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STROMAL REACTION TO RUPTURED CYST  A: A core needle biopsy specimen shows f...
Published: 01 January 2024
STROMAL REACTION TO RUPTURED CYST Figure 2-21 STROMAL REACTION TO RUPTURED CYST A: A core needle biopsy specimen shows fibroadipose tissue with a chronic inflammatory cell infiltrate and stromal fibrosis. B: High-power view demonstrates histiocytes, lymphocytes, and plasma cells; while not defin... More about this image found in STROMAL REACTION TO RUPTURED CYST A: A core needle biopsy specimen shows f...
Images
ROSAI-DORFMAN DISEASE  A: A low-power view of a core needle biopsy shows fi...
Published: 01 January 2024
ROSAI-DORFMAN DISEASE Figure 2-4 ROSAI-DORFMAN DISEASE A: A low-power view of a core needle biopsy shows fibrous breast parenchyma with a mixed chronic inflammatory cell infiltrate. B: Higher power reveals the presence of histiocytes, lymphocytes, and plasma cells. C: High power shows a histioc... More about this image found in ROSAI-DORFMAN DISEASE A: A low-power view of a core needle biopsy shows fi...
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INVASIVE CARCINOMA WITH MEDULLARY-LIKE PATTERN  A: This tumor is composed o...
Published: 01 January 2024
INVASIVE CARCINOMA WITH MEDULLARY-LIKE PATTERN Figure 8-20 INVASIVE CARCINOMA WITH MEDULLARY-LIKE PATTERN A: This tumor is composed of solid sheets of cells with large, pleomorphic nuclei. B: At high power, abundant admixed lymphocytes and plasma cells are appreciated (tumor-infiltrating lymphoc... More about this image found in INVASIVE CARCINOMA WITH MEDULLARY-LIKE PATTERN A: This tumor is composed o...
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MAMMARY DUCT ECTASIA: EARLY STAGE  A: Low-power view demonstrates dilated d...
Published: 01 January 2024
MAMMARY DUCT ECTASIA: EARLY STAGE Figure 2-1 MAMMARY DUCT ECTASIA: EARLY STAGE A: Low-power view demonstrates dilated ducts with a surrounding chronic inflammatory cell infiltrate and luminal secretion. Histiocytes are apparent in the epithelial lining and duct lumen. B: Intermediate power shows... More about this image found in MAMMARY DUCT ECTASIA: EARLY STAGE A: Low-power view demonstrates dilated d...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-03
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
..., similar to plasma cells. Oncocytic change refers to swollen eosinophilic granular cytoplasm. When melanocytes have abundant clear cytoplasm, this phenotype is typically referred to as balloon cell change ( fig. 3-16 ). MELANOCYTIC NEVUS WITH FATTY METAPLASIA Figure 3-11 MELANOCYTIC NEVUS WITH FATTY...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-02
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... Findings. Microscopic evaluation reveals dilated ducts with associated periductal inflammation composed of histiocytes, lymphocytes, and plasma cells. The epithelial lining of the ducts is usually attenuated. Histiocytes infiltrate the duct wall and epithelial lining, and are also present within the duct...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-01
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
...), terminal duct, and lobules, in turn composed of acini, is seen. The TDLU is embedded within a myxoid-appearing, hormone-responsive, fibrovascular stroma that has varying numbers of lymphocytes, plasma cells, macrophages, and mast cells. This specialized intralobular stroma is distinct from the surrounding...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-11
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... molecular alterations associated with PASH. INFLAMMATORY MYOFIBROBLASTIC TUMOR Definition.  Inflammatory myofibroblastic tumor is a fibroblastic/myofibroblastic tumor with a prominent lymphocytic and plasma cell infiltrate. Its occurrence in the breast is rare. Clinical Features. Inflammatory...
Images
SCLEROSING PERIAORTITIS/IGG4-RELATED AORTITIS  IgG4 immunohistochemical stu...
Published: 15 November 2023
SCLEROSING PERIAORTITIS/IGG4-RELATED AORTITIS Figure 30-20 SCLEROSING PERIAORTITIS/IGG4-RELATED AORTITIS IgG4 immunohistochemical study shows increased IgG4-reactive plasma cells. More about this image found in SCLEROSING PERIAORTITIS/IGG4-RELATED AORTITIS IgG4 immunohistochemical stu...
Images
CARDIAC ROSAI-DORFMAN DISEASE  This histiocytic proliferation characteristi...
