IMMUNOHISTOCHEMICAL POSITIVE CONTROL FOR STAPHYLOCOCCUS AUREUS Figure 1-3 IMMUNOHISTOCHEMICAL POSITIVE CONTROL FOR STAPHYLOCOCCUS AUREUS The positive (dark red) bacteria are formalin-fixed and paraffin-embedded between sectioned fragments of normal tissue. (Courtesy of the Centers for Disease Control and Prevention [CDC] Infectious Disease Pathology Branch (IDPB) More about this image found in IMMUNOHISTOCHEMICAL POSITIVE CONTROL FOR STAPHYLOCOCCUS AUREUS...

IMMUNOHISTOCHEMISTRY IN VARIANT CREUTZFELD-JAKOB DISEASE Figure 2-7 IMMUNOHISTOCHEMISTRY IN VARIANT CREUTZFELD-JAKOB DISEASE A: Positive amyloid plaque on immunohistochemical staining. (Courtesy of the Armed Forces Institute of Pathology) B: Synaptic pattern of PrP^SC immunohistochemical staining. More about this image found in IMMUNOHISTOCHEMISTRY IN VARIANT CREUTZFELD-JAKOB DISEASE A: Positive amylo...

RESPIRATORY SYNCYTIAL VIRUS Figure 4-25 RESPIRATORY SYNCYTIAL VIRUS Positive indirect fluorescent assay for RSV. (Courtesy of the CDC PHIL) More about this image found in RESPIRATORY SYNCYTIAL VIRUS Positive indirect fluorescent assay for RSV. (...

CHLAMYDIA PSITTACI Figure 12-37 CHLAMYDIA PSITTACI Positive immunofluorescence assay. (Courtesy of the CDC PHIL) More about this image found in CHLAMYDIA PSITTACI Positive immunofluorescence assay. (Co...

POSITIVE FITE-FARACO STAIN Figure 15-24 POSITIVE FITE-FARACO STAIN Nasal discharge smear. More about this image found in POSITIVE FITE-FARACO STAIN Nasal discharge smear.

ACTINOMYCETOMA Figure 24-18 ACTINOMYCETOMA Gram stain highlights the filamentous gram-positive bacteria in this granule. (Courtesy of Dr T. Pitjadi, Ampath Pathology Laboratories, Johannesburg, South Africa) More about this image found in ACTINOMYCETOMA Gram stain highlights the filamentous gram-positive bacteri...

FLA INFECTION Figure 25-19 FLA INFECTION Positive immunofluorescence (A, Naegleria) and immunohistochemistry (B, Balamuthia) staining confirm the diagnosis. (Courtesy of the CDC PHIL and CDC IDPB) More about this image found in FLA INFECTION Positive immunofluorescence (A, Naegleria) ...

INFLUENZA VIRUS IMMUNOHISTOCHEMISTRY Figure 4-4 INFLUENZA VIRUS IMMUNOHISTOCHEMISTRY The positivity in the superficial bronchial (A) and underlying glandular (B) epithelia confirms the presence of influenza virus. More about this image found in INFLUENZA VIRUS IMMUNOHISTOCHEMISTRY The positivity in the superficial bro...

HANTAVIRUS INFECTION Figure 4-22 HANTAVIRUS INFECTION Positivity for hantavirus in the endothelium of the lung (A) and kidney (glomerulus, B). (Courtesy of the CDC IDPB) More about this image found in HANTAVIRUS INFECTION Positivity for hantavirus in the endothelium of the l...

HBV C-ANTIGEN Figure 5-7 HBV C-ANTIGEN There is strong diffuse nuclear positivity in hepatocytes with “sanded” nuclei. More about this image found in HBV C-ANTIGEN There is strong diffuse nuclear positivity in hepatocytes wi...

