NIPPLE ADENOMA Figure 13-6 NIPPLE ADENOMA A: The proliferation comprising the nipple adenoma is composed of nests of epithelial cells embedded in a fibrotic stroma. In this case, there is also squamous metaplasia of the nipple ducts with an associated chronic inflammatory cell infiltrate. B,C: I... More about this image found in NIPPLE ADENOMA A: The proliferation comprising the nipple adenoma is compo...

NIPPLE ADENOMA Figure 13-8 NIPPLE ADENOMA A: Nipple adenoma with florid UDH. Necrosis is seen in the lower portion of the field. B,C: Intermediate (B) and higher (C) power shows a heterogeneous epithelial cell proliferation with slit-like spaces and an absence of cellular polarization, character... More about this image found in NIPPLE ADENOMA A: Nipple adenoma with florid UDH. Necrosis is seen in the ...

NIPPLE MARGIN Figure 15-11 NIPPLE MARGIN This low-power image illustrates a shaved, en face section of the nipple margin. This orientation permits examination of a cross-section of the nipple ducts. More about this image found in NIPPLE MARGIN This low-power image illustrates a shaved, en face section o...

NIPPLE DUCT PLICATIONS Figure 7-13 NIPPLE DUCT PLICATIONS On occasion, the anatomically normal infoldings of the nipple ducts can be sectioned in such a way that suggests intraductal papilloma. Careful attention to the location in the breast and recognition of any adjacent nipple ducts aid in app... More about this image found in NIPPLE DUCT PLICATIONS On occasion, the anatomically normal infoldings of ...

NIPPLE ADENOMA Figure 13-5 NIPPLE ADENOMA A: At low power, a papillary proliferation is present at the nipple surface; the epidermis overlying the nipple adenoma appears to be missing. B: At higher power, the papillary architecture is readily appreciated, as is the myoepithelial cell layer linin... More about this image found in NIPPLE ADENOMA A: At low power, a papillary proliferation is present at th...

NIPPLE ADENOMA Figure 13-7 NIPPLE ADENOMA A: At low power, a benign epithelial proliferation is apparent below the epidermis of the nipple. The proliferation is composed predominantly of benign papillomas and apocrine cysts. B: Higher power of the area of papillary proliferation and apocrine met... More about this image found in NIPPLE ADENOMA A: At low power, a benign epithelial proliferation is appar...

DERMIS OF NIPPLE Figure 1-11 DERMIS OF NIPPLE Low- (A) and higher- (B) power views of the dermis of the nipple demonstrating smooth muscle bundles. More about this image found in DERMIS OF NIPPLE Low- (A) and higher- (B) power views of the dermis of the...

ACCESSORY NIPPLE Figure 1-15 ACCESSORY NIPPLE This skin excision specimen from the upper abdomen has a protuberant or dome-shaped appearance; within the dermis are smooth muscle bundles. Nipple ducts, which may be present, are not seen in this section. More about this image found in ACCESSORY NIPPLE This skin excision specimen from the upper abdomen has a ...

NIPPLE ADENOMA WITH DUCTAL CARCINOMA IN SITU (DCIS) Figure 13-9 NIPPLE ADENOMA WITH DUCTAL CARCINOMA IN SITU (DCIS) A: At low power, the characteristic features of a nipple adenoma can be seen: benign-appearing epithelial elements below the nipple surface with extension into the squamous epitheli... More about this image found in NIPPLE ADENOMA WITH DUCTAL CARCINOMA IN SITU (DCIS) A: At low power, the c...

SQUAMOUS METAPLASIA OF LACTIFEROUS DUCTS Figure 13-4 SQUAMOUS METAPLASIA OF LACTIFEROUS DUCTS A: Low-power view shows squamous epithelium lining nipple ducts; some adjacent nipple ducts with the characteristic plicated contours are unaffected. B: High-power view of the squamous-lined nipple duct... More about this image found in SQUAMOUS METAPLASIA OF LACTIFEROUS DUCTS A: Low-power view shows squamous ...

LACTIFEROUS DUCTS Figure 1-12 LACTIFEROUS DUCTS At the nipple, the lactiferous ducts have a very characteristic irregular or corrugated contour on cross section. More about this image found in LACTIFEROUS DUCTS At the nipple, the lactiferous ducts have a very charact...

SYRINGOMATOUS TUMOR Figure 13-10 SYRINGOMATOUS TUMOR A: Low-power view of a punch biopsy from the nipple showing glands and nests of epithelial cells infiltrating between the smooth muscle bundles of the nipple. B,C: Intermediate (B) and higher (C) power images show solid nests and glands with r... More about this image found in SYRINGOMATOUS TUMOR A: Low-power view of a punch biopsy from the nipple sh...

INVASIVE PAGET DISEASE Figure 13-17 INVASIVE PAGET DISEASE A: A low-power image of the nipple shows malignant epithelial cells predominantly at the basal aspect of the epidermis, with overlying erosion and associated exudate. There is a brisk inflammatory cell infiltrate at the dermoepidermal jun... More about this image found in INVASIVE PAGET DISEASE A: A low-power image of the nipple shows malignant ...

INVASIVE PAGET DISEASE Figure 13-17 INVASIVE PAGET DISEASE A: A low-power image of the nipple shows malignant epithelial cells predominantly at the basal aspect of the epidermis, with overlying erosion and associated exudate. There is a brisk inflammatory cell infiltrate at the dermoepidermal jun... More about this image found in INVASIVE PAGET DISEASE A: A low-power image of the nipple shows malignant ...

TOKER CELLS Figure 13-19 TOKER CELLS Intermediate- (A) and high-power (B) images of the nipple epidermis depict scattered Toker cells with moderate amounts of clear cytoplasm and bland-appearing round nuclei. Clear keratinocytes are present in the more superficial epidermis. These cells have less... More about this image found in TOKER CELLS Intermediate- (A) and high-power (B) images of the nipple epid...

LEIOMYOMA Figure 13-20 LEIOMYOMA A: In this low-power image of a punch biopsy of a nipple mass, the nipple ducts are recognizable because of their serrated contours. Additionally, a bland spindle cell proliferation is present at the upper aspect of the image. B,C: At higher power, the characteri... More about this image found in LEIOMYOMA A: In this low-power image of a punch biopsy of a nipple mass, t...

SQUAMOUS METAPLASIA OF LACTIFEROUS DUCTS Figure 13-1 SQUAMOUS METAPLASIA OF LACTIFEROUS DUCTS A: Low-power view shows the squamous epithelial lining extending deep into the nipple duct. B,C: Intermediate- (B) and higher- (C) power views of the squamous lining of the nipple duct with consequent a... More about this image found in SQUAMOUS METAPLASIA OF LACTIFEROUS DUCTS A: Low-power view shows the squam...

SYRINGOMATOUS TUMOR Figure 13-11 SYRINGOMATOUS TUMOR A: At low power, predominantly solid nests of tumor cells are seen percolating through the dermis of the nipple. B–D: Increasing magnification of areas of the tumor showing solid nests of tumor cells (B) with some squamoid features within a fi... More about this image found in SYRINGOMATOUS TUMOR A: At low power, predominantly solid nests of tumor ce...