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Images
Figure 9-9

ECTOPIC PARATHYROID TISSUE WITHIN VAGUS NERVE Non-neoplastic ectopic parat...

in Paraganglia and Paragangliomas > Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
ECTOPIC PARATHYROID TISSUE WITHIN VAGUS NERVE Figure 9-9 ECTOPIC PARATHYROID TISSUE WITHIN VAGUS NERVE Non-neoplastic ectopic parathyroid tissue and parathyroid adenomas within the vagus, as in this example, are potentially mistaken for vagal paraganglia and paragangliomas. More about this image found in ECTOPIC PARATHYROID TISSUE WITHIN VAGUS NERVE Non-neoplastic ectopic parat...
Images
Figure 10-7

PHEOCHROMOCYTOMA IN A PATIENT WITH MEN1 This adrenal pheochromocytoma was ...

in Familial and Syndrome-Related Pheochromocytoma and Paraganglioma > Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
PHEOCHROMOCYTOMA IN A PATIENT WITH MEN1 Figure 10-7 PHEOCHROMOCYTOMA IN A PATIENT WITH MEN1 This adrenal pheochromocytoma was identified at the time of surgery for a pancreatic neuroendocrine tumor in a patient with a history of multi-glandular parathyroid disease. While the tumor has More about this image found in PHEOCHROMOCYTOMA IN A PATIENT WITH MEN1 This adrenal pheochromocytoma was ...
Book Chapter

Paraganglia and Paragangliomas

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-09
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... paraganglia and paragangliomas in the head and neck is the presence of ectopic, hyperplastic, or neoplastic parathyroid tissue ( figs. 9-8 – 9-10 ). NORMAL CAROTID BODY Figure 9-7 NORMAL CAROTID BODY A: This developing carotid body in an early second trimester stillborn fetus (same case as in figs. 9-3...
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Book Chapter

Familial and Syndrome-Related Pheochromocytoma and Paraganglioma

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-10
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... Locations Cluster Other Associated Lesions RET 10q11.2 MEN2 (multiple endocrine neoplasia type 2) Adrenal 2 Medullary thyroid carcinoma; parathyroid hyperplasia or neoplasia Mucocutaneous ganglioneuromas (MEN2B) NF1 17q11.2 NF1 (neurofibromatosis type 1) Adrenal (rarely...
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Book Chapter

Hereditary Predisposition to Adrenal Cortical Lesions

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-07
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
...) MEN1 Primary macronodular adrenal disease, adenoma, carcinoma <2% Parathyroid hyperplasia/adenoma, pituitary tumors, foregut neuroendocrine tumors Familial adenomatous polyposis (FAP) APC Adenoma, primary macronodular adrenal disease and carcinoma <1% Colon carcinoma, duodenal...
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Book Chapter

Pheochromocytoma and Adrenal Medullary Hyperplasia

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-08
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
...; while this biomarker is expressed in many nonendocrine tissues, the only other neuroendocrine cells that express GATA3 are normal and neoplastic parathyroid and pituitary cells. The most specific markers are cytoplasmic tyrosine hydroxylase ( fig. 8-38 ) and other catecholamine pathway enzymes...
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Book Chapter

Conotruncal Anomalies

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch37
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... the DiGeorge syndrome. These are often associated with an interrupted aortic arch, right aortic arch, or abnormal aortic arch branch. Extracardiac anomalies are common and include thymic and parathyroid hypoplasia, cleft palate, and facial dysmorphism ( 15 ). Less frequently, other syndromes occur, including...
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Book Chapter

Parathyroid Gland

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 13
Published: 01 November 2022
10.55418/9781933477251-2
ISBN-10: 1-933477-25-3
ISBN: 978-1-933477-25-1
... Multiglandular parathyroid disease is most common manifestation of MEN1 (also adenomas and carcinomas) Other manifestations include PitNETs, pancreatic endocrine tumors, neuroendocrine (NE) tumors of duodenum, gastrinomas, NE tumors of thymus and lung, adrenal cortical adenomas, and hyperplasia Multiple...
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Images
Figure 2-18

