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Images
in Congenital Disorders of the Adrenal Gland
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
due to intense persistent stimulation by adrenocorticotropic hormone (ACTH). More about this image found in CONGENITAL ADRENAL HYPERPLASIA Autopsy of an infant who died of the severe...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-02
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... due to intense persistent stimulation by adrenocorticotropic hormone (ACTH). In CAH, intense persistent trophic stimulation by adrenocorticotropic hormone (ACTH) results in marked hyperplasia of the zona fasciculata with conversion of pale-staining, lipid-rich cells into lipid-depleted cells...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-09
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... paraganglia persist in adults ( 12 ) and are often found incidentally in microscopic sections taken in or near abdominal, pelvic, and thoracic organs. In some locations, such as the genitourinary tract, they are diagnostic pitfalls, potentially mistaken for carcinoma ( fig. 9-6 ) ( 13 ). NORMAL ABDOMINAL...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-08
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... ). The most diagnostic features are paroxysmal episodes of tachycardia, diaphoresis, pallor, headache, and anxiety as well as hypertension that can be more persistent. Sustained hypertension is reflective of noradrenaline (norepinephrine) secretion whereas tumors with predominant adrenaline (epinephrine...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-11
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
..., interleukin-2, and isotretinoin for neuroblastoma . N Engl J Med 2010 ; 363 : 1324 - 34 . 87. Pule MA , Savoldo B , Myers GD , et al . Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma . Nat...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-12
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... on color Doppler ultrasound, and evolving complex architecture all favor neuroblastoma ( 79 ). Initial clinical management is usually conservative, but many patients eventually undergo interval adrenalectomy either because of persistent symptoms or concern for possible neoplasia ( 77 ). Over time, benign...
Images
Published: 01 September 2024
PERSISTENT GENERALIZED LYMPHADENOPATHY (PGL) Figure 9-2 PERSISTENT GENERALIZED LYMPHADENOPATHY (PGL) A: The lymph node has irregularly shaped reactive follicles. B: PGL lymph node follicle in center with macrophage phagocytosis and apoptotic debris. C: HIVp24 stains HIV virus in follicular More about this image found in PERSISTENT GENERALIZED LYMPHADENOPATHY (PGL) A: The lymph node has irregul...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-08
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... A , Ionescu D , Melhem M . Parvovirus B19 infection in the immunocompromised host . Arch Pathol Lab Med 2007 ; 131 : 799 - 804 . 11. Söderlund-Venermo M , Hokynar K , Nieminen J , Rautakorpi H , Hedman K . Persistence of human parvovirus B19 in human tissues...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-10
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., Lassa virus is considered a category A select agent. Lassa virus infection begins with viral glycoprotein attachment to dystroglycan on the host cell surface, inducing macropinocytosis. This interaction causes minimal perturbation in the host cell, allowing the virus to have a nonlytic persistent life...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-07
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... Subsequent Biopsy Ongoing Persistent inflammation, with/without fibrosis Resolving Persistent inflammation, with/without fibrosis Healed/resolved Myocarditis, with/without fibrosis THE DIFFERENT STAGES OF MYOCARDITIS Figure 7-1 THE DIFFERENT STAGES OF MYOCARDITIS ENTEROVIRUS MYOCARDITIS...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-27
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... frequent tissue encountered by the histopathologist, particularly in patients with severe disease. Usually, there is splenomegaly and, if rupture has occurred, hematomas may form at the rupture site. Microscopically, there is red pulp expansion and erythrophagocytosis ( 17 ). In patients with persistent...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-09
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... and Immunology) PERSISTENT GENERALIZED LYMPHADENOPATHY (PGL) Figure 9-2 PERSISTENT GENERALIZED LYMPHADENOPATHY (PGL) A: The lymph node has irregularly shaped reactive follicles. B: PGL lymph node follicle in center with macrophage phagocytosis and apoptotic debris. C: HIVp24 stains HIV virus in follicular...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-17
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... have also occasionally been implicated in transmitting these same species. The subsequent pathogenesis of infection relies on a complex process that includes host immune evasion and modulation, intimate interaction with nucleated cells, and persistence in erythrocytes ( 1 ). Bartonella spp...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-19
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... (GMS) stain, however, the cell wall of the mother and daughter cell is thinner than the separating wall (which is typically double the thickness) ( fig. 19-7 ) ( 3 ). Another example of a recently delineated fungal species characterized by resistance to antimycotic agents and persistence...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-29
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., transforming into amastigotes. Amastigotes are found in many tissues, but they have a predilection for muscle. Several mechanisms have been proposed for the pathogenesis of chronic disease. These include parasite persistence with a specific parasite-immune response and parasite-induced cell lysis, parasite...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-30
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... can persist for many years and is much more frequently symptomatic. Although other STDs are usually most prevalent in adolescent and young adult women, trichomoniasis is notable in that it also commonly affects older women. T. vaginalis causes disease by altering the normal vaginal microbiota...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-03
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
...; cytoplasmic-basophilic granular inclusions) Human herpesvirus (HHV)-6 (roseola infantum) Worldwide Febrile seizures in children Post-transplant limbic encephalitis in adults Virus persists in T lymphocytes and brain without causing particular pathology or cytopathic effect Human immunodeficiency...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-13
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... the organism is typically acquired in childhood and persists for many years (frequently for life). High-income countries have seen a steady decrease in the prevalence of H. pylori infection over the last few decades, largely due to improved sanitation and increased use of antibiotics for other...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-05
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... Med Virol 1979 ; 3 : 237 - 41 . 8. Alter HJ , Seeff LB . Recovery, persistence, and sequelae in hepatitis C virus infection: a perspective on long-term outcome . Semin Liver Dis 2000 ; 20 : 17 - 35 . 9. Freeman AJ , Dore GJ , Law MG , et al . Estimating...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-04
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... review . Mod Pathol 2021 ; 34 : 1614 - 33 . 19. Ravaglia C , Doglioni C , Chilosi M , et al . Clinical, radiological and pathological findings in patients with persistent lung disease following SARS-CoV-2 infection . Eur Respir J 2022 ; 60 : 2102411 . 20. Bradley B...
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