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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 8
Published: 01 October 2021
10.55418/9781933477138-10
ISBN-10: 1-933477-13-X
ISBN: 978-1-933477-13-8
...Table 10-1 MAIN DISTINGUISHING FEATURES OF OSTEOFIBROUS DYSPLASIA AND ADAMANTINOMA Osteofibrous Dysplasia (OFD) OFD-Like Adamantinoma Classic Adamantinoma Dedifferentiated Adamantinoma Age Mean 13.5 years (range, 1-49 years) Mean 13.4 years (range, 6-28 years) Mean 38 years...
Images
Figure 10-11
Published: 01 October 2021
OSTEOFIBROUS DYSPLASIA LIKE-ADAMANTINOMA Figure 10-11 OSTEOFIBROUS DYSPLASIA LIKE-ADAMANTINOMA Left: Based on current criteria, the distinction of osteofibrous dysplasia from osteofibrous dysplasia-like adamantinoma is the presence of epithelial nests (clusters of three or more cells). Right More about this image found in OSTEOFIBROUS DYSPLASIA LIKE-ADAMANTINOMA Left: Based on current criteria, ...
Images
Figure 10-6
Published: 01 October 2021
OSTEOFIBROUS DYSPLASIA Figure 10-6 OSTEOFIBROUS DYSPLASIA The keratin-positive cells in osteofibrous dysplasia are solitary and spindled. When keratin-positive cells are more round and form small clusters, a diagnosis of osteofibrous dysplasia-like adamantinoma is warranted. More about this image found in OSTEOFIBROUS DYSPLASIA The keratin-positive cells in osteofibrous dysplasi...
Images
Figure 10-3
Published: 01 October 2021
OSTEOFIBROUS DYSPLASIA Figure 10-3 OSTEOFIBROUS DYSPLASIA Resection specimen of osteofibrous dysplasia of the tibia, showing the cortical thickening. Solid white-yellow tissue is seen with a soft or gritty texture, blending into the surrounding cortical bone. More about this image found in OSTEOFIBROUS DYSPLASIA Resection specimen of osteofibrous dysplasia of the...
Images
Figure 10-10
Published: 01 October 2021
OSTEOFIBROUS DYSPLASIA-LIKE ADAMANTINOMA Figure 10-10 OSTEOFIBROUS DYSPLASIA-LIKE ADAMANTINOMA Left: Osteoclast-like giant cells in osteofibrous dysplasia-like adamantinoma are close to the woven bone trabeculae. Right: High-power view shows small nests of epithelial cells. More about this image found in OSTEOFIBROUS DYSPLASIA-LIKE ADAMANTINOMA Left: Osteoclast-like giant cells...
Images
Figure 10-2
Published: 01 October 2021
OSTEOFIBROUS DYSPLASIA Figure 10-2 OSTEOFIBROUS DYSPLASIA A: Lateral radiograph of the leg shows a lytic lesion in the anterior cortex of the distal tibial shaft (arrows), the typical location of osteofibrous dysplasia. B: Magnified view shows multiple lytic cortical lesions. C: Axial More about this image found in OSTEOFIBROUS DYSPLASIA A: Lateral radiograph of the leg shows a lytic lesi...
Images
Figure 10-9
Published: 01 October 2021
OSTEOFIBROUS DYSPLASIA-LIKE ADAMANTINOMA Figure 10-9 OSTEOFIBROUS DYSPLASIA-LIKE ADAMANTINOMA Left: At low power morphology is very similar to that of osteofibrous dysplasia, with irregular woven bone lined by well-defined osteoblasts in a background of fibrous stroma. Distinction should be made More about this image found in OSTEOFIBROUS DYSPLASIA-LIKE ADAMANTINOMA Left: At low power morphology is ...
Images
Figure 10-7
Published: 01 October 2021
OSTEOFIBROUS DYSPLASIA-LIKE ADAMANTINOMA Figure 10-7 OSTEOFIBROUS DYSPLASIA-LIKE ADAMANTINOMA A: Lateral radiograph of the leg in a patient with osteofibrous dysplasia-like adamantinoma shows a lytic lesion in the anterior tibia, which involves the anterior cortex with extension More about this image found in OSTEOFIBROUS DYSPLASIA-LIKE ADAMANTINOMA A: Lateral radiograph of the leg ...
