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Images
CAROTID BODY PARAGANGLIOMA A: Tumor tissue in most parts of the tumor (sam...
Available to PurchasePublished: 01 December 2024
A in this section shows many tumor cells that are negative or express only punctate staining. E: Immunoreactivity for tyrosine hydroxylase is often focally present in carotid body paragangliomas considered biochemically nonfunctional on the basis of serum or plasma assays for catecholamine metabolites. F More about this image found in CAROTID BODY PARAGANGLIOMA A: Tumor tissue in most parts of the tumor (sam...
Images
CAROTID BODY PARAGANGLIOMA A: Tumor tissue in most parts of the tumor (sam...
Available to PurchasePublished: 01 December 2024
A in this section shows many tumor cells that are negative or express only punctate staining. E: Immunoreactivity for tyrosine hydroxylase is often focally present in carotid body paragangliomas considered biochemically nonfunctional on the basis of serum or plasma assays for catecholamine metabolites. F More about this image found in CAROTID BODY PARAGANGLIOMA A: Tumor tissue in most parts of the tumor (sam...
Book Chapter
Clinicopathologic Features of the Adrenal Cortex
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-03
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... is an early feature of Cushing syndrome. Assays must be established to measure free cortisol, since the amount of cortisol-binding globulin (CBG) can also vary based on other conditions. Because the concentration of cortisol in saliva is in equilibrium with free cortisol in plasma, measurements of salivary...
Book Chapter
Adrenal Cortical Adenoma
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-05
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
..., polyuria, cramping, headaches, and weakness ( 9 ). Laboratory findings include suppressed plasma renin activity, increased plasma aldosterone levels, and a non-suppressible aldosterone level in the blood or urine. The frequency of primary hyperaldosteronism as a cause of hypertension is influenced...
Book Chapter
Pheochromocytoma and Adrenal Medullary Hyperplasia
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-08
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... exists. Biochemistry and Signaling Pathways Biochemical testing to assess catecholamine production, as discussed in chapter 1 , is the first and most definitive way of confirming the diagnosis of pheochromocytoma ( 13 ). The current technologies have moved to measurement of plasma and urinary free...
Book Chapter
Paraganglia and Paragangliomas
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-09
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
.... D: Immunostain for chromogranin A in this section shows many tumor cells that are negative or express only punctate staining. E: Immunoreactivity for tyrosine hydroxylase is often focally present in carotid body paragangliomas considered biochemically nonfunctional on the basis of serum or plasma...
Book Chapter
Adrenal Cortical Nodular Diseases
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-04
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... ). In bilateral cases, the clinical distinction of primary from secondary forms is based on the detection of low plasma ACTH levels (if oversecretion of cortisol reaches sufficient levels). Bilateral primary causes include primary bilateral macronodular adrenal disease (PBMAD, previously known as primary...
Book Chapter
Hereditary Predisposition to Adrenal Cortical Lesions
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-07
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... and biochemically indistinguishable from sporadic forms of primary hyperaldosteronism. There are no notable differences in age of disease onset, or plasma renin, serum aldosterone, or potassium levels compared to sporadic disease. It is only diagnosed based on the presence of two or more affected family members...
Book Chapter
Neuroblastoma, Ganglioneuroblastoma, and Ganglioneuroma
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-11
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... are commonly found, sometimes as a result of palisading of neuroblastic tumor cells around vessels. NBL and GNBL may present with calcification, necrosis, and hemorrhage, even in the absence of previous treatment, and sometimes inflammatory infiltrates with lymphocytes and plasma cells ( figs. 11-23 – 11-26...
Book Chapter
Physiology, Development, and Anatomy of the Adrenal Glands
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-01
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... mature adipocytes. This has been referred to as lipomatous metaplasia. Focal Lymphocytic Infiltration. Small interstitial or perivenous foci of lymphocytes and occasional plasma cells are a frequent incidental finding in the adrenal cortex and medulla. They are most common in elderly patients...
Book Chapter
Adrenal Cortical Carcinoma
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-06
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... spectrometry in patients with adrenocortical carcinoma . Horm Cancer 2016 ; 7 : 327 - 35 . 70. Schweitzer S , Kunz M , Kurlbaum M , et al . Plasma steroid metabolome profiling for the diagnosis of adrenocortical carcinoma . Eur J Endocrinol 2019 ; 180 : 117 - 25 . 71...
Images
SYPHILIS Pronounced and deep plasma cell infiltration.
