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osteofibrous

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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 8
Published: 01 October 2021
10.55418/9781933477138-10
ISBN-10: 1-933477-13-X
ISBN: 978-1-933477-13-8
...Osteofibrous dysplasia is considered a benign fibro-osseous intracortical lesion of long bone, while adamantinoma is defined as a malignant biphasic tumor characterized by epithelial cells, embedded in a fairly bland osteofibrous proliferation. Based on overlapping clinical...
Images
<span class="search-highlight">OSTEOFIBROUS</span> DYSPLASIA LIKE-ADAMANTINOMA  Left: Based on current criteria, ...
Published: 01 October 2021
OSTEOFIBROUS DYSPLASIA LIKE-ADAMANTINOMA Figure 10-11 OSTEOFIBROUS DYSPLASIA LIKE-ADAMANTINOMA Left: Based on current criteria, the distinction of osteofibrous dysplasia from osteofibrous dysplasia-like adamantinoma is the presence of epithelial nests (clusters of three or more cells). Right: Wh... More about this image found in OSTEOFIBROUS DYSPLASIA LIKE-ADAMANTINOMA Left: Based on current criteria, ...
Images
<span class="search-highlight">OSTEOFIBROUS</span> DYSPLASIA  The keratin-positive cells in <span class="search-highlight">osteofibrous</span> dysplasi...
Published: 01 October 2021
OSTEOFIBROUS DYSPLASIA Figure 10-6 OSTEOFIBROUS DYSPLASIA The keratin-positive cells in osteofibrous dysplasia are solitary and spindled. When keratin-positive cells are more round and form small clusters, a diagnosis of osteofibrous dysplasia-like adamantinoma is warranted. More about this image found in OSTEOFIBROUS DYSPLASIA The keratin-positive cells in osteofibrous dysplasi...
Images
<span class="search-highlight">OSTEOFIBROUS</span> DYSPLASIA  Resection specimen of <span class="search-highlight">osteofibrous</span> dysplasia of the...
Published: 01 October 2021
OSTEOFIBROUS DYSPLASIA Figure 10-3 OSTEOFIBROUS DYSPLASIA Resection specimen of osteofibrous dysplasia of the tibia, showing the cortical thickening. Solid white-yellow tissue is seen with a soft or gritty texture, blending into the surrounding cortical bone. More about this image found in OSTEOFIBROUS DYSPLASIA Resection specimen of osteofibrous dysplasia of the...
Images
<span class="search-highlight">OSTEOFIBROUS</span> DYSPLASIA-LIKE ADAMANTINOMA  Left: Osteoclast-like giant cells...
Published: 01 October 2021
OSTEOFIBROUS DYSPLASIA-LIKE ADAMANTINOMA Figure 10-10 OSTEOFIBROUS DYSPLASIA-LIKE ADAMANTINOMA Left: Osteoclast-like giant cells in osteofibrous dysplasia-like adamantinoma are close to the woven bone trabeculae. Right: High-power view shows small nests of epithelial cells. More about this image found in OSTEOFIBROUS DYSPLASIA-LIKE ADAMANTINOMA Left: Osteoclast-like giant cells...
Images
<span class="search-highlight">OSTEOFIBROUS</span> DYSPLASIA  A: Lateral radiograph of the leg shows a lytic lesi...
Published: 01 October 2021
OSTEOFIBROUS DYSPLASIA Figure 10-2 OSTEOFIBROUS DYSPLASIA A: Lateral radiograph of the leg shows a lytic lesion in the anterior cortex of the distal tibial shaft (arrows), the typical location of osteofibrous dysplasia. B: Magnified view shows multiple lytic cortical lesions. C: Axial computeri... More about this image found in OSTEOFIBROUS DYSPLASIA A: Lateral radiograph of the leg shows a lytic lesi...
Images
<span class="search-highlight">OSTEOFIBROUS</span> DYSPLASIA-LIKE ADAMANTINOMA  Left: At low power morphology is ...
Published: 01 October 2021
OSTEOFIBROUS DYSPLASIA-LIKE ADAMANTINOMA Figure 10-9 OSTEOFIBROUS DYSPLASIA-LIKE ADAMANTINOMA Left: At low power morphology is very similar to that of osteofibrous dysplasia, with irregular woven bone lined by well-defined osteoblasts in a background of fibrous stroma. Distinction should be made ... More about this image found in OSTEOFIBROUS DYSPLASIA-LIKE ADAMANTINOMA Left: At low power morphology is ...
Images
<span class="search-highlight">OSTEOFIBROUS</span> DYSPLASIA-LIKE ADAMANTINOMA  A: Lateral radiograph of the leg ...
