MPOX Figure 6-11 MPOX Microscopic features of skin lesions. (Courtesy of the CDC IDPB) A: Early changes showing a lichenoid papillary dermal and perivascular mixed inflammatory cell infiltrate, which includes lymphocytes, macrophages, and rare eosinophils. Single dyskeratotic cells are visible i... More about this image found in MPOX Microscopic features of skin lesions. (Courtesy of the CDC IDPB) A: ...

MPOX Figure 6-11 MPOX Microscopic features of skin lesions. (Courtesy of the CDC IDPB) A: Early changes showing a lichenoid papillary dermal and perivascular mixed inflammatory cell infiltrate, which includes lymphocytes, macrophages, and rare eosinophils. Single dyskeratotic cells are visible i... More about this image found in MPOX Microscopic features of skin lesions. (Courtesy of the CDC IDPB) A: ...

LSIL Figure 9-36 LSIL A: A normal intermediate cell is indicated (arrow). Other cells show features of LSIL with nuclear enlargement, coarse chromatin, nuclear membrane irregularities, perinuclear halo (“koilocyte”), and multinucleation (SurePath cytology, Papanicolaou stain). B: Condyloma with ... More about this image found in LSIL A: A normal intermediate cell is indicated (arrow). Other cells show ...

HSIL AND CARCINOMA Figure 9-37 HSIL AND CARCINOMA A: Cohesive and singly scattered hyperchromatic cells, with high nuclear to cytoplasmic ratio, coarse chromatin, and nuclear irregularity (SurePath cytology, Papanicolaou stain). B: HSIL with acanthosis, hyperkeratosis (at left), parakeratosis (a... More about this image found in HSIL AND CARCINOMA A: Cohesive and singly scattered hyperchromatic cells, ...

HSIL AND CARCINOMA Figure 9-37 HSIL AND CARCINOMA A: Cohesive and singly scattered hyperchromatic cells, with high nuclear to cytoplasmic ratio, coarse chromatin, and nuclear irregularity (SurePath cytology, Papanicolaou stain). B: HSIL with acanthosis, hyperkeratosis (at left), parakeratosis (a... More about this image found in HSIL AND CARCINOMA A: Cohesive and singly scattered hyperchromatic cells, ...

DEEP PENETRATING NEVUS ASSOCIATED WITH A CONVENTIONAL NEVUS (COMBINED NEVUS) Figure 9-4 DEEP PENETRATING NEVUS ASSOCIATED WITH A CONVENTIONAL NEVUS (COMBINED NEVUS) This lesion is limited to the papillary and superficial reticular dermis. More about this image found in DEEP PENETRATING NEVUS ASSOCIATED WITH A CONVENTIONAL NEVUS (COMBINED NEVUS...

LENTIGO MALIGNA MELANOMA WITH SINGLE CELL MICROINVASION Figure 13-11 LENTIGO MALIGNA MELANOMA WITH SINGLE CELL MICROINVASION Melanoma in situ is associated with isolated atypical melanocytes (arrows) in a fibrosed papillary dermis. More about this image found in LENTIGO MALIGNA MELANOMA WITH SINGLE CELL MICROINVASION Melanoma in situ i...

LENTIGO MALIGNA MELANOMA IN SITU Figure 13-4 LENTIGO MALIGNA MELANOMA IN SITU There is an increased density of solitary units of melanocytes at the dermoepidermal junction. The melanocytes also display cytologic atypia: their nuclei are larger and more hyperchromatic than the nuclei of adjacent k... More about this image found in LENTIGO MALIGNA MELANOMA IN SITU There is an increased density of solitary...

NEVOID MELANOMA Figure 17-6 NEVOID MELANOMA A: Plaque-like silhouette of the tumor simulates the appearance of a small congenital nevus. Several thin elongated rete ridges are present. B: The papillary dermis contains dense aggregates of melanocytes, some of which have enlarged nuclei. C: Mitot... More about this image found in NEVOID MELANOMA A: Plaque-like silhouette of the tumor simulates the appea...

POLYPOID COMPOUND (UNNA) MELANOCYTIC NEVUS Figure 3-6 POLYPOID COMPOUND (UNNA) MELANOCYTIC NEVUS A: There is an exophytic nodule with a papillomatous surface. The papillary dermis is expanded and filled with small epithelioid intradermal melanocytes. The polypoid component is surrounded by a smal... More about this image found in POLYPOID COMPOUND (UNNA) MELANOCYTIC NEVUS A: There is an exophytic nodule...

PIGMENTED EPITHELIOID MELANOCYTOMA Figure 11-2 PIGMENTED EPITHELIOID MELANOCYTOMA A: Silhouette of a heavily pigmented intradermal tumor from the shoulder of a 15-year-old boy. B: Junctional melanocytes are present, and many tumor cells involve both the papillary and reticular dermis. There is a... More about this image found in PIGMENTED EPITHELIOID MELANOCYTOMA A: Silhouette of a heavily pigmented in...

LENTIGO MALIGNA MELANOMA IN SITU Figure 13-2 LENTIGO MALIGNA MELANOMA IN SITU A: There is a broad pigmented macular process. The epidermis shows lentigo-like features with hyperpigmentation of keratinocytes and focal slight elongation of rete ridges. Melanophages are present in the slightly fibro... More about this image found in LENTIGO MALIGNA MELANOMA IN SITU A: There is a broad pigmented macular pro...

PAPILLARY LESION WITH INFARCTION Figure 7-8 PAPILLARY LESION WITH INFARCTION A: At low power, an area of papillary ductal carcinoma in situ (DCIS) is apparent at the right of the field, beside which is a needle biopsy tract with an adjacent area of necrosis. B: At higher power, the “ghosts” of f... More about this image found in PAPILLARY LESION WITH INFARCTION A: At low power, an area of papillary duc...