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Images
Figure 5-17
Published: 01 June 2025
AMELOBLASTOMA IN A LYMPH NODE Figure 5-17 AMELOBLASTOMA IN A LYMPH NODE The tumor is cytologically bland. More about this image found in AMELOBLASTOMA IN A LYMPH NODE The tumor is cytologically bland.
Images
Figure 7-14
Published: 01 June 2025
CLASSIC HODGKIN LYMPHOMA INVOLVING A CERVICAL LYMPH NODE Figure 7-14 CLASSIC HODGKIN LYMPHOMA INVOLVING A CERVICAL LYMPH NODE A,B: Finding binucleated Reed Sternberg cells with their prominent nucleoli as in these two FNA cases suggests the diagnosis of Hodgkin lymphoma. (Papanicolaou stain) More about this image found in CLASSIC HODGKIN LYMPHOMA INVOLVING A CERVICAL LYMPH NODE A,B: Finding binu...
Images
Figure 7-31
Published: 01 June 2025
METASTATIC PAPILLARY THYROID CARCINOMA Figure 7-31 METASTATIC PAPILLARY THYROID CARCINOMA A: The lymph node shows extensive cystic change at low-power magnification. The cystic spaces vary from being empty to filled with densely eosinophilic colloid material or hemorrhage, with scattered More about this image found in METASTATIC PAPILLARY THYROID CARCINOMA A: The lymph node shows extensive c...
Images
Figure 8-27
Published: 01 June 2025
KIMURA DISEASE Figure 8-27 KIMURA DISEASE A: Heavy fibrosis dissects the lymph node into nodules, with areas of central follicle lysis by an eosinophilic infiltrate. B: The center of the lymphoid follicle shows an eosinophilic microabscess. C: The germinal center shows a rich proteinaceous More about this image found in KIMURA DISEASE A: Heavy fibrosis dissects the lymph node into nodules, wit...
Images
Figure 7-1
Published: 01 June 2025
NORMAL ANATOMY OF THE NECK AND NECK LYMPH NODES Figure 7-1 NORMAL ANATOMY OF THE NECK AND NECK LYMPH NODES A: Anatomically and surgically, the neck can be divided into major triangles. The major triangles are the anterior (orange) and posterior (purple), with many subdivisions and boundaries More about this image found in NORMAL ANATOMY OF THE NECK AND NECK LYMPH NODES A: Anatomically and surgic...
Images
Figure 7-12
Published: 01 June 2025
BENIGN ENLARGED CERVICAL LYMPH NODES Figure 7-12 BENIGN ENLARGED CERVICAL LYMPH NODES A–C: Reactive lymphoid hyperplasia shows a polymorphous population of lymphocytes, tingible body macrophages, and lymphohistiocytic aggregates. D: Non-necrotizing granulomatous inflammation can be associated More about this image found in BENIGN ENLARGED CERVICAL LYMPH NODES A–C: Reactive lymphoid hyperplasia sh...
Images
Figure 7-38
Published: 01 June 2025
METASTATIC CARCINOMAS TO SUPRACLAVICULAR LYMPH NODES Figure 7-38 METASTATIC CARCINOMAS TO SUPRACLAVICULAR LYMPH NODES A: Metastatic breast adenocarcinoma was immunohistochemically positive for GATA3 and TRPS1, with crowded atypical glandular cells. B: Metastatic gastric adenocarcinoma More about this image found in METASTATIC CARCINOMAS TO SUPRACLAVICULAR LYMPH NODES A: Metastatic breast ...
Images
Figure 2-32
Published: 01 June 2025
OROPHARYNGEAL SMALL CELL CARCINOMA Figure 2-32 OROPHARYNGEAL SMALL CELL CARCINOMA Cytologic appearance of small cell carcinoma aspirated from a cervical lymph node metastasis. More about this image found in OROPHARYNGEAL SMALL CELL CARCINOMA Cytologic appearance of small cell carc...
Images
Figure 8-39
Published: 01 June 2025
MERKEL CELL CARCINOMA Figure 8-39 MERKEL CELL CARCINOMA This 3.2-cm primary pinna tumor resulted in widely metastatic disease to lymph nodes and other organs. (Courtesy of Dr. J. Lai, Sacramento, CA) More about this image found in MERKEL CELL CARCINOMA This 3.2-cm primary pinna tumor resulted in widely m...
