DUCTAL ADENOCARCINOMA Figure 7-7 DUCTAL ADENOCARCINOMA Intense desmoplastic reaction to the invasive carcinoma. The neoplastic glands have a haphazard distribution. More about this image found in DUCTAL ADENOCARCINOMA Intense desmoplastic reaction to the invasive carcin...

MIXED ACINAR-NEUROENDOCRINE CARCINOMA Figure 9-40 MIXED ACINAR-NEUROENDOCRINE CARCINOMA Immunolabeling for trypsin (A) and chromogranin (B) identifies the two components in the case from figure 9-39 . By double immunolabeling (C), the central acinar cells (blue reaction product) are sharply dist... More about this image found in MIXED ACINAR-NEUROENDOCRINE CARCINOMA Immunolabeling for trypsin (A) and c...

MIXED ACINAR-NEUROENDOCRINE CARCINOMA Figure 9-44 MIXED ACINAR-NEUROENDOCRINE CARCINOMA Double immunohistochemical labeling for trypsin (blue reaction product) and synaptophysin (brown reaction product) shows the relationship of the two cells types, which vary in amount regionally (A,B) and are i... More about this image found in MIXED ACINAR-NEUROENDOCRINE CARCINOMA Double immunohistochemical labeling ...

ARIAS STELLA REACTION Figure 3-85 ARIAS STELLA REACTION This phenomenon features glands with mucinous cytoplasm and markedly enlarged nuclei, many of which protrude toward the luminal space. (Courtesy of Dr. C. Otis, Springfield, MA) More about this image found in ARIAS STELLA REACTION This phenomenon features glands with mucinous cytopl...

SOLID PSEUDOPAPILLARY NEOPLASM Figure 11-15 SOLID PSEUDOPAPILLARY NEOPLASM A: The interface with the adjacent pancreas is often infiltrative, but there is no stromal reaction to the neoplasm. B: Islands of tumor are surrounded by pancreatic parenchyma, where the neoplastic cells resemble islets.... More about this image found in SOLID PSEUDOPAPILLARY NEOPLASM A: The interface with the adjacent pancreas...

INTRADUCTAL TUBULOPAPILLARY NEOPLASM WITH ASSOCIATED INVASIVE CARCINOMA Figure 6-59 INTRADUCTAL TUBULOPAPILLARY NEOPLASM WITH ASSOCIATED INVASIVE CARCINOMA Left: Irregular and angulated glands infiltrate the periductal stroma, with associated stromal reaction (inset). Right: Subtle nests and str... More about this image found in INTRADUCTAL TUBULOPAPILLARY NEOPLASM WITH ASSOCIATED INVASIVE CARCINOMA Le...

MIXED ACINAR-DUCTAL CARCINOMA Figure 9-47 MIXED ACINAR-DUCTAL CARCINOMA A: The mucinous acinar cell carcinoma pattern has a solid appearance, with regions closely resembling acinar cell carcinoma, but the periphery of the neoplasm has intracellular mucin. B: There is expression of trypsin (brown... More about this image found in MIXED ACINAR-DUCTAL CARCINOMA A: The mucinous acinar cell carcinoma patter...

TUBO-ENDOMETRIOID METAPLASIA Figure 3-86 TUBO-ENDOMETRIOID METAPLASIA Left: Simple, round to tubular glands are seen in the endocervical mucosa; the stroma can appear reactive and simulate desmoplastic reaction (upper right aspect). Right: The glands are lined by columnar epithelium with endomet... More about this image found in TUBO-ENDOMETRIOID METAPLASIA Left: Simple, round to tubular glands are see...

VULVAR SQUAMOUS CELL CARCINOMA, HPV INDEPENDENT, WITH CONSPICUOUS INTERFACE ATYPIA Figure 5-32 VULVAR SQUAMOUS CELL CARCINOMA, HPV INDEPENDENT, WITH CONSPICUOUS INTERFACE ATYPIA Although not pathognomonic, keratinizing tumors with irregularly shaped, frankly infiltrative nests eliciting a fibromyxoid stromal reaction (left) and interface atypia at high power (right) are typically independent from HPV infection and harbor TP53 abnormalities. More about this image found in VULVAR SQUAMOUS CELL CARCINOMA, HPV INDEPENDENT, WITH CONSPICUOUS INTERFACE...

ENDOMETRIAL CARCINOMA INVOLVING THE CERVIX Figure 3-74 ENDOMETRIAL CARCINOMA INVOLVING THE CERVIX Secondary spread to the cervix from an endometrial tumor can be seen as direct spread (A) or as a skip lesion, discontinuous with the dominant mass. This endometrial endometrioid carcinoma shows conv... More about this image found in ENDOMETRIAL CARCINOMA INVOLVING THE CERVIX Secondary spread to the cervix ...