PARATHYROID CYST Left: Parathyroid cysts may have parathyroid cells in the...

in Parathyroid Gland > Non-Neoplastic Disorders of the Endocrine System
Published: 01 November 2022
PARATHYROID CYST Figure 2-18 PARATHYROID CYST Left: Parathyroid cysts may have parathyroid cells in the cyst wall. Right: The cyst wall is usually thin and fibrous, but may also contain other elements such lymphoid, muscular, thymic, salivary, adipose, and mesenchymal tissue. More about this image found in PARATHYROID CYST Left: Parathyroid cysts may have parathyroid cells in the...
Images
Figure 2-1

PARATHYROID GLAND Parathyroid glands are composed of parenchymal cells and...

in Parathyroid Gland > Non-Neoplastic Disorders of the Endocrine System
Published: 01 November 2022
PARATHYROID GLAND Figure 2-1 PARATHYROID GLAND Parathyroid glands are composed of parenchymal cells and adipose tissue. Parenchymal cells include chief cells, oncocytic/oxyphilic cells, transitional cells, and clear (water clear) cells; mixtures of cell types can be seen (A–D). Parathyroid More about this image found in PARATHYROID GLAND Parathyroid glands are composed of parenchymal cells and...
Images
Figure 2-6

PARATHYROID HYPERPLASIA There are many growth patterns in parathyroid hype...

in Parathyroid Gland > Non-Neoplastic Disorders of the Endocrine System
Published: 01 November 2022
PARATHYROID HYPERPLASIA Figure 2-6 PARATHYROID HYPERPLASIA There are many growth patterns in parathyroid hyperplasia including sheet-like growth, acinar growth, follicular growth, nests, glandular formations, cords, palisading of cells, papillary growth, microcysts, and cribriform growth More about this image found in PARATHYROID HYPERPLASIA There are many growth patterns in parathyroid hype...
Images
Figure 2-6

PARATHYROID HYPERPLASIA There are many growth patterns in parathyroid hype...

in Parathyroid Gland > Non-Neoplastic Disorders of the Endocrine System
Published: 01 November 2022
PARATHYROID HYPERPLASIA Figure 2-6 PARATHYROID HYPERPLASIA There are many growth patterns in parathyroid hyperplasia including sheet-like growth, acinar growth, follicular growth, nests, glandular formations, cords, palisading of cells, papillary growth, microcysts, and cribriform growth More about this image found in PARATHYROID HYPERPLASIA There are many growth patterns in parathyroid hype...
Images
Figure 2-7

PARATHYROID HYPERPLASIA These parathyroid glands show degenerative edemato...

in Parathyroid Gland > Non-Neoplastic Disorders of the Endocrine System
Published: 01 November 2022
PARATHYROID HYPERPLASIA Figure 2-7 PARATHYROID HYPERPLASIA These parathyroid glands show degenerative edematous changes (left, right). More about this image found in PARATHYROID HYPERPLASIA These parathyroid glands show degenerative edemato...
Images
Figure 2-8

HYPERCELLULAR PARATHYROID GLAND: CYSTIC CHANGE The parathyroid glands can ...

in Parathyroid Gland > Non-Neoplastic Disorders of the Endocrine System
Published: 01 November 2022
HYPERCELLULAR PARATHYROID GLAND: CYSTIC CHANGE Figure 2-8 HYPERCELLULAR PARATHYROID GLAND: CYSTIC CHANGE The parathyroid glands can show hemorrhage and cystic change, particularly in larger glands and in those with hyperparathyroidism-jaw tumor–associated disease more so than sporadic More about this image found in HYPERCELLULAR PARATHYROID GLAND: CYSTIC CHANGE The parathyroid glands can ...
Images
Figure 2-9

