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pulmonary
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Images
Published: 01 December 2024
PULMONARY PARAGANGLIOMA Figure 9-32 PULMONARY PARAGANGLIOMA A: This paraganglioma was a solitary lesion initially interpreted as an epithelial pulmonary NET. The patient was found to have a hereditary SDHC mutation. No other primary tumors were found and this tumor contained abundant sustentacular cells. In view of the clinical and histologic findings and the low metastasis frequency associated with SDHC mutation, the tumor was consistent with a primary pulmonary paraganglioma. B: High magnification shows nested architecture and cells of varied sizes. C: S-100 protein highlights sustentacular cells. More about this image found in PULMONARY PARAGANGLIOMA A: This paraganglioma was a solitary lesion initia...
Images
Published: 01 December 2024
ADRENAL CORTICAL CARCINOMA Figure 6-8 ADRENAL CORTICAL CARCINOMA An ACC from a 32-year-old female weighed 2,200 g and measured 21 cm in diameter. There were extensive areas of necrosis with foci of vascular invasion. The patient also had pulmonary metastases at the time of diagnosis. More about this image found in ADRENAL CORTICAL CARCINOMA An ACC from a 32-year-old female weighed 2,200 ...
Images
Published: 01 December 2024
PRIMARY PIGMENTED NODULAR ADRENOCORTICAL DISEASE Figure 4-24 PRIMARY PIGMENTED NODULAR ADRENOCORTICAL DISEASE A large pigmented macronodule and a larger pale yellow nodule with small areas of necrosis are seen. The patient was part of a family pedigree with the complex of myxomas, spotty pigmenta... More about this image found in PRIMARY PIGMENTED NODULAR ADRENOCORTICAL DISEASE A large pigmented macrono...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-03
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... source should include the neck (to detect potential medullary thyroid carcinoma), the thorax (for thymic or pulmonary neuroendocrine tumors), the abdomen (where pancreatic neuroendocrine tumors are the most common source of ectopic ACTH), and the pelvis. The use of Ga68-dotate positron emission...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-09
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... malignant mimics include sparse mitoses and absence of cell polarity. CARDIAC PARAGANGLIOMA Figure 9-31 CARDIAC PARAGANGLIOMA This primary cardiac paraganglioma infiltrates myocardium at lower right. PULMONARY PARAGANGLIOMA Figure 9-32 PULMONARY PARAGANGLIOMA A: This paraganglioma was a solitary...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-10
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... the degree of cellular maturity or differentiation because normal paraganglia are fully mature organs that may produce dopamine ( 9 ) or norepinephrine ( 10 ). The nonhereditary syndromes frequently involve somatic mosaicism and include Carney triad (paraganglioma, pulmonary chondroma, and SDH-deficient...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-12
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... in cases where a combination of unilateral adrenal enlargement and multiple pulmonary nodules suggests pulmonary metastases from a primary adrenal tumor. Adrenal involvement by SMARCA4-deficient thoracic tumors may be a potential pitfall in the differential diagnosis with adrenal cortical carcinoma due...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-04
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... cortical nodular diseases is covered in chapter 7 . Adrenal cortical proliferations, usually without clinical or biochemical evidence of hormone hypersecretion, have been described in the context of Carney triad ( 3 ). This is the combination of gastric gastrointestinal stromal tumor (GIST), pulmonary...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-07
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... syndrome FLCN Oncocytic adenoma (in case reports) <1% Skin hamartomas, pulmonary cysts, oncocytoid renal neoplasms (oncocytoma and renal cell carcinoma) Li-Fraumeni syndrome TP53 Carcinoma 3-5% (adults) 50-80% (children) Gliomas, breast and lung carcinomas, sarcomas...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-06
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... pulmonary metastases at the time of diagnosis. ADRENAL CORTICAL CARCINOMA Figure 6-9 ADRENAL CORTICAL CARCINOMA This large ACC was resected from a 27-year-old woman with virilization. The tumor measured 17 cm in diameter and invaded both kidney and spleen, which necessitated en bloc removal...
