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Figure 1-26
Published: 01 December 2024
POSTNATAL REGRESSION OF PROVISIONAL ADRENAL CORTEX Figure 1-26 POSTNATAL REGRESSION OF PROVISIONAL ADRENAL CORTEX This 3-week postnatal adrenal gland shows necrosis and debris in the central part of the gland and a small amount of residual provisional cortex beneath the developing zona More about this image found in POSTNATAL REGRESSION OF PROVISIONAL ADRENAL CORTEX This 3-week postnatal a...
Images
Figure 1-27
Published: 01 December 2024
CYTOMEGALY IN REGRESSING FETAL CORTEX FROM A STILLBORN Figure 1-27 CYTOMEGALY IN REGRESSING FETAL CORTEX FROM A STILLBORN The nuclei are extremely large and occasional nuclear pseudoinclusions are formed by invagination of cytoplasm (arrow). More about this image found in CYTOMEGALY IN REGRESSING FETAL CORTEX FROM A STILLBORN The nuclei are extr...
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Figure 2-18
Published: 01 December 2024
BECKWITH-WIEDEMANN SYNDROME Figure 2-18 BECKWITH-WIEDEMANN SYNDROME A: Transverse sections of adrenal gland from a 3-week-old infant with Beckwith-Wiedemann syndrome are enlarged and show redundant cerebriform folds of cortex with demarcation between adult or definitive cortex and regressing More about this image found in BECKWITH-WIEDEMANN SYNDROME A: Transverse sections of adrenal gland from a...
Images
Figure 3-13
Published: 01 December 2024
dexamethasone. Skull X rays showed no abnormalities of the sella turcica. Following surgical removal of this 3-cm pheochromocytoma, hirsutism regressed and steroid levels normalized. Surgery was complicated by hypotensive episodes. The hyperplastic adrenal cortex was largely lipid depleted. Biopsy More about this image found in ECTOPIC ACTH SYNDROME DUE TO PHEOCHROMOCYTOMA A 51-year-old white female p...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-11
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... hydroxylase mRNA in blood and bone marrow. Stockholm: Karolinska Institute; 2009:27.) The incidence has remained stable over the past decades (with the exception of countries that introduced and subsequently abandoned national screening programs (see under Spontaneous Regression and Maturation) ( 7 – 19...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-01
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... of the latter include pseudorosettes (Homer Wright rosettes) ( fig. 1-10 ), which can also be found in the developing sympathetic chain (see fig. 1-9 ). With postnatal regression of the fetal cortex, the developing medullary cells aggregate to the area of the central vein. However, the adrenal medulla achieves...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-02
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... redundant cerebriform folds of cortex with demarcation between adult or definitive cortex and regressing and hemorrhagic regressing fetal or provisional cortex. B: Developing adult cortex at left of field, with fetal cortex at right. At this early stage in postnatal life, fetal cortex is undergoing normal...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-03
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... with hypertension, facial swelling, and hirsutism. There were elevated steroid metabolites in the urine which could not be suppressed with high-dose dexamethasone. Skull X rays showed no abnormalities of the sella turcica. Following surgical removal of this 3-cm pheochromocytoma, hirsutism regressed and steroid...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-04
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... of “adenoma-like” macronodules ( 39 ). Spontaneous regression of cortisol secretion has been reported. However, the treatment of choice for PPNAD is bilateral adrenalectomy ( 2 ). Pathologic Findings. The adrenal surface may be apparently normal, with nodules recognizable only on sectioning the gland...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-12
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... adrenal hematomas may undergo regression, sometimes with residual dystrophic calcification and possibly cyst formation ( 77 , 79 ). ADRENAL CYSTS The current classification of adrenal cysts continues to be based on a 1966 iteration of a schema dating to 1906 in which these lesions...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-06
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... of stepwise regression analysis. The score is based on the following: 3 points for a mitotic count over 5 per 50 high-power fields/10 mm2, plus 5 points for tumor necrosis if present, plus the numeric value of the Ki-67 proliferative index in the most proliferative area of the tumor. A Helsinki...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-09
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... with an increased regression of HSIL, reduced prevalence of ASIL, or reduced incidence of invasive anal cancer ( 45 , 48 ). The incidence of HPV-related oropharyngeal squamous cell carcinoma (OPSCC) has increased over the last two decades, especially in men ( 41 , 49 ). HPV attributable OPSCC is more...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-08
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
...) needs to be assessed in each patient. Frequently, changing the type of immunosuppressive medication can lead to regression of KS. HHV8 neoplasia that develops in patients without iatrogenic immunosuppression (children or the elderly) should be treated with an appropriate cytotoxic chemotherapeutic...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-06
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... be pedunculated Erythema around the lesion signals regression Bacterial superinfection Other skin infections, including verruca vulgaris, condyloma acuminatum, chickenpox, and bacterial folliculitis Skin tumors, including syringoma, basal cell carcinoma, and steatocystoma Other skin infections, including acne...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-13
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., especially lymphoid follicles, may take months to years to regress ( 86 ). Treatment with proton pump inhibitors (PPI) is typically associated with proximal migration of organisms and associated inflammation. Patients with H. pylori infection have up to a four-fold increased risk for duodenal...
Images
Figure 4-7
Published: 01 February 2024
COMPOUND DYSPLASTIC NEVUS WITH PARTIAL REGRESSION Figure 4-7 COMPOUND DYSPLASTIC NEVUS WITH PARTIAL REGRESSION There is a gap (arrows) in the dermal melanocyte population, with inflammation and slightly hypervascular stroma separating dermal nevus cell aggregates. More about this image found in COMPOUND DYSPLASTIC NEVUS WITH PARTIAL REGRESSION There is a gap (arrows) ...
Images
Figure 15-8
Published: 01 February 2024
NODULAR MELANOMA ASSOCIATED WITH FEATURES OF REGRESSION Figure 15-8 NODULAR MELANOMA ASSOCIATED WITH FEATURES OF REGRESSION An intradermal densely cellular nodule of melanoma is present. The adjacent dermis shows features suggesting regression (hypervascularity, fibrosis, lymphocytes More about this image found in NODULAR MELANOMA ASSOCIATED WITH FEATURES OF REGRESSION An intradermal den...
Images
Figure 6-10
Published: 01 February 2024
NEVUS CHANGING UNDER IMMUNOTHERAPY Figure 6-10 NEVUS CHANGING UNDER IMMUNOTHERAPY Compound melanocytic nevus with features of partial regression. More about this image found in NEVUS CHANGING UNDER IMMUNOTHERAPY Compound melanocytic nevus with feature...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-23
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... Superficial spreading type Desmoplasia b Absent TILs c Non-brisk Regression Absent Associated nevus Absent Solar elastosis Mild Margin status details: Invasive tumor to deep margin Margin clearance >3 mm In situ melanoma to nearest side margin Margin...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-06
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... Figure 6-10 NEVUS CHANGING UNDER IMMUNOTHERAPY Compound melanocytic nevus with features of partial regression. REFERENCES REFERENCES 1. Schoenfeld   RJ , Pinkus   H . The recurrence of nevi after incomplete removal . AMA Arch Derm   1958 ; 78 : 30 - 5 . 2. Cox   AJ , Walton...