ETIOLOGY OF NONIATROGENIC ACTH-DEPENDENT CUSHING SYNDROME Figure 3-2 ETIOLOGY OF NONIATROGENIC ACTH-DEPENDENT CUSHING SYNDROME Normal hypothalamic-pituitary-adrenal axis (upper left), pituitary-dependent Cushing disease (upper right), and ectopic ACTH syndrome. More about this image found in ETIOLOGY OF NONIATROGENIC ACTH-DEPENDENT CUSHING SYNDROME Normal hypothala...

CUSHING DISEASE Figure 3-12 CUSHING DISEASE Bilateral adrenal hyperplasia in a patient with ACTH-secreting pituitary tumor. There is mild and micronodular increase in size in the left (A) and right (B) adrenal glands. The right gland also has a macronodule (over 1 cm). More about this image found in CUSHING DISEASE Bilateral adrenal hyperplasia in a patient with ACTH-secre...

CUSHING DISEASE Figure 3-3 CUSHING DISEASE Bilateral adrenal hyperplasia is seen by computerized tomography (CT) in a patient with an ACTH-dependent, recurrent ACTH-secreting pituitary tumor. (Courtesy of Prof. A. Veltri and Dr. F. Solitro, San Luigi Hospital, Turin, Italy) More about this image found in CUSHING DISEASE Bilateral adrenal hyperplasia is seen by computerized tomo...

CUSHING DISEASE Figure 3-8 CUSHING DISEASE Histology of left (upper panels) and right (lower panels) adrenal glands from a patient with a recurrent ACTH-secreting pituitary tumor (same case as fig. 3-3 ). Both glands show a similar morphologic appearance, with a homogeneous increase of cortical ... More about this image found in CUSHING DISEASE Histology of left (upper panels) and right (lower panels) ...

CUSHING DISEASE WITH DIFFUSE AND MICRONODULAR HYPERPLASIA Figure 3-5 CUSHING DISEASE WITH DIFFUSE AND MICRONODULAR HYPERPLASIA Transverse sections of adrenal gland in a patient with pituitary ACTH-dependent hypercortisolism (Cushing disease). The adrenal gland was only mildly enlarged and shows b... More about this image found in CUSHING DISEASE WITH DIFFUSE AND MICRONODULAR HYPERPLASIA Transverse secti...

CUSHING SYNDROME Figure 3-1 CUSHING SYNDROME The clinical features of this disorder (left) can be caused by pituitary adrenocorticotropic hormone (ACTH) excess (top right), ectopic ACTH causing massive adrenal hyperplasia (right middle), or primary adrenal disease (bottom right). (From Netter FH.... More about this image found in CUSHING SYNDROME The clinical features of this disorder (left) can be caus...

USE OF SPECIAL STAINS IN THE DIAGNOSIS OF INFECTIOUS DISEASES Figure 1-2 USE OF SPECIAL STAINS IN THE DIAGNOSIS OF INFECTIOUS DISEASES A,B: Bone marrow H&E (A) and Grocott methenamine silver (B) stains. The latter shows numerous budding Histoplasma capsulatum yeasts. C–E: H&E stain (C,D) on a pituitary gland specimen showing histologic findings suspicious for tissue pathogens. A strongly positive von Kossa calcium stain (E), however, confirms the suspicious deposits as calcifications and excludes infectious microorganisms. More about this image found in USE OF SPECIAL STAINS IN THE DIAGNOSIS OF INFECTIOUS DISEASES A,B: Bone ma...