Available to PurchasePublished: 01 September 2024
SYPHILIS Figure 18-3 SYPHILIS Pronounced and deep plasma cell infiltration. More about this image found in SYPHILIS Pronounced and deep plasma cell infiltration.
Images
SECONDARY SYPHILIS OF SKIN Lichenoid inflammation with prominent plasma ce...
Available to PurchasePublished: 01 September 2024
SECONDARY SYPHILIS OF SKIN Figure 18-6 SECONDARY SYPHILIS OF SKIN Lichenoid inflammation with prominent plasma cells. More about this image found in SECONDARY SYPHILIS OF SKIN Lichenoid inflammation with prominent plasma ce...
Images
ENTERIC MICROSPORIDIOSIS Prominent increase in lamina propria plasma cells...
Available to PurchasePublished: 01 September 2024
ENTERIC MICROSPORIDIOSIS Figure 22-14 ENTERIC MICROSPORIDIOSIS Prominent increase in lamina propria plasma cells, scattered intraepithelial lymphocytes, and surface epithelial disarray. Note the foci of granular supranuclear enterocyte cytoplasm (at top) due to the presence of microsporidian More about this image found in ENTERIC MICROSPORIDIOSIS Prominent increase in lamina propria plasma cells...
Images
RECTAL SYPHILIS A: Early crypt drop-out and architectural distortion, with...
Available to PurchasePublished: 01 September 2024
RECTAL SYPHILIS Figure 18-5 RECTAL SYPHILIS A: Early crypt drop-out and architectural distortion, with striking lamina propria plasma cell infiltrate. Note the focal endothelial cell swelling. B: Plasma cell infiltration is disproportionately prominent in the deep aspect of the mucosa More about this image found in RECTAL SYPHILIS A: Early crypt drop-out and architectural distortion, with...
Images
CONGENITAL SYPHILIS The wall of the intestinal tract (A) and liver (B) are...
Available to PurchasePublished: 01 September 2024
CONGENITAL SYPHILIS Figure 18-9 CONGENITAL SYPHILIS The wall of the intestinal tract (A) and liver (B) are involved. Note the scattered plasma cells. More about this image found in CONGENITAL SYPHILIS The wall of the intestinal tract (A) and liver (B) are...
Images
CUTANEOUS LEISHMANIA ULCER Prominent peripheralization of...
Available to PurchasePublished: 01 September 2024
CUTANEOUS LEISHMANIA ULCER Figure 28-5 CUTANEOUS LEISHMANIA ULCER Prominent peripheralization of amastigotes within macrophages, with prominent histiocytes and plasma cells (A,B). More about this image found in CUTANEOUS LEISHMANIA ULCER Prominent peripheralization of...
Images
SECONDARY SYPHILIS INVOLVING A LYMPH NODE Endothelial cell swelling, plasm...
Available to PurchasePublished: 01 September 2024
SECONDARY SYPHILIS INVOLVING A LYMPH NODE Figure 18-7 SECONDARY SYPHILIS INVOLVING A LYMPH NODE Endothelial cell swelling, plasma cell infiltration (A), and early granuloma formation (B). More about this image found in SECONDARY SYPHILIS INVOLVING A LYMPH NODE Endothelial cell swelling, plasm...
Images
TYPHOID FEVER A,B: Extensive necrosis and deep ulceration extending to the...
Available to PurchasePublished: 01 September 2024
TYPHOID FEVER Figure 13-16 TYPHOID FEVER A,B: Extensive necrosis and deep ulceration extending to the muscularis propria are features. Note the prominent lymphohistiocytic infiltrate and the near absence of neutrophils. C: Scant plasma cells are present in the adjacent intact mucosa. More about this image found in TYPHOID FEVER A,B: Extensive necrosis and deep ulceration extending to the...
Images
EBV-ASSOCIATED INFECTIOUS MONONUCLEOSIS Lymph node with architectural dist...
Available to PurchasePublished: 01 September 2024
EBV-ASSOCIATED INFECTIOUS MONONUCLEOSIS Figure 8-8 EBV-ASSOCIATED INFECTIOUS MONONUCLEOSIS Lymph node with architectural distortion (A) with focal capsular permeation by lymphoid cells (top), a polymorphic mononuclear infiltrate (B) with associated plasma cells (C) and focal mitotic activity More about this image found in EBV-ASSOCIATED INFECTIOUS MONONUCLEOSIS Lymph node with architectural dist...
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