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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-05
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... and focally, thus not posing differential diagnostic problems. The diffuse growth typical of adrenal carcinoma is usually not seen, although it may be present in the oncocytic variant. CORTISOL-SECRETING ADRENAL CORTICAL ADENOMA Figure 5-19 CORTISOL-SECRETING ADRENAL CORTICAL ADENOMA A: This adenoma...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-12
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... angiosarcoma usually presents little difficulty in diagnosis when there is a clear vasoformative pattern ( fig. 12-10A ). Problems arise with tumors having a solid pattern composed of epithelioid or spindle cells (seen focally in fig. 12-10B and to a greater extent in fig. 12-10C ). For these tumors...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-04
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... on studies of nonfunctioning lesions larger than 1 cm, thus simulating an adrenal cortical adenoma. Currently, this disorder is usually detected as an incidental finding on high-resolution CT scan, magnetic resonance imaging (MRI), or during ultrasound examination for an unrelated problem or during...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-09
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
...   A , Parkinson   C . Paraganglial cells of urinary bladder and prostate: potential diagnostic problem . J Clin Pathol   1990 ; 43 : 13 - 6 . 14. Guild   SR . The glomus jugulare, a nonchromaffin paraganglion, in man . Ann Otol Rhinol Laryngol   1953 ; 62 : 1045 - 71 . 15. Kjaergaard   J...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-29
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... . Semin Diagn Pathol   2019 ; 36 : 164 - 9 . 2. Freitas-Lidani   KC , Antunes-Andrade   F , Bavia   L , et al . Chagas disease: from discovery to a worldwide health problem . Front Public Health   2019 ; 7 : 166 . 3. American trypanosomiasis . Centers for Disease Control...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-26
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., as well as serology. Direct microscopy of stool or rectal swab material is still the most commonly used diagnostic test, although this method remains notoriously insensitive ( fig. 26-14 ). Specificity is also a problem, as this technique cannot reliably distinguish between E. histolytica...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-13
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
...OVERVIEW Acute Bacterial Gastrointestinal Infections Diarrheal disease due to gastrointestinal tract (GIT) infections is a major global health problem and remains one of the leading causes of child morbidity and mortality worldwide ( 1 ). Although a specific pathogen cannot be identified...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-05
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
...VIRAL HEPATITIS General Considerations, Including Etiology and Synonyms Viral hepatitis is a major worldwide health problem that is most frequently caused by the five hepatotropic viruses: hepatitis A (HAV), B (HBV), C (HCV...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-03
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., or meningoencephalitis Neurologic or neuropsychiatric sequelae Fatality rate: 1-2% (higher in severe disease) POWV Not known 8-34 days Febrile polio-like illness Aseptic meningitis, encephalitis, or meningoencephalitis Ophthalmoplegia Memory problems, hemiplegia in 50% of survivors Fatality rate: 10%. ZIKA...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-25
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
.... If the patient has anti-Toxoplasma IgG antibodies, the tachyzoite staining is inhibited by the antibodies, which bind the added complement. Other serologic techniques include indirect immunofluorescence, agglutination, and enzyme immunoassays ( 2 ). Problems with the interpretation of serologic results...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-04
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... and rhabdomyolysis, and cardiac manifestations such as myocarditis, pericarditis, and exacerbations of underlying cardiac problems. There may be central nervous system (CNS) complications, including transverse myelitis, Guillain-Barre syndrome, encephalitis, encephalomyelitis, and aseptic meningitis. In children...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-12
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... resistant to different antibiotics has created a major problem worldwide when treating infections by this organism. Epidemiology S. aureus colonizes the skin and upper respiratory tract of approximately 30 percent of individuals ( 22 ). Pneumonia can result from aspiration of these colonizing...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-14
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... . Advancement of knowledge of Brucella over the past 50 years . Vet Pathol   2014 ; 51 : 1076 - 89 . 2. Facciolà   A , Palamara   MA , D’Andrea   G , et al . Brucellosis is a public health problem in southern Italy: burden and epidemiological trend of human and animal disease . J Infect...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-09
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., as the cause. This syndrome may turn out to be a consequence of chronic LIP. Gastrointestinal Disease in HIV Infection. Since the start of the HIV pandemic, clinical gastrointestinal problems have dominated patient management. A major feature of untreated HIV in the pre-HAART era was the fatal wasting...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-13
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... melanoma is not. Inflamed Scar versus LMM with Desmoplastic Invasive Tumor. Another diagnostic problem is the distinction of an inflamed scar in the excision of a LM from desmoplastic melanoma associated with a LM. This problem is discussed further in chapter 16 . Intrafollicular Melanoma in Situ versus...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-20
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... of the presence of pagetoid spread. Combined nevi, such as BAP1-deficient melanocytomas, deep penetrating nevi, or cellular blue nevi with mitoses may also be problematic, and the distinction of atypical Spitz nevi/tumors from melanoma is notoriously challenging. For many diagnostic problems, but in particular...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-21
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... microscopic variants melanoma, including, but not limited, to verrucous ( 17 ), polypoid, nested, neurotropic, and signet ring cell melanomas. Verrucous melanoma is mainly a problem for clinicians who may mistake it for a wart or seborrheic keratosis. Histopathologically, it is usually not difficult...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-15
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
.... This definition addresses two important issues: the clinical problem of early detection and the potential confusion with metastatic melanoma. Nodular Melanoma versus Melanocytic Nevi, Proliferative Nodules, or Melanocytomas. Nodular melanoma also needs to be distinguished from various benign melanocytic tumors...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-23
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... acknowledging such problems. If the practice setting includes a group of dermatopathologists, sharing challenging cases with colleagues is prudent practice. One may also consult with experts for their opinions and utilize ancillary studies. Documentation of such review and the use of ancillary studies...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-22
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... nonmelanocytic neoplasms. Depending on the diagnostic problem (e.g., metastatic melanoma versus poorly differentiated carcinoma, lymphoma, or sarcoma) a set of antibodies to melanocytic differentiation antigens, as well as epithelial, lymphoid, and mesenchymal markers, may be necessary for a precise diagnosis...