Images
Figure 10-8
Published: 01 October 2021
OSTEOFIBROUS DYSPLASIA-LIKE ADAMANTINOMA Figure 10-8 OSTEOFIBROUS DYSPLASIA-LIKE ADAMANTINOMA The cortex and medullary cavity are involved by tumor. More about this image found in OSTEOFIBROUS DYSPLASIA-LIKE ADAMANTINOMA The cortex and medullary cavity a...
Images
Figure 10-5
Published: 01 October 2021
OSTEOFIBROUS DYSPLASIA Figure 10-5 OSTEOFIBROUS DYSPLASIA Prominent osteoblastic rimming of irregular woven bone trabeculae is characteristically seen in a background of a bland, storiform, fibrous spindle cell proliferation. More about this image found in OSTEOFIBROUS DYSPLASIA Prominent osteoblastic rimming of irregular woven b...
Images
Figure 10-1
Published: 01 October 2021
OSTEOFIBROUS DYSPLASIA Figure 10-1 OSTEOFIBROUS DYSPLASIA A: Lateral radiograph of the leg in a 2-year-old girl demonstrates a well-defined cortical lytic lesion with sclerotic margins in the anterior tibial diaphysis. B: Sagittal fat-suppressed T2-weighted magnetic resonance imaging (MRI More about this image found in OSTEOFIBROUS DYSPLASIA A: Lateral radiograph of the leg in a 2-year-old gi...
Images
Figure 10-4
Published: 01 October 2021
OSTEOFIBROUS DYSPLASIA Figure 10-4 OSTEOFIBROUS DYSPLASIA Left: Woven bone is being formed in an irregular fashion by well-defined osteoblasts. There is a loose fibrous stroma in which the fibrous cells have bland, ovoid to thin and pointed nuclei. Their cytoplasm is pale eosinophilic with ill More about this image found in OSTEOFIBROUS DYSPLASIA Left: Woven bone is being formed in an irregular fa...
Images
Figure 3-9
Published: 01 October 2021
TIBIAL BONE TUMORS Figure 3-9 TIBIAL BONE TUMORS Adamantinoma (left) and osteofibrous dysplasia (right) (arrows). More about this image found in TIBIAL BONE TUMORS Adamantinoma (left) and osteofibrous dysplasia (right) ...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 8
Published: 01 October 2021
10.55418/9781933477138-03
ISBN-10: 1-933477-13-X
ISBN: 978-1-933477-13-8
...) and osteofibrous dysplasia (right) (arrows). FDG POSITRON EMISSION TOMOGRAPHY (PET)/CT Figure 3-6 FDG POSITRON EMISSION TOMOGRAPHY (PET)/CT Axial (A), sagittal (B), and coronal (C) fused FDG-PET/CT images in a patient with a history of osteosarcoma of the thoracic spine (T4), status postresection, demonstrate...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 8
Published: 01 October 2021
10.55418/9781933477138-09
ISBN-10: 1-933477-13-X
ISBN: 978-1-933477-13-8
... by prominent osteoblasts. Osteofibrous dysplasia invariably arises in the anterior cortex of the tibia and fibula rather than the medullary cavity and, unlike fibrous dysplasia, shows prominent osteoblastic rimming of the lesional bone. Also, the spindle cells in osteofibrous dysplasia are focally...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 8
Published: 01 October 2021
10.55418/9781933477138-01
ISBN-10: 1-933477-13-X
ISBN: 978-1-933477-13-8
... Neoplasms of osteoblastic and fibroblastic phenotype: fibro-osseous tumors Neoplasms of epithelial, osteoblastic, and fibroblastic phenotype: osteofibrous dysplasia and adamantinoma Neoplasms of endothelial phenotype: vascular tumors Neoplasms of notochordal phenotype: notochordal cell tumors...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 8
Published: 01 October 2021
10.55418/9781933477138-05
ISBN-10: 1-933477-13-X
ISBN: 978-1-933477-13-8
... osteosarcoma include fibrous dysplasia, osteofibrous dysplasia, and desmoplastic fibroma. Morphology, immunohistochemistry, and molecular genetic studies are useful in distinguishing these entities. Low-grade central osteosarcoma has a permeative growth pattern that is absent in the other fibrous and fibro...