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Book Chapter

Familial and Syndrome-Related Pheochromocytoma and Paraganglioma

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-10
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... angiomas of the cerebellum and spine in 1927. The association of these two disorders led to the term von Hippel-Lindau disease. VHL is typically characterized by retinal angiomas; central nervous system hemangioblastomas; hemangiomas of the adrenal gland, liver, and lung; and cysts in the kidney, pancreas...
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Images
Figure 16-2

INFECTIVE ENDOCARDITIS Ocular involvement shows Roth spots on fundoscopic ...

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in Heart > Pathology of Non-Helminth Infectious Diseases
Published: 01 September 2024
INFECTIVE ENDOCARDITIS Figure 16-2 INFECTIVE ENDOCARDITIS Ocular involvement shows Roth spots on fundoscopic examination. Note the round to flame-shaped retinal hemorrhage with pale center (arrow). (Courtesy of the Centers for Disease Control and Prevention [CDC] Public Health Image Library More about this image found in INFECTIVE ENDOCARDITIS Ocular involvement shows Roth spots on fundoscopic ...
Book Chapter

Heart

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-16
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... INFECTIVE ENDOCARDITIS Ocular involvement shows Roth spots on fundoscopic examination. Note the round to flame-shaped retinal hemorrhage with pale center (arrow). (Courtesy of the Centers for Disease Control and Prevention [CDC] Public Health Image Library [PHIL]) INFECTIVE ENDOCARDITIS Figure 16-4...
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Book Chapter

Systemic Infections

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-27
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... jaundice, hepatosplenomegaly, pharyngeal erythema, and a variety of ocular findings (including retinal hemorrhages). Splenic rupture may complicate splenomegaly ( fig. 27-8 ) ( 17 ). Laboratory findings include hemolytic anemia, thrombocytopenia, increased liver enzymes and creatinine, hemoglobinuria...
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Book Chapter

Skin and Soft Tissue

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-06
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... on the region/nerves affected) include keratitis, retinal necrosis, and meningitis if the ophthalmic nerve was affected. Vasculopathy is a further complication and can result in cerebrovascular lesions (stroke) and myocardial infarction. The clinical features of HSV1, 2, and VZV infection are very...
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Book Chapter

Central Nervous System

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-25
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... with congenital abnormalities, particularly if they involve the brain and eye. These abnormalities include hydrocephalus, brain and retinal calcifications, seizures, mental retardation, psychomotor deficiencies, deafness, microphthalmia, strabismus, increased intraocular pressure, cataracts, optic neuritis...
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Book Chapter

Sexually Transmitted and Urogenital Infections

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-09
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... tubulointerstitial nephritis, hemorrhagic cystitis, and ureteric stenosis. As a transplanted kidney lacks normal innervation, ureteric stenosis is not associated with typical symptoms in this population. In addition to urinary tract involvement, BKV can also disseminate to other organs, causing retinitis (mostly...
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Book Chapter

Respiratory Tract

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-04
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., encephalitis, retinitis, and death Nuclear and cytoplasmic inclusions Nuclear inclusions range from nonspecific smudged chromatin to “owl-eye” in appearance, i.e, basophilic with surrounding nuclear halo, chromatin compressed to the nuclear membrane Cytoplasmic inclusion material is granular and basophilic...
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Book Chapter

Cardiac Rhabdomyoma

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch43
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
...Table 43-1 DIAGNOSIS OF TUBEROUS SCLEROSIS COMPLEX a Major Diagnostic Features b  Cardiac rhabdomyoma  Hypomelanotic macules (≥3 in number, each ≥5 mm)  Angiofibromas (≥3)  Ungual fibromas (≥2)  Shagreen patch  Multiple retinal hamartomas...
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Book Chapter

Vasculitis

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch30
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... types. Giant cell arteritis most often involves branches of the aortic arch, extending to the ophthalmic and retinal arteries. However, any branch of the aorta can be involved, and isolated giant cell arteritis occurs in a variety of organ sites ( 30 – 32 ). Because the temporal artery...
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Book Chapter

Connective Tissue Disorders

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch31
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... myopia, as well as ectopia lentis, retinal detachment, and cataracts. From a cardiovascular standpoint, the disorder affects the aorta (dilatation), heart valves (mitral valve prolapse), and myocardium (cardiomyopathy). Microscopic Findings. Similar to the gross vascular findings in MFS, histopathologic...
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Book Chapter