NASOPHARYNGEAL CARCINOMA Figure 8-12 NASOPHARYNGEAL CARCINOMA Strong epithelial positivity is seen on EBV-encoded small RNA (EBER) in situ hybridization (ISH), confirming the EBV association of the tumor. More about this image found in NASOPHARYNGEAL CARCINOMA Strong epithelial positivity is seen on EBV-encod...

KAPOSI SARCOMA Figure 8-20 KAPOSI SARCOMA Strong diffuse endothelial marker positivity, including CD34 (illustrated), is typical of Kaposi sarcoma. More about this image found in KAPOSI SARCOMA Strong diffuse endothelial marker positivity, including CD3...

EBOLA VIRUS IMMUNOHISTOCHEMISTRY Figure 10-4 EBOLA VIRUS IMMUNOHISTOCHEMISTRY A skin biopsy shows strong red positivity (A,B) and filamentous viral particles illustrated on transmission electron microscopy (C). (Courtesy of the CDC IDPB and the CDC PHIL) More about this image found in EBOLA VIRUS IMMUNOHISTOCHEMISTRY A skin biopsy shows strong red positivity...

IMMUNOHISTOCHEMICAL ASSAY FOR LASSA VIRUS Figure 10-9 IMMUNOHISTOCHEMICAL ASSAY FOR LASSA VIRUS Positivity in the lung (A) and liver (B). (Courtesy of the CDC IDPB) More about this image found in IMMUNOHISTOCHEMICAL ASSAY FOR LASSA VIRUS Positivity in the lung (A) and l...

WHIPPLE DISEASE Figure 13-39 WHIPPLE DISEASE There is strong diastase-resistant PAS positivity in the macrophage infiltrate (A; alcian blue/PAS-d stain). Specific T. whipplei immunohistochemical testing is also available (B,C). (Courtesy of Dr. E. Montgomery, University of Miami, Miami, FL) More about this image found in WHIPPLE DISEASE There is strong diastase-resistant PAS positivity in the m...

SEVERE MALARIA Figure 27-4 SEVERE MALARIA A–D: Granular red erythrocyte positivity on immunohistochemical staining in patients with severe malaria. (Courtesy of the CDC IDPB) More about this image found in SEVERE MALARIA A–D: Granular red erythrocyte positivity on immunohistochem...

HSIL/LSIL Figure 9-40 HSIL/LSIL A: HSIL with diffuse, strong cytoplasmic and nuclear (“block”) staining for p16, interpreted as a positive result. B: LSIL on the right (short arrow), while the differential diagnosis for the area on the left (long arrow) includes immature squamous metaplasia and ... More about this image found in HSIL/LSIL A: HSIL with diffuse, strong cytoplasmic and nuclear (“block”) s...

GRAM STAIN OF SKIN AND SOFT TISSUE INFECTIONS BY VARIOUS BACTERIA Figure 15-4 GRAM STAIN OF SKIN AND SOFT TISSUE INFECTIONS BY VARIOUS BACTERIA Clostridium spp (gram positive bacilli; A), Streptococcus spp (gram-positive cocci; B), Acinetobacter spp (gram-negative coccobacilli; C) and Klebsiella spp (gram-negative bacilli; D). More about this image found in GRAM STAIN OF SKIN AND SOFT TISSUE INFECTIONS BY VARIOUS BACTERIA ...

MERKEL CELL CARCINOMA Figure 9-50 MERKEL CELL CARCINOMA A: At low power, the small round blue cell tumor is centered on the dermis. B: Higher power shows sheets of cells with a high nuclear to cytoplasmic ratio, prominent apoptosis, and brisk mitotic activity. C: Classic paranuclear “dot-like” ... More about this image found in MERKEL CELL CARCINOMA A: At low power, the small round blue cell tumor is ...

ACTINOMYCOSIS Figure 12-31 ACTINOMYCOSIS High-power microscopic view of scattered filamentous, gram-positive Actinomyces bacilli. (Courtesy of the CDC PHIL) More about this image found in ACTINOMYCOSIS High-power microscopic view of scattered filamentous, gram-p...