Images
Figure 7-22
Published: 01 June 2025
METASTATIC CILIATED HUMAN PAPILLOMAVIRUS(HPV)-ASSOCIATED SQUAMOUS CELL CARCINOMA Figure 7-22 METASTATIC CILIATED HUMAN PAPILLOMAVIRUS(HPV)-ASSOCIATED SQUAMOUS CELL CARCINOMA Metastasis to a cervical lymph node showing a thin lining epithelium with smooth surface and scattered ciliated cells. More about this image found in METASTATIC CILIATED HUMAN PAPILLOMAVIRUS(HPV)-ASSOCIATED SQUAMOUS CELL CARC...
Images
Images
Figure 2-12
Published: 01 June 2025
HPV-ASSOCIATED OROPHARYNGEAL SQUAMOUS CELL CARCINOMA WITH TUMOR CELL ANAPLASIA AND MULTINUCLEATION Figure 2-12 HPV-ASSOCIATED OROPHARYNGEAL SQUAMOUS CELL CARCINOMA WITH TUMOR CELL ANAPLASIA AND MULTINUCLEATION A: In anaplastic tumor cells, particularly in neck lymph node dissection specimens More about this image found in HPV-ASSOCIATED OROPHARYNGEAL SQUAMOUS CELL CARCINOMA WITH TUMOR CELL ANAPLA...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-7
ISBN: 978-1-933477-61-9
..., swallowing, and speaking. In head and neck pathology, it also houses a rich lymphatic network with an organized system of abundant lymph nodes which are a common site for lymphomas, infections, and metastases. The neck can be thought of in many different ways: by components and compartments including...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-2
ISBN: 978-1-933477-61-9
..., particularly at the bases, that are immature and basaloid, and feature round to oval nuclei ( 11 ). This becomes important when considering the nonkeratinizing morphology they frequently express and for the unusual clinical behavior in which the tumors metastasize to lymph nodes early and often. Clinical...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-3
ISBN: 978-1-933477-61-9
..., the pterygopalatine artery, the ascending palatine artery, and the superior pharyngeal artery. The first level of lymphatic drainage is to the lateral retropharyngeal lymph nodes (aka Rouviere nodes), and is of clinical relevance for patients with cancers of the nasopharynx ( 9 ). Staging of epithelial cancers...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-6
ISBN: 978-1-933477-61-9
... of the paucity of lymphatics in Reinke space ( 94 ). Hypopharyngeal SCC is aggressive, primarily because of a combination of an unrestricted area for tumor growth and an extensive lymphatic network. These tumors frequently have submucosal spread beneath an intact mucosa, early lymph node metastasis...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-4
ISBN: 978-1-933477-61-9
... is highly variable, ranging from small asymptomatic cancers that mimic other non-cancerous oral lesions, to depressed, ulcerated lesions, to fungating masses ( fig. 4-4 ). Approximately 40 percent of patients with OSCC present with spread to regional/cervical lymph nodes. Distant metastases are uncommon...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-8
ISBN: 978-1-933477-61-9
... helps exclude a metastatic cystic SCC, which typically affects a cervical level II lymph node and shows a thick fibrous capsule and ribbon-like distribution of atypical epithelium, characterized by a lack of maturation, cellular enlargement, and mitoses. A cholesteatoma may show a cystic space...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-1
ISBN: 978-1-933477-61-9
... historically debated, at least some are neoplastic and harbor oncogenic mutations. General Features. While RDD classically affects lymph nodes (sinus histiocytosis with massive lymphadenopathy), extranodal cases are frequent in the head and neck region, especially the sinonasal tract ( 17 – 20...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-5
ISBN: 978-1-933477-61-9
... ). They frequently involve lymph nodes as well as distant sites, including lung, brain, and bone in descending order of frequency. Microscopic Findings. Unlike metastasizing ameloblastoma, the diagnosis of AC is made histologically. There is generally high-grade cytologic atypia with pleomorphism, hypercellularity...