HYPERCELLULAR PARATHYROID TISSUE: HEMOSIDERIN Parathyroid gland showing he...

in Parathyroid Gland > Non-Neoplastic Disorders of the Endocrine System
Published: 01 November 2022
HYPERCELLULAR PARATHYROID TISSUE: HEMOSIDERIN Figure 2-9 HYPERCELLULAR PARATHYROID TISSUE: HEMOSIDERIN Parathyroid gland showing hemorrhage and hemosiderin deposition (left, right). More about this image found in HYPERCELLULAR PARATHYROID TISSUE: HEMOSIDERIN Parathyroid gland showing he...
Images
Figure 2-10

PARATHYROID LIPOHYPERPLASIA Left: Parathyroid lipohyperplasia is an uncomm...

in Parathyroid Gland > Non-Neoplastic Disorders of the Endocrine System
Published: 01 November 2022
PARATHYROID LIPOHYPERPLASIA Figure 2-10 PARATHYROID LIPOHYPERPLASIA Left: Parathyroid lipohyperplasia is an uncommon type of parathyroid hyperplasia in which multiple parathyroid glands show abundant mature adipose tissue with only scattered nests of parenchyma involving multiple hyperfunctional More about this image found in PARATHYROID LIPOHYPERPLASIA Left: Parathyroid lipohyperplasia is an uncomm...
Images
Figure 2-11

CLEAR CELL PARATHYROID HYPERPLASIA Clear cell parathyroid hyperplasia is a...

in Parathyroid Gland > Non-Neoplastic Disorders of the Endocrine System
Published: 01 November 2022
CLEAR CELL PARATHYROID HYPERPLASIA Figure 2-11 CLEAR CELL PARATHYROID HYPERPLASIA Clear cell parathyroid hyperplasia is an absolute increase in parathyroid parenchymal cells with abundant clear cytoplasm involving multiple parathyroid glands in the absence of a known stimulus for parathyroid More about this image found in CLEAR CELL PARATHYROID HYPERPLASIA Clear cell parathyroid hyperplasia is a...
Images
Figure 2-13

SECONDARY PARATHYROID HYPERPLASIA Although the parathyroid glands in secon...

in Parathyroid Gland > Non-Neoplastic Disorders of the Endocrine System
Published: 01 November 2022
SECONDARY PARATHYROID HYPERPLASIA Figure 2-13 SECONDARY PARATHYROID HYPERPLASIA Although the parathyroid glands in secondary hyperparathyroidism may show diffuse growth early in disease, they become more nodular over time. A,B: Nodular growth of secondary parathyroid hyperplasia. C,D More about this image found in SECONDARY PARATHYROID HYPERPLASIA Although the parathyroid glands in secon...
Images
Figure 2-17

PARATHYROID CYST Parathyroid cysts are rare and may be incidental findings...

in Parathyroid Gland > Non-Neoplastic Disorders of the Endocrine System
Published: 01 November 2022
PARATHYROID CYST Figure 2-17 PARATHYROID CYST Parathyroid cysts are rare and may be incidental findings or clinically apparent as a mass that is confused with a thyroid nodule. Left: Parathyroid cysts are lined by flattened parathyroid epithelial cells that are positive for parathyroid hormone More about this image found in PARATHYROID CYST Parathyroid cysts are rare and may be incidental findings...
Images
Figure 2-19

PARATHYROID AMYLOID Amyloid is identified in parathyroid glands in the set...

in Parathyroid Gland > Non-Neoplastic Disorders of the Endocrine System
Published: 01 November 2022
PARATHYROID AMYLOID Figure 2-19 PARATHYROID AMYLOID Amyloid is identified in parathyroid glands in the setting of systemic amyloidosis, but it can also be identified in individuals without systemic amyloidosis. Left, right: Extensive involvement of the parathyroid gland by amyloid. More about this image found in PARATHYROID AMYLOID Amyloid is identified in parathyroid glands in the set...