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FIBRINOUS PERICARDITIS: <span class="search-highlight">PHASES</span> OF ORGANIZATION  Left: The acute <span class="search-highlight">phase</span> of or...
Published: 15 November 2023
FIBRINOUS PERICARDITIS: PHASES OF ORGANIZATION Figure 27-11 FIBRINOUS PERICARDITIS: PHASES OF ORGANIZATION Left: The acute phase of organizing fibrinous pericarditis contains exuberant fibrinous exudate. Right: Chronically, the exudate organizes and becomes fibrotic, with perpendicularly oriente... More about this image found in FIBRINOUS PERICARDITIS: PHASES OF ORGANIZATION Left: The acute phase of or...
Images
GRANULOMATOUS AORTITIS: ACTIVE <span class="search-highlight">PHASE</span>  The areas of necrosis are surrounded ...
Published: 15 November 2023
GRANULOMATOUS AORTITIS: ACTIVE PHASE Figure 30-15 GRANULOMATOUS AORTITIS: ACTIVE PHASE The areas of necrosis are surrounded by chronic inflammation with granulation tissue that is evident with both hematoxylin and eosin (H&E) staining (top) and elastic staining (bottom). More about this image found in GRANULOMATOUS AORTITIS: ACTIVE PHASE The areas of necrosis are surrounded ...
Images
KAWASAKI DISEASE: ACUTE <span class="search-highlight">PHASE</span>  The coronary artery is involved by an exuber...
Published: 15 November 2023
KAWASAKI DISEASE: ACUTE PHASE Figure 6-3 KAWASAKI DISEASE: ACUTE PHASE The coronary artery is involved by an exuberant lymphocytic infiltrate that involves all layers of the vessel wall, with focal areas of complete medial loss (black arrow) (left), further highlighted by an elastic stain (right)... More about this image found in KAWASAKI DISEASE: ACUTE PHASE The coronary artery is involved by an exuber...
Images
KAWASAKI DISEASE: CHRONIC <span class="search-highlight">PHASE</span>  There is marked intimal thickening and org...
Published: 15 November 2023
KAWASAKI DISEASE: CHRONIC PHASE Figure 6-4 KAWASAKI DISEASE: CHRONIC PHASE There is marked intimal thickening and organized thrombotic luminal occlusion with recanalization. Areas of the media are markedly attenuated around the circumference of the artery. (Elastic stain.) More about this image found in KAWASAKI DISEASE: CHRONIC PHASE There is marked intimal thickening and org...
Images
KAWASAKI DISEASE: CHRONIC <span class="search-highlight">PHASE</span>  Left: The elastic layer is focally lost (b...
Published: 15 November 2023
KAWASAKI DISEASE: CHRONIC PHASE Figure 6-5 KAWASAKI DISEASE: CHRONIC PHASE Left: The elastic layer is focally lost (black arrowhead) and there is medial loss with marked intimal fibroplasia. (Elastic stain.) Right: The intimal fibroplasia has a vague tissue culture-like appearance. More about this image found in KAWASAKI DISEASE: CHRONIC PHASE Left: The elastic layer is focally lost (b...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-06
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
...   2011 ; 365 : 1448 . 25. McArthur   GA , Chapman   PB , Robert   C , et al . Safety and efficacy of vemurafenib in BRAF(V600E) and BRAF(V600K) mutation-positive melanoma (BRIM-3): extended follow-up of a phase 3, randomised, open-label study . Lancet Oncol   2014 ; 15 : 323 - 32...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-03
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... clear cytoplasm (arrows). Most common acquired or intradermal melanocytic nevi lack mitotic figures. However, some can be seen in an active growth phase, such as during childhood or in pregnancy ( fig. 3-17 ) ( 15 ). When mitoses are present in a nevus, they are typically located in the superficial...
Images
CARDIOTOXICITY: DOXORUBICIN  Biventricular dilatation, similar to dilated c...
Published: 15 November 2023
CARDIOTOXICITY: DOXORUBICIN Figure 23-6 CARDIOTOXICITY: DOXORUBICIN Biventricular dilatation, similar to dilated cardiomyopathy, is frequently seen in both the acute and chronic phases of this toxicity. More about this image found in CARDIOTOXICITY: DOXORUBICIN Biventricular dilatation, similar to dilated c...
Images
SUBACUTE MYOCARDIAL INFARCTION: GRANULATION TISSUE  Small capillaries and f...
Published: 15 November 2023
SUBACUTE MYOCARDIAL INFARCTION: GRANULATION TISSUE Figure 7-16 SUBACUTE MYOCARDIAL INFARCTION: GRANULATION TISSUE Small capillaries and fibroblasts indicate the healing phase is now occurring. More about this image found in SUBACUTE MYOCARDIAL INFARCTION: GRANULATION TISSUE Small capillaries and f...