Published: 01 October 2021
OSTEOFIBROUS DYSPLASIA-LIKE ADAMANTINOMA Figure 10-7 OSTEOFIBROUS DYSPLASIA-LIKE ADAMANTINOMA A: Lateral radiograph of the leg in a patient with osteofibrous dysplasia-like adamantinoma shows a lytic lesion in the anterior tibia, which involves the anterior cortex with extension into the medullar... More about this image found in OSTEOFIBROUS DYSPLASIA-LIKE ADAMANTINOMA A: Lateral radiograph of the leg ...
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<span class="search-highlight">OSTEOFIBROUS</span> DYSPLASIA-LIKE ADAMANTINOMA  The cortex and medullary cavity a...
Published: 01 October 2021
OSTEOFIBROUS DYSPLASIA-LIKE ADAMANTINOMA Figure 10-8 OSTEOFIBROUS DYSPLASIA-LIKE ADAMANTINOMA The cortex and medullary cavity are involved by tumor. More about this image found in OSTEOFIBROUS DYSPLASIA-LIKE ADAMANTINOMA The cortex and medullary cavity a...
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<span class="search-highlight">OSTEOFIBROUS</span> DYSPLASIA  Prominent osteoblastic rimming of irregular woven b...
Published: 01 October 2021
OSTEOFIBROUS DYSPLASIA Figure 10-5 OSTEOFIBROUS DYSPLASIA Prominent osteoblastic rimming of irregular woven bone trabeculae is characteristically seen in a background of a bland, storiform, fibrous spindle cell proliferation. More about this image found in OSTEOFIBROUS DYSPLASIA Prominent osteoblastic rimming of irregular woven b...
Images
<span class="search-highlight">OSTEOFIBROUS</span> DYSPLASIA  A: Lateral radiograph of the leg in a 2-year-old gi...
Published: 01 October 2021
OSTEOFIBROUS DYSPLASIA Figure 10-1 OSTEOFIBROUS DYSPLASIA A: Lateral radiograph of the leg in a 2-year-old girl demonstrates a well-defined cortical lytic lesion with sclerotic margins in the anterior tibial diaphysis. B: Sagittal fat-suppressed T2-weighted magnetic resonance imaging (MRI) shows... More about this image found in OSTEOFIBROUS DYSPLASIA A: Lateral radiograph of the leg in a 2-year-old gi...
Images
<span class="search-highlight">OSTEOFIBROUS</span> DYSPLASIA  Left: Woven bone is being formed in an irregular fa...
Published: 01 October 2021
OSTEOFIBROUS DYSPLASIA Figure 10-4 OSTEOFIBROUS DYSPLASIA Left: Woven bone is being formed in an irregular fashion by well-defined osteoblasts. There is a loose fibrous stroma in which the fibrous cells have bland, ovoid to thin and pointed nuclei. Their cytoplasm is pale eosinophilic with ill-de... More about this image found in OSTEOFIBROUS DYSPLASIA Left: Woven bone is being formed in an irregular fa...
Images
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 8
Published: 01 October 2021
10.55418/9781933477138-03
ISBN-10: 1-933477-13-X
ISBN: 978-1-933477-13-8
... sarcoma and lymphoma tend to follow the distribution of red bone marrow and involve the diaphyses of long bones or flat bones of the pelvis. Some bone tumors have a predilection for a particular bone and location, such as adamantinoma and osteofibrous dysplasia, which typically involve the anterior cortex...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 8
Published: 01 October 2021
10.55418/9781933477138-09
ISBN-10: 1-933477-13-X
ISBN: 978-1-933477-13-8
... dysplasia from osteofibrous dysplasia. The proliferation rate estimated from the Ki-67 nuclear labeling index is usually less than 5 percent; this rate overlaps with that of low-grade central osteosarcoma ( fig. 9-23 ). FIBROUS DYSPLASIA Figure 9-23 FIBROUS DYSPLASIA Immunohistochemical stain for Ki-67...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 8
Published: 01 October 2021
10.55418/9781933477138-01
ISBN-10: 1-933477-13-X
ISBN: 978-1-933477-13-8
... of fibroblastic phenotype: fibrous and fibrohistiocytic tumors Neoplasms of osteoblastic and fibroblastic phenotype: fibro-osseous tumors Neoplasms of epithelial, osteoblastic, and fibroblastic phenotype: osteofibrous dysplasia and adamantinoma Neoplasms of endothelial phenotype: vascular tumors...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 8
Published: 01 October 2021
10.55418/9781933477138-05
ISBN-10: 1-933477-13-X
ISBN: 978-1-933477-13-8
... that can be confused with low-grade central osteosarcoma include fibrous dysplasia, osteofibrous dysplasia, and desmoplastic fibroma. Morphology, immunohistochemistry, and molecular genetic studies are useful in distinguishing these entities. Low-grade central osteosarcoma has a permeative growth pattern...