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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-11
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... osteosarcoma, and mesenchymal chondrosarcoma. Patient age, tumor location, and additional clinical information usually narrow this differential diagnosis and a well-chosen panel of immunohistochemical markers almost always results in complete resolution of differential diagnostic uncertainty. NBL and GNBL show...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-02
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... cells admixed with the myelolipoma ( fig. 2-17 ). Adrenal adenomas or carcinomas have been reported but are rare ( 47 ). Several extra-adrenal seemingly unrelated neoplasms have been reported such as osteosarcoma, Ewing sarcoma, astrocytoma ( 49 ), and hepatocellular...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-07
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
..., early onset of tumors, and a wide variety of histologies. Core Li-Fraumeni cancers include: soft tissue sarcomas, osteosarcomas, adrenal cortical carcinoma, central nervous system tumors, and breast cancer in patients under the age of 31 years ( 72 ). Family history of cancer is often mute, and germline...
Images
Published: 01 January 2024
EXTRASKELETAL OSTEOSARCOMA Figure 12-1 EXTRASKELETAL OSTEOSARCOMA A: This intermediate-power image depicts a malignant breast neoplasm composed of highly atypical spindle cells and numerous osteoclastic giant cells. No definitive epithelial component could be identified either with hematoxylin an... More about this image found in EXTRASKELETAL OSTEOSARCOMA A: This intermediate-power image depicts a mali...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-12
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... to the development of breast sarcomas ( 1 ). In addition to angiosarcoma, other types of sarcoma arising in the breast occur secondary to radiation therapy, including fibrosarcoma, leiomyosarcoma, and extraskeletal osteosarcoma ( 2 , 3 ). Clinical Features. Patients usually present with a hard, mobile, rapidly...
Images
Published: 15 November 2023
CARDIAC UNDIFFERENTIATED PLEOMORPHIC SARCOMA Figure 53-12 CARDIAC UNDIFFERENTIATED PLEOMORPHIC SARCOMA Left: Inflammation and cellular pleomorphism are seen in this example with scattered tumor giant cells. Right: Bone formation is focal and not indicative of osteosarcoma. More about this image found in CARDIAC UNDIFFERENTIATED PLEOMORPHIC SARCOMA Left: Inflammation and cellul...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-05
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... epithelial elements. B: Another low power field without epithelial elements. Note also the heterogeneity in stromal cellularity. The presence of malignant heterologous elements, such as osteosarcoma, chondrosarcoma, or rhabdomyosarcoma, automatically defines a tumor as malignant, but is not a prerequisite...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-11
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... , Tan PH , Shaaban A , et al . Do primary mammary osteosarcoma and chondrosarcoma exist? A review of a large multi-institutional series of malignant matrix-producing breast tumours . Breast 2013 ; 22 : 13 - 8 . 45. Baker GM , Schnitt SJ . Vascular lesions of the breast...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch52
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... from soft-tissue sarcomas . J Clin Oncol 1986 ; 4 : 1662 - 9 . 47. Platonov MA , Turner AR , Mullen JC , Noga M , Welsh RC . Tumour on the tricuspid valve: metastatic osteosarcoma and the heart . Can J Cardiol 2005 ; 21 : 63 - 7 . 48. Jani JC...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch53
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... with scattered tumor giant cells. Right: Bone formation is focal and not indicative of osteosarcoma. CARDIAC UNDIFFERENTIATED PLEOMORPHIC SARCOMA Figure 53-1 CARDIAC UNDIFFERENTIATED PLEOMORPHIC SARCOMA Left: Computerized tomographic (CT) reconstruction shows a low-density mass invading the left atrium...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch55