Images
MICROFOCAL NECROSIS  Top: Empty shells of necrotic myocytes, surrounded by ...
Published: 15 November 2023
MICROFOCAL NECROSIS Figure 4-16 MICROFOCAL NECROSIS Top: Empty shells of necrotic myocytes, surrounded by a mild infiltrate containing histiocytes, due to chronic subendocardial ischemic injury. Bottom: Histiocytes with hemosiderin from myoglobin and hemoglobin released from dead/dying cells, in... More about this image found in MICROFOCAL NECROSIS Top: Empty shells of necrotic myocytes, surrounded by ...
Images
INTERSTITIAL FIBROSIS: SPECTRUM  A: Mild endomysial fibrosis (around indivi...
Published: 15 November 2023
INTERSTITIAL FIBROSIS: SPECTRUM Figure 4-8 INTERSTITIAL FIBROSIS: SPECTRUM A: Mild endomysial fibrosis (around individual myocytes) and perimysial fibrosis (around small groups of myocytes). B,C: Interstitial fibrosis of combined pericellular and replacement types. D: Prominent subendocardial p... More about this image found in INTERSTITIAL FIBROSIS: SPECTRUM A: Mild endomysial fibrosis (around indivi...
Images
CHRONIC PULMONARY THROMBOEMBOLIC DISEASE  A: Eccentric intimal pads may rep...
Published: 15 November 2023
CHRONIC PULMONARY THROMBOEMBOLIC DISEASE Figure 32-19 CHRONIC PULMONARY THROMBOEMBOLIC DISEASE A: Eccentric intimal pads may represent the sequelae of organized thromboemboli in small vessels or in situ thrombosis on elastic tissue stain. B: Subtle arterial webbing represents old, partially lyse... More about this image found in CHRONIC PULMONARY THROMBOEMBOLIC DISEASE A: Eccentric intimal pads may rep...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-01
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... cells in both the terminal duct and lobule undergo secretory changes and show a high level of proliferative activity ( 24 ). These different phases in the life cycle correspond to four lobule types (types 1 to 4) ( 25 – 27 ): type 1 lobules, present in prepubertal and nulliparous women, are the most...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-11
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... for advanced disease . Oncologist   2011 ; 16 : 682 - 93 . 23. Kasper   B , Gruenwald   V , Reichardt   P , et al . Imatinib induces sustained progression arrest in RECIST progressive desmoid tumours: final results of a phase II study of the German Interdisciplinary Sarcoma Group (GISG...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-15
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... , van Tienhoven   G , Straver   ME , et al . Radiotherapy or surgery of the axilla after a positive sentinel node in breast cancer (EORTC 10981-22023 AMAROS): a randomised, multi-centre, open-label, phase 3 non-inferiority trial . Lancet Oncol   2014 ; 15 : 1303 - 10 . 68. Grabenstetter...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-03
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... trial (SweDCIS) . Cancers (Basel)   2021 ; 13 : 6103 . 87. Hwang   ES , Hyslop   T , Lynch   T , et al . The COMET (Comparison of Operative versus Monitoring and Endocrine Therapy) trial: a phase III randomised controlled clinical trial for low-risk ductal carcinoma in situ (DCIS...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-08
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... lymphocytes (TILs) are a powerful prognostic marker in patients with triple-negative breast cancer enrolled in the IBCSG phase III randomized clinical trial 22-00 . Breast Cancer Res Treat   2016 ; 158 : 323 - 31 . 50. Denkert   C . Diagnostic and therapeutic implications of tumor-infiltrating...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch16
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... inflammation, and prominent giant cells. Treatment. Treatment is dependent on the disease stage. In the acute phase, steroids are helpful in controlling the eosinophilia and, if caught early, can mitigate the cardiac complications of the disease. Therapy can then be undertaken to target the root...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch27
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... PERICARDITIS Figure 27-10 UREMIC PERICARDITIS Uremic pericarditis is virtually indistinguishable from idiopathic fibrinous pericarditis. FIBRINOUS PERICARDITIS: PHASES OF ORGANIZATION Figure 27-11 FIBRINOUS PERICARDITIS: PHASES OF ORGANIZATION Left: The acute phase of organizing fibrinous pericarditis...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch06
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
.... KAWASAKI DISEASE: ACUTE PHASE Figure 6-3 KAWASAKI DISEASE: ACUTE PHASE The coronary artery is involved by an exuberant lymphocytic infiltrate that involves all layers of the vessel wall, with focal areas of complete medial loss (black arrow) (left), further highlighted by an elastic stain (right...