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COMPLEX SCLEROSING LESION  A: In this lesion, there is less <span class="search-highlight">organization</span> of...
Published: 01 January 2024
COMPLEX SCLEROSING LESION Figure 6-28 COMPLEX SCLEROSING LESION A: In this lesion, there is less organization of the epithelial elements. Stromal sclerosis distorts ducts and glands. B: High-power view of an area of sclerosis and elastosis with entrapped glands. Usual ductal hyperplasia is prese... More about this image found in COMPLEX SCLEROSING LESION A: In this lesion, there is less organization of...
Images
SPITZ NEVUS MISDIAGNOSED AS NEVOID MELANOMA  A: Silhouette of a raised nodu...
Published: 01 February 2024
SPITZ NEVUS MISDIAGNOSED AS NEVOID MELANOMA Figure 17-12 SPITZ NEVUS MISDIAGNOSED AS NEVOID MELANOMA A: Silhouette of a raised nodule with consumption of the epidermis. B: The tumor cells are diffusely positive for NTRK1; no cytogenetic aberration rearrangement was found. C: There is some, albe... More about this image found in SPITZ NEVUS MISDIAGNOSED AS NEVOID MELANOMA A: Silhouette of a raised nodu...
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NONBACTERIAL THROMBOTIC ENDOCARDITIS: <span class="search-highlight">ORGANIZED</span>  <span class="search-highlight">Organized</span> sites of nonbact...
Published: 15 November 2023
NONBACTERIAL THROMBOTIC ENDOCARDITIS: ORGANIZED Figure 11-4 NONBACTERIAL THROMBOTIC ENDOCARDITIS: ORGANIZED Organized sites of nonbacterial thrombotic endocarditis manifest as patchy valve thickening (yellow arrows) grossly. More about this image found in NONBACTERIAL THROMBOTIC ENDOCARDITIS: ORGANIZED Organized sites of nonbact...
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LIBMAN-SACKS ENDOCARDITIS: <span class="search-highlight">ORGANIZED</span>  An <span class="search-highlight">organized</span> vegetation contains chro...
Published: 15 November 2023
LIBMAN-SACKS ENDOCARDITIS: ORGANIZED Figure 11-11 LIBMAN-SACKS ENDOCARDITIS: ORGANIZED An organized vegetation contains chronic inflammation and neovascularization. More about this image found in LIBMAN-SACKS ENDOCARDITIS: ORGANIZED An organized vegetation contains chro...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-17
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... Health Organization (WHO) classification of skin tumors distinguishes papillomatous from maturing variants of nevoid melanoma ( 12 , 13 ). The papillomatous variant of nevoid melanoma (also termed verrucous pseudonevoid melanoma) displays exophytic papillary projections, in which...
Images
CYSTIC NEUTROPHILIC GRANULOMATOUS MASTITIS  A: Scanning magnification of a ...
Published: 01 January 2024
CYSTIC NEUTROPHILIC GRANULOMATOUS MASTITIS Figure 2-5 CYSTIC NEUTROPHILIC GRANULOMATOUS MASTITIS A: Scanning magnification of a breast core needle biopsy showing granulomatous inflammation. B: High power of a granuloma shows the admixed neutrophils. C: Cystic areas surrounded by a cuff of neutrophils. D: Brown and Brenn stain illustrates the presence of Gram-positive rods within a cystic space. The organisms are consistent with Corynebacteria species. More about this image found in CYSTIC NEUTROPHILIC GRANULOMATOUS MASTITIS A: Scanning magnification of a ...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-19
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... (see fig. 19-3 ). MOLECULAR GENETIC FINDINGS Many tumors reported as spitzoid melanomas are not “true” Spitz melanomas by World Health Organization (WHO) criteria ( 3 , 4 ). Melanomas that show microscopic features overlapping with Spitz tumors, but have driver mutations such as BRAF, NRAS...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-23
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... and there is currently no clinical action dependent on it. However, since current reporting guidelines by several national organizations in the United States count TMR as a core value, we also list it here as core parameter to facilitate compliance with contemporary quality metrics for reporting. Microanatomic Level...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-04
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
..., with a brownish rim and erythematous center. (Courtesy of Dr. M. Marchetti, New York, NY) MICROSCOPIC FINDINGS Dysplastic nevi may be junctional or compound; most are compound nevi ( figs. 4-3 – 4-11 ). According to the 2018 World Health Organization (WHO) classification of skin tumors ( 7 ), there are three...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-10
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... lesions, one melanocyte population may display more genetic or genomic aberrations than the other, suggesting tumor progression. According to the most recent World Health Organization (WHO) classification of skin tumors, the term melanocytoma may be used for the latter scenario. CLINICAL FEATURES...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-03
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... of “dysplastic.” According to the recent World Health Organization (WHO) classification of melanocytic tumors, the term dysplastic nevus should be restricted to melanocytic nevi larger than 4 mm in diameter that display more pronounced architectural disorder and atypia ( 30 ). ACQUIRED MELANOCYTIC NEVI...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-07
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... to the most recent World Health Organization (WHO) classification of skin tumors, if genetic/genomic evidence is available and substantiates an intermediate molecular status of a Spitz neoplasm, it is best classified as Spitz melanocytoma ( 12 ). Thus, AST is the preferred term to convey diagnostic...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-08
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... dispersed in a fibrous stroma, typically at the peripheral cellular areas of the fibrous septa separating cellular nodules. The latter are characterized by the presence of round, oval, elongated, or fusiform melanocytes organized in nests or compact bundles or lobules. The presence of well-defined rounded...
