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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-02
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... . Am J Med Genet A 2016 ; 170 : 2248 - 60 . 59. Longardt AC , Nonnenmacher A , Graul-Neumann L , et al . Fetal intracardiac rhabdomyoma in Beckwith-Wiedemann syndrome . J Clin Ultrasound 2014 ; 42 : 569 - 73 . 60. Caza T , Manwaring J , Riddell J...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch43
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
...Table 43-1 DIAGNOSIS OF TUBEROUS SCLEROSIS COMPLEX a Major Diagnostic Features b Cardiac rhabdomyoma Hypomelanotic macules (≥3 in number, each ≥5 mm) Angiofibromas (≥3) Ungual fibromas (≥2) Shagreen patch Multiple retinal hamartomas...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch47
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
...ADULT CELLULAR RHABDOMYOMA Figure 47-1 ADULT CELLULAR RHABDOMYOMA Contrast-enhanced axial computerized tomography (CT) demonstrating a homogeneously enhancing, 2-cm ovoid mass (black arrow) attached to the ventricular septum and protruding into the right ventricular chamber. ADULT CELLULAR...
Images
Published: 15 November 2023
CARDIAC RHABDOMYOMA: INVOLUTED Figure 43-8 CARDIAC RHABDOMYOMA: INVOLUTED Involuted or regressed cardiac rhabdomyomas may have the gross (left) and histologic (right) appearance of fat. More about this image found in CARDIAC RHABDOMYOMA: INVOLUTED Involuted or regressed cardiac rhabdomyomas...
Images
Published: 15 November 2023
CARDIAC RHABDOMYOMA Figure 43-4 CARDIAC RHABDOMYOMA The tumor is a lobulated, yellow-tan, well-circumscribed mass with a firm consistency. More about this image found in CARDIAC RHABDOMYOMA The tumor is a lobulated, yellow-tan, well-circumscrib...
Images
Published: 15 November 2023
CARDIAC RHABDOMYOMA: ECHOCARDIOGRAPHY Figure 43-1 CARDIAC RHABDOMYOMA: ECHOCARDIOGRAPHY Multiple tumors (yellow asterisks) are seen in both the left and right ventricles. More about this image found in CARDIAC RHABDOMYOMA: ECHOCARDIOGRAPHY Multiple tumors (yellow asterisks) a...
Images
Published: 15 November 2023
ADULT CELLULAR RHABDOMYOMA Figure 47-3 ADULT CELLULAR RHABDOMYOMA At low-power magnification, the tumor consists of a cellular polypoid mass arising from a small pedicle with normal myocardium. More about this image found in ADULT CELLULAR RHABDOMYOMA At low-power magnification, the tumor consists ...
Images
Published: 15 November 2023
ADULT CELLULAR RHABDOMYOMA Figure 47-2 ADULT CELLULAR RHABDOMYOMA This bivalved surgically resected mass, measuring approximately 2 cm, exhibits a smooth surface with a homogeneous tan-yellow appearance. More about this image found in ADULT CELLULAR RHABDOMYOMA This bivalved surgically resected mass, measuri...
Images
Published: 15 November 2023
ADULT CELLULAR RHABDOMYOMA Figure 47-4 ADULT CELLULAR RHABDOMYOMA Some cells have abundant eosinophilic cytoplasm, almost resembling rhabdomyoblasts. In contrast to rhabdomyosarcoma, there is little atypia or mitotic activity, and necrosis is absent. More about this image found in ADULT CELLULAR RHABDOMYOMA Some cells have abundant eosinophilic cytoplasm...
Images
Published: 15 November 2023
ADULT CELLULAR RHABDOMYOMA Figure 47-5 ADULT CELLULAR RHABDOMYOMA Left: The tumor is cellular, with subtle open vasculature. Right: The relative paucity of cytoplasm and overall cellularity separate this lesion from hamartoma of mature cardiac myocytes. More about this image found in ADULT CELLULAR RHABDOMYOMA Left: The tumor is cellular, with subtle open v...