Published: 15 November 2023
CARDIAC ROSAI-DORFMAN DISEASE Figure 57-15 CARDIAC ROSAI-DORFMAN DISEASE This histiocytic proliferation characteristically has a brisk inflammatory backdrop consisting of lymphocytes and plasma cells. More about this image found in CARDIAC ROSAI-DORFMAN DISEASE This histiocytic proliferation characteristi...
Images
IGG4-RELATED PERICARDITIS  Left: Chronic fibrosing pericarditis with a bris...
Published: 15 November 2023
IGG4-RELATED PERICARDITIS Figure 27-14 IGG4-RELATED PERICARDITIS Left: Chronic fibrosing pericarditis with a brisk lymphoplasmacytic infiltrate in the background of dense fibrosis. Right: There are numerous IgG4-reactive plasma cells. More about this image found in IGG4-RELATED PERICARDITIS Left: Chronic fibrosing pericarditis with a bris...
Images
LYMPHOPLASMACYTIC AORTITIS  There may be areas of macrophages and occasiona...
Published: 15 November 2023
LYMPHOPLASMACYTIC AORTITIS Figure 30-17 LYMPHOPLASMACYTIC AORTITIS There may be areas of macrophages and occasional giant cells, in addition to lymphocytes and plasma cells, but necrotizing granulomas are absent, and the elastic layers are largely intact, as shown with this elastic stain. More about this image found in LYMPHOPLASMACYTIC AORTITIS There may be areas of macrophages and occasiona...
Images
ACUTE RHEUMATIC FEVER  Left: An Aschoff nodule within the myocardium consis...
Published: 15 November 2023
ACUTE RHEUMATIC FEVER Figure 21-1 ACUTE RHEUMATIC FEVER Left: An Aschoff nodule within the myocardium consists of T lymphocytes, plasma cells, and activated macrophages. Right: The activated macrophages within the Aschoff nodule are called Anitschkow cells and can have the appearance of owl’s ey... More about this image found in ACUTE RHEUMATIC FEVER Left: An Aschoff nodule within the myocardium consis...
Images
POST-TRANSPLANT LYMPHOPROLIFERATIVE DISORDER (PTLD)  A: Two discrete gross ...
Published: 15 November 2023
POST-TRANSPLANT LYMPHOPROLIFERATIVE DISORDER (PTLD) Figure 24-17 POST-TRANSPLANT LYMPHOPROLIFERATIVE DISORDER (PTLD) A: Two discrete gross nodules can be seen involving an extranodal site (liver, in this case). B: PTLD may appear as infiltrating collections of plump lymphocytes and plasma cells ... More about this image found in POST-TRANSPLANT LYMPHOPROLIFERATIVE DISORDER (PTLD) A: Two discrete gross ...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-08
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... the borders of the invasive carcinoma, with areas of crush artifact, zones of necrosis, and biopsy site excluded. Mononuclear cells (i.e., lymphocytes and plasma cells) should be counted, but not polymorphonuclear cells, and the entire invasive component should be evaluated, not just hotspot areas ( fig. 8-9...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch21
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... Disease Etiology Associations References AL Immunoglobulin light chain Systemic and localized Acquired Plasma cell dyscrasia ( 59 ) AH Immunoglobulin heavy chain Systemic Acquired Plasma cell dyscrasia ( 60 ) ATTR Transthyretin Systemic Acquired and hereditary ( 61 ) AA...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch27
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... in the background of dense fibrosis. Right: There are numerous IgG4-reactive plasma cells. REFERENCES REFERENCES 1. Akyuz   S , Arugaslan   E , Zengin   A , et al . Differentiation between transudate and exudate in pericardial effusion has almost no diagnostic value in contemporary medicine . Clin...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch30
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
.... Right: Higher magnification demonstrates the lymphoplasmacytic nature of the infiltrate. LYMPHOPLASMACYTIC AORTITIS Figure 30-17 LYMPHOPLASMACYTIC AORTITIS There may be areas of macrophages and occasional giant cells, in addition to lymphocytes and plasma cells, but necrotizing granulomas are absent...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch24
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... LYMPHOPROLIFERATIVE DISORDER (PTLD) Figure 24-17 POST-TRANSPLANT LYMPHOPROLIFERATIVE DISORDER (PTLD) A: Two discrete gross nodules can be seen involving an extranodal site (liver, in this case). B: PTLD may appear as infiltrating collections of plump lymphocytes and plasma cells that closely mimic rejection...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch50
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... and plasma cell granuloma, depending on the predominant histologic features. Inflammatory myofibroblastic proliferations that mimic sarcomas are particularly frequent in the urinary tract, and occur in a minority of cases after instrumentation ( 1 ). It is generally accepted that these lesions are neoplasms...