Search Results for reactive

APICAL PERIODONTAL CYST Figure 5-128 APICAL PERIODONTAL CYST The cyst is lined by reactive squamous epithelium and the wall is highly inflamed. More about this image found in APICAL PERIODONTAL CYST The cyst is lined by reactive squamous epithelium ...

BENIGN ENLARGED CERVICAL LYMPH NODES Figure 7-12 BENIGN ENLARGED CERVICAL LYMPH NODES A–C: Reactive lymphoid hyperplasia shows a polymorphous population of lymphocytes, tingible body macrophages, and lymphohistiocytic aggregates. D: Non-necrotizing granulomatous inflammation can be associated More about this image found in BENIGN ENLARGED CERVICAL LYMPH NODES A–C: Reactive lymphoid hyperplasia sh...

MIDDLE EAR NEUROENDOCRINE TUMOR Figure 8-103 MIDDLE EAR NEUROENDOCRINE TUMOR The neoplastic cells are variably reactive with a number of different immunohistochemical markers: pancytokeratin shows most of the cells positive, although some are nonreactive (A); CK7 highlights the inner luminal More about this image found in MIDDLE EAR NEUROENDOCRINE TUMOR The neoplastic cells are variably reactive...

MIDDLE EAR NEUROENDOCRINE TUMOR Figure 8-104 MIDDLE EAR NEUROENDOCRINE TUMOR The neoplastic cells are variably reactive with a number of different peptides and transcription factors, including: nuclear INSM1 (A); membranous somatostatin receptor 2a (SSTR2a) (B); nuclear SATB2 (note slight More about this image found in MIDDLE EAR NEUROENDOCRINE TUMOR The neoplastic cells are variably reactive...

OSTEOSARCOMA Figure 5-192 OSTEOSARCOMA MDM2 reactivity in an osteosarcoma. More about this image found in OSTEOSARCOMA MDM2 reactivity in an osteosarcoma.

MENINGIOMA Figure 8-110 MENINGIOMA A: Cytoplasmic to membranous reactivity with EMA is noted in this meningioma. B: SSTR2A membranous reactivity in meningioma is helpful in confirming the diagnosis in selected cases. More about this image found in MENINGIOMA A: Cytoplasmic to membranous reactivity with EMA is noted in th...

MENINGIOMA Figure 1-162 MENINGIOMA A: The neoplastic cells show weak to strong, patchy cytoplasmic reactivity with epithelial membrane antigen (EMA). B: The native epithelium and minor mucoserous glands are reactive with CK7, while the meningioma is negative. More about this image found in MENINGIOMA A: The neoplastic cells show weak to strong, patchy cytoplasmic...

), diffuse cytoplasmic prolactin reactivity (E), and aberrant calcitonin reactivity (F). More about this image found in PitNET Immunohistochemistry findings that aid in the diagnosis of PitNET i...

MUCOSAL MELANOMA Figure 1-155 MUCOSAL MELANOMA No matter the pattern or the cytology, the neoplastic cells show variable reactivity with a number of melanocytic markers. A: Spindled cells with S-100 protein nuclear and cytoplasmic reactivity. B: Strong, diffuse, nuclear reaction with SOX10. C More about this image found in MUCOSAL MELANOMA No matter the pattern or the cytology, the neoplastic cel...

DESMOID-TYPE FIBROMATOSIS Figure 1-110 DESMOID-TYPE FIBROMATOSIS A,B: There is a strong nuclear β-catenin immunoreactivity, although not all cells are reactive. More about this image found in DESMOID-TYPE FIBROMATOSIS A,B: There is a strong nuclear β-catenin immunor...

ODONTOGENIC KERATOCYST Figure 5-152 ODONTOGENIC KERATOCYST The cyst on the left merges with significant inflammation below to produce reactive changes and the loss of diagnostic features of odontogenic keratocyst. More about this image found in ODONTOGENIC KERATOCYST The cyst on the left merges with significant inflam...

APICAL PERIODONTAL CYST Figure 5-129 APICAL PERIODONTAL CYST The cyst is lined by mature nonkeratinized stratified squamous epithelium without cytologic atypia but often with reactive epithelial hyperplasia. More about this image found in APICAL PERIODONTAL CYST The cyst is lined by mature nonkeratinized stratif...

BUCCAL BIFURCATION CYST Figure 5-137 BUCCAL BIFURCATION CYST Microscopic features are nonspecific, but are characterized by a reactive nonkeratinizing stratified squamous epithelial cyst lining with inflammation in its wall. More about this image found in BUCCAL BIFURCATION CYST Microscopic features are nonspecific, but are char...

PERINEURIOMA Figure 1-163 PERINEURIOMA A: This tumor is an entity in the differential diagnosis of meningioma, showing bland cells with elongated wavy nuclei. B,C: The lesional cells are reactive with claudin-1 (B) and GLUT1 (C), findings not seen in meningioma. More about this image found in PERINEURIOMA A: This tumor is an entity in the differential diagnosis of m...

SOLITARY FIBROUS TUMOR Figure 1-95 SOLITARY FIBROUS TUMOR A: Strong, diffuse, nuclear STAT6 immunohistochemistry confirms the diagnosis. B: Strong cytoplasmic membranous reactivity with CD34 is seen in most cases. Endothelial cells are used as internal control. More about this image found in SOLITARY FIBROUS TUMOR A: Strong, diffuse, nuclear STAT6 immunohistochemis...

INFANTILE HEMANGIOMA Figure 4-43 INFANTILE HEMANGIOMA A: In the proliferative phase, cellular lobules form dense masses. B,C: In the involution phase, dilated lumens become prominent. D: The endothelial cells in infantile hemangioma are reactive for GLUT1 immunohistochemistry. More about this image found in INFANTILE HEMANGIOMA A: In the proliferative phase, cellular lobules form ...

MODERATELY DIFFERENTIATED SQUAMOUS CELL CARCINOMA Figure 6-45 MODERATELY DIFFERENTIATED SQUAMOUS CELL CARCINOMA This moderately differentiated keratinizing-type SCC shows abundant, lightly basophilic (or myxoid) “desmoplastic” stroma which is reactive to the invading tumor nests. More about this image found in MODERATELY DIFFERENTIATED SQUAMOUS CELL CARCINOMA This moderately differen...

NEUROFIBROMA Figure 1-89 NEUROFIBROMA A,B: Some of the neoplastic cells are strongly S-100 protein reactive (A), with a similar population reacting with SOX10 (B). C: CD34 highlights numerous fibroblasts in this neurofibroma. D: Calretinin only highlights rare, isolated neurofibroma cells. More about this image found in NEUROFIBROMA A,B: Some of the neoplastic cells are strongly S-100 protein ...

NASOPHARYNGEAL CARCINOMA Figure 3-13 NASOPHARYNGEAL CARCINOMA A: Ancillary in situ hybridization is positive for EBER. B–D: There is diffuse immunohistochemical reactivity for CK5/6 (B), p40 (C), and p63 (D). E: Nasopharyngeal carcinomas often demonstrate positive membranous immunoreactivity More about this image found in NASOPHARYNGEAL CARCINOMA A: Ancillary in situ hybridization is positive fo...

LEIOMYOMA Figure 1-64 LEIOMYOMA A: Fat is part of this lipidized leiomyoma. B: Strong and diffuse reactivity for cytoplasmic smooth muscle actin. C: Desmin strongly highlights the cytoplasm of the neoplastic smooth muscle cells. D: CD31 reacts with the endothelial cells More about this image found in LEIOMYOMA A: Fat is part of this lipidized leiomyoma. B: Strong and diffu...