Images
Published: 15 November 2023
RHABDOMYOMA (“SPIDER”) CELLS Figure 43-5 RHABDOMYOMA (“SPIDER”) CELLS Left: Abundant intracellular glycogen imparts a striking vacuolated appearance. Right: Radial cytoplasmic strands extending form the nucleus to the sarcoplasmic membrane impart the appearance of a spider. More about this image found in RHABDOMYOMA (“SPIDER”) CELLS Left: Abundant intracellular glycogen imparts...
Images
Published: 15 November 2023
CARDIAC RHABDOMYOMA Figure 43-7 CARDIAC RHABDOMYOMA Left: Low-power view shows a sharp border between tumor and adjacent normal myocardium. Right: The tumor itself is variably cellular with only scattered true “spider” cells present. More about this image found in CARDIAC RHABDOMYOMA Left: Low-power view shows a sharp border between tumo...
Images
Published: 15 November 2023
CARDIAC RHABDOMYOMA: NONOBSTRUCTIVE Figure 43-3 CARDIAC RHABDOMYOMA: NONOBSTRUCTIVE Left: A single tumor (yellow arrowhead) involves the ventricular septum. Right: Multiple nonobstructive tumors (yellow arrows) stud the right ventricular (RV) and right atrial (RA) myocardium. More about this image found in CARDIAC RHABDOMYOMA: NONOBSTRUCTIVE Left: A single tumor (yellow arrowhead...
Images
Published: 15 November 2023
ADULT CELLULAR RHABDOMYOMA Figure 47-1 ADULT CELLULAR RHABDOMYOMA Contrast-enhanced axial computerized tomography (CT) demonstrating a homogeneously enhancing, 2-cm ovoid mass (black arrow) attached to the ventricular septum and protruding into the right ventricular chamber. More about this image found in ADULT CELLULAR RHABDOMYOMA Contrast-enhanced axial computerized tomography...
Images
Published: 15 November 2023
CARDIAC RHABDOMYOMA Figure 43-6 CARDIAC RHABDOMYOMA At high-power microscopy, plump eosinophilic central bodies are seen throughout the tumor (left), but not all tumor cells have the central cellular body, making some of the tumor look a bit like adipose tissue (right). More about this image found in CARDIAC RHABDOMYOMA At high-power microscopy, plump eosinophilic central b...
Images
Published: 15 November 2023
CARDIAC RHABDOMYOMA Figure 43-2 CARDIAC RHABDOMYOMA A,B: Multiple, large, obstructive (black asterisks) and nonobstructive (black arrowheads) tumors are seen from the right anterior oblique (A) and the left ventricular (LV) long-axis (B) views. C,D: Large lobulated masses (black asterisks) are s... More about this image found in CARDIAC RHABDOMYOMA A,B: Multiple, large, obstructive (black asterisks) an...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch42
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... of cardiac tumors in children by electron-beam computed tomography: rhabdomyoma and fibroma . Circ J 2005 ; 69 : 1352 - 6 . 26. Numata K , Tomita H . [ Cardiac fibroma in an infant: comparison of echocardiographic findings with cardiac rhabdomyoma ]. J Cardiol 1994 ; 24 : 71 - 6...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch45
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... germline genetic underpinnings ( 15 ). In this sense, it is not unlike cardiac rhabdomyoma and its association with tuberous sclerosis. The cell of origin of conduction system hamartoma is a Purkinje-type cardiac myocyte that was once thought to be a histiocytic proliferation by histomorphology ( 16...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch46
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... with tuberous sclerosis, including several that have been posited (by imaging) to possibly be angiomyolipoma ( 8 ). Given the propensity of rhabdomyomas to regress and the fact that these fatty lesions occur in places where rhabdomyomas are seen, it seems plausible that these could simply represent regressed...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch25
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... are more likely to die suddenly and show findings of underlying cardiac disease, which in children include various congenital heart diseases, cardiac rhabdomyoma, and cardiomyopathy ( 28 ). Structural heart disease in adults, including ischemic heart disease, is usually considered incidental to WPW...
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