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... 1996 ; 167 : 657 - 9 . 41. Tsunezuka Y , Oda M , Takahashi M , Minato H , Watanabe G . Primary chondromatous osteosarcoma of the pulmonary artery . Ann Thorac Surg 2004 ; 77 : 331 - 4 . 42. Maruo A , Okita Y , Okada K , Yamashita T...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-14
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... serous carcinoma, but other high-grade tumor types can be seen. The sarcomatous component is often nonspecific, but sometimes specific lines of differentiation are identified, such as rhabdomyosarcoma, chondrosarcoma, or osteosarcoma. In metastases, only one component may be present. Immunohistochemical...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 14
Published: 01 February 2023
10.55418/9781933477268-4
ISBN-10: 1-933477-26-1
ISBN: 978-1-933477-26-8
... differentiation (chondrosarcoma, osteosarcoma, liposarcoma, rhabdomyosarcoma). This assessment often requires examination of resection material as the typical morphology may not be visualized in a biopsy. The rarity of this lesion precludes assessment of its origin, although it is presumed that it can arise from...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 14
Published: 01 February 2023
10.55418/9781933477268-3
ISBN-10: 1-933477-26-1
ISBN: 978-1-933477-26-8
... cytologic atypia or heterologous (chondrosarcoma, rhabdomyosarcoma, or osteosarcoma) differentiation; in this case, the term malignant mixed mesonephric tumor or mesonephric carcinosarcoma may be applied ( 172 , 173 ). Ancillary Studies. M-AC is positive for CK7, PAX8, and vimentin...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 14
Published: 01 February 2023
10.55418/9781933477268-5
ISBN-10: 1-933477-26-1
ISBN: 978-1-933477-26-8
... and reverse transcriptase-polymerase chain reaction . Int J Gynecol Pathol 2000 ; 19 : 103 – 9 . 492. Lee AF , Hayes MM , Lebrun D , et al FLI-1 distinguishes Ewing sarcoma from small cell osteosarcoma and mesenchymal chondrosarcoma . Appl Immunohistochem Mol Morphol 2011 ; 19...
Images
in Miscellaneous Primary Testicular, Adnexal, and Spermatic Cord Tumors
> Tumors and Tumor-Like Lesions of the Testis and Adjacent Tissues
Published: 01 August 2022
OSTEOSARCOMA OF TESTIS Figure 8-134 OSTEOSARCOMA OF TESTIS Malignant-appearing spindle cells proliferate between trabeculae of neoplastic bone. Occasional osteoclasts are also seen. More about this image found in OSTEOSARCOMA OF TESTIS Malignant-appearing spindle cells proliferate betwe...
Images
in Germ Cell Neoplasia in Situ and Tumors Derived from Germ Cell Neoplasia in Situ
> Tumors and Tumor-Like Lesions of the Testis and Adjacent Tissues
Published: 01 August 2022
POSTCHEMOTHERAPY SARCOMATOID YOLK SAC TUMOR Figure 4-244 POSTCHEMOTHERAPY SARCOMATOID YOLK SAC TUMOR Extensive basement membrane deposits simulate the features of osteosarcoma. More about this image found in POSTCHEMOTHERAPY SARCOMATOID YOLK SAC TUMOR Extensive basement membrane de...
Images
Published: 01 June 2022
SARCOMATOID MESOTHELIOMA WITH HETEROLOGOUS ELEMENTS Figure 3-61 SARCOMATOID MESOTHELIOMA WITH HETEROLOGOUS ELEMENTS A: A focus of osteosarcoma-like tumor is present. B: There is a focus of osteoid-like matrix. C: More mature bone formation is present. More about this image found in SARCOMATOID MESOTHELIOMA WITH HETEROLOGOUS ELEMENTS A: A focus of osteosar...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
10.55418/9781933477220-08
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
..., fibrous stroma, or more commonly, high-grade, having the morphology of a undifferentiated pleomorphic sarcoma, myxofibrosarcoma, fibrosarcoma, leiomyosarcoma, or osteosarcoma, either in isolation or in combination with other high-grade components ( 390 , 391 ). DEDIFFERENTIATED LIPOSARCOMA Figure 8-102...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
10.55418/9781933477220-04
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
..., corresponding to basement membrane matrix, between small clusters of tumor cells, thereby resembling osteosarcoma ( fig. 4-244 ). A similar case that occurred in a young woman after radiation and chemotherapy for ovarian yolk sac tumor was originally described by Damjanov et al. ( 692 ) as “parietal yolk sac...
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