GRADE WITH MICROINVASION Figure 3-27 DUCTAL CARCINOMA IN SITU: HIGH NUCLEAR GRADE WITH MICROINVASION A: Intermediate-power view illustrates high nuclear grade DCIS with involvement of lobules (top of field). The inflammatory cell infiltrate is prominent. Sin... More about this image found in DUCTAL CARCINOMA IN SITU: HIGH NUCLEAR GRADE WITH MICROINVASION A: Interme...
Images
LOBULAR CARCINOMA IN SITU AND LOW NUCLEAR GRADE DUCTAL CARCINOMA IN SITU AN...
Published: 01 January 2024
LOBULAR CARCINOMA IN SITU AND LOW NUCLEAR GRADE DUCTAL CARCINOMA IN SITU AND/OR ATYPICAL DUCTAL HYPERPLASIA (SOLID PATTERN) Figure 4-11 LOBULAR CARCINOMA IN SITU AND LOW NUCLEAR GRADE DUCTAL CARCINOMA IN SITU AND/OR ATYPICAL DUCTAL HYPERPLASIA (SOLID PATTERN) These can be difficult to distinguish... More about this image found in LOBULAR CARCINOMA IN SITU AND LOW NUCLEAR GRADE DUCTAL CARCINOMA IN SITU AN...
Images
PAPILLOMA WITH DUCTAL CARCINOMA IN SITU  A: Low-power view of a sclerosed p...
Published: 01 January 2024
PAPILLOMA WITH DUCTAL CARCINOMA IN SITU Figure 7-18 PAPILLOMA WITH DUCTAL CARCINOMA IN SITU A: Low-power view of a sclerosed papilloma. B: At intermediate power, the significant cytologic atypia of some of the epithelial cells is apparent. C: At high power, cells with abundant eosinophilic cyto... More about this image found in PAPILLOMA WITH DUCTAL CARCINOMA IN SITU A: Low-power view of a sclerosed p...
Images
MALIGNANT PHYLLODES TUMOR  A: At low power, this core needle biopsy appears...
Published: 01 January 2024
MALIGNANT PHYLLODES TUMOR Figure 5-36 MALIGNANT PHYLLODES TUMOR A: At low power, this core needle biopsy appears to be composed entirely of spindle cells. The lesion is hypercellular. The tissue fragment at upper right has a focus of benign-appearing epithelium (arrow). B: Higher power shows the... More about this image found in MALIGNANT PHYLLODES TUMOR A: At low power, this core needle biopsy appears...
Images
LOBULAR CARCINOMA IN SITU AND ATYPICAL DUCTAL HYPERPLASIA (ADH)  Not infreq...
Published: 01 January 2024
LOBULAR CARCINOMA IN SITU AND ATYPICAL DUCTAL HYPERPLASIA (ADH) Figure 4-8 LOBULAR CARCINOMA IN SITU AND ATYPICAL DUCTAL HYPERPLASIA (ADH) Not infrequently lobular neoplasia (LCIS or ALH) coexists with other lesions in the low-grade breast neoplasia family, as in this example of ADH and LCIS. In ... More about this image found in LOBULAR CARCINOMA IN SITU AND ATYPICAL DUCTAL HYPERPLASIA (ADH) Not infreq...
Images
BIOPSY SITE WITH DISPLACED EPITHELIUM  A: A benign proliferative lesion wit...
Published: 01 January 2024
BIOPSY SITE WITH DISPLACED EPITHELIUM Figure 2-7 BIOPSY SITE WITH DISPLACED EPITHELIUM A: A benign proliferative lesion with adjacent biopsy site and displaced epithelial elements. B: High power shows the epithelial nests and glands embedded in a reactive, spindle cell stroma with admixed histio... More about this image found in BIOPSY SITE WITH DISPLACED EPITHELIUM A: A benign proliferative lesion wit...
Images
METAPLASTIC CARCINOMA ARISING IN MICROGLANDULAR ADENOSIS  A: At low power, ...
Published: 01 January 2024
METAPLASTIC CARCINOMA ARISING IN MICROGLANDULAR ADENOSIS Figure 6-20 METAPLASTIC CARCINOMA ARISING IN MICROGLANDULAR ADENOSIS A: At low power, there are small glands containing secretions distributed across the central portion of the field. A cellular proliferation can be appreciated at the upper... More about this image found in METAPLASTIC CARCINOMA ARISING IN MICROGLANDULAR ADENOSIS A: At low power, ...
Images
PULMONARY HYPERTENSION: <span class="search-highlight">RIGHT</span> VENTRICULAR HYPERTROPHY  Massive <span class="search-highlight">right</span> ventri...
Published: 15 November 2023
PULMONARY HYPERTENSION: RIGHT VENTRICULAR HYPERTROPHY Figure 20-7 PULMONARY HYPERTENSION: RIGHT VENTRICULAR HYPERTROPHY Massive right ventricular hypertrophy in the setting of pulmonary hypertension (pulmonary veno-occlusive disease-associated). More about this image found in PULMONARY HYPERTENSION: RIGHT VENTRICULAR HYPERTROPHY Massive right ventri...