Images
NONBACTERIAL THROMBOTIC ENDOCARDITIS: <span class="search-highlight">ORGANIZATION</span>  Fibroblasts and histioc...
Published: 15 November 2023
NONBACTERIAL THROMBOTIC ENDOCARDITIS: ORGANIZATION Figure 11-7 NONBACTERIAL THROMBOTIC ENDOCARDITIS: ORGANIZATION Fibroblasts and histiocytes move into the thrombus and begin to organize it. More about this image found in NONBACTERIAL THROMBOTIC ENDOCARDITIS: ORGANIZATION Fibroblasts and histioc...
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DILATED CARDIOMYOPATHY: VACUOLAR DEGENERATION  Loss of sarcomeres and <span class="search-highlight">organ</span>...
Published: 15 November 2023
DILATED CARDIOMYOPATHY: VACUOLAR DEGENERATION Figure 14-12 DILATED CARDIOMYOPATHY: VACUOLAR DEGENERATION Loss of sarcomeres and organelle swelling impart a vacuolated appearance to the myocytes. More about this image found in DILATED CARDIOMYOPATHY: VACUOLAR DEGENERATION Loss of sarcomeres and organ...
Images
EOSINOPHILIC ENDOMYOCARDIAL DISEASE: TYPE 1  <span class="search-highlight">Organized</span> apical mural thrombu...
Published: 15 November 2023
EOSINOPHILIC ENDOMYOCARDIAL DISEASE: TYPE 1 Figure 16-5 EOSINOPHILIC ENDOMYOCARDIAL DISEASE: TYPE 1 Organized apical mural thrombus (yellow arrow) is seen within the right ventricle. More about this image found in EOSINOPHILIC ENDOMYOCARDIAL DISEASE: TYPE 1 Organized apical mural thrombu...
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EOSINOPHILIC ENDOMYOCARDIAL DISEASE: TYPE 2  <span class="search-highlight">Organized</span> mural thrombi (yello...
Published: 15 November 2023
EOSINOPHILIC ENDOMYOCARDIAL DISEASE: TYPE 2 Figure 16-6 EOSINOPHILIC ENDOMYOCARDIAL DISEASE: TYPE 2 Organized mural thrombi (yellow arrows) are seen at the mid-ventricular level, partially obliterating the right ventricular cavity and involving the left-sided papillary muscles. More about this image found in EOSINOPHILIC ENDOMYOCARDIAL DISEASE: TYPE 2 Organized mural thrombi (yello...
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IDIOPATHIC PERICARDITIS  Histologically, there is <span class="search-highlight">organizing</span> fibrinous peri...
Published: 15 November 2023
IDIOPATHIC PERICARDITIS Figure 27-8 IDIOPATHIC PERICARDITIS Histologically, there is organizing fibrinous pericarditis with a chronically inflamed pericardial wall and a fibrinous surface exudate. More about this image found in IDIOPATHIC PERICARDITIS Histologically, there is organizing fibrinous peri...
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FIBRINOUS PERICARDITIS: PHASES OF <span class="search-highlight">ORGANIZATION</span>  Left: The acute phase of or...
Published: 15 November 2023
FIBRINOUS PERICARDITIS: PHASES OF ORGANIZATION Figure 27-11 FIBRINOUS PERICARDITIS: PHASES OF ORGANIZATION Left: The acute phase of organizing fibrinous pericarditis contains exuberant fibrinous exudate. Right: Chronically, the exudate organizes and becomes fibrotic, with perpendicularly oriente... More about this image found in FIBRINOUS PERICARDITIS: PHASES OF ORGANIZATION Left: The acute phase of or...
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BEHÇET DISEASE  Left: Low-power magnification shows <span class="search-highlight">organizing</span> hematoma wit...
Published: 15 November 2023
BEHÇET DISEASE Figure 30-38 BEHÇET DISEASE Left: Low-power magnification shows organizing hematoma within a bronchus. The artery (Art) can be seen hemorrhaging into the adjacent bronchus (Br). Right: High-power magnification of the artery shows necrosis of the media, which is intact only toward ... More about this image found in BEHÇET DISEASE Left: Low-power magnification shows organizing hematoma wit...