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osteosarcoma

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EXTRASKELETAL <span class="search-highlight">OSTEOSARCOMA</span>  A: This intermediate-power image depicts a mali...
Published: 01 January 2024
EXTRASKELETAL OSTEOSARCOMA Figure 12-1 EXTRASKELETAL OSTEOSARCOMA A: This intermediate-power image depicts a malignant breast neoplasm composed of highly atypical spindle cells and numerous osteoclastic giant cells. No definitive epithelial component could be identified either with hematoxylin an... More about this image found in EXTRASKELETAL OSTEOSARCOMA A: This intermediate-power image depicts a mali...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-12
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... to the development of breast sarcomas ( 1 ). In addition to angiosarcoma, other types of sarcoma arising in the breast occur secondary to radiation therapy, including fibrosarcoma, leiomyosarcoma, and extraskeletal osteosarcoma ( 2 , 3 ). Clinical Features. Patients usually present with a hard, mobile, rapidly...
Images
CARDIAC UNDIFFERENTIATED PLEOMORPHIC SARCOMA  Left: Inflammation and cellul...
Published: 15 November 2023
CARDIAC UNDIFFERENTIATED PLEOMORPHIC SARCOMA Figure 53-12 CARDIAC UNDIFFERENTIATED PLEOMORPHIC SARCOMA Left: Inflammation and cellular pleomorphism are seen in this example with scattered tumor giant cells. Right: Bone formation is focal and not indicative of osteosarcoma. More about this image found in CARDIAC UNDIFFERENTIATED PLEOMORPHIC SARCOMA Left: Inflammation and cellul...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-05
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... epithelial elements. B: Another low power field without epithelial elements. Note also the heterogeneity in stromal cellularity. The presence of malignant heterologous elements, such as osteosarcoma, chondrosarcoma, or rhabdomyosarcoma, automatically defines a tumor as malignant, but is not a prerequisite...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-11
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... , Tan   PH , Shaaban   A , et al . Do primary mammary osteosarcoma and chondrosarcoma exist? A review of a large multi-institutional series of malignant matrix-producing breast tumours . Breast   2013 ; 22 : 13 - 8 . 45. Baker   GM , Schnitt   SJ . Vascular lesions of the breast...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch52
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... from soft-tissue sarcomas . J Clin Oncol   1986 ; 4 : 1662 - 9 . 47. Platonov   MA , Turner   AR , Mullen   JC , Noga   M , Welsh   RC . Tumour on the tricuspid valve: metastatic osteosarcoma and the heart . Can J Cardiol   2005 ; 21 : 63 - 7 . 48. Jani   JC...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch53
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... with scattered tumor giant cells. Right: Bone formation is focal and not indicative of osteosarcoma. CARDIAC UNDIFFERENTIATED PLEOMORPHIC SARCOMA Figure 53-1 CARDIAC UNDIFFERENTIATED PLEOMORPHIC SARCOMA Left: Computerized tomographic (CT) reconstruction shows a low-density mass invading the left atrium...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch55
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
...   1996 ; 167 : 657 - 9 . 41. Tsunezuka   Y , Oda   M , Takahashi   M , Minato   H , Watanabe   G . Primary chondromatous osteosarcoma of the pulmonary artery . Ann Thorac Surg   2004 ; 77 : 331 - 4 . 42. Maruo   A , Okita   Y , Okada   K , Yamashita   T...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-14
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... serous carcinoma, but other high-grade tumor types can be seen. The sarcomatous component is often nonspecific, but sometimes specific lines of differentiation are identified, such as rhabdomyosarcoma, chondrosarcoma, or osteosarcoma. In metastases, only one component may be present. Immunohistochemical...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 14
Published: 01 February 2023
10.55418/9781933477268-4
ISBN-10: 1-933477-26-1
ISBN: 978-1-933477-26-8
... differentiation (chondrosarcoma, osteosarcoma, liposarcoma, rhabdomyosarcoma). This assessment often requires examination of resection material as the typical morphology may not be visualized in a biopsy. The rarity of this lesion precludes assessment of its origin, although it is presumed that it can arise from...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 14
Published: 01 February 2023
10.55418/9781933477268-3
ISBN-10: 1-933477-26-1
ISBN: 978-1-933477-26-8
... cytologic atypia or heterologous (chondrosarcoma, rhabdomyosarcoma, or osteosarcoma) differentiation; in this case, the term malignant mixed mesonephric tumor or mesonephric carcinosarcoma may be applied ( 172 , 173 ). Ancillary Studies. M-AC is positive for CK7, PAX8, and vimentin...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 14
Published: 01 February 2023
10.55418/9781933477268-5
ISBN-10: 1-933477-26-1
ISBN: 978-1-933477-26-8
... and reverse transcriptase-polymerase chain reaction . Int J Gynecol Pathol   2000 ; 19 : 103 – 9 . 492. Lee   AF , Hayes   MM , Lebrun   D , et al   FLI-1 distinguishes Ewing sarcoma from small cell osteosarcoma and mesenchymal chondrosarcoma . Appl Immunohistochem Mol Morphol   2011 ; 19...
