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Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-5
ISBN: 978-1-933477-61-9
..., vertebral anomalies such as hemivertebrae, fusion or elongation of the vertebral bodies, modeling defects of the hands and feet  Cleft lip or palate, polydactyly  Cardiac or ovarian fibroma  Medulloblastoma  Other skeletal abnormalities: Sprengel deformity, marked pectus deformity, marked...
Images
Figure 1-36
Published: 01 December 2024
OVARIAN THECAL METAPLASIA Figure 1-36 OVARIAN THECAL METAPLASIA Ovarian thecal metaplasia appears as a broad zone of bland spindle cells. Nests of pale-staining cortical cells are present within the spindle cell component. More about this image found in OVARIAN THECAL METAPLASIA Ovarian thecal metaplasia appears as a broad zon...
Images
Figure 2-9
Published: 01 December 2024
ACCESSORY ADRENAL CORTICAL TISSUE WITH OVARIAN THECAL METAPLASIA Figure 2-9 ACCESSORY ADRENAL CORTICAL TISSUE WITH OVARIAN THECAL METAPLASIA A: The heterotopic adrenal cortical rest was located near the broad ligament in an adult woman. Cortical cells are present in the center of the nodule More about this image found in ACCESSORY ADRENAL CORTICAL TISSUE WITH OVARIAN THECAL METAPLASIA A: The he...
Images
Images
Figure 4-24
Published: 01 December 2024
pigmentation, and endocrine overactivity (Carney complex). There was a complex history of a retrogastric malignant melanotic nerve sheath tumor (formerly “melanotic schwannoma”), fibrolamellar hepatoma, hyperpigmentation of the inner canthus of both eyes, and most recently, an ovarian serous cystadenoma More about this image found in PRIMARY PIGMENTED NODULAR ADRENOCORTICAL DISEASE A large pigmented macrono...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-02
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... tissue ( 22 ). These neoplasms can pose severe diagnostic challenges. Although the developmentally predictable distribution of ectopic adrenal tissue helps explain where some of these arise, some cases defy ready embryologic explanation. ACCESSORY ADRENAL CORTICAL TISSUE WITH OVARIAN THECAL METAPLASIA...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-01
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... of both sexes. Although usually not clinically significant, they may be associated with autoimmune inflammation in other organs ( 52 ). Lymphocytic adrenal medullitis has been reported in patients with rabies and in occasional patients with paroxysmal hypertensive episodes. Ovarian Thecal Metaplasia...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-12
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... cortex. Adrenal ganglioneuromas containing Leydig cells with pathognomonic Reinke crystalloids ( fig. 12-18 ) have been reported in two virilized women ( 54 , 55 ), one of whom also had ovarian stromal hyperthecosis and hilus cell hyperplasia ( 55 ). Although these cases are reported as virilizing...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-07
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... peripheral nerve sheet tumors, benign neural tumors BRCA2 BRCA2 Carcinoma <1% Breast, ovarian, prostate, pancreatic, gastric cancers a See chapter 2 . b MEN1 = multiple endocrine neoplasia 1; HLCC = hereditary leiomyomatosis and renal cell carcinoma; FAP = familial...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-04
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... pigmentation, and endocrine overactivity (Carney complex). There was a complex history of a retrogastric malignant melanotic nerve sheath tumor (formerly “melanotic schwannoma”), fibrolamellar hepatoma, hyperpigmentation of the inner canthus of both eyes, and most recently, an ovarian serous cystadenoma...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-06
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
...   O , Ezzat   S . Malignant ovarian steroid cell tumor causing severe hyperandrogenism: case report and review of the literature . AACE Clinical Case Rep . 2017 ; 3 : e269 - 74 . 208. Villelli   NW , Jayanti   MK , Zynger   DL . Use and usefulness of adrenal core biopsies...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-02
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
..., therapeutic in the sense that the only goal is to remove all residual, untreated disease. A chemotherapy response score is assigned on evaluation of the omentum in such cases. There are now many clinical trials available to patients with ovarian cancer. There are great hopes for lengthening the duration...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-08
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
...Mucinous ovarian tumors constitute approximately 15 percent of all ovarian tumors. They definitionally have gastrointestinal-type epithelium, as determined either by routine morphology or immunohistochemistry. Tumors with a mullerian-type epithelium are discussed in chapter 10 . Mucinous ovarian...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-12
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... . Breast implant-associated anaplastic large-cell lymphoma: current understanding and recommendations for management . Plast Surg (Oakv)   2020 ; 28 : 117 - 26 . 20. Nonaka   D , Chiriboga   L , Soslow   RA . Expression of pax8 as a useful marker in distinguishing ovarian carcinomas from...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-08
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
...Table 8-1 FAMILIAL SYNDROMES WITH ELEVATED BREAST CANCER RISK a Disease Phenotype Gene Protein Function Pathologic Features Risk of Other Cancers in Families Familial breast ovarian cancer 1 BRCA1 DNA repair Grade 3, IBC NST b ER, PR, HER2...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-14
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... dilatation, and squamous differentiation, and for higher-grade breast tumors, morphologic differences with the primary carcinoma. When present, the myoepithelial cell layer is also a key differentiator. Potentially more problematic, and not that rare an occurrence, is the presentation of serous ovarian...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-15
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... WITH SIGNIFICANT TREATMENT CONSEQUENCES Mimic Features of Distinction Metastatic serous tubo-ovarian carcinoma Papillary architecture Psammomatous calcifications PAX8 and WT1 positive Metastatic malignant melanoma Epithelioid tumors with necrosis difficult to distinguish morphologically...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch49
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
..., the lesions bear more resemblance to ovarian desmoid tumors in adults. While some have advocated the use of a grading system, as in immature teratoma of the ovary, all cardiac teratomas are essentially benign grade I lesions ( 2 , 37 ). The histologic features show more immature features in infants and more...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch42
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... (sheet-like) calcification of the falx Minor Diagnostic Criteria  Cardiac or ovarian fibroma  Lymphomesenteric or pleural cysts  Childhood medulloblastoma  Cleft lip/palate  Macrocephaly  Bifid ribs or extra ribs  Polydactyly  Ocular anomalies (e.g., cataract, pigmentary...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch45
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... fibroelastosis, ovarian cysts, midline defects of the central nervous system, malformations of the eyes, and oncocytic changes in glands ( 24 , 28 , 38 – 42 ). ...