Images
Published: 01 September 2024
PULMONARY COVID-19 Figure 4-10 PULMONARY COVID-19 A: Initial changes show some intra-alveolar fibrin with focal early hyaline membrane formation, scattered intra-alveolar red blood cells, and focal mild interstitial lymphocyte infiltration. B: Low-power view of patchy intra-alveolar fibrin with ... More about this image found in PULMONARY COVID-19 A: Initial changes show some intra-alveolar fibrin with...
Images
Published: 01 September 2024
SEVERE FLAVIVIRUS INFECTION Figure 5-14 SEVERE FLAVIVIRUS INFECTION A: Early pulmonary edema in dengue. B: Striking intra-alveolar hemorrhage in yellow fever. (Courtesy of the CDC IDPB) More about this image found in SEVERE FLAVIVIRUS INFECTION A: Early pulmonary edema in dengue. B: Striki...
Images
Published: 01 September 2024
PULMONARY TUBERCULOSIS Figure 12-50 PULMONARY TUBERCULOSIS Prominent consolidation (A,B), multiple circumscribed small tubercles (C), extensive parenchymal destruction with cavitation (B), and focal secondary bronchiectasis are seen. More about this image found in PULMONARY TUBERCULOSIS Prominent consolidation (A,B), multiple circumscrib...
Images
Published: 01 September 2024
PULMONARY TUBERCULOSIS Figure 12-55 PULMONARY TUBERCULOSIS Striking fibrillogranular (caseous) necrosis has been extruded into a bronchiole demonstrating extensive squamous metaplasia (top right). More about this image found in PULMONARY TUBERCULOSIS Striking fibrillogranular (caseous) necrosis has be...
Images
Published: 01 September 2024
PULMONARY TUBERCULOSIS Figure 12-58 PULMONARY TUBERCULOSIS Anergic granuloma formation (A) with a paucity of inflammatory cells and associated high organism burden on an acid-fast stain (B). More about this image found in PULMONARY TUBERCULOSIS Anergic granuloma formation (A) with a paucity of i...
Images
Published: 01 September 2024
PULMONARY INFECTION DUE TO MYCOBACTERIUM KANSASII Figure 15-32 PULMONARY INFECTION DUE TO MYCOBACTERIUM KANSASII Macroscopy (A) and microscopy (B,C) of a lung abscess, and with an acid-fast stain (D). More about this image found in PULMONARY INFECTION DUE TO MYCOBACTERIUM KANSASII Macrosc...
Images
Published: 01 September 2024
PULMONARY COCCIDIOIDOMYCOSIS Figure 21-8 PULMONARY COCCIDIOIDOMYCOSIS Confluent well-formed granulomatous foci have prominent foreign body-type multinucleated giant cells (A), and prominent necrosis with secondary cavitation (B). (Courtesy of the CDC PHIL) More about this image found in PULMONARY COCCIDIOIDOMYCOSIS Confluent well-formed granulomatous foci have...
Images
Published: 01 September 2024
INVASIVE PULMONARY ASPERGILLOSIS Figure 21-29 INVASIVE PULMONARY ASPERGILLOSIS Ulcerative bronchitis and extensive associated necrosis (A) with abundant fungal hyphae (B). More about this image found in INVASIVE PULMONARY ASPERGILLOSIS Ulcerative bronchitis and extensive assoc...
Images
Published: 01 September 2024
PULMONARY HISTOPLASMOSIS Figure 23-4 PULMONARY HISTOPLASMOSIS Zonal granuloma formation (A) with multiple histiocytes containing a large number of intracytoplasmic Histoplasma spp yeasts (B) are highlighted by a Grocott methenamine stain (GMS) (C). More about this image found in PULMONARY HISTOPLASMOSIS Zonal granuloma formation (A) with multiple histi...
Images
Published: 01 September 2024
HANTAVIRUS CARDIOPULMONARY SYNDROME (HCPS) Figure 4-19 HANTAVIRUS CARDIOPULMONARY SYNDROME (HCPS) Typical chest X-ray features of severe pulmonary edema. (Courtesy of the CDC PHIL) More about this image found in HANTAVIRUS CARDIOPULMONARY SYNDROME (HCPS) Typical chest X-ray features of...
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