Images
<span class="search-highlight">OSTEOSARCOMA</span> OF TESTIS  Malignant-appearing spindle cells proliferate betwe...
Published: 01 August 2022
OSTEOSARCOMA OF TESTIS Figure 8-134 OSTEOSARCOMA OF TESTIS Malignant-appearing spindle cells proliferate between trabeculae of neoplastic bone. Occasional osteoclasts are also seen. More about this image found in OSTEOSARCOMA OF TESTIS Malignant-appearing spindle cells proliferate betwe...
Images
Images
SARCOMATOID MESOTHELIOMA WITH HETEROLOGOUS ELEMENTS  A: A focus of osteosar...
Published: 01 June 2022
SARCOMATOID MESOTHELIOMA WITH HETEROLOGOUS ELEMENTS Figure 3-61 SARCOMATOID MESOTHELIOMA WITH HETEROLOGOUS ELEMENTS A: A focus of osteosarcoma-like tumor is present. B: There is a focus of osteoid-like matrix. C: More mature bone formation is present. More about this image found in SARCOMATOID MESOTHELIOMA WITH HETEROLOGOUS ELEMENTS A: A focus of osteosar...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
10.55418/9781933477220-08
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
..., fibrous stroma, or more commonly, high-grade, having the morphology of a undifferentiated pleomorphic sarcoma, myxofibrosarcoma, fibrosarcoma, leiomyosarcoma, or osteosarcoma, either in isolation or in combination with other high-grade components ( 390 , 391 ). DEDIFFERENTIATED LIPOSARCOMA Figure 8-102...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
10.55418/9781933477220-04
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
..., corresponding to basement membrane matrix, between small clusters of tumor cells, thereby resembling osteosarcoma ( fig. 4-244 ). A similar case that occurred in a young woman after radiation and chemotherapy for ovarian yolk sac tumor was originally described by Damjanov et al. ( 692 ) as “parietal yolk sac...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 11
Published: 01 June 2022
10.55418/9781933477190-5
ISBN-10: 1-933477-19-9
ISBN: 978-1-933477-19-0
... osteosarcoma ( 121 ) and chondrosarcoma ( 122 ) have also been reported but, if there is no evidence of tumor origin from bone ( fig. 5-19C ), specifically, direct spread from rib to involve the pleura, then osteosarcomatous or chondrosarcomatous dedifferentiation of a mesothelioma cannot be excluded...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 11
Published: 01 June 2022
10.55418/9781933477190-3
ISBN-10: 1-933477-19-9
ISBN: 978-1-933477-19-0
... elements, osteosarcoma is most common, followed by a mixture of osteosarcoma and chondrosarcoma, rhabdomyosarcoma only, and chondrosarcoma only ( 175 ). Muscle markers may be required to confirm rhabdomyosarcomatous areas. When there is a diffuse pleural tumor with heterologous elements, even...
Images
CLEAR CELL SARCOMA OF THE KIDNEY  The hyaline sclerotic pattern simulates o...
Published: 01 November 2021
CLEAR CELL SARCOMA OF THE KIDNEY Figure 1-89 CLEAR CELL SARCOMA OF THE KIDNEY The hyaline sclerotic pattern simulates osteoid, and can result in a misdiagnosis of osteosarcoma. More about this image found in CLEAR CELL SARCOMA OF THE KIDNEY The hyaline sclerotic pattern simulates o...