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Images
Published: 01 September 2024
INFECTIVE ENDOCARDITIS Figure 16-2 INFECTIVE ENDOCARDITIS Ocular involvement shows Roth spots on fundoscopic examination. Note the round to flame-shaped retinal hemorrhage with pale center (arrow). (Courtesy of the Centers for Disease Control and Prevention [CDC] Public Health Image Library [PHIL... More about this image found in INFECTIVE ENDOCARDITIS Ocular involvement shows Roth spots on fundoscopic ...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-10
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... extra-adrenal) 2 Neurofibroma and MPNST a Ocular manifestations including Lisch nodules and optic gliomas Café-aulait spots Duodenal neuroendocrine tumor Renal, liver, and epididymal cysts VHL 3p25.5 VHL (von Hippel-Lindau disease) Adrenal and extra-adrenal 1 Clear cell...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-22
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., and includes meningismus and decreased consciousness. CNS candidiasis is associated with significant morbidity (particularly hydrocephalus) and mortality. Ocular infections such as chorioretinitis and endophthalmitis are usually seen with hematogenous dissemination. Infection of bone...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-16
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... presents the salient clinical features and test results associated with infective endocarditis. INFECTIVE ENDOCARDITIS Figure 16-2 INFECTIVE ENDOCARDITIS Ocular involvement shows Roth spots on fundoscopic examination. Note the round to flame-shaped retinal hemorrhage with pale center (arrow). (Courtesy...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-25
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... symptomatic infection in immunocompetent individuals usually presents with infectious mononucleosis-like features, including fever and cervical lymphadenopathy, which may be accompanied by asthenia and myalgia ( 6 ). Ocular involvement, mainly chorioretinitis, can occur during acute infection ( fig. 25-2...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-20
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... presentation and may precede CNS disease ( fig. 20-2 ). Dissemination to the urinary tract, especially the prostate gland, may be asymptomatic or associated with symptoms of prostatitis and obstruction ( 9 ). Eye manifestations include ocular muscle palsy (due to cranial nerve involvement), papilledema...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-18
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... meningitis, ocular or auditory involvement, memory loss, mental confusion, hemiplegia, aphasia, stroke, and tabes dorsalis Latent syphilis Divided into early and late forms, depending on the timing after primary infection Asymptomatic and can only be diagnosed using serology In 1/4 of patients...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-27
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., and a nonproductive cough. Less frequently, abdominal pain, vomiting, weight loss, hyperesthesia, conjunctival hyperemia, and photophobia are seen. Physical examination typically reveals mild jaundice, hepatosplenomegaly, pharyngeal erythema, and a variety of ocular findings (including retinal hemorrhages). Splenic...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-04
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... ( 36 ). AdV ocular infection can present as pharyngoconjunctival fever (common in children and mostly sporadic), epidemic keratoconjunctivitis (a highly contagious and frequently severe form of eye disease), or nonspecific conjunctivitis ( 37 ). GI infections usually present with watery diarrhea...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-26
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... and is often associated with H. pylori gastritis ( 26 ). Uncommonly, there may be colonic involvement or extraintestinal manifestations (often in immunocompromised patients) such as pancreatobiliary disease, a skin rash (including urticaria), and joint and ocular inflammation ( 27 ). G...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-14
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... associated with more severe clinical features ( 35 ). Symptomatic infection initially presents with fever, headache (most notably retroorbital), anorexia, myalgia, and arthralgia. As the disease progresses, ocular manifestations, including photophobia, conjunctival purulent exudate and suffusion...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-24
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., with osteoarticular (most frequent), pulmonary (often cavitating), ocular, oropharyngeal, or central nervous system (CNS)/meningeal involvement. Primary pulmonary sporotrichosis and disseminated systemic sporotrichosis occur in immunocompromised individuals, including alcoholics; those with underlying pulmonary...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-03
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., and myelitis Mostly in adults and older children During pregnancy, can cause stillbirth and Zika congenital syndrome (microcephaly, limb contractures, ocular and hearing abnormalities) WNV 80% 3-14 days Headache, body aches, fatigue, nausea, vomiting, fever Rarely rash and lymphadenopathy Meningitis...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-21
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... and includes multiple sites, especially the skin; oral ( fig. 21-16 ), pharyngeal, and laryngeal mucosa; and adrenal gland and liver. Facial lesions have a predilection for the mouth and ocular mucosa. The lesions vary from plaques to nodules that ulcerate, have verrucous borders, and result in extensive...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-12
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... inhalation. During such a paroxysm, the patients may become cyanotic and there may be ocular proptosis and lacrimation, tongue protrusion, production of thick mucus, and vomiting ( fig. 12-17 ). There is no fever, but there may be fatigue and an inability to sleep. The paroxysms are most striking and severe...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-22
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... cell nevi, but also blue nevi ( fig. 22-8 ). Metastatic melanoma simulating blue nevus has been reported for both cutaneous and ocular melanomas ( 12 , 13 ). The diagnosis of a nevoid melanoma metastasis mainly relies on clinical context (time course and location that fit with metastatic disease...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-01
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... mutation Lentigines ECG abnormality Ocular hypertelorism Pulmonic stenosis Abnormality of genitalia Retarded growth with skeletal abnormalities Deafness LABIAL MELANOTIC MACULES Figure 1-8 LABIAL MELANOTIC MACULES Patient with Peutz-Jeghers syndrome. Hypermelanosis...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-08
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
...-Like Melanoma. On occasion, melanoma metastatic to the skin simulates the clinical and/or histopathologic appearance of a BN ( 41 ). Clinical context and attention to cytologic features are essential for the correct diagnosis. A prior history of cutaneous, mucosal, or ocular melanoma...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-10
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... syndrome, with risk for ocular melanoma, mesothelioma, renal cell carcinoma, and other neoplasms ( Table 10-2 ) ( 11 ). Microscopic features suggestive of a germline mutation include the presence of junctional nests with BAP1 loss and fatty metaplasia of dermal melanocytes. Some BAP1-inactivated nevi show...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-18
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... (cutaneous or ocular) melanoma, as well as pigmented melanotic schwannian neoplasms. Blue Melanoma versus Blue Nevus. Confusion between a melanoma and blue nevus is rare, but may occur, especially in the setting of a cellular blue nevus with atypical features (e.g., nuclear atypia, a few mitotic figures...
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