Infective Endocarditis

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch12
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... ), splinter hemorrhages, Janeway lesions (nontender erythematous macules on the palms and soles), and retinal Roth spots (edematous hemorrhagic lesions with pale centers). IE is often dichotomized into community-associated and nosocomial types. A precise definition as to what constitutes the latter is lacking...
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Book Chapter

Atherosclerosis and Systemic Hypertension

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch29
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... include the heart, kidneys, and brain ( Table 29-1 ). Effects on the heart are discussed in chapter 20 . Hypertension also affects retinal vessels, in the form of hypertensive retinopathy ( 52 ). Hypertension is the most significant risk factor for stroke, both hemorrhagic and ischemic, but especially...
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Book Chapter

Other Types of Cardiomyopathy

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch19
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
.... Refsum disease is one of the prototypical peroxisomal diseases. It is an autosomal recessive condition characterized by anosmia and early-onset retinitis pigmentosa that occurs often in association with deafness, neuropathy, ataxia, and cardiomyopathy. Refsum disease is primarily caused by mutations...
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Book Chapter

Germ Cell Tumors

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-13
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
..., retinal tissue may have an immature or maturing appearance. This should not be classified as immature when the tissue is organized and organoid and mitoses and apoptosis are lacking. Treatment and Prognosis. High-grade immature teratomas are typically treated with chemotherapy. The prognosis...
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Images
Figure 4-169

TERATOMA, POSTPUBERTAL TYPE A: This tumor contains pigmented retinal-type ...

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in Germ Cell Neoplasia in Situ and Tumors Derived from Germ Cell Neoplasia in Situ > Tumors and Tumor-Like Lesions of the Testis and Adjacent Tissues
Published: 01 August 2022
TERATOMA, POSTPUBERTAL TYPE Figure 4-169 TERATOMA, POSTPUBERTAL TYPE A: This tumor contains pigmented retinal-type epithelium. B: Thyroid tissue is present. C: Prominent meningeal tissue with numerous psammoma bodies is seen. More about this image found in TERATOMA, POSTPUBERTAL TYPE A: This tumor contains pigmented retinal-type ...
Book Chapter

Miscellaneous Primary Testicular, Adnexal, and Spermatic Cord Tumors

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
10.55418/9781933477220-08
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... in the epithelioid cells are similar to those in the normal retinal epithelium and are easily identifiable in most cases; however, occasionally, the melanin pigment is not prominent, and Masson-Fontana stains aid in identification, which establishes the diagnosis ( 156 ). In cytologic preparations from hydrocele...
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Book Chapter

Germ Cell Neoplasia in Situ and Tumors Derived from Germ Cell Neoplasia in Situ

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
10.55418/9781933477220-04
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... and goblet cells. C: There are complex glands, some with a cribriform pattern. TERATOMA, POSTPUBERTAL TYPE Figure 4-169 TERATOMA, POSTPUBERTAL TYPE A: This tumor contains pigmented retinal-type epithelium. B: Thyroid tissue is present. C: Prominent meningeal tissue with numerous psammoma bodies is seen...
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Book Chapter

Tumors of the Neurosensory Retina and Retinal Pigment Epithelium

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 3
Published: 01 February 2021
10.55418/9781933477923-ch09
ISBN-10: 1-933477-92-X
ISBN: 978-1-933477-92-3
..., retinal detachment Exudate, retinal detachment, telangiectasias Eosinophils, histiocytes in partial retinal detachment, and vitreous at the base Retrolental membrane with funnel-shaped retinal detachment Calcifications Frequent Infrequent Infrequent Infrequent Other US a /MRI/CT...
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Images
Figure 5-8-1

FETUS PAPYRACEUS Retinal pigment and trunk with ribs are evident.

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in Placental Membranes > Atlas of Placental Pathology
Published: 01 August 2021
FETUS PAPYRACEUS Figure 5-8-1 FETUS PAPYRACEUS Retinal pigment and trunk with ribs are evident. More about this image found in FETUS PAPYRACEUS Retinal pigment and